6TBF

Structure of a beta galactosidase with inhibitor

Summary for 6TBF

• Entry DOI: 10.2210/pdb6tbf/pdb
• Descriptor: Beta-galactosidase, putative, bgl35A, SODIUM ION, (1~{S},2~{S},3~{S},4~{R},5~{R})-4-(hydroxymethyl)-5-(octylamino)cyclopentane-1,2,3-triol, ... (5 entities in total)
• Functional Keywords: beta galactosidase, inhibitor, hydrolase
• Biological source: Cellvibrio japonicus Ueda107
• Total number of polymer chains: 8
• Total formula weight: 500850.52

Authors

Offen, W.,Davies, G. (deposition date: 2019-11-01, release date: 2020-08-19, Last modification date: 2024-01-24)

• Primary citation: Weber, P.,Thonhofer, M.,Averill, S.,Davies, G.J.,Santana, A.G.,Muller, P.,Nasseri, S.A.,Offen, W.A.,Pabst, B.M.,Paschke, E.,Schalli, M.,Torvisco, A.,Tschernutter, M.,Tysoe, C.,Windischhofer, W.,Withers, S.G.,Wolfsgruber, A.,Wrodnigg, T.M.,Stutz, A.E.; Mechanistic Insights into the Chaperoning of Human Lysosomal-Galactosidase Activity: Highly Functionalized Aminocyclopentanes and C -5a-Substituted Derivatives of 4- epi -Isofagomine.; Molecules, 25:-, 2020; PubMed: 32899288; DOI: 10.3390/molecules25174025

Experimental method

X-RAY DIFFRACTION (1.5 Å)