1NKP
 
 | | Crystal structure of Myc-Max recognizing DNA | | Descriptor: | 5'-D(*CP*GP*AP*GP*TP*AP*GP*CP*AP*CP*GP*TP*GP*CP*TP*AP*CP*TP*C)-3', Max protein, Myc proto-oncogene protein | | Authors: | Nair, S.K, Burley, S.K. | | Deposit date: | 2003-01-03 | | Release date: | 2003-02-04 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | X-ray structures of Myc-Max and Mad-Max recognizing DNA: Molecular bases of regulation by proto-oncogenic transcription factors
Cell(Cambridge,Mass.), 112, 2003
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1NLW
 | | Crystal structure of Mad-Max recognizing DNA | | Descriptor: | 5'-D(*GP*AP*GP*TP*AP*GP*CP*AP*CP*GP*TP*GP*CP*TP*AP*CP*TP*C)-3', MAD PROTEIN, MAX PROTEIN | | Authors: | Nair, S.K, Burley, S.K. | | Deposit date: | 2003-01-07 | | Release date: | 2003-02-04 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | X-ray structures of Myc-Max and Mad-Max recognizing DNA: Molecular bases of regulation by proto-oncogenic transcription factors
Cell(Cambridge,Mass.), 112, 2003
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1OKL
 | | CARBONIC ANHYDRASE II COMPLEX WITH THE 1OKL INHIBITOR 5-DIMETHYLAMINO-NAPHTHALENE-1-SULFONAMIDE | | Descriptor: | 5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... | | Authors: | Nair, S.K, Elbaum, D, Christianson, D.W. | | Deposit date: | 1996-06-25 | | Release date: | 1997-01-11 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Unexpected binding mode of the sulfonamide fluorophore 5-dimethylamino-1-naphthalene sulfonamide to human carbonic anhydrase II. Implications for the development of a zinc biosensor.
J.Biol.Chem., 271, 1996
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12CA
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1CA3
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1HEB
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1HEA
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1HEC
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1HCA
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1HED
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1YDD
 | | STRUCTURAL BASIS OF INHIBITOR AFFINITY TO VARIANTS OF HUMAN CARBONIC ANHYDRASE II | | Descriptor: | 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... | | Authors: | Nair, S.K, Christianson, D.W. | | Deposit date: | 1994-12-22 | | Release date: | 1995-02-14 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural basis of inhibitor affinity to variants of human carbonic anhydrase II.
Biochemistry, 34, 1995
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1YDC
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1YDB
 | | STRUCTURAL BASIS OF INHIBITOR AFFINITY TO VARIANTS OF HUMAN CARBONIC ANHYDRASE II | | Descriptor: | 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... | | Authors: | Nair, S.K, Christianson, D.W. | | Deposit date: | 1994-12-22 | | Release date: | 1995-02-14 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis of inhibitor affinity to variants of human carbonic anhydrase II.
Biochemistry, 34, 1995
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1YDA
 | | STRUCTURAL BASIS OF INHIBITOR AFFINITY TO VARIANTS OF HUMAN CARBONIC ANHYDRASE II | | Descriptor: | 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... | | Authors: | Nair, S.K, Christianson, D.W. | | Deposit date: | 1994-12-22 | | Release date: | 1995-02-14 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural basis of inhibitor affinity to variants of human carbonic anhydrase II.
Biochemistry, 34, 1995
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3SJM
 | | Crystal Structure Analysis of TRF2-Dbd-DNA complex | | Descriptor: | DNA (5'-D(*CP*TP*CP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*CP*CP*CP*TP*AP*AP*CP*CP*CP*TP*AP*GP*A)-3'), Telomeric repeat-binding factor 2 | | Authors: | Nair, S.K, Sliverman, S.K, Chen, J.H, Xiao, Y. | | Deposit date: | 2011-06-21 | | Release date: | 2012-10-31 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Crystal Structure Analysis of TRF2-Dbd-DNA complex
To be Published
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6UAK
 | | LahSb - C-terminal methyltransferase involved in RiPP biosynthesis | | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, SAM dependent methyltransferase LahSB | | Authors: | Nair, S.K, Estrada, P. | | Deposit date: | 2019-09-10 | | Release date: | 2019-12-04 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Characterization of a Dehydratase and Methyltransferase in the Biosynthesis of Ribosomally Synthesized and Post-translationally Modified Peptides in Lachnospiraceae.
Chembiochem, 21, 2020
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7CA2
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6WQ1
 | | Eukaryotic LanCL2 protein | | Descriptor: | LanC-like protein 2, ZINC ION | | Authors: | Nair, S.K, Garg, N. | | Deposit date: | 2020-04-28 | | Release date: | 2021-05-05 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.295 Å) | | Cite: | LanCLs add glutathione to dehydroamino acids generated at phosphorylated sites in the proteome.
Cell, 184, 2021
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2ZEY
 | | Family 16 carbohydrate binding module | | Descriptor: | CALCIUM ION, S-layer associated multidomain endoglucanase, beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-alpha-D-mannopyranose, ... | | Authors: | Nair, S.K, Bae, B. | | Deposit date: | 2007-12-18 | | Release date: | 2008-03-04 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Molecular Basis for the Selectivity and Specificity of Ligand Recognition by the Family 16 Carbohydrate-binding Modules from Thermoanaerobacterium polysaccharolyticum ManA
J.Biol.Chem., 283, 2008
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6PGN
 | | PagF single mutant with GPP | | Descriptor: | GERANYL DIPHOSPHATE, MAGNESIUM ION, PagF | | Authors: | Nair, S.K, Hao, Y, Estrada, P. | | Deposit date: | 2019-06-24 | | Release date: | 2019-07-24 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | A Single Amino Acid Switch Alters the Isoprene Donor Specificity in
Ribosomally Synthesized and Post-Translationally Modified Peptide
Prenyltransferases
J. Am. Chem. Soc., 140, 2018
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6PGM
 | | PirF geranyltransferase | | Descriptor: | PirF Geranyltransferase | | Authors: | Nair, S.K, Hao, Y, Estrada, P. | | Deposit date: | 2019-06-24 | | Release date: | 2019-07-03 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | A Single Amino Acid Switch Alters the Isoprene Donor Specificity in Ribosomally Synthesized and Post-Translationally Modified Peptide Prenyltransferases.
J.Am.Chem.Soc., 140, 2018
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1MUA
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8EJY
 | | [4+2] Aza-Cyclase F293A variant | | Descriptor: | PbtD | | Authors: | Nair, S.K. | | Deposit date: | 2022-09-19 | | Release date: | 2022-11-23 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.47 Å) | | Cite: | Enzymatic Pyridine Aromatization during Thiopeptide Biosynthesis.
J.Am.Chem.Soc., 144, 2022
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8EJZ
 | | [4+2] Aza-Cyclase Y293F variant | | Descriptor: | PbtD | | Authors: | Nair, S.K. | | Deposit date: | 2022-09-19 | | Release date: | 2022-11-23 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Enzymatic Pyridine Aromatization during Thiopeptide Biosynthesis.
J.Am.Chem.Soc., 144, 2022
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4OK2
 | | Crystal Structure of Alg17c Mutant Y258A | | Descriptor: | Putative alginate lyase, ZINC ION | | Authors: | Nair, S.K, Park, D.S. | | Deposit date: | 2014-01-21 | | Release date: | 2014-01-29 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Structure of a PL17 Family Alginate Lyase Demonstrates Functional Similarities among Exotype Depolymerases.
J.Biol.Chem., 289, 2014
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