1OKL

CARBONIC ANHYDRASE II COMPLEX WITH THE 1OKL INHIBITOR 5-DIMETHYLAMINO-NAPHTHALENE-1-SULFONAMIDE

Summary for 1OKL

Entry DOI	10.2210/pdb1okl/pdb
Descriptor	CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION, ... (5 entities in total)
Functional Keywords	lyase (oxo-acid), inhibitor, lyase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P00918
Total number of polymer chains	1
Total formula weight	29674.18
Authors	Nair, S.K.,Elbaum, D.,Christianson, D.W. (deposition date: 1996-06-25, release date: 1997-01-11, Last modification date: 2024-02-14)
Primary citation	Nair, S.K.,Elbaum, D.,Christianson, D.W. Unexpected binding mode of the sulfonamide fluorophore 5-dimethylamino-1-naphthalene sulfonamide to human carbonic anhydrase II. Implications for the development of a zinc biosensor. J.Biol.Chem., 271:1003-1007, 1996 Cited by PubMed: 8557623 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation