1D66
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![BU of 1d66 by Molmil](/molmil-images/mine/1d66) | DNA RECOGNITION BY GAL4: STRUCTURE OF A PROTEIN/DNA COMPLEX | Descriptor: | CADMIUM ION, DNA (5'-D(*CP*CP*GP*GP*AP*GP*GP*AP*CP*AP*GP*TP*CP*CP*TP*CP*C P*GP*G)-3'), DNA (5'-D(*CP*CP*GP*GP*AP*GP*GP*AP*CP*TP*GP*TP*CP*CP*TP*CP*C P*GP*G)-3'), ... | Authors: | Marmorstein, R, Carey, M, Ptashne, M, Harrison, S.C. | Deposit date: | 1992-03-06 | Release date: | 1992-03-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | DNA recognition by GAL4: structure of a protein-DNA complex. Nature, 356, 1992
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1PYI
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![BU of 1pyi by Molmil](/molmil-images/mine/1pyi) | |
4ZBJ
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![BU of 4zbj by Molmil](/molmil-images/mine/4zbj) | UBN1 peptide bound to H3.3/H4/Asf1 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Histone H3, ... | Authors: | Marmorstein, R, Ricketts, M.D, Tang, Y. | Deposit date: | 2015-04-14 | Release date: | 2015-07-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.248 Å) | Cite: | Ubinuclein-1 confers histone H3.3-specific-binding by the HIRA histone chaperone complex. Nat Commun, 6, 2015
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5T53
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![BU of 5t53 by Molmil](/molmil-images/mine/5t53) | MOLECULAR BASIS FOR COHESIN ACETYLATION BY ESTABLISHMENT OF SISTER CHROMATID COHESION N-ACETYLTRANSFERASE ESCO1 | Descriptor: | ACETYL COENZYME *A, N-acetyltransferase ESCO1, ZINC ION | Authors: | Marmorstein, R, Rivera-Colon, Y, Liszczak, G.P, Olia, A.S, Maguire, A. | Deposit date: | 2016-08-30 | Release date: | 2016-11-09 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.699 Å) | Cite: | Molecular Basis for Cohesin Acetylation by Establishment of Sister Chromatid Cohesion N-Acetyltransferase ESCO1. J. Biol. Chem., 291, 2016
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2QQG
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![BU of 2qqg by Molmil](/molmil-images/mine/2qqg) | Hst2 bound to ADP-HPD, acetyllated histone H4 and nicotinamide | Descriptor: | 5'-O-[(S)-{[(S)-{[(2R,3R,4S)-3,4-DIHYDROXYPYRROLIDIN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE, Histone H4, NAD-dependent deacetylase HST2, ... | Authors: | Marmorstein, R, Sanders, B, Zhao, K, Slama, J. | Deposit date: | 2007-07-26 | Release date: | 2007-10-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural basis for nicotinamide inhibition and base exchange in sir2 enzymes. Mol.Cell, 25, 2007
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2OD9
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![BU of 2od9 by Molmil](/molmil-images/mine/2od9) | Structural Basis for Nicotinamide Inhibition and Base Exchange in Sir2 Enzymes | Descriptor: | 5'-O-[(S)-{[(S)-{[(2R,3R,4S)-3,4-DIHYDROXYPYRROLIDIN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE, H4 peptide, NAD-dependent deacetylase HST2, ... | Authors: | Marmorstein, R, Sanders, B.D. | Deposit date: | 2006-12-21 | Release date: | 2007-02-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural basis for nicotinamide inhibition and base exchange in sir2 enzymes. Mol.Cell, 25, 2007
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2QQF
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![BU of 2qqf by Molmil](/molmil-images/mine/2qqf) | Hst2 bound to ADP-HPD and Acetylated histone H4 | Descriptor: | 5'-O-[(S)-{[(S)-{[(2R,3R,4S)-3,4-DIHYDROXYPYRROLIDIN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE, Histone H4, NAD-dependent deacetylase HST2, ... | Authors: | Marmorstein, R, Sanders, B.D, Zhao, K, Slama, J. | Deposit date: | 2007-07-26 | Release date: | 2007-10-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for nicotinamide inhibition and base exchange in sir2 enzymes. Mol.Cell, 25, 2007
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2I32
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1MX2
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![BU of 1mx2 by Molmil](/molmil-images/mine/1mx2) | Structure of F71N mutant of p18INK4c | Descriptor: | Cyclin-dependent kinase 6 inhibitor | Authors: | Marmorstein, R, Venkataramani, R.N, MacLachlan, T.K, Chai, X, El-Deiery, W.S. | Deposit date: | 2002-10-01 | Release date: | 2002-10-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structure-based design of p18INK4c proteins with increased thermodynamic stability and cell cycle inhibitory activity J.Biol.Chem., 277, 2002
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1MX6
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![BU of 1mx6 by Molmil](/molmil-images/mine/1mx6) | Structure of p18INK4c (F92N) | Descriptor: | Cyclin-dependent kinase 6 inhibitor | Authors: | Marmorstein, R, Venkataramani, R.N, MacLachlan, T.K, Chai, X, El-Deiry, W.S. | Deposit date: | 2002-10-01 | Release date: | 2002-10-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-based design of p18INK4c proteins with increased thermodynamic stability and cell cycle inhibitory activity J.Biol.Chem., 277, 2002
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1MX4
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![BU of 1mx4 by Molmil](/molmil-images/mine/1mx4) | Structure of p18INK4c (F82Q) | Descriptor: | Cyclin-dependent kinase 6 inhibitor | Authors: | Marmorstein, R, Venkataramani, R.N, MacLachlan, T.K, Chai, X, El-Deiry, W.S. | Deposit date: | 2002-10-01 | Release date: | 2002-10-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-based design of p18INK4c proteins with increased thermodynamic stability and cell cycle inhibitory activity J.Biol.Chem., 277, 2002
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3CST
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![BU of 3cst by Molmil](/molmil-images/mine/3cst) | |
3Q35
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![BU of 3q35 by Molmil](/molmil-images/mine/3q35) | Structure of the Rtt109-AcCoA/Vps75 complex and implications for chaperone-mediated histone acetylation | Descriptor: | 1,2-ETHANEDIOL, ACETYL COENZYME *A, Histone acetyltransferase, ... | Authors: | Tang, Y, Yuan, H, Meeth, K, Marmorstein, R. | Deposit date: | 2010-12-21 | Release date: | 2011-02-02 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structure of the Rtt109-AcCoA/Vps75 Complex and Implications for Chaperone-Mediated Histone Acetylation. Structure, 19, 2011
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7MX2
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7UAG
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![BU of 7uag by Molmil](/molmil-images/mine/7uag) | Structure of G6PD-WT dimer | Descriptor: | Glucose-6-phosphate 1-dehydrogenase | Authors: | Wei, X, Marmorstein, R. | Deposit date: | 2022-03-12 | Release date: | 2023-03-15 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of G6PD-WT dimer To Be Published
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6O07
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![BU of 6o07 by Molmil](/molmil-images/mine/6o07) | |
7RB3
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![BU of 7rb3 by Molmil](/molmil-images/mine/7rb3) | |
7RIG
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![BU of 7rig by Molmil](/molmil-images/mine/7rig) | Structure of ACLY-D1026A-substrates | Descriptor: | (3S)-citryl-Coenzyme A, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ... | Authors: | Wei, X, Marmorstein, R. | Deposit date: | 2021-07-19 | Release date: | 2023-05-10 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | Allosteric role of the citrate synthase homology domain of ATP citrate lyase. Nat Commun, 14, 2023
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7RKZ
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![BU of 7rkz by Molmil](/molmil-images/mine/7rkz) | Structure of ACLY D1026A-substrates-asym-int | Descriptor: | (3S)-citryl-Coenzyme A, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ... | Authors: | Wei, X, Marmorstein, R. | Deposit date: | 2021-07-22 | Release date: | 2023-05-10 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Allosteric role of the citrate synthase homology domain of ATP citrate lyase. Nat Commun, 14, 2023
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7RMP
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![BU of 7rmp by Molmil](/molmil-images/mine/7rmp) | Structure of ACLY D1026A - substrates-asym | Descriptor: | (3S)-citryl-Coenzyme A, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ... | Authors: | Wei, X, Marmorstein, R. | Deposit date: | 2021-07-28 | Release date: | 2023-05-10 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Allosteric role of the citrate synthase homology domain of ATP citrate lyase. Nat Commun, 14, 2023
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1MJA
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![BU of 1mja by Molmil](/molmil-images/mine/1mja) | Crystal structure of yeast Esa1 histone acetyltransferase domain complexed with acetyl coenzyme A | Descriptor: | COENZYME A, Esa1 protein | Authors: | Yan, Y, Harper, S, Speicher, D, Marmorstein, R. | Deposit date: | 2002-08-27 | Release date: | 2002-10-30 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | The catalytic mechanism of the ESA1 histone acetyltransferase involves a self-acetylated intermediate. Nat.Struct.Biol., 9, 2002
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1M1D
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![BU of 1m1d by Molmil](/molmil-images/mine/1m1d) | TETRAHYMENA GCN5 WITH BOUND BISUBSTRATE ANALOG INHIBITOR | Descriptor: | HISTONE H3, TGCN5 HISTONE ACETYL TRANSFERASE | Authors: | Poux, A.N, Cebrat, M, Kim, C.M, Cole, P.A, Marmorstein, R. | Deposit date: | 2002-06-18 | Release date: | 2002-10-30 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor. Proc.Natl.Acad.Sci.USA, 99, 2002
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1MJ9
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![BU of 1mj9 by Molmil](/molmil-images/mine/1mj9) | Crystal structure of yeast Esa1(C304S) mutant complexed with Coenzyme A | Descriptor: | COENZYME A, ESA1 PROTEIN, SODIUM ION | Authors: | Yan, Y, Harper, S, Speicher, D, Marmorstein, R. | Deposit date: | 2002-08-27 | Release date: | 2002-10-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The catalytic mechanism of the ESA1 histone acetyltransferase involves a self-acetylated intermediate. Nat.Struct.Biol., 9, 2002
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1MJB
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![BU of 1mjb by Molmil](/molmil-images/mine/1mjb) | Crystal structure of yeast Esa1 histone acetyltransferase E338Q mutant complexed with acetyl coenzyme A | Descriptor: | ACETYL COENZYME *A, Esa1 protein | Authors: | Yan, Y, Harper, S, Speicher, D, Marmorstein, R. | Deposit date: | 2002-08-27 | Release date: | 2002-10-30 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The catalytic mechanism of the ESA1 histone acetyltransferase involves a self-acetylated intermediate. Nat.Struct.Biol., 9, 2002
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1SZD
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![BU of 1szd by Molmil](/molmil-images/mine/1szd) | Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD+-dependent Sir2 histone/protein deacetylases | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, CHLORIDE ION, GLYCEROL, ... | Authors: | Zhao, K, Harshaw, R, Chai, X, Marmorstein, R. | Deposit date: | 2004-04-05 | Release date: | 2004-06-15 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases. Proc.Natl.Acad.Sci.Usa, 101, 2004
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