4M6R
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![BU of 4m6r by Molmil](/molmil-images/mine/4m6r) | Structural and biochemical basis for the inhibition of cell death by APIP, a methionine salvage enzyme | Descriptor: | Methylthioribulose-1-phosphate dehydratase, ZINC ION | Authors: | Kang, W, Hong, S.H, Lee, H.M, Kim, N.Y, Lim, Y.C, Le, L.T.M, Lim, B, Kim, H.C, Kim, T.Y, Ashida, H, Yokota, A, Hah, S.S, Chun, K.H, Jung, Y.K, Yang, J.K. | Deposit date: | 2013-08-10 | Release date: | 2014-01-29 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and biochemical basis for the inhibition of cell death by APIP, a methionine salvage enzyme. Proc.Natl.Acad.Sci.USA, 111, 2014
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6UG0
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![BU of 6ug0 by Molmil](/molmil-images/mine/6ug0) | N2-bound Nitrogenase MoFe-protein from Azotobacter vinelandii | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (III) ION, FE(8)-S(7) CLUSTER, ... | Authors: | Kang, W, Hu, Y, Ribbe, M.W. | Deposit date: | 2019-09-25 | Release date: | 2020-06-24 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Structural evidence for a dynamic metallocofactor during N2reduction by Mo-nitrogenase. Science, 368, 2020
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6VXT
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![BU of 6vxt by Molmil](/molmil-images/mine/6vxt) | Activated Nitrogenase MoFe-protein from Azotobacter vinelandii | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (III) ION, FE(8)-S(7) CLUSTER, ... | Authors: | Kang, W, Hu, Y, Ribbe, M.W. | Deposit date: | 2020-02-24 | Release date: | 2020-06-24 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Structural evidence for a dynamic metallocofactor during N2reduction by Mo-nitrogenase. Science, 368, 2020
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8KG2
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![BU of 8kg2 by Molmil](/molmil-images/mine/8kg2) | |
7JMA
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![BU of 7jma by Molmil](/molmil-images/mine/7jma) | |
7JMB
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![BU of 7jmb by Molmil](/molmil-images/mine/7jmb) | Crystal structure of Nitrogenase iron-molybdenum cofactor biosynthesis enzyme NifB from Methanothermobacter thermautotrophicus with three Fe4S4 clusters | Descriptor: | IRON/SULFUR CLUSTER, Nitrogenase iron-molybdenum cofactor biosynthesis protein NifB | Authors: | Kang, W, Rettberg, L, Ribbe, M.W, Hu, Y. | Deposit date: | 2020-07-31 | Release date: | 2020-10-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | X-Ray Crystallographic Analysis of NifB with a Full Complement of Clusters: Structural Insights into the Radical SAM-Dependent Carbide Insertion During Nitrogenase Cofactor Assembly. Angew.Chem.Int.Ed.Engl., 60, 2021
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7MCI
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![BU of 7mci by Molmil](/molmil-images/mine/7mci) | MoFe protein from Azotobacter vinelandii with a sulfur-replenished cofactor | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, CALCIUM ION, FE(8)-S(7) CLUSTER, ... | Authors: | Kang, W, Lee, C, Hu, Y, Ribbe, M.W. | Deposit date: | 2021-04-02 | Release date: | 2022-05-18 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Evidence of substrate binding and product release via belt-sulfur mobilization of the nitrogenase cofactor Nat Catal, 5, 2022
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8HL6
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![BU of 8hl6 by Molmil](/molmil-images/mine/8hl6) | |
8HL7
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![BU of 8hl7 by Molmil](/molmil-images/mine/8hl7) | |
3QCA
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![BU of 3qca by Molmil](/molmil-images/mine/3qca) | |
8K1G
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![BU of 8k1g by Molmil](/molmil-images/mine/8k1g) | |
8K1H
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8JGA
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![BU of 8jga by Molmil](/molmil-images/mine/8jga) | Cryo-EM structure of Mi3 fused with FKBP | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1A,2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase | Authors: | Zhang, H.W, Kang, W, Xue, C. | Deposit date: | 2023-05-20 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.68 Å) | Cite: | Dynamic Metabolons Using Stimuli-Responsive Protein Cages. J.Am.Chem.Soc., 146, 2024
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8JGC
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![BU of 8jgc by Molmil](/molmil-images/mine/8jgc) | Cryo-EM structure of Mi3 fused with LOV2 | Descriptor: | LOV domain-containing protein,2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase | Authors: | Zhang, H.W, Kang, W, Xue, C. | Deposit date: | 2023-05-20 | Release date: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.44 Å) | Cite: | Dynamic Metabolons Using Stimuli-Responsive Protein Cages. J.Am.Chem.Soc., 146, 2024
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6NZJ
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![BU of 6nzj by Molmil](/molmil-images/mine/6nzj) | Structural Analysis of a Nitrogenase Iron Protein from Methanosarcina acetivorans: Implications for CO2 Capture by a Surface-Exposed [Fe4S4] Cluster | Descriptor: | IRON/SULFUR CLUSTER, Nitrogenase iron protein, SULFATE ION | Authors: | Rettberg, L.A, Kang, W, Stiebritz, M.T, Hiller, C.J, Lee, C.C, Liedtke, J, Ribbe, M.W, Hu, Y. | Deposit date: | 2019-02-13 | Release date: | 2019-06-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Analysis of a Nitrogenase Iron Protein from Methanosarcina acetivorans: Implications for CO 2 Capture by a Surface-Exposed [Fe 4 S 4 ] Cluster. Mbio, 10, 2019
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6O0B
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![BU of 6o0b by Molmil](/molmil-images/mine/6o0b) | Structural and Mechanistic Insights into CO2 Activation by Nitrogenase Iron Protein | Descriptor: | IRON/SULFUR CLUSTER, Nitrogenase iron protein | Authors: | Rettberg, L.A, Stiebritz, M.T, Kang, W, Lee, C.C, Ribbe, M.W, Hu, Y. | Deposit date: | 2019-02-15 | Release date: | 2019-09-04 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural and Mechanistic Insights into CO2Activation by Nitrogenase Iron Protein. Chemistry, 25, 2019
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3QC8
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![BU of 3qc8 by Molmil](/molmil-images/mine/3qc8) | Crystal Structure of FAF1 UBX Domain In Complex with p97/VCP N Domain Reveals The Conserved FcisP Touch-Turn Motif of UBX Domain Suffering Conformational Change | Descriptor: | FAS-associated factor 1, Transitional endoplasmic reticulum ATPase | Authors: | Kim, K.H, Kang, W, Suh, S.W, Yang, J.K. | Deposit date: | 2011-01-15 | Release date: | 2011-07-20 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of FAF1 UBX domain in complex with p97/VCP N domain reveals a conformational change in the conserved FcisP touch-turn motif of UBX domain Proteins, 79, 2011
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8HRZ
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![BU of 8hrz by Molmil](/molmil-images/mine/8hrz) | |
7VID
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![BU of 7vid by Molmil](/molmil-images/mine/7vid) | |
7WWP
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![BU of 7wwp by Molmil](/molmil-images/mine/7wwp) | Crystal structure of human Npl4 | Descriptor: | Nuclear protein localization protein 4 homolog, ZINC ION | Authors: | Nguyen, T.Q, Le, L.T.M, Kim, D.H, Ko, K.S, Lee, H.T, Nguyen, Y.T.K, Kim, H.S, Han, B.W, Kang, W, Yang, J.K. | Deposit date: | 2022-02-14 | Release date: | 2022-09-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | Structural basis for the interaction between human Npl4 and Npl4-binding motif of human Ufd1. Structure, 30, 2022
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7WWQ
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![BU of 7wwq by Molmil](/molmil-images/mine/7wwq) | Crystal structure of human Ufd1-Npl4 complex | Descriptor: | Nuclear protein localization protein 4 homolog, Ubiquitin recognition factor in ER-associated degradation protein 1 | Authors: | Nguyen, T.Q, Le, L.T.M, Kim, D.H, Ko, K.S, Lee, H.T, Nguyen, Y.T.K, Kim, H.S, Han, B.W, Kang, W, Yang, J.K. | Deposit date: | 2022-02-14 | Release date: | 2022-09-21 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Structural basis for the interaction between human Npl4 and Npl4-binding motif of human Ufd1. Structure, 30, 2022
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8GZ9
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![BU of 8gz9 by Molmil](/molmil-images/mine/8gz9) | Cryo-EM structure of Abeta2 fibril polymorph2 | Descriptor: | peptide self-assembled antimicrobial fibrils | Authors: | Xia, W.C, Zhang, M.M, Liu, C. | Deposit date: | 2022-09-26 | Release date: | 2023-09-20 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.62 Å) | Cite: | Engineering of antimicrobial peptide fibrils with feedback degradation of bacterial-secreted enzymes. Chem Sci, 14, 2023
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8GZ8
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![BU of 8gz8 by Molmil](/molmil-images/mine/8gz8) | Cryo-EM structure of Abeta2 fibril polymorph1 | Descriptor: | peptide self-assembled antimicrobial fibrils | Authors: | Xia, W.C, Zhang, M.M, Liu, C. | Deposit date: | 2022-09-26 | Release date: | 2023-09-20 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.35 Å) | Cite: | Engineering of antimicrobial peptide fibrils with feedback degradation of bacterial-secreted enzymes. Chem Sci, 14, 2023
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8IBQ
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![BU of 8ibq by Molmil](/molmil-images/mine/8ibq) | Bromodomain and Extra-terminal Domain (BET) BRD4 | Descriptor: | 7-[2-fluoranyl-3-(1,3,5-trimethylpyrazol-4-yl)phenyl]-1~{H}-imidazo[4,5-b]pyridine, Bromodomain-containing protein 4 | Authors: | Cao, D, Zhiyan, D, Xiong, B. | Deposit date: | 2023-02-10 | Release date: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Discovery of 1 H -Imidazo[4,5- b ]pyridine Derivatives as Potent and Selective BET Inhibitors for the Management of Neuropathic Pain. J.Med.Chem., 66, 2023
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8IDH
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![BU of 8idh by Molmil](/molmil-images/mine/8idh) | Bromodomain and Extra-terminal Domain (BET) BRD4 | Descriptor: | 7-[2-fluoranyl-3-(1,3,5-trimethylpyrazol-4-yl)phenyl]-1~{H}-imidazo[4,5-b]pyridine, Bromodomain-containing protein 4 | Authors: | Cao, D, Zhiyan, D, Xiong, B. | Deposit date: | 2023-02-13 | Release date: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Discovery of 1 H -Imidazo[4,5- b ]pyridine Derivatives as Potent and Selective BET Inhibitors for the Management of Neuropathic Pain. J.Med.Chem., 66, 2023
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