1DDF
 
 | | FAS DEATH DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE | | Descriptor: | FAS | | Authors: | Huang, B, Eberstadt, M, Olejniczak, E, Meadows, R.P, Fesik, S. | | Deposit date: | 1996-11-08 | | Release date: | 1997-11-12 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | NMR structure and mutagenesis of the Fas (APO-1/CD95) death domain.
Nature, 384, 1996
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1Y7L
 | | O-Acetylserine Sulfhydrylase Complex | | Descriptor: | O-acetylserine sulfhydrylase, SULFATE ION, decamer fragment of Serine acetyltransferase | | Authors: | Huang, B, Vetting, M.W, Roderick, S.L. | | Deposit date: | 2004-12-09 | | Release date: | 2005-04-26 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | The active site of O-acetylserine sulfhydrylase is the anchor point for bienzyme complex formation with serine acetyltransferase.
J.Bacteriol., 187, 2005
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3KXL
 | | crystal structure of SsGBP mutation variant G235S | | Descriptor: | GTP-binding protein (HflX), THIOCYANATE ION | | Authors: | Huang, B, Li, X, Zhang, X.C, Rao, Z. | | Deposit date: | 2009-12-03 | | Release date: | 2010-05-26 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Functional study on GTP hydrolysis by the GTP binding protein from Sulfolobus solfataricus, a member of the HflX family.
J.Biochem., 2010
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3KXI
 | | crystal structure of SsGBP and GDP complex | | Descriptor: | GTP-binding protein (HflX), GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Huang, B, Li, X, Zhang, X.C, Rao, Z. | | Deposit date: | 2009-12-03 | | Release date: | 2010-05-26 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Functional study on GTP hydrolysis by the GTP binding protein from Sulfolobus solfataricus, a member of the HflX family.
J.Biochem., 2010
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3KXK
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5IE8
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7WSK
 | | Crystal structure of SARS-CoV-2 Omicron spike receptor-binding domain in complex with civet ACE2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike protein S1, ... | | Authors: | Huang, B, Han, P, Qi, J. | | Deposit date: | 2022-01-29 | | Release date: | 2022-06-08 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Broader-species receptor binding and structural bases of Omicron SARS-CoV-2 to both mouse and palm-civet ACE2s.
Cell Discov, 8, 2022
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1IRS
 | | IRS-1 PTB DOMAIN COMPLEXED WITH A IL-4 RECEPTOR PHOSPHOPEPTIDE, NMR, MINIMIZED AVERAGE STRUCTURE | | Descriptor: | IL-4 RECEPTOR PHOSPHOPEPTIDE, IRS-1 | | Authors: | Zhou, M.-M, Huang, B, Olejniczak, E.T, Meadows, R.P, Shuker, S.B, Miyazaki, M, Trub, T, Shoelson, S.E, Feisk, S.W. | | Deposit date: | 1996-03-22 | | Release date: | 1997-05-15 | | Last modified: | 2024-10-09 | | Method: | SOLUTION NMR | | Cite: | Structural basis for IL-4 receptor phosphopeptide recognition by the IRS-1 PTB domain.
Nat.Struct.Biol., 3, 1996
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8CXB
 | | Human PA28-20S (PA28-4a3b) | | Descriptor: | Proteasome activator complex subunit 1, Proteasome activator complex subunit 2, Proteasome subunit alpha type-1, ... | | Authors: | Zhao, J, Makhija, S, Huang, B, Cheng, Y. | | Deposit date: | 2022-05-20 | | Release date: | 2022-11-02 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins.
Proc.Natl.Acad.Sci.USA, 119, 2022
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1A1W
 | | FADD DEATH EFFECTOR DOMAIN, F25Y MUTANT, NMR MINIMIZED AVERAGE STRUCTURE | | Descriptor: | FADD PROTEIN | | Authors: | Eberstadt, M, Huang, B, Chen, Z, Meadows, R.P, Ng, C, Fesik, S.W. | | Deposit date: | 1997-12-18 | | Release date: | 1998-12-30 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | NMR structure and mutagenesis of the FADD (Mort1) death-effector domain.
Nature, 392, 1998
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1A1Z
 | | FADD DEATH EFFECTOR DOMAIN, F25G MUTANT, NMR MINIMIZED AVERAGE STRUCTURE | | Descriptor: | FADD PROTEIN | | Authors: | Eberstadt, M, Huang, B, Chen, Z, Meadows, R.P, Ng, C, Fesik, S.W. | | Deposit date: | 1997-12-18 | | Release date: | 1998-12-30 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | NMR structure and mutagenesis of the FADD (Mort1) death-effector domain.
Nature, 392, 1998
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3HVN
 | | Crystal structure of cytotoxin protein suilysin from Streptococcus suis | | Descriptor: | 1,1,1,3,3,3-hexafluoropropan-2-ol, HEPTANE-1,2,3-TRIOL, Hemolysin | | Authors: | Xu, L, Huang, B, Du, H, Zhang, C.X, Xu, J, Li, X, Rao, Z. | | Deposit date: | 2009-06-16 | | Release date: | 2010-03-02 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.852 Å) | | Cite: | Crystal structure of cytotoxin protein suilysin from Streptococcus suis.
Protein Cell, 1, 2010
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1SST
 | | Serine Acetyltransferase- Complex with CoA | | Descriptor: | COENZYME A, Serine acetyltransferase | | Authors: | Olsen, L.R, Huang, B, Vetting, M.W, Roderick, S.L. | | Deposit date: | 2004-03-24 | | Release date: | 2004-06-01 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of Serine Acetyltransferase in Complexes with CoA and its Cysteine Feedback Inhibitor
Biochemistry, 43, 2004
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1SSQ
 | | Serine Acetyltransferase- Complex with Cysteine | | Descriptor: | CYSTEINE, MAGNESIUM ION, Serine acetyltransferase | | Authors: | Olsen, L.R, Huang, B, Vetting, M.W, Roderick, S.L. | | Deposit date: | 2004-03-24 | | Release date: | 2004-06-01 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structure of Serine Acetyltransferase in Complexes with CoA and its Cysteine Feedback Inhibitor
Biochemistry, 43, 2004
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1SSM
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3RLQ
 | | Co-crystal structure of the HSP90 ATP binding domain in complex with 4-(2,4-dichloro-5-methoxyphenyl)-2-methyl-7H-pyrrolo[2,3-d]pyrimidine-5- carbonitrile | | Descriptor: | 4-(2,4-dichloro-5-methoxyphenyl)-2-methyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, Heat shock protein HSP 90-alpha, PHOSPHATE ION | | Authors: | Kung, P.-P, Sinnema, P.-J, Richardson, P, Hickey, M.J, Gajiwala, K.S, Wang, F, Huang, B, McClellan, G, Wang, J, Maegley, K, Bergqvist, S, Mehta, P.P, Kania, R. | | Deposit date: | 2011-04-20 | | Release date: | 2011-06-08 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Design strategies to target crystallographic waters applied to the Hsp90 molecular chaperone.
Bioorg.Med.Chem.Lett., 21, 2011
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3RLP
 | | Co-crystal structure of the HSP90 ATP binding domain in complex with 4-(2,4-dichloro-5-methoxyphenyl)-6-methylpyrimidin-2-amine | | Descriptor: | 4-(2,4-dichloro-5-methoxyphenyl)-6-methylpyrimidin-2-amine, Heat shock protein HSP 90-alpha, PHOSPHATE ION | | Authors: | Kung, P.-P, Sinnema, P.-J, Richardson, P, Hickey, M.J, Gajiwala, K.S, Wang, F, Huang, B, McClellan, G, Wang, J, Maegley, K, Bergqvist, S, Mehta, P.P, Kania, R. | | Deposit date: | 2011-04-20 | | Release date: | 2011-06-08 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Design strategies to target crystallographic waters applied to the Hsp90 molecular chaperone.
Bioorg.Med.Chem.Lett., 21, 2011
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3RLR
 | | Co-crystal structure of the HSP90 ATP binding domain in complex with 4-(2,4-dichloro-5-methoxyphenyl)-2,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | | Descriptor: | 4-(2,4-dichloro-5-methoxyphenyl)-2,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, Heat shock protein HSP 90-alpha, PHOSPHATE ION | | Authors: | Kung, P.-P, Sinnema, P.-J, Richardson, P, Hickey, M.J, Gajiwala, K.S, Wang, F, Huang, B, McClellan, G, Wang, J, Maegley, K, Bergqvist, S, Mehta, P.P, Kania, R. | | Deposit date: | 2011-04-20 | | Release date: | 2011-06-08 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Design strategies to target crystallographic waters applied to the Hsp90 molecular chaperone.
Bioorg.Med.Chem.Lett., 21, 2011
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7NAQ
 | | Human PA200-20S proteasome complex | | Descriptor: | INOSITOL HEXAKISPHOSPHATE, Proteasome activator complex subunit 4, Proteasome subunit alpha type-1, ... | | Authors: | Zhao, J, Makhija, S, Huang, B, Cheng, Y. | | Deposit date: | 2021-06-22 | | Release date: | 2022-11-02 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7NAP
 | | Human PA28-20S-PA28 proteasome complex | | Descriptor: | Proteasome activator complex subunit 1, Proteasome activator complex subunit 2, Proteasome subunit alpha type-1, ... | | Authors: | Zhao, J, Makhija, S, Huang, B, Cheng, Y. | | Deposit date: | 2021-06-22 | | Release date: | 2022-11-02 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7NAO
 | | Human PA28-20S proteasome complex | | Descriptor: | Proteasome activator complex subunit 1, Proteasome activator complex subunit 2, Proteasome subunit alpha type-1, ... | | Authors: | Zhao, J, Makhija, S, Huang, B, Cheng, Y. | | Deposit date: | 2021-06-22 | | Release date: | 2022-11-02 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7NAN
 | | Human 20S proteasome core particle | | Descriptor: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | | Authors: | Zhao, J, Makhija, S, Huang, B, Cheng, Y. | | Deposit date: | 2021-06-22 | | Release date: | 2022-11-02 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins.
Proc.Natl.Acad.Sci.USA, 119, 2022
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8JCB
 | | Vgamma5 Vdelta1 T cell receptor complex | | Descriptor: | T cell receptor delta variable 1,T cell receptor delta constant, T cell receptor gamma variable 5,T cell receptor gamma constant 1, T-cell surface glycoprotein CD3 delta chain, ... | | Authors: | Xin, W, Huang, B, Chi, X, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q. | | Deposit date: | 2023-05-10 | | Release date: | 2024-05-08 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (9.5 Å) | | Cite: | Structures of human gamma delta T cell receptor-CD3 complex.
Nature, 630, 2024
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8JBV
 | | Extracellular domain of gamma delta TCR | | Descriptor: | T cell receptor delta variable 1,T cell receptor delta constant, T cell receptor gamma variable 5,T cell receptor gamma constant 1 | | Authors: | Xin, W, Chi, X, Huang, B, Su, Q, Zhou, Q. | | Deposit date: | 2023-05-09 | | Release date: | 2024-05-08 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.02 Å) | | Cite: | Structures of human gamma delta T cell receptor-CD3 complex.
Nature, 630, 2024
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8JC0
 | | V gamma9 V delta2 TCR and CD3 complex in LMNG | | Descriptor: | CHOLESTEROL, T cell receptor delta variable 2,T cell receptor delta constant, T cell receptor gamma variable 9,T cell receptor gamma constant 1, ... | | Authors: | Xin, W, Huang, B, Chi, X, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q. | | Deposit date: | 2023-05-10 | | Release date: | 2024-05-08 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structures of human gamma delta T cell receptor-CD3 complex.
Nature, 630, 2024
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