7EN4
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![BU of 7en4 by Molmil](/molmil-images/mine/7en4) | Multi-state structure determination and dynamics analysis elucidate a new ubiquitin-recognition mechanism of yeast ubiquitin C-terminal hydrolase. | Descriptor: | Ubiquitin carboxyl-terminal hydrolase YUH1 | Authors: | Okada, M, Tateishi, Y, Nojiri, E, Mikawa, T, Rajesh, S, Ogasawa, H, Ueda, T, Yagi, H, Kohno, T, Kigawa, T, Shimada, I, Guentert, P, Yutaka, I, Ikeya, T. | Deposit date: | 2021-04-15 | Release date: | 2022-04-20 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Multi-state structure determination and dynamics analysis elucidate a new ubiquitin-recognition mechanism of yeast ubiquitin C-terminal hydrolase. To Be Published
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5C5A
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![BU of 5c5a by Molmil](/molmil-images/mine/5c5a) | Crystal Structure of HDM2 in complex with Nutlin-3a | Descriptor: | 4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one, CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, ... | Authors: | Orts, J, Waelti, M.A, Marsh, M, Vera, L, Gossert, A.D, Guentert, P, Riek, R. | Deposit date: | 2015-06-19 | Release date: | 2016-06-29 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.146 Å) | Cite: | NMR Molecular Replacement, NMR2 To Be Published
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8OX2
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![BU of 8ox2 by Molmil](/molmil-images/mine/8ox2) | BRICHOS trimer | Descriptor: | Pulmonary surfactant-associated protein C | Authors: | Ghosh, D, Torres, F, Guentert, P, Riek, R. | Deposit date: | 2023-04-30 | Release date: | 2024-06-26 | Method: | SOLUTION NMR | Cite: | The inhibitory action of the chaperone BRICHOS against the alpha-Synuclein secondary nucleation pathway at near-atomic resolution To Be Published
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8OVI
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![BU of 8ovi by Molmil](/molmil-images/mine/8ovi) | BRICHOS monomer | Descriptor: | Pulmonary surfactant-associated protein C (Fragment) | Authors: | Ghosh, D, Torres, F, Guentert, P, Riek, R. | Deposit date: | 2023-04-26 | Release date: | 2024-06-26 | Method: | SOLUTION NMR | Cite: | The inhibitory action of the chaperone BRICHOS against the alpha-Synuclein secondary nucleation pathway at near-atomic resolution To Be Published
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2H3S
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![BU of 2h3s by Molmil](/molmil-images/mine/2h3s) | cis-Azobenzene-avian pancreatic polypeptide bound to DPC micelles | Descriptor: | (3-{(Z)-[3-(AMINOMETHYL)PHENYL]DIAZENYL}PHENYL)ACETIC ACID, Pancreatic hormone | Authors: | Jurt, S, Aemissegger, A, Guentert, P, Zerbe, O, Hilvert, D. | Deposit date: | 2006-05-23 | Release date: | 2006-09-12 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | A Photoswitchable Miniprotein Based on the Sequence of Avian Pancreatic Polypeptide Angew.Chem.Int.Ed.Engl., 45, 2006
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2H3T
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![BU of 2h3t by Molmil](/molmil-images/mine/2h3t) | trans-(4-aminomethyl)phenylazobenzoic acid-aPP bound to DPC micelles | Descriptor: | (3-{(E)-[3-(AMINOMETHYL)PHENYL]DIAZENYL}PHENYL)ACETIC ACID, Pancreatic hormone | Authors: | Jurt, S, Aemissegger, A, Guentert, P, Zerbe, O, Hilvert, D. | Deposit date: | 2006-05-23 | Release date: | 2006-09-12 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | A Photoswitchable Miniprotein Based on the Sequence of Avian Pancreatic Polypeptide Angew.Chem.Int.Ed.Engl., 45, 2006
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2H4B
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![BU of 2h4b by Molmil](/molmil-images/mine/2h4b) | cis-4-aminomethylphenylazobenzoic acid-avian pancreatic polypeptide | Descriptor: | (3-{(Z)-[3-(AMINOMETHYL)PHENYL]DIAZENYL}PHENYL)ACETIC ACID, Pancreatic hormone | Authors: | Jurt, S, Aemissegger, A, Guentert, P, Zerbe, O, Hilvert, D. | Deposit date: | 2006-05-24 | Release date: | 2006-09-12 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | A Photoswitchable Miniprotein Based on the Sequence of Avian Pancreatic Polypeptide Angew.Chem.Int.Ed.Engl., 45, 2006
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1MO8
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![BU of 1mo8 by Molmil](/molmil-images/mine/1mo8) | ATPase | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Sodium/Potassium-Transporting ATPase alpha-1 | Authors: | Hilge, M, Siegal, G, Vuister, G.W, Guentert, P, Gloor, S.M, Abrahams, J.P. | Deposit date: | 2002-09-08 | Release date: | 2003-06-10 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | ATP-induced conformational changes of the nucleotide-binding domain of Na,K-ATPase Nat.Struct.Biol., 10, 2003
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1JAS
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![BU of 1jas by Molmil](/molmil-images/mine/1jas) | HsUbc2b | Descriptor: | UBIQUITIN-CONJUGATING ENZYME E2-17 KDA | Authors: | Miura, T, Klaus, W, Ross, A, Guentert, P, Senn, H. | Deposit date: | 2001-05-31 | Release date: | 2003-09-09 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The NMR structure of the class I human ubiquitin-conjugating enzyme 2b J.Biomol.NMR, 22, 2002
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1MO7
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![BU of 1mo7 by Molmil](/molmil-images/mine/1mo7) | ATPase | Descriptor: | Sodium/Potassium-transporting ATPase alpha-1 chain | Authors: | Hilge, M, Siegal, G, Vuister, G.W, Guentert, P, Gloor, S.M, Abrahams, J.P. | Deposit date: | 2002-09-08 | Release date: | 2003-06-03 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | ATP-induced conformational changes of the nucleotide-binding domain of Na,K-ATPase Nat.Struct.Biol., 10, 2003
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2DT6
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![BU of 2dt6 by Molmil](/molmil-images/mine/2dt6) | Solution structure of the first SURP domain of human splicing factor SF3a120 | Descriptor: | Splicing factor 3 subunit 1 | Authors: | Kuwasako, K, He, F, Inoue, M, Tanaka, A, Sugano, S, Guentert, P, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-07-11 | Release date: | 2006-12-26 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structures of the SURP domains and the subunit-assembly mechanism within the splicing factor SF3a complex in 17S U2 snRNP Structure, 14, 2006
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2N9K
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![BU of 2n9k by Molmil](/molmil-images/mine/2n9k) | 1H, 13C, and 15N Chemical Shift Assignments for in vitro GB1 | Descriptor: | Immunoglobulin G-binding protein G | Authors: | Ikeya, T, Hanashima, T, Hosoya, S, Shimazaki, M, Ikeda, S, Mishima, M, Guentert, P, Ito, Y. | Deposit date: | 2015-11-26 | Release date: | 2016-12-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Improved in-cell structure determination of proteins at near-physiological concentration Sci Rep, 6, 2016
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2N9L
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![BU of 2n9l by Molmil](/molmil-images/mine/2n9l) | 1H, 13C, and 15N Chemical Shift Assignments for in-cell GB1 | Descriptor: | Immunoglobulin G-binding protein G | Authors: | Ikeya, T, Hanashima, T, Hosoya, S, Shimazaki, M, Ikeda, S, Mishima, M, Guentert, P, Ito, Y. | Deposit date: | 2015-11-30 | Release date: | 2016-12-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Improved in-cell structure determination of proteins at near-physiological concentration Sci Rep, 6, 2016
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1WLN
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![BU of 1wln by Molmil](/molmil-images/mine/1wln) | |
4MRT
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![BU of 4mrt by Molmil](/molmil-images/mine/4mrt) | Structure of the Phosphopantetheine Transferase Sfp in Complex with Coenzyme A and a Peptidyl Carrier Protein | Descriptor: | 4'-phosphopantetheinyl transferase sfp, COENZYME A, GLYCEROL, ... | Authors: | Tufar, P, Rahighi, S, Kraas, F.I, Kirchner, D.K, Loehr, F, Henrich, E, Koepke, J, Dikic, I, Guentert, P, Marahiel, M.A, Doetsch, V. | Deposit date: | 2013-09-17 | Release date: | 2014-04-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of a PCP/Sfp Complex Reveals the Structural Basis for Carrier Protein Posttranslational Modification. Chem.Biol., 21, 2014
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6H8C
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![BU of 6h8c by Molmil](/molmil-images/mine/6h8c) | Structure of the human GABARAPL2 protein in complex with the UBA5 LIR motif | Descriptor: | Gamma-aminobutyric acid receptor-associated protein-like 2, Ubiquitin-like modifier-activating enzyme 5 | Authors: | Huber, J, Loehr, F, Gruber, J, Akutsu, M, Guentert, P, Doetsch, V, Rogov, V.V. | Deposit date: | 2018-08-02 | Release date: | 2019-05-01 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | An atypical LIR motif within UBA5 (ubiquitin like modifier activating enzyme 5) interacts with GABARAP proteins and mediates membrane localization of UBA5. Autophagy, 16, 2020
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8KCQ
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![BU of 8kcq by Molmil](/molmil-images/mine/8kcq) | Solution structures of the N-terminal divergent caplonin homology (NN-CH) domains of human intraflagellar transport protein 54 | Descriptor: | TRAF3-interacting protein 1 | Authors: | Dang, W, Kuwasako, K, He, F, Takahashi, M, Tsuda, K, Nagata, T, Tanaka, A, Kobayashi, N, Kigawa, T, Guentert, P, Shirouzu, M, Yokoyama, S, Muto, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2023-08-08 | Release date: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | 1 H, 13 C, and 15 N resonance assignments and solution structure of the N-terminal divergent calponin homology (NN-CH) domain of human intraflagellar transport protein 54. Biomol.Nmr Assign., 18, 2024
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7QCX
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![BU of 7qcx by Molmil](/molmil-images/mine/7qcx) | Two-state liquid NMR Structure of a PDZ2 Domain from hPTP1E, apo form | Descriptor: | Tyrosine-protein phosphatase non-receptor type 13 | Authors: | Ashkinadze, D, Kadavath, H, Chi, C, Friedmann, M, Strotz, D, Kumari, P, Minges, M, Cadalbert, R, Koenigl, S, Guentert, P, Voegeli, B, Riek, R. | Deposit date: | 2021-11-25 | Release date: | 2022-09-07 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Atomic resolution protein allostery from the multi-state structure of a PDZ domain. Nat Commun, 13, 2022
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7QCY
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![BU of 7qcy by Molmil](/molmil-images/mine/7qcy) | Two-state liquid NMR Structure of a PDZ2 Domain from hPTP1E, complexed with RA-GEF2 peptide | Descriptor: | Tyrosine-protein phosphatase non-receptor type 13 | Authors: | Ashkinadze, D, Kadavath, H, Chi, C, Friedmann, M, Strotz, D, Kumari, P, Minges, M, Cadalbert, R, Koenigl, S, Guentert, P, Voegeli, B, Riek, R. | Deposit date: | 2021-11-25 | Release date: | 2022-09-07 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Atomic resolution protein allostery from the multi-state structure of a PDZ domain. Nat Commun, 13, 2022
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5N2O
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![BU of 5n2o by Molmil](/molmil-images/mine/5n2o) | Structure Of P63 SAM Domain L514F Mutant Causative Of AEC Syndrome | Descriptor: | Tumor protein 63 | Authors: | Rinnenthal, J, Wuerz, J.M, Osterburg, C, Guentert, P, Doetsch, V. | Deposit date: | 2017-02-08 | Release date: | 2018-02-07 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Protein aggregation of the p63 transcription factor underlies severe skin fragility in AEC syndrome. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6TUB
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![BU of 6tub by Molmil](/molmil-images/mine/6tub) | Beta-endorphin amyloid fibril | Descriptor: | Beta-endorphin | Authors: | Verasdonck, J, Seuring, C, Gath, J, Ghosh, D, Nespovitaya, N, Waelti, M.A, Maji, S, Cadalbert, R, Boeckmann, A, Guentert, P, Meier, B.H, Riek, R. | Deposit date: | 2020-01-05 | Release date: | 2020-10-28 | Last modified: | 2024-05-15 | Method: | SOLID-STATE NMR | Cite: | The three-dimensional structure of human beta-endorphin amyloid fibrils. Nat.Struct.Mol.Biol., 27, 2020
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5ZCZ
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![BU of 5zcz by Molmil](/molmil-images/mine/5zcz) | Solution structure of the T. Thermophilus HB8 TTHA1718 protein in living eukaryotic cells by in-cell NMR spectroscopy | Descriptor: | Heavy metal binding protein | Authors: | Tanaka, T, Teppei, I, Kamoshida, H, Mishima, M, Shirakawa, M, Guentert, P, Ito, Y. | Deposit date: | 2018-02-22 | Release date: | 2019-08-21 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | High-Resolution Protein 3D Structure Determination in Living Eukaryotic Cells. Angew.Chem.Int.Ed.Engl., 58, 2019
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5ZD0
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![BU of 5zd0 by Molmil](/molmil-images/mine/5zd0) | Solution structure of human ubiquitin with three alanine mutations in living eukaryotic cells by in-cell NMR spectroscopy | Descriptor: | ubiquitin | Authors: | Tanaka, T, Ikeya, T, Kamoshida, H, Mishima, M, Shirakawa, M, Guentert, P, Ito, Y. | Deposit date: | 2018-02-22 | Release date: | 2019-08-21 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | High-Resolution Protein 3D Structure Determination in Living Eukaryotic Cells. Angew.Chem.Int.Ed.Engl., 58, 2019
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5Z4B
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![BU of 5z4b by Molmil](/molmil-images/mine/5z4b) | GB1 structure determination in living eukaryotic cells by in-cell NMR spectroscopy | Descriptor: | Protein LG | Authors: | Tanaka, T, Teppei, I, Kamoshida, H, Mishima, M, Shirakawa, M, Guentert, P, Ito, Y. | Deposit date: | 2018-01-10 | Release date: | 2019-01-23 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | High-Resolution Protein 3D Structure Determination in Living Eukaryotic Cells. Angew.Chem.Int.Ed.Engl., 58, 2019
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2ROG
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![BU of 2rog by Molmil](/molmil-images/mine/2rog) | Solution structure of Thermus thermophilus HB8 TTHA1718 protein in living E. coli cells | Descriptor: | Heavy metal binding protein | Authors: | Sakakibara, D, Sasaki, A, Ikeya, T, Hamatsu, J, Koyama, H, Mishima, M, Mikawa, T, Waelchli, M, Smith, B.O, Shirakawa, M, Guentert, P, Ito, Y. | Deposit date: | 2008-03-21 | Release date: | 2009-03-03 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Protein structure determination in living cells by in-cell NMR spectroscopy Nature, 458, 2009
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