5N2O
Structure Of P63 SAM Domain L514F Mutant Causative Of AEC Syndrome
Summary for 5N2O
| Entry DOI | 10.2210/pdb5n2o/pdb |
| NMR Information | BMRB: 34095 |
| Descriptor | Tumor protein 63 (1 entity in total) |
| Functional Keywords | transcription factor, protein, transcription |
| Biological source | Mus musculus (House Mouse) |
| Total number of polymer chains | 1 |
| Total formula weight | 7957.98 |
| Authors | Rinnenthal, J.,Wuerz, J.M.,Osterburg, C.,Guentert, P.,Doetsch, V. (deposition date: 2017-02-08, release date: 2018-02-07, Last modification date: 2023-06-14) |
| Primary citation | Russo, C.,Osterburg, C.,Sirico, A.,Antonini, D.,Ambrosio, R.,Wurz, J.M.,Rinnenthal, J.,Ferniani, M.,Kehrloesser, S.,Schafer, B.,Guntert, P.,Sinha, S.,Dotsch, V.,Missero, C. Protein aggregation of the p63 transcription factor underlies severe skin fragility in AEC syndrome. Proc. Natl. Acad. Sci. U.S.A., 115:E906-E915, 2018 Cited by PubMed: 29339502DOI: 10.1073/pnas.1713773115 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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