8CRZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8crz by Molmil](/molmil-images/mine/8crz) | |
8CRY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8cry by Molmil](/molmil-images/mine/8cry) | |
8CS0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8cs0 by Molmil](/molmil-images/mine/8cs0) | |
4XO0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4xo0 by Molmil](/molmil-images/mine/4xo0) | |
4XPC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4xpc by Molmil](/molmil-images/mine/4xpc) | |
4XPE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4xpe by Molmil](/molmil-images/mine/4xpe) | |
4XNO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4xno by Molmil](/molmil-images/mine/4xno) | Crystal structure of 5'-CTTATPPPZZZATAAG | Descriptor: | DNA (5'-D(*CP*TP*(BRU)P*AP*TP*(1WA)P*(1WA)P*(1WA)P*(1W5)P*(1W5)P*(1W5)P*AP*TP*AP*AP*G)-3') | Authors: | Georgiadis, M.M, Singh, I. | Deposit date: | 2015-01-15 | Release date: | 2015-05-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.985 Å) | Cite: | Structural basis for a six nucleotide genetic alphabet. J. Am. Chem. Soc., 137, 2015
|
|
1MML
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1mml by Molmil](/molmil-images/mine/1mml) | MECHANISTIC IMPLICATIONS FROM THE STRUCTURE OF A CATALYTIC FRAGMENT OF MMLV REVERSE TRANSCRIPTASE | Descriptor: | MMLV REVERSE TRANSCRIPTASE | Authors: | Georgiadis, M.M, Jessen, S.M, Ogata, C.M, Telesnitsky, A, Goff, S.P, Hendrickson, W.A. | Deposit date: | 1995-07-18 | Release date: | 1995-10-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Mechanistic implications from the structure of a catalytic fragment of Moloney murine leukemia virus reverse transcriptase. Structure, 3, 1995
|
|
2O3H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2o3h by Molmil](/molmil-images/mine/2o3h) | Crystal structure of the human C65A Ape | Descriptor: | ACETATE ION, DNA-(apurinic or apyrimidinic site) lyase, SAMARIUM (III) ION | Authors: | Georgiadis, M.M, Gaur, R.K, Delaplane, S, Svenson, J. | Deposit date: | 2006-12-01 | Release date: | 2007-12-11 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease Mutat.Res., 643, 2008
|
|
2O3C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2o3c by Molmil](/molmil-images/mine/2o3c) | Crystal structure of zebrafish Ape | Descriptor: | APEX nuclease 1, LEAD (II) ION | Authors: | Georgiadis, M.M, Gaur, R.K, Delaplane, S, Svenson, J. | Deposit date: | 2006-12-01 | Release date: | 2007-12-11 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease Mutat.Res., 643, 2008
|
|
7UYO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7uyo by Molmil](/molmil-images/mine/7uyo) | |
7UYN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7uyn by Molmil](/molmil-images/mine/7uyn) | |
7UYP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7uyp by Molmil](/molmil-images/mine/7uyp) | |
7RAC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7rac by Molmil](/molmil-images/mine/7rac) | |
7RAB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7rab by Molmil](/molmil-images/mine/7rab) | |
8DW1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dw1 by Molmil](/molmil-images/mine/8dw1) | Crystal structure of a host-guest complex with 5'-CTTAGTTATAACTAAG-3' | Descriptor: | DNA (5'-D(*CP*TP*TP*AP*GP*TP*TP*A)-3'), DNA (5'-D(P*TP*AP*AP*CP*TP*AP*AP*G)-3'), reverse transcriptase | Authors: | Georgiadis, M.M. | Deposit date: | 2022-07-30 | Release date: | 2023-01-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.849 Å) | Cite: | Two distinct rotations of bithiazole DNA intercalation revealed by direct comparison of crystal structures of Co(III)•bleomycin A 2 and B 2 bound to duplex 5'-TAGTT sites. Bioorg.Med.Chem., 77, 2023
|
|
8DWM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dwm by Molmil](/molmil-images/mine/8dwm) | Host-guest complex of bleomycin A2 fully bound to CTTAGTTATAACTAAG | Descriptor: | BLEOMYCIN A2, COBALT (III) ION, DNA (5'-D(*CP*TP*TP*AP*GP*TP*TP*A)-3'), ... | Authors: | Georgiadis, M.M. | Deposit date: | 2022-08-01 | Release date: | 2023-01-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | Two distinct rotations of bithiazole DNA intercalation revealed by direct comparison of crystal structures of Co(III)•bleomycin A 2 and B 2 bound to duplex 5'-TAGTT sites. Bioorg.Med.Chem., 77, 2023
|
|
8DW8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dw8 by Molmil](/molmil-images/mine/8dw8) | Host-guest structure of BLMA2 partially bound to 5'-ATTAGTTATAACTAAT-3' | Descriptor: | BLEOMYCIN A2, DNA (5'-D(*AP*TP*TP*AP*GP*TP*TP*A)-3'), DNA (5'-D(P*TP*AP*AP*CP*TP*AP*AP*T)-3'), ... | Authors: | Georgiadis, M.M. | Deposit date: | 2022-07-31 | Release date: | 2023-01-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | Two distinct rotations of bithiazole DNA intercalation revealed by direct comparison of crystal structures of Co(III)•bleomycin A 2 and B 2 bound to duplex 5'-TAGTT sites. Bioorg.Med.Chem., 77, 2023
|
|
6MIH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mih by Molmil](/molmil-images/mine/6mih) | Crystal structure of host-guest complex with PC hachimoji DNA | Descriptor: | DNA (5'-D(*CP*TP*TP*AP*(1WA)P*CP*(DB)P*T)-3'), DNA (5'-D(P*AP*(DS)P*GP*(1W5)P*TP*AP*AP*G)-3'), N-terminal fragment of MMLV reverse transcriptase | Authors: | Georgiadis, M.M. | Deposit date: | 2018-09-19 | Release date: | 2019-02-27 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Hachimoji DNA and RNA: A genetic system with eight building blocks. Science, 363, 2019
|
|
6MIG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mig by Molmil](/molmil-images/mine/6mig) | Crystal structure of host-guest complex with PB hachimoji DNA | Descriptor: | DNA (5'-D(*CP*TP*TP*AP*TP*(1WA)P*(1WA)P*(DS))-3'), DNA (5'-D(P*(DB)P*(1W5)P*(1W5)P*AP*TP*AP*AP*G)-3'), Gag-Pol polyprotein | Authors: | Georgiadis, M.M. | Deposit date: | 2018-09-19 | Release date: | 2019-02-27 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Hachimoji DNA and RNA: A genetic system with eight building blocks. Science, 363, 2019
|
|
6MIK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mik by Molmil](/molmil-images/mine/6mik) | Crystal structure of host-guest complex with PP hachimoji DNA | Descriptor: | DNA (5'-D(*CP*TP*TP*AP*TP*(1WA)P*(1WA)P*(DS))-3'), DNA (5'-D(P*(DB)P*(1W5)P*(1W5)P*AP*TP*AP*AP*G)-3'), N-terminal fragment of MMLV reverse transcriptase | Authors: | Georgiadis, M.M. | Deposit date: | 2018-09-19 | Release date: | 2019-02-27 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Hachimoji DNA and RNA: A genetic system with eight building blocks. Science, 363, 2019
|
|
6MKM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mkm by Molmil](/molmil-images/mine/6mkm) | Crystallographic solvent mapping analysis of DMSO/Tris bound to APE1 | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DIMETHYL SULFOXIDE, ... | Authors: | Georgiadis, M.M, He, H, Chen, Q. | Deposit date: | 2018-09-25 | Release date: | 2019-01-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.673 Å) | Cite: | Discovery of Macrocyclic Inhibitors of Apurinic/Apyrimidinic Endonuclease 1. J. Med. Chem., 62, 2019
|
|
6MK3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mk3 by Molmil](/molmil-images/mine/6mk3) | Crystallographic solvent mapping analysis of DMSO bound to APE1 | Descriptor: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, DNA-(apurinic or apyrimidinic site) lyase | Authors: | Georgiadis, M.M, He, H, Chen, Q. | Deposit date: | 2018-09-24 | Release date: | 2019-01-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.478 Å) | Cite: | Discovery of Macrocyclic Inhibitors of Apurinic/Apyrimidinic Endonuclease 1. J. Med. Chem., 62, 2019
|
|
6MKO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mko by Molmil](/molmil-images/mine/6mko) | |
6MKK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6mkk by Molmil](/molmil-images/mine/6mkk) | Crystallographic solvent mapping analysis of DMSO/Mg bound to APE1 | Descriptor: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, DNA-(apurinic or apyrimidinic site) lyase, ... | Authors: | Georgiadis, M.M, He, H, Chen, Q. | Deposit date: | 2018-09-25 | Release date: | 2019-01-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.442 Å) | Cite: | Discovery of Macrocyclic Inhibitors of Apurinic/Apyrimidinic Endonuclease 1. J. Med. Chem., 62, 2019
|
|