8DW1

Crystal structure of a host-guest complex with 5'-CTTAGTTATAACTAAG-3'

Summary for 8DW1

• Entry DOI: 10.2210/pdb8dw1/pdb
• Descriptor: reverse transcriptase, DNA (5'-D(*CP*TP*TP*AP*GP*TP*TP*A)-3'), DNA (5'-D(P*TP*AP*AP*CP*TP*AP*AP*G)-3'), ... (4 entities in total)
• Functional Keywords: host-guest complex dna structure b-form dna moloney murine leukemia virus reverse transcriptase, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Moloney murine leukemia virus; More
• Total number of polymer chains: 3
• Total formula weight: 34874.79

Authors

Georgiadis, M.M. (deposition date: 2022-07-30, release date: 2023-01-11, Last modification date: 2023-10-25)

• Primary citation: Goodwin, K.D.,Lewis, M.A.,Long, E.C.,Georgiadis, M.M.; Two distinct rotations of bithiazole DNA intercalation revealed by direct comparison of crystal structures of Co(III)•bleomycin A 2 and B 2 bound to duplex 5'-TAGTT sites.; Bioorg.Med.Chem., 77:117113-117113, 2023; PubMed: 36516684; DOI: 10.1016/j.bmc.2022.117113

Experimental method

X-RAY DIFFRACTION (1.849 Å)