2F0X
 
 | | Crystal structure and function of human thioesterase superfamily member 2(THEM2) | | Descriptor: | SULFATE ION, Thioesterase superfamily member 2 | | Authors: | Cheng, Z, Song, F, Shan, X, Wang, Y, Wei, Z, Gong, W. | | Deposit date: | 2005-11-14 | | Release date: | 2006-10-10 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of human thioesterase superfamily member 2
Biochem.Biophys.Res.Commun., 349, 2006
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1S2M
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1S4U
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3E20
 | | Crystal structure of S.pombe eRF1/eRF3 complex | | Descriptor: | Eukaryotic peptide chain release factor GTP-binding subunit, Eukaryotic peptide chain release factor subunit 1 | | Authors: | Cheng, Z, Lim, M, Kong, C, Song, H. | | Deposit date: | 2008-08-05 | | Release date: | 2009-05-19 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structural insights into eRF3 and stop codon recognition by eRF1
Genes Dev., 23, 2009
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3E1Y
 | | Crystal structure of human eRF1/eRF3 complex | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, Eukaryotic peptide chain release factor subunit 1 | | Authors: | Cheng, Z, Lim, M, Kong, C, Song, H. | | Deposit date: | 2008-08-05 | | Release date: | 2009-05-19 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Structural insights into eRF3 and stop codon recognition by eRF1
Genes Dev., 23, 2009
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3S8V
 | | Crystal structure of LRP6-Dkk1 complex | | Descriptor: | Dickkopf-related protein 1, Low-density lipoprotein receptor-related protein 6 | | Authors: | Cheng, Z, Xu, W. | | Deposit date: | 2011-05-31 | | Release date: | 2011-10-26 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Crystal structures of the extracellular domain of LRP6 and its complex with DKK1.
Nat.Struct.Mol.Biol., 18, 2011
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3S94
 | | Crystal structure of LRP6-E1E2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Low-density lipoprotein receptor-related protein 6 | | Authors: | Cheng, Z, Xu, W. | | Deposit date: | 2011-05-31 | | Release date: | 2011-11-02 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structures of the extracellular domain of LRP6 and its complex with DKK1.
Nat.Struct.Mol.Biol., 18, 2011
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3S8Z
 | | Crystal structure of LRP6-E3E4 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Low-density lipoprotein receptor-related protein 6 | | Authors: | Cheng, Z, Xu, W. | | Deposit date: | 2011-05-31 | | Release date: | 2011-10-26 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structures of the extracellular domain of LRP6 and its complex with DKK1.
Nat.Struct.Mol.Biol., 18, 2011
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4TN7
 | | Crystal structure of mouse KDM2A-H3K36ME-NO complex | | Descriptor: | FE (III) ION, Lysine-specific demethylase 2A, NITRIC OXIDE, ... | | Authors: | Cheng, Z. | | Deposit date: | 2014-06-03 | | Release date: | 2015-05-13 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
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2GK7
 | | Structural and Functional insights into the human Upf1 helicase core | | Descriptor: | PHOSPHATE ION, Regulator of nonsense transcripts 1 | | Authors: | Cheng, Z, Muhlrad, D, Parker, R, Song, H. | | Deposit date: | 2006-03-31 | | Release date: | 2007-01-09 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural and functional insights into the human Upf1 helicase core
Embo J., 26, 2007
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2I99
 | | Crystal structure of human Mu_crystallin at 2.6 Angstrom | | Descriptor: | Mu-crystallin homolog, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Cheng, Z, Sun, L, He, J, Gong, W. | | Deposit date: | 2006-09-05 | | Release date: | 2007-02-27 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of human {micro}-crystallin complexed with NADPH
Protein Sci., 16, 2007
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2GJK
 | | Structural and functional insights into the human Upf1 helicase core | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Regulator of nonsense transcripts 1 | | Authors: | Cheng, Z, Muhlrad, D, Parker, R, Song, H. | | Deposit date: | 2006-03-31 | | Release date: | 2007-01-09 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural and functional insights into the human Upf1 helicase core
Embo J., 26, 2007
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2GK6
 | | Structural and Functional insights into the human Upf1 helicase core | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | | Authors: | Cheng, Z, Muhlrad, D, Parker, R, Song, H. | | Deposit date: | 2006-03-31 | | Release date: | 2007-01-09 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural and functional insights into the human Upf1 helicase core
Embo J., 26, 2007
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3M6M
 | | Crystal structure of RpfF complexed with REC domain of RpfC | | Descriptor: | 1,2-ETHANEDIOL, IODIDE ION, MAGNESIUM ION, ... | | Authors: | Cheng, Z, Lim, S.C, Qamra, R, Song, H. | | Deposit date: | 2010-03-16 | | Release date: | 2010-09-22 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural Basis of the Sensor-Synthase Interaction in Autoinduction of the Quorum Sensing Signal DSF Biosynthesis
Structure, 18, 2010
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3FHO
 | | Structure of S. pombe Dbp5 | | Descriptor: | ATP-dependent RNA helicase dbp5 | | Authors: | Cheng, Z, Song, H. | | Deposit date: | 2008-12-09 | | Release date: | 2009-10-13 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Solution and crystal structures of mRNA exporter Dbp5p and its interaction with nucleotides
J.Mol.Biol., 388, 2009
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3UTM
 | | Crystal structure of a mouse Tankyrase-Axin complex | | Descriptor: | Axin-1, Tankyrase-1 | | Authors: | Cheng, Z, Morrone, S, Xu, W. | | Deposit date: | 2011-11-26 | | Release date: | 2012-01-18 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of a Tankyrase-Axin complex and its implications for Axin turnover and Tankyrase substrate recruitment.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3M6N
 | | Crystal structure of RpfF | | Descriptor: | RpfF protein | | Authors: | Lim, S.C, Cheng, Z, Qamra, R, Song, H. | | Deposit date: | 2010-03-16 | | Release date: | 2010-09-22 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural Basis of the Sensor-Synthase Interaction in Autoinduction of the Quorum Sensing Signal DSF Biosynthesis
Structure, 18, 2010
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6CQS
 | | Sediminispirochaeta smaragdinae SPS-1 metallo-beta-lactamase | | Descriptor: | Beta-lactamase, ZINC ION | | Authors: | Page, R.C, VanPelt, J, Cheng, Z, Crowder, M.W. | | Deposit date: | 2018-03-16 | | Release date: | 2018-08-29 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | A Noncanonical Metal Center Drives the Activity of the Sediminispirochaeta smaragdinae Metallo-beta-lactamase SPS-1.
Biochemistry, 57, 2018
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6JD7
 | | Crystal structure of anti-CRISPR protein AcrIIC2 dimer | | Descriptor: | ACETATE ION, AcrIIC2, MAGNESIUM ION | | Authors: | Cheng, Z, Huang, X, Sun, W, Wang, Y.L. | | Deposit date: | 2019-01-31 | | Release date: | 2019-05-15 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2.
Nat Commun, 10, 2019
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6JDX
 | | Crystal structure of AcrIIC2 dimer in complex with partial Nme1Cas9 preprocessed with protease alpha-Chymotrypsin | | Descriptor: | 1,2-ETHANEDIOL, AcrIIC2, CRISPR-associated endonuclease Cas9 | | Authors: | Cheng, Z, Huang, X, Sun, W, Wang, Y. | | Deposit date: | 2019-02-02 | | Release date: | 2019-05-15 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2.
Nat Commun, 10, 2019
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6JDJ
 | | Crystal structure of AcrIIC2 dimer in complex with partial Nme1Cas9 | | Descriptor: | AcrIIC2, CRISPR-associated endonuclease Cas9 | | Authors: | Cheng, Z, Huang, X, Sun, W, Wang, Y. | | Deposit date: | 2019-02-01 | | Release date: | 2019-05-15 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2.
Nat Commun, 10, 2019
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5CL1
 | | Complex structure of Norrin with human Frizzled 4 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Frizzled-4, Maltose-binding periplasmic protein,Norrin | | Authors: | Wang, Z, Ke, J, Shen, G, Cheng, Z, Xu, H.E, Xu, W. | | Deposit date: | 2015-07-16 | | Release date: | 2015-08-12 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Structural basis of the Norrin-Frizzled 4 interaction.
Cell Res., 25, 2015
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1FPR
 | | CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN THE CATALYTIC DOMAIN OF SHP-1 AND AN IN VITRO PEPTIDE SUBSTRATE PY469 DERIVED FROM SHPS-1. | | Descriptor: | PEPTIDE PY469, PROTEIN-TYROSINE PHOSPHATASE 1C | | Authors: | Yang, J, Cheng, Z, Niu, Z, Zhao, Z.J, Zhou, G.W. | | Deposit date: | 2000-08-31 | | Release date: | 2001-03-07 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural basis for substrate specificity of protein-tyrosine phosphatase SHP-1.
J.Biol.Chem., 275, 2000
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1T8P
 | | Crystal structure of Human erythrocyte 2,3-bisphosphoglycerate mutase | | Descriptor: | Bisphosphoglycerate mutase | | Authors: | Wang, Y, Wei, Z, Bian, Q, Cheng, Z, Wan, M, Liu, L, Gong, W. | | Deposit date: | 2004-05-13 | | Release date: | 2004-08-10 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of human bisphosphoglycerate mutase
J.Biol.Chem., 279, 2004
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5KF4
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