5V41
 
 | |
5V3W
 | |
5V42
 | |
5V3Y
 | |
5V3Z
 | |
5V3X
 | |
5V40
 | |
7M7V
 | | Crystal Structure of Mtb Pks13 Thioesterase domain in complex with Compound 6 | | Descriptor: | 5-hydroxy-2-(4-hydroxyphenyl)-N-methyl-4-[(2-oxa-6-azaspiro[3.4]octan-6-yl)methyl]-1-benzofuran-3-carboxamide, Polyketide synthase Pks13 | | Authors: | Aggarwal, A, Sacchettini, J.C. | | Deposit date: | 2021-03-29 | | Release date: | 2022-02-16 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical Target.
J.Med.Chem., 65, 2022
|
|
7M5B
 | |
7M5C
 | |
7M5A
 | |
6W32
 | | Crystal structure of Sfh5 | | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, Phosphatidylinositol transfer protein SFH5 | | Authors: | Gulten, G, Khan, D, Aggarwal, A, Krieger, I, Sacchettini, J.C, Bankaitis, V.A. | | Deposit date: | 2020-03-08 | | Release date: | 2020-11-25 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | A Sec14-like phosphatidylinositol transfer protein paralog defines a novel class of heme-binding proteins.
Elife, 9, 2020
|
|
2VU5
 | | Crystal structure of Pndk from Bacillus anthracis | | Descriptor: | NUCLEOSIDE DIPHOSPHATE KINASE | | Authors: | Misra, G, Aggarwal, A, Dube, D, Zaman, M.S, Singh, Y, Ramachandran, R. | | Deposit date: | 2008-05-21 | | Release date: | 2009-03-10 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structure of the Bacillus Anthracis Nucleoside Diphosphate Kinase and its Characterization Reveals an Enzyme Adapted to Perform Under Stress Conditions.
Proteins, 76, 2009
|
|
6UWA
 | | Mouse PKC C1B and C2 domains | | Descriptor: | CITRIC ACID, LEAD (II) ION, Protein kinase C, ... | | Authors: | Aggarwal, A, Mire, J, Sacchettini, J.C, Igumenova, T. | | Deposit date: | 2019-11-04 | | Release date: | 2020-12-09 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Mouse PKC C1B and C2 domains
To Be Published
|
|
2LWE
 | |
2LWD
 | |
1IF1
 | | INTERFERON REGULATORY FACTOR 1 (IRF-1) COMPLEX WITH DNA | | Descriptor: | DNA (26-MER), PROTEIN (INTERFERON REGULATORY FACTOR 1) | | Authors: | Escalante, C.R, Yie, J, Thanos, D, Aggarwal, A. | | Deposit date: | 1997-09-12 | | Release date: | 1998-02-25 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of IRF-1 with bound DNA reveals determinants of interferon regulation.
Nature, 391, 1998
|
|
3SG7
 | | Crystal Structure of GCaMP3-KF(linker 1) | | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | | Authors: | Schreiter, E.R, Akerboom, J, Looger, L.L. | | Deposit date: | 2011-06-14 | | Release date: | 2012-06-20 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Optimization of a GCaMP calcium indicator for neural activity imaging.
J.Neurosci., 32, 2012
|
|
8BON
 | |
3SG5
 | | Crystal Structure of Dimeric GCaMP3-D380Y, QP(linker 1), LP(linker 2) | | Descriptor: | CALCIUM ION, GLYCEROL, Myosin light chain kinase, ... | | Authors: | Schreiter, E.R, Akerboom, J, Looger, L.L. | | Deposit date: | 2011-06-14 | | Release date: | 2012-06-20 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Optimization of a GCaMP calcium indicator for neural activity imaging.
J.Neurosci., 32, 2012
|
|
3SG2
 | | Crystal Structure of GCaMP2-T116V,D381Y | | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | | Authors: | Schreiter, E.R, Akerboom, J, Looger, L.L. | | Deposit date: | 2011-06-14 | | Release date: | 2012-06-20 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Optimization of a GCaMP calcium indicator for neural activity imaging.
J.Neurosci., 32, 2012
|
|
3SG6
 | | Crystal Structure of Dimeric GCaMP2-LIA(linker 1) | | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | | Authors: | Schreiter, E.R, Akerboom, J, Looger, L.L. | | Deposit date: | 2011-06-14 | | Release date: | 2012-06-20 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Optimization of a GCaMP calcium indicator for neural activity imaging.
J.Neurosci., 32, 2012
|
|
3SG3
 | | Crystal Structure of GCaMP3-D380Y | | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | | Authors: | Schreiter, E.R, Akerboom, J, Looger, L.L. | | Deposit date: | 2011-06-14 | | Release date: | 2012-06-20 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Optimization of a GCaMP calcium indicator for neural activity imaging.
J.Neurosci., 32, 2012
|
|
3SG4
 | | Crystal Structure of GCaMP3-D380Y, LP(linker 2) | | Descriptor: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | | Authors: | Schreiter, E.R, Akerboom, J, Looger, L.L. | | Deposit date: | 2011-06-14 | | Release date: | 2012-06-20 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Optimization of a GCaMP calcium indicator for neural activity imaging.
J.Neurosci., 32, 2012
|
|
7E9Y
 | | Crystal structure of eLACCO1 | | Descriptor: | (2S)-2-HYDROXYPROPANOIC ACID, CALCIUM ION, Lactate-binding periplasmic protein TTHA0766,Lactate-binding periplasmic protein TTHA0766 | | Authors: | Wen, Y, Campbell, R.E, Lemieux, M.J, Nasu, Y. | | Deposit date: | 2021-03-05 | | Release date: | 2021-12-22 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | A genetically encoded fluorescent biosensor for extracellular L-lactate.
Nat Commun, 12, 2021
|
|
