1LJ0
 
 | | Structure of quintuple mutant of the rat outer mitocondrial cytochrome b5. | | Descriptor: | Cytochrome B5 outer mitochondrial membrane isoform, MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Cowley, A.B, Altuve, A, Kuchment, O, Terzyan, S, Zhang, X.C, Rivera, M, Benson, D. | | Deposit date: | 2002-04-18 | | Release date: | 2002-11-20 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Toward engineering the stability and hemin binding properties
of microsomal cytochromes b5 into rat outer mitochondrial cytochrome b5:
Examining the influence of residues 25 and 71.
Biochemistry, 41, 2002
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1JVK
 | | THREE-DIMENSIONAL STRUCTURE OF AN IMMUNOGLOBULIN LIGHT CHAIN DIMER ACTING AS A LETHAL AMYLOID PRECURSOR | | Descriptor: | IMMUNOGLOBULIN LAMBDA LIGHT CHAIN | | Authors: | Bourne, P.C, Ramsland, P.A, Shan, L, Fan, Z.-C, DeWitt, C.R, Shultz, B.B, Terzyan, S.S, Edmundson, A.B. | | Deposit date: | 2001-08-30 | | Release date: | 2002-05-03 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Three-dimensional structure of an immunoglobulin light-chain dimer with amyloidogenic properties.
Acta Crystallogr.,Sect.D, 58, 2002
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1KLA
 | | SOLUTION STRUCTURE OF TGF-B1, NMR, MODELS 1-17 OF 33 STRUCTURES | | Descriptor: | TRANSFORMING GROWTH FACTOR-BETA 1 | | Authors: | Hinck, A.P, Archer, S.J, Qian, S.W, Roberts, A.B, Sporn, M.B, Weatherbee, J.A, Tsang, M.L.-S, Lucas, R, Zhang, B.-L, Wenker, J, Torchia, D.A. | | Deposit date: | 1996-01-16 | | Release date: | 1996-08-17 | | Last modified: | 2017-11-29 | | Method: | SOLUTION NMR | | Cite: | Transforming growth factor beta 1: three-dimensional structure in solution and comparison with the X-ray structure of transforming growth factor beta 2.
Biochemistry, 35, 1996
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1KNM
 | | Streptomyces lividans Xylan Binding Domain cbm13 in Complex with Lactose | | Descriptor: | ENDO-1,4-BETA-XYLANASE A, GLYCEROL, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | | Authors: | Notenboom, V, Boraston, A.B, Williams, S.J, Kilburn, D.G, Rose, D.R. | | Deposit date: | 2001-12-19 | | Release date: | 2002-06-19 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | High-resolution crystal structures of the lectin-like xylan binding domain from Streptomyces lividans xylanase 10A with bound substrates reveal a novel mode of xylan binding.
Biochemistry, 41, 2002
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1MFF
 | | MACROPHAGE MIGRATION INHIBITORY FACTOR Y95F MUTANT | | Descriptor: | MACROPHAGE MIGRATION INHIBITORY FACTOR | | Authors: | Taylor, A.B, Stamps, S.L, Wang, S.C, Hackert, M.L, Whitman, C.P. | | Deposit date: | 1998-10-19 | | Release date: | 1999-07-12 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Mechanism of the phenylpyruvate tautomerase activity of macrophage migration inhibitory factor: properties of the P1G, P1A, Y95F, and N97A mutants.
Biochemistry, 39, 2000
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1MFI
 | | CRYSTAL STRUCTURE OF MACROPHAGE MIGRATION INHIBITORY FACTOR COMPLEXED WITH (E)-2-FLUORO-P-HYDROXYCINNAMATE | | Descriptor: | 2-FLUORO-3-(4-HYDROXYPHENYL)-2E-PROPENEOATE, PROTEIN (MACROPHAGE MIGRATION INHIBITORY FACTOR) | | Authors: | Taylor, A.B, Johnson Jr, W.H, Czerwinski, R.M, Whitman, C.P, Hackert, M.L. | | Deposit date: | 1998-08-12 | | Release date: | 1999-06-22 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of macrophage migration inhibitory factor complexed with (E)-2-fluoro-p-hydroxycinnamate at 1.8 A resolution: implications for enzymatic catalysis and inhibition.
Biochemistry, 38, 1999
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2CNJ
 | | NMR studies on the interaction of Insulin-Growth Factor II (IGF-II) with IGF2R domain 11 | | Descriptor: | CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR | | Authors: | Williams, C, Prince, S, Zaccheo, O, Hassan, A.B, Crosby, J, Crump, M. | | Deposit date: | 2006-05-22 | | Release date: | 2007-05-22 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural Insights Into the Interaction of Insulin-Like Growth Factor 2 with Igf2R Domain 11.
Structure, 15, 2007
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1K4T
 | | HUMAN DNA TOPOISOMERASE I (70 KDA) IN COMPLEX WITH THE POISON TOPOTECAN AND COVALENT COMPLEX WITH A 22 BASE PAIR DNA DUPLEX | | Descriptor: | (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE, 2-(1-DIMETHYLAMINOMETHYL-2-HYDROXY-8-HYDROXYMETHYL-9-OXO-9,11-DIHYDRO-INDOLIZINO[1,2-B]QUINOLIN-7-YL)-2-HYDROXY-BUTYRIC ACID, 5'-D(*(TGP)P*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', ... | | Authors: | Staker, B.L, Hjerrild, K, Feese, M.D, Behnke, C.A, Burgin Jr, A.B, Stewart, L.J. | | Deposit date: | 2001-10-08 | | Release date: | 2002-12-04 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The mechanism of topoisomerase I poisoning by a camptothecin analog
Proc.Natl.Acad.Sci.USA, 99, 2002
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1K4S
 | | HUMAN DNA TOPOISOMERASE I IN COVALENT COMPLEX WITH A 22 BASE PAIR DNA DUPLEX | | Descriptor: | 5'-D(*(SPT)P*GP*AP*AP*AP*AP*AP*(5IU)P*(5IU)P*(5IU)P*(5IU)P*T)-3', 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*(5IU)P*(5IU))-3', 5'-D(*AP*AP*AP*AP*AP*TP*(IDO)UP*(IDO)UP*(IDO)UP*(IDO)UP*CP*AP*AP*AP*GP*(IDO)UP*CP*(IDO)UP*(IDO)UP*(IDO)UP*(IDO)UP*T)-3', ... | | Authors: | Staker, B.L, Hjerrild, K, Feese, M.D, Behnke, C.A, Burgin Jr, A.B, Stewart, L.J. | | Deposit date: | 2001-10-08 | | Release date: | 2002-12-04 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | The mechanism of topoisomerase I poisoning by a camptothecin analog
Proc.Natl.Acad.Sci.USA, 99, 2002
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1K8S
 | | BULGED ADENOSINE IN AN RNA DUPLEX | | Descriptor: | 5'-R(*GP*CP*GP*GP*CP*AP*CP*CP*UP*GP*CP*C)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*UP*GP*CP*CP*GP*C)-3' | | Authors: | Thiviyanathan, V, Guliaev, A.B, Leontis, N.B, Gorenstein, D.G. | | Deposit date: | 2001-10-25 | | Release date: | 2001-11-14 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution conformation of a bulged adenosine base in an RNA duplex by relaxation matrix refinement.
J.Mol.Biol., 300, 2000
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1NGX
 | | Chimeric Germline Fab 7g12 with jeffamine fragment bound | | Descriptor: | Germline Metal Chelatase Catalytic Antibody, Heavy chain, Light chain, ... | | Authors: | Yin, J, Andryski, S.E, Beuscher, A.B, Stevens, R.C, Schultz, P.G. | | Deposit date: | 2002-12-18 | | Release date: | 2003-03-18 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural evidence for substrate strain in antibody catalysis
Proc.Natl.Acad.Sci.USA, 100, 2003
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1N7X
 | | HUMAN SERUM TRANSFERRIN, N-LOBE Y45E MUTANT | | Descriptor: | CARBONATE ION, FE (III) ION, Serotransferrin | | Authors: | Adams, T.E, Mason, A.B, He, Q.Y, Halbrooks, P.J, Briggs, S.K, Smith, V.C, Macgillivray, R.T, Everse, S.J. | | Deposit date: | 2002-11-18 | | Release date: | 2003-03-18 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | THE POSITION OF ARGININE 124 CONTROLS THE RATE OF IRON RELEASE FROM THE N-LOBE OF HUMAN SERUM TRANSFERRIN. A STRUCTURAL STUDY
J.Biol.Chem., 278, 2003
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1N7W
 | | Crystal Structure of Human Serum Transferrin, N-Lobe L66W mutant | | Descriptor: | CARBONATE ION, FE (III) ION, Serotransferrin | | Authors: | Adams, T.E, Mason, A.B, He, Q.Y, Halbrooks, P.J, Briggs, S.K, Smith, V.C, MacGillivray, R.T, Everse, S.J. | | Deposit date: | 2002-11-18 | | Release date: | 2003-03-18 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The Position of Arginine 124 Controls the Rate of Iron Release from the N-lobe of Human Serum Transferrin. A Structural Study
J.Biol.Chem., 278, 2003
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1NH3
 | | Human Topoisomerase I Ara-C Complex | | Descriptor: | 5'-D(*(GNG)P*GP*AP*AP*AP*AP*AP*UP*UP*UP*UP*T)-3', 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*UP*(UBB))-3', 5'-D(*AP*AP*AP*AP*AP*TP*UP*UP*UP*UP*CP*(CAR)P*AP*AP*GP*UP*CP*UP*UP*UP*UP*T)-3', ... | | Authors: | Chrencik, J.E, Burgin, A.B, Pommier, Y, Stewart, L, Redinbo, M.R. | | Deposit date: | 2002-12-18 | | Release date: | 2003-03-04 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural Impact of the Leukemia Drug 1-beta-D-Arabinofuranosylcytosine (Ara-C) on the Covalent Human Topoisomerase I-DNA Complex
J.Biol.Chem., 278, 2003
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1N84
 | | HUMAN SERUM TRANSFERRIN, N-LOBE | | Descriptor: | CARBONATE ION, FE (III) ION, Serotransferrin | | Authors: | Adams, T.E, Mason, A.B, He, Q.Y, Halbrooks, P.J, Briggs, S.K, Smith, V.C, Macgillivray, R.T, Everse, S.J. | | Deposit date: | 2002-11-19 | | Release date: | 2003-03-18 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | THE POSITION OF ARGININE 124 CONTROLS THE RATE OF IRON RELEASE FROM THE N-LOBE OF HUMAN SERUM TRANSFERRIN. A STRUCTURAL STUDY
J.Biol.Chem., 278, 2003
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1NAE
 | | Structure of CsCBM6-3 from Clostridium stercorarium in complex with xylotriose | | Descriptor: | CALCIUM ION, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, putative xylanase | | Authors: | Boraston, A.B, Notenboom, V, Warren, R.A.J, Kilburn, D.G, Rose, D.R, Davies, G. | | Deposit date: | 2002-11-27 | | Release date: | 2003-03-18 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structure and ligand binding of carbohydrate-binding module CsCBM6-3 reveals similarities with fucose-specific lectins and "galactose-binding" domains
J.Mol.Biol., 327, 2003
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1NGY
 | | Chimeric Mature Fab 7g12-Apo | | Descriptor: | Mature Metal Chelatase Catalytic Antibody, Heavy chain, Light chain | | Authors: | Yin, J, Andryski, S.A, Beuscher, A.B, Stevens, R.C, Schultz, P.G. | | Deposit date: | 2002-12-18 | | Release date: | 2003-02-04 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural evidence for substrate strain in antibody catalysis
Proc.Natl.Acad.Sci.USA, 100, 2003
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1NGZ
 | | Chimeric Germline Fab 7g12-apo | | Descriptor: | Germline Metal Chelatase Catalytic Antibody, Heavy chain, Light chain | | Authors: | Yin, J, Andryski, S.A, Beuscher, A.B, Stevens, R.C, Schultz, P.G. | | Deposit date: | 2002-12-18 | | Release date: | 2003-02-04 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural evidence for substrate strain in antibody catalysis
Proc.Natl.Acad.Sci.USA, 100, 2003
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2GPV
 | | Estrogen Related Receptor-gamma ligand binding domain complexed with 4-hydroxy-tamoxifen and a SMRT peptide | | Descriptor: | 4-HYDROXYTAMOXIFEN, Estrogen-related receptor gamma, Nuclear receptor corepressor 2 | | Authors: | Wang, L, Zuercher, W.J, Consler, T.G, Lambert, M.H, Miller, A.B, Osband-miller, L.A, McKee, D.D, Willson, T.M, Nolte, R.T. | | Deposit date: | 2006-04-18 | | Release date: | 2006-09-26 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation.
J.Biol.Chem., 281, 2006
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2GI7
 | | Crystal structure of human platelet Glycoprotein VI (GPVI) | | Descriptor: | CHLORIDE ION, GLYCEROL, GPVI protein, ... | | Authors: | Horii, K, Kahn, M.L, Herr, A.B. | | Deposit date: | 2006-03-28 | | Release date: | 2007-04-03 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural basis for platelet collagen responses by the immune-type receptor glycoprotein VI.
Blood, 108, 2006
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2GNU
 | | The crystallization of reaction center from Rhodobacter sphaeroides occurs via a new route | | Descriptor: | BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, CARDIOLIPIN, ... | | Authors: | Wadsten, P, Woehri, A.B, Snijder, A, Katona, G, Gardiner, A.T, Cogdell, R.J, Neutze, R, Engstroem, S. | | Deposit date: | 2006-04-11 | | Release date: | 2006-11-07 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Lipidic sponge phase crystallization of membrane proteins
J.Mol.Biol., 364, 2006
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2GPP
 | | Estrogen Related Receptor-gamma ligand binding domain complexed with a RIP140 peptide and synthetic ligand GSK4716 | | Descriptor: | 4-HYDROXY-N'-(4-ISOPROPYLBENZYL)BENZOHYDRAZIDE, Estrogen-related receptor gamma, Nuclear receptor-interacting protein 1 | | Authors: | Wang, L, Zuercher, W.J, Consler, T.G, Lambert, M.H, Miller, A.B, Osband-miller, L.A, McKee, D.D, Willson, T.M, Nolte, R.T. | | Deposit date: | 2006-04-18 | | Release date: | 2006-09-26 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation.
J.Biol.Chem., 281, 2006
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2GPO
 | | Estrogen Related Receptor-gamma ligand binding domain complexed with a synthetic peptide from RIP140 | | Descriptor: | Estrogen-related receptor gamma, Nuclear receptor-interacting protein 1 | | Authors: | Wang, L, Zuercher, W.J, Consler, T.G, Lambert, M.H, Miller, A.B, Osband-miller, L.A, McKee, D.D, Willson, T.M, Nolte, R.T. | | Deposit date: | 2006-04-18 | | Release date: | 2006-09-26 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation.
J.Biol.Chem., 281, 2006
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2H2N
 | | Crystal structure of human soluble calcium-activated nucleotidase (SCAN) with calcium ion | | Descriptor: | ACETATE ION, CALCIUM ION, Soluble calcium-activated nucleotidase 1 | | Authors: | Yang, M, Horii, K, Herr, A.B, Kirley, T.L. | | Deposit date: | 2006-05-19 | | Release date: | 2006-07-18 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Calcium-dependent dimerization of human soluble calcium activated nucleotidase: characterization of the dimer interface.
J.Biol.Chem., 281, 2006
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2H2U
 | | Crystal structure of the E130Y mutant of human soluble calcium-activated nucleotidase (SCAN) with calcium ion | | Descriptor: | CALCIUM ION, Soluble calcium-activated nucleotidase 1 | | Authors: | Yang, M, Horii, K, Herr, A.B, Kirley, T.L. | | Deposit date: | 2006-05-19 | | Release date: | 2006-07-18 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Calcium-dependent dimerization of human soluble calcium activated nucleotidase: characterization of the dimer interface.
J.Biol.Chem., 281, 2006
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