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2GZF
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BU of 2gzf by Molmil
Crystal structure of the E9 DNase domain with a mutant immunity protein IM9 (Y54F)
Descriptor: Colicin-E9, Colicin-E9 immunity protein, PHOSPHATE ION, ...
Authors:Santi, P.S, Kolade, O.O, Kuhlmann, U.C, Kleanthous, C, Hemmings, A.M.
Deposit date:2006-05-11
Release date:2007-07-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal Structure of the Complex of the Colicin E9 DNase Domain with a Mutant Immunity Protein, IM9 (Y54F)
To be Published
2GZI
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BU of 2gzi by Molmil
Crystal Structure of the E9 DNase Domain with a Mutant Immunity Protein IM9 (V34A)
Descriptor: Colicin-E9, Colicin-E9 immunity protein, PHOSPHATE ION, ...
Authors:Santi, P.S, Kolade, O.O, Kuhlmann, U.C, Kleanthous, C, Hemmings, A.M.
Deposit date:2006-05-11
Release date:2008-03-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of the Complex of the Colicin E9 DNase Domain with a Mutant Immunity Protein, IM9 (V34A)
To be Published
2GZJ
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BU of 2gzj by Molmil
Crystal Structure of the E9 DNase Domain with a Mutant Immunity Protein IM9 (D51A)
Descriptor: Colicin-E9, Colicin-E9 immunity protein, PHOSPHATE ION, ...
Authors:Santi, P.S, Kolade, O.O, Kuhlmann, U.C, Kleanthous, C, Hemmings, A.M.
Deposit date:2006-05-11
Release date:2008-03-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structure of the Complex of the Colicin E9 DNase Domain with a Mutant Immunity Protein, IM9 (D51A)
To be Published
2GZE
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BU of 2gze by Molmil
Crystal structure of the E9 DNase domain with a mutant immunity protein IM9 (Y55A)
Descriptor: Colicin-E9, Colicin-E9 immunity protein, PHOSPHATE ION, ...
Authors:Santi, P.S, Kolade, O.O, Kuhlmann, U.C, Kleanthous, C, Hemmings, A.M.
Deposit date:2006-05-11
Release date:2008-03-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of the Complex of the Colicin E9 DNase Domain with a Mutant Immunity Protein, IM9 (Y55A)
To be Published
1T3O
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BU of 1t3o by Molmil
Solution structure of CsrA, a bacterial carbon storage regulatory protein
Descriptor: Carbon storage regulator
Authors:Koharudin, L.M.I, Georgiou, T, Kleanthous, C, Geoffrey, R, Kaptein, R, Boelens, R.
Deposit date:2004-04-27
Release date:2005-10-18
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A model for RNA binding by the bacterial carbon storage regulatory protein, CsrA
To be Published
1BV1
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BU of 1bv1 by Molmil
BIRCH POLLEN ALLERGEN BET V 1
Descriptor: BET V 1
Authors:Gajhede, M, Osmark, P, Poulsen, F.M, Ipsen, H, Larson, J.N, Joostvan, R.J, Schou, C, Lowenstein, H, Spangfort, M.D.
Deposit date:1997-07-08
Release date:1997-09-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray and NMR structure of Bet v 1, the origin of birch pollen allergy.
Nat.Struct.Biol., 3, 1996
1AYI
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BU of 1ayi by Molmil
COLICIN E7 IMMUNITY PROTEIN IM7
Descriptor: COLICIN E IMMUNITY PROTEIN 7
Authors:Dennis, C.A, Pauptit, R.A, Wallis, R, James, R, Moore, G.R, Kleanthous, C.
Deposit date:1997-11-04
Release date:1998-01-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:A structural comparison of the colicin immunity proteins Im7 and Im9 gives new insights into the molecular determinants of immunity-protein specificity.
Biochem.J., 333 ( Pt 1), 1998
1E0H
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BU of 1e0h by Molmil
Inhibitor Protein Im9 bound to its partner E9 DNase
Descriptor: IMMUNITY PROTEIN FOR COLICIN E9
Authors:Boetzel, R, Czisch, M, Kaptein, R, Hemmings, A.M, James, R, Kleanthous, C, Moore, G.R.
Deposit date:2000-03-28
Release date:2000-10-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR investigation of the interaction of the inhibitor protein Im9 with its partner DNase.
Protein Sci., 9, 2000
1E44
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BU of 1e44 by Molmil
ribonuclease domain of colicin E3 in complex with its immunity protein
Descriptor: 1,2-ETHANEDIOL, COLICIN E3, IMMUNITY PROTEIN
Authors:Carr, S, Walker, D, James, R, Kleanthous, C, Hemmings, A.M.
Deposit date:2000-06-28
Release date:2001-06-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Inhibition of a Ribosome Inactivating Ribonuclease: The Crystal Structure of the Cytotoxic Domain of Colicin E3 in Complex with its Immunity Protein
Structure, 8, 2000
1EMV
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BU of 1emv by Molmil
CRYSTAL STRUCTURE OF COLICIN E9 DNASE DOMAIN WITH ITS COGNATE IMMUNITY PROTEIN IM9 (1.7 ANGSTROMS)
Descriptor: COLICIN E9, IMMUNITY PROTEIN IM9, PHOSPHATE ION
Authors:Kuhlmann, U.C, Pommer, A.J, Moore, G.M, James, R, Kleanthous, C.
Deposit date:2000-03-20
Release date:2000-09-13
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Specificity in protein-protein interactions: the structural basis for dual recognition in endonuclease colicin-immunity protein complexes.
J.Mol.Biol., 301, 2000
2HQS
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BU of 2hqs by Molmil
Crystal structure of TolB/Pal complex
Descriptor: ACETATE ION, GLYCEROL, Peptidoglycan-associated lipoprotein, ...
Authors:Grishkovskaya, I, Bonsor, D.A, Kleanthous, C, Dodson, E.J.
Deposit date:2006-07-19
Release date:2007-04-03
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Molecular mimicry enables competitive recruitment by a natively disordered protein.
J.Am.Chem.Soc., 129, 2007
1BXI
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BU of 1bxi by Molmil
CRYSTAL STRUCTURE OF THE ESCHERICHIA COLI COLICIN E9 DNASE DOMAIN WITH ITS COGNATE IMMUNITY PROTEIN IM9
Descriptor: NICKEL (II) ION, PHOSPHATE ION, PROTEIN (COLICIN E9 IMMUNITY PROTEIN), ...
Authors:Kuhlmann, U.C, Kleanthous, C, James, R, Moore, G.R, Hemmings, A.M.
Deposit date:1998-10-04
Release date:1999-10-04
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal Structure of the E.Coli Colicin E9 DNase Domain With its Cognate Immunity Protein Im9
Thesis, 1998
5XEG
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BU of 5xeg by Molmil
The structure of OsALKBH1
Descriptor: 2-OXOGLUTARIC ACID, MANGANESE (II) ION, Oxidoreductase, ...
Authors:Wang, C, Guo, Y, Zeng, Z.
Deposit date:2017-04-05
Release date:2018-06-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Identification and analysis of adenine N6-methylation sites in the rice genome.
Nat Plants, 4, 2018
5XOI
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BU of 5xoi by Molmil
The structure of OsALKBH1
Descriptor: MANGANESE (II) ION, Oxidoreductase, 2OG-Fe oxygenase family protein, ...
Authors:Wang, C, Guo, Y, Zeng, Z.
Deposit date:2017-05-28
Release date:2018-06-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Identification and analysis of adenine N6-methylation sites in the rice genome.
Nat Plants, 4, 2018
8H8Y
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BU of 8h8y by Molmil
Crystal structure of AbHheG from Acidimicrobiia bacterium
Descriptor: GLYCEROL, alpha/beta hydrolase
Authors:Zhou, C.H, Chen, X, Han, X, Liu, W.D, Wu, Q.Q, Zhu, D.M, Ma, Y.H.
Deposit date:2022-10-24
Release date:2023-08-02
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Flipping the Substrate Creates a Highly Selective Halohydrin Dehalogenase for the Synthesis of Chiral 4-Aryl-2-oxazolidinones from Readily Available Epoxides
Acs Catalysis, 13, 2023
8HQP
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BU of 8hqp by Molmil
Crystal structure of AbHheG mutant from Acidimicrobiia bacterium
Descriptor: AbHheG_m
Authors:Zhou, C.H, Chen, X, Han, X, Liu, W.D, Wu, Q.Q, Zhu, D.M, Ma, Y.H.
Deposit date:2022-12-13
Release date:2023-08-02
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Flipping the Substrate Creates a Highly Selective Halohydrin Dehalogenase for the Synthesis of Chiral 4-Aryl-2-oxazolidinones from Readily Available Epoxides
Acs Catalysis, 13, 2023
2LGW
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BU of 2lgw by Molmil
Solution Structure of the J Domain of HSJ1a
Descriptor: DnaJ homolog subfamily B member 2
Authors:Zhou, C, Gao, X, Cao, C, Hu, H.
Deposit date:2011-08-02
Release date:2012-01-11
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The C-terminal helices of heat shock protein 70 are essential for J-domain binding and ATPase activation.
J.Biol.Chem., 287, 2012
6JZE
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BU of 6jze by Molmil
Crystal structure of VASH2-SVBP complex with the magic triangle I3C
Descriptor: 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 2
Authors:Chen, Z, Ling, Y, Zeyuan, G, Zhu, L.
Deposit date:2019-05-01
Release date:2019-08-07
Last modified:2023-04-05
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer.
Nat Commun, 10, 2019
6JZD
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BU of 6jzd by Molmil
Crystal structure of peptide-bound VASH2-SVBP complex
Descriptor: GLU-GLY-GLU-GLU-TYR, Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 2
Authors:Chen, Z, Ling, Y, Zeyuan, G, Zhu, L.
Deposit date:2019-05-01
Release date:2019-07-17
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.479 Å)
Cite:Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer.
Nat Commun, 10, 2019
6JZC
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BU of 6jzc by Molmil
Structural basis of tubulin detyrosination
Descriptor: GLYCEROL, Small vasohibin-binding protein, Tubulinyl-Tyr carboxypeptidase 2
Authors:Chen, Z, Ling, Y, Zeyuan, G, Zhu, L.
Deposit date:2019-05-01
Release date:2019-07-17
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer.
Nat Commun, 10, 2019
2JNH
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BU of 2jnh by Molmil
Solution Structure of the UBA Domain from Cbl-b
Descriptor: E3 ubiquitin-protein ligase CBL-B
Authors:Zhou, C, Zhou, Z, Lin, D, Hu, H.
Deposit date:2007-01-24
Release date:2008-02-05
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Differential ubiquitin binding of the UBA domains from human c-Cbl and Cbl-b: NMR structural and biochemical insights
Protein Sci., 17, 2008
2LMG
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BU of 2lmg by Molmil
Solution Structure of The C-terminal Domain (537-610) of Human Heat Shock Protein 70
Descriptor: Heat shock 70 kDa protein 1A/1B
Authors:Zhou, C, Gao, X, Wu, M, Hu, H.
Deposit date:2011-12-01
Release date:2012-01-11
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The C-terminal helices of heat shock protein 70 are essential for J-domain binding and ATPase activation.
J.Biol.Chem., 287, 2012
8XGY
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BU of 8xgy by Molmil
Crystal structure of human Golgi resident glutaminyl cyclase in complex with (R,Z)-3-((1H-benzo[d]imidazol-5-yl)methylene)-4-((1-acetylpyrrolidin-3-yl)oxy)indolin-2-one
Descriptor: (3~{Z})-3-(1~{H}-benzimidazol-5-ylmethylidene)-4-[(3~{R})-1-ethanoylpyrrolidin-3-yl]oxy-1~{H}-indol-2-one, Glutaminyl-peptide cyclotransferase, ZINC ION
Authors:Li, G.-B, Wang, X.-Y.
Deposit date:2023-12-16
Release date:2024-06-12
Last modified:2024-06-26
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:X-ray Structure-Guided Discovery of a Potent Benzimidazole Glutaminyl Cyclase Inhibitor That Shows Activity in a Parkinson's Disease Mouse Model.
J.Med.Chem., 67, 2024
8XGT
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BU of 8xgt by Molmil
Crystal structure of human secretory glutaminyl cyclase in complex with (Z)-3-((1H-benzo[d]imidazol-5-yl)methylene)-4-hydroxyindolin-2-one
Descriptor: (3~{Z})-3-(1~{H}-benzimidazol-5-ylmethylidene)-4-oxidanyl-1~{H}-indol-2-one, Glutaminyl-peptide cyclotransferase, ZINC ION
Authors:Li, G.-B, Wang, X.-Y.
Deposit date:2023-12-15
Release date:2024-06-12
Last modified:2024-06-26
Method:X-RAY DIFFRACTION (2.813 Å)
Cite:X-ray Structure-Guided Discovery of a Potent Benzimidazole Glutaminyl Cyclase Inhibitor That Shows Activity in a Parkinson's Disease Mouse Model.
J.Med.Chem., 67, 2024
8XGB
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BU of 8xgb by Molmil
Crystal structure of human secretory glutaminyl cyclase in complex with (S)-1-(1H-benzo[d]imidazol-5-yl)-5-(4-propoxyphenyl)imidazolidin-2-one
Descriptor: (5~{S})-1-(3~{H}-benzimidazol-5-yl)-5-(4-propoxyphenyl)imidazolidin-2-one, Glutaminyl-peptide cyclotransferase, ZINC ION
Authors:Li, G.-B, Wang, X.-Y.
Deposit date:2023-12-15
Release date:2024-06-12
Last modified:2024-06-26
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:X-ray Structure-Guided Discovery of a Potent Benzimidazole Glutaminyl Cyclase Inhibitor That Shows Activity in a Parkinson's Disease Mouse Model.
J.Med.Chem., 67, 2024

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