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4XKG
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BU of 4xkg by Molmil
Crystal structure of hemagglutinin from Taiwan (2013) H6N1 influenza virus in complex with 6'-SLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ...
Authors:Tzarum, N, Zhu, X, Wilson, I.A.
Deposit date:2015-01-11
Release date:2015-04-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure and Receptor Binding of the Hemagglutinin from a Human H6N1 Influenza Virus.
Cell Host Microbe, 17, 2015
4XCF
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BU of 4xcf by Molmil
Crystal structure of human 4E10 Fab in complex with its peptide epitope on HIV-1 gp41; crystals cryoprotected with phosphatidylcholine (03:0 PC)
Descriptor: 4E10 Fab heavy chain, 4E10 Fab light chain, MODIFIED FRAGMENT OF HIV-1 GLYCOPROTEIN (GP41) INCLUDING THE MPER REGION 671-683, ...
Authors:Irimia, A, Stanfield, R.L, Wilson, I.A.
Deposit date:2014-12-17
Release date:2016-02-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.
Immunity, 44, 2016
4XQ5
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BU of 4xq5 by Molmil
Human-infecting H10N8 influenza virus retains strong preference for avian-type receptors
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Tzarum, N, Zhang, H, Zhu, X, Wilson, I.A.
Deposit date:2015-01-19
Release date:2015-04-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.592 Å)
Cite:A Human-Infecting H10N8 Influenza Virus Retains a Strong Preference for Avian-type Receptors.
Cell Host Microbe, 17, 2015
4XQO
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BU of 4xqo by Molmil
Crystal structure of hemagglutinin from Jiangxi-Donghu (2013) H10N8 influenza virus in complex with 6'-SLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Tzarum, N, Zhang, H, Zhu, X, Wilson, I.A.
Deposit date:2015-01-19
Release date:2015-04-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:A Human-Infecting H10N8 Influenza Virus Retains a Strong Preference for Avian-type Receptors.
Cell Host Microbe, 17, 2015
4XBG
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BU of 4xbg by Molmil
Crystal structure of human 4E10 Fab in complex with phosphatidic acid (06:0 PA): 2.73 A resolution
Descriptor: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 4E10 Fab heavy chain, 4E10 Fab light chain, ...
Authors:Irimia, A, Stanfield, R.L, Wilson, I.A.
Deposit date:2014-12-16
Release date:2016-02-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.
Immunity, 44, 2016
3IMV
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BU of 3imv by Molmil
Transthyretin in complex with (E)-4-(4-aminostyryl)-2,6-dibromoaniline
Descriptor: 4-[(E)-2-(4-aminophenyl)ethenyl]-2,6-dibromoaniline, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2009-08-11
Release date:2010-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.
J.Am.Chem.Soc., 132, 2010
4XKD
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BU of 4xkd by Molmil
Crystal structure of hemagglutinin from Taiwan (2013) H6N1 influenza virus
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain
Authors:Tzarum, N, Zhu, X, Wilson, I.A.
Deposit date:2015-01-11
Release date:2015-04-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.482 Å)
Cite:Structure and Receptor Binding of the Hemagglutinin from a Human H6N1 Influenza Virus.
Cell Host Microbe, 17, 2015
4XCC
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BU of 4xcc by Molmil
Crystal structure of human 4E10 Fab crystalized in the presence of Phosphatidylcholine (06:0 PC); I422 space group
Descriptor: 4E10 Fab Heavy chain, 4E10 Fab light chain, GLYCEROL
Authors:Irimia, A, Stanfield, R.L, Wilson, I.A.
Deposit date:2014-12-17
Release date:2016-02-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.
Immunity, 44, 2016
4XC3
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BU of 4xc3 by Molmil
Crystal structure of human 4E10 Fab in complex with its peptide epitope on HIV-1 gp41; crystals cryoprotected with rac-glycerol 1-phosphate
Descriptor: 4E10 Fab heavy chain, 4E10 Fab light chain, MODIFIED FRAGMENT OF HIV-1 GLYCOPROTEIN (GP41) INCLUDING THE MPER REGION 671-683, ...
Authors:Irimia, A, Stanfield, R.L, Wilson, I.A.
Deposit date:2014-12-17
Release date:2016-02-03
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.
Immunity, 44, 2016
4XCY
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BU of 4xcy by Molmil
Crystal structure of human 4E10 Fab in complex with phosphatidylglycerol (06:0 PG)
Descriptor: (2S)-3-{[(R)-{[(2R)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate, 4E10 Fab heavy chain, 4E10 Fab light chain, ...
Authors:Irimia, A, Stanfield, R.L, Wilson, I.A.
Deposit date:2014-12-18
Release date:2016-02-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.96 Å)
Cite:Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.
Immunity, 44, 2016
1NJ9
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BU of 1nj9 by Molmil
Cocaine hydrolytic antibody 15A10
Descriptor: SODIUM ION, immunoglobulin heavy chain, immunoglobulin variable chain
Authors:Larsen, N.A, de Prada, P, Deng, S.X, Zhu, X, Landry, D.W, Wilson, I.A.
Deposit date:2002-12-30
Release date:2004-02-17
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystallographic and biochemical analysis of cocaine-degrading antibody 15A10.
Biochemistry, 43, 2004
3J5M
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BU of 3j5m by Molmil
Cryo-EM structure of the BG505 SOSIP.664 HIV-1 Env trimer with 3 PGV04 Fabs
Descriptor: BG505 SOSIP gp120, BG505 SOSIP gp41, PGV04 heavy chain, ...
Authors:Lyumkis, D, Julien, J.-P, Wilson, I.A, Ward, A.B.
Deposit date:2013-10-26
Release date:2013-11-13
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer.
Science, 342, 2013
4XAW
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BU of 4xaw by Molmil
Crystal structure of human 4E10 Fab in complex with its peptide epitope on HIV-1 gp41: Crystals cryoprotected with phosphatidic acid (08:0 PA)
Descriptor: 4E10 Fab heavy chain, 4E10 Fab light chain, FRAGMENT OF HIV GLYCOPROTEIN (GP41) including the MPER region 671-683, ...
Authors:Irimia, A, Stanfield, R.L, Wilson, I.A.
Deposit date:2014-12-15
Release date:2016-02-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.
Immunity, 44, 2016
4XKE
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BU of 4xke by Molmil
Crystal structure of hemagglutinin from Taiwan (2013) H6N1 influenza virus in complex with 3'-SLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ...
Authors:Tzarum, N, Zhu, X, Wilson, I.A.
Deposit date:2015-01-11
Release date:2015-04-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.356 Å)
Cite:Structure and Receptor Binding of the Hemagglutinin from a Human H6N1 Influenza Virus.
Cell Host Microbe, 17, 2015
4XKF
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BU of 4xkf by Molmil
Crystal structure of hemagglutinin from Taiwan (2013) H6N1 influenza virus in complex with LSTa
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ...
Authors:Tzarum, N, Zhu, X, Wilson, I.A.
Deposit date:2015-01-11
Release date:2015-03-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.446 Å)
Cite:Structure and Receptor Binding of the Hemagglutinin from a Human H6N1 Influenza Virus.
Cell Host Microbe, 17, 2015
4XQU
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BU of 4xqu by Molmil
Crystal structure of hemagglutinin from Jiangxi-Donghu (2013) H10N8 influenza virus in complex with 3'-SLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ...
Authors:Tzarum, N, Zhang, H, Zhu, X, Wilson, I.A.
Deposit date:2015-01-20
Release date:2015-04-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:A Human-Infecting H10N8 Influenza Virus Retains a Strong Preference for Avian-type Receptors.
Cell Host Microbe, 17, 2015
4YAQ
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BU of 4yaq by Molmil
Crystal structure of a computationally optimized PG9 mutant
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, PG9_N100FY Fab heavy chain, ...
Authors:Murrell, S, Julien, J.P, Wilson, I.A.
Deposit date:2015-02-17
Release date:2015-06-03
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth.
J.Clin.Invest., 125, 2015
7TP3
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BU of 7tp3 by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody K288.2
Descriptor: CACODYLATE ION, K288.2 heavy chain, K288.2 light chain, ...
Authors:Yuan, M, Zhu, X, Wilson, I.A.
Deposit date:2022-01-24
Release date:2022-02-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques.
Sci Transl Med, 14, 2022
7TP4
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BU of 7tp4 by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody K398.22
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, K398.22 heavy chain, ...
Authors:Yuan, M, Zhu, X, Wilson, I.A.
Deposit date:2022-01-24
Release date:2022-02-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques.
Sci Transl Med, 14, 2022
7T7B
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BU of 7t7b by Molmil
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with a cross-neutralizing antibody ADI-62113 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ADI-62113 Fab heavy chain, ADI-62113 Fab light chain, ...
Authors:Liu, H, Wilson, I.A.
Deposit date:2021-12-14
Release date:2022-08-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Human antibodies to SARS-CoV-2 with a recurring YYDRxG motif retain binding and neutralization to variants of concern including Omicron.
Commun Biol, 5, 2022
7SJS
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BU of 7sjs by Molmil
Crystal structure of SARS-CoV-2 spike stem helix peptide in complex with neutralizing antibody CC40.8
Descriptor: ACETATE ION, CC40.8 Fab heavy chain, CC40.8 Fab light chain, ...
Authors:Yuan, M, Wilson, I.A.
Deposit date:2021-10-18
Release date:2022-01-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.612 Å)
Cite:A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection.
Sci Transl Med, 14, 2022
3KU3
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BU of 3ku3 by Molmil
Crystal structure of a H2N2 influenza virus hemagglutinin, avian like
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Xu, R, Wilson, I.A.
Deposit date:2009-11-26
Release date:2010-01-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure, receptor binding, and antigenicity of influenza virus hemagglutinins from the 1957 H2N2 pandemic.
J.Virol., 84, 2010
7U8L
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BU of 7u8l by Molmil
Crystal structure of chimeric hemagglutinin cH15/3 in complex with broad protective antibody 31.a.83
Descriptor: Antibody Fab light chain, Hemagglutinin HA1 subunit, Hemagglutinin HA2 subunit, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2022-03-08
Release date:2022-06-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (4.56 Å)
Cite:Influenza chimeric hemagglutinin structures in complex with broadly protective antibodies to the stem and trimer interface.
Proc.Natl.Acad.Sci.USA, 119, 2022
7U8M
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BU of 7u8m by Molmil
Crystal structure of chimeric hemagglutinin cH15/3 in complex with broad protective antibodies 31.a.83 and FluA-20
Descriptor: Antibody 31.a.83 Fab light chain, antibody 31.a.83 Fab heavy chain, antibody FluA-20 Fab heavy chain, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2022-03-08
Release date:2022-06-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (5.39 Å)
Cite:Influenza chimeric hemagglutinin structures in complex with broadly protective antibodies to the stem and trimer interface.
Proc.Natl.Acad.Sci.USA, 119, 2022
7U8J
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BU of 7u8j by Molmil
Crystal structure of chimeric hemagglutinin cH4/3 in complex with broad protective antibody 31.a.83
Descriptor: Antibody Fab light chain, Hemagglutinin HA1 subunit, Hemagglutinin HA2 subunit, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2022-03-08
Release date:2022-06-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (4.9 Å)
Cite:Influenza chimeric hemagglutinin structures in complex with broadly protective antibodies to the stem and trimer interface.
Proc.Natl.Acad.Sci.USA, 119, 2022

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