3GTH
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![BU of 3gth by Molmil](/molmil-images/mine/3gth) | D71G/E101G/M234I mutant in organophosphorus hydrolase from Deinococcus radiodurans | Descriptor: | COBALT (II) ION, FORMIC ACID, Organophosphorus hydrolase | Authors: | Hawwa, R, Larsen, S, Ratia, K, Mesecar, A. | Deposit date: | 2009-03-27 | Release date: | 2009-06-30 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structure-based and random mutagenesis approaches increase the organophosphate-degrading activity of a phosphotriesterase homologue from Deinococcus radiodurans. J.Mol.Biol., 393, 2009
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3GU2
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![BU of 3gu2 by Molmil](/molmil-images/mine/3gu2) | Y97L/G100-/E101- mutant in organophosphorus hydrolase | Descriptor: | COBALT (II) ION, Organophosphorus hydrolase | Authors: | Hawwa, R, Larsen, S, Ratia, K, Mesecar, A. | Deposit date: | 2009-03-28 | Release date: | 2009-06-30 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-based and random mutagenesis approaches increase the organophosphate-degrading activity of a phosphotriesterase homologue from Deinococcus radiodurans. J.Mol.Biol., 393, 2009
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3GU9
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![BU of 3gu9 by Molmil](/molmil-images/mine/3gu9) | R228A mutation in organophosphorus hydrolase from Deinococcus radiodurans | Descriptor: | COBALT (II) ION, Organophosphorus hydrolase | Authors: | Hawwa, R, Larsen, S, Ratia, K, Mesecar, A. | Deposit date: | 2009-03-28 | Release date: | 2009-06-30 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Structure-based and random mutagenesis approaches increase the organophosphate-degrading activity of a phosphotriesterase homologue from Deinococcus radiodurans. J.Mol.Biol., 393, 2009
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3GU1
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![BU of 3gu1 by Molmil](/molmil-images/mine/3gu1) | Y97W mutant in organophosphorus hydrolase from Deinococcus radiodurans | Descriptor: | COBALT (II) ION, GLYCEROL, Organophosphorus hydrolase | Authors: | Hawwa, R, Larsen, S, Ratia, K, Mesecar, A. | Deposit date: | 2009-03-28 | Release date: | 2009-06-30 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-based and random mutagenesis approaches increase the organophosphate-degrading activity of a phosphotriesterase homologue from Deinococcus radiodurans. J.Mol.Biol., 393, 2009
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6CVK
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![BU of 6cvk by Molmil](/molmil-images/mine/6cvk) | |
6CVU
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![BU of 6cvu by Molmil](/molmil-images/mine/6cvu) | Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with cytidine | Descriptor: | 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE, ATP-dependent dethiobiotin synthetase BioD, SULFATE ION | Authors: | Thompson, A.P, Wegener, K.L, Bruning, J.B, Polyak, S.W. | Deposit date: | 2018-03-28 | Release date: | 2018-11-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.426 Å) | Cite: | Mycobacterium tuberculosis Dethiobiotin Synthetase Facilitates Nucleoside Triphosphate Promiscuity through Alternate Binding Modes Acs Catalysis, 8(11), 2018
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3GAB
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![BU of 3gab by Molmil](/molmil-images/mine/3gab) | C-terminal domain of Bacillus subtilis MutL crystal form I | Descriptor: | DNA mismatch repair protein mutL | Authors: | Guarne, A, Pillon, M.C, Lorenowicz, J.J, Mitchell, R.R, Chung, Y.S, Friedhoff, P. | Deposit date: | 2009-02-17 | Release date: | 2010-07-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the endonuclease domain of MutL: unlicensed to cut. Mol.Cell, 39, 2010
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6CWD
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![BU of 6cwd by Molmil](/molmil-images/mine/6cwd) | |
3GK1
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![BU of 3gk1 by Molmil](/molmil-images/mine/3gk1) | X-ray structure of bovine SBi132,Ca(2+)-S100B | Descriptor: | 2-[(5-hex-1-yn-1-ylfuran-2-yl)carbonyl]-N-methylhydrazinecarbothioamide, CACODYLATE ION, CALCIUM ION, ... | Authors: | Charpentier, T.H, Weber, D.J, Toth, E.A. | Deposit date: | 2009-03-09 | Release date: | 2009-06-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Small molecules bound to unique sites in the target protein binding cleft of calcium-bound S100B as characterized by nuclear magnetic resonance and X-ray crystallography. Biochemistry, 48, 2009
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3GK2
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![BU of 3gk2 by Molmil](/molmil-images/mine/3gk2) | X-ray structure of bovine SBi279,Ca(2+)-S100B | Descriptor: | (Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide, CACODYLATE ION, CALCIUM ION, ... | Authors: | Charpentier, T.H, Weber, D.J, Toth, E.A. | Deposit date: | 2009-03-09 | Release date: | 2009-06-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.984 Å) | Cite: | Small molecules bound to unique sites in the target protein binding cleft of calcium-bound S100B as characterized by nuclear magnetic resonance and X-ray crystallography. Biochemistry, 48, 2009
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3GK4
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![BU of 3gk4 by Molmil](/molmil-images/mine/3gk4) | X-ray structure of bovine SBi523,Ca(2+)-S100B | Descriptor: | CALCIUM ION, Protein S100-B, ethyl 5-{[(1R)-1-(ethoxycarbonyl)-2-oxopropyl]sulfanyl}-1,2-dihydro[1,2,3]triazolo[1,5-a]quinazoline-3-carboxylate | Authors: | Charpentier, T.H, Weber, D.J, Toth, E.A. | Deposit date: | 2009-03-09 | Release date: | 2009-06-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Small molecules bound to unique sites in the target protein binding cleft of calcium-bound S100B as characterized by nuclear magnetic resonance and X-ray crystallography. Biochemistry, 48, 2009
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6CIX
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![BU of 6cix by Molmil](/molmil-images/mine/6cix) | |
6CEJ
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![BU of 6cej by Molmil](/molmil-images/mine/6cej) | |
3F4C
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![BU of 3f4c by Molmil](/molmil-images/mine/3f4c) | Crystal structure of organophosphorus hydrolase from Geobacillus stearothermophilus strain 10, with glycerol bound | Descriptor: | COBALT (II) ION, GLYCEROL, Organophosphorus hydrolase | Authors: | Hawwa, R, Aikens, J, Turner, R.J, Santarsiero, B, Mesecar, A. | Deposit date: | 2008-10-31 | Release date: | 2009-09-15 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Structural basis for thermostability revealed through the identification and characterization of a highly thermostable phosphotriesterase-like lactonase from Geobacillus stearothermophilus. Arch.Biochem.Biophys., 488, 2009
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4ALV
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![BU of 4alv by Molmil](/molmil-images/mine/4alv) | Benzofuropyrimidinone Inhibitors of Pim-1 | Descriptor: | 8-bromo-2-{2-chloro-4-[(piperidin-4-ylmethyl)amino]phenyl}[1]benzofuro[3,2-d]pyrimidin-4(3H)-one, IMIDAZOLE, SERINE/THREONINE-PROTEIN KINASE PIM-1 | Authors: | Stout, T.J, Adams, L. | Deposit date: | 2012-03-05 | Release date: | 2013-01-16 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | The Design, Synthesis, and Biological Evaluation of Pim Kinase Inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
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3GX2
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![BU of 3gx2 by Molmil](/molmil-images/mine/3gx2) | |
3E33
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![BU of 3e33 by Molmil](/molmil-images/mine/3e33) | Protein farnesyltransferase complexed with FPP and ethylenediamine scaffold inhibitor 7 | Descriptor: | FARNESYL DIPHOSPHATE, N-benzyl-N-(2-{(4-cyanophenyl)[(1-methyl-1H-imidazol-5-yl)methyl]amino}ethyl)-2-methylbenzenesulfonamide, Protein farnesyltransferase subunit beta, ... | Authors: | Hast, M.A, Beese, L.S. | Deposit date: | 2008-08-06 | Release date: | 2009-03-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for binding and selectivity of antimalarial and anticancer ethylenediamine inhibitors to protein farnesyltransferase. Chem.Biol., 16, 2009
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3WBN
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![BU of 3wbn by Molmil](/molmil-images/mine/3wbn) | Crystal structure of MATE in complex with MaL6 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, MaL6, Putative uncharacterized protein | Authors: | Tanaka, Y, Ishitani, R, Nureki, O. | Deposit date: | 2013-05-20 | Release date: | 2013-06-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structural basis for the drug extrusion mechanism by a MATE multidrug transporter. Nature, 496, 2013
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3E34
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![BU of 3e34 by Molmil](/molmil-images/mine/3e34) | Protein farnesyltransferase complexed with FPP and ethylenediamine-scaffold inhibitor 10 | Descriptor: | 3-{2'-[{[1-(tert-butoxycarbonyl)piperidin-4-yl]methyl}(2-{(4-cyanophenyl)[(1-methyl-1H-imidazol-5-yl)methyl]amino}ethyl)sulfamoyl]biphenyl-3-yl}propanoic acid, FARNESYL DIPHOSPHATE, Protein farnesyltransferase subunit beta, ... | Authors: | Hast, M.A, Beese, L.S. | Deposit date: | 2008-08-06 | Release date: | 2009-03-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural basis for binding and selectivity of antimalarial and anticancer ethylenediamine inhibitors to protein farnesyltransferase. Chem.Biol., 16, 2009
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3GX6
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![BU of 3gx6 by Molmil](/molmil-images/mine/3gx6) | |
3WO6
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![BU of 3wo6 by Molmil](/molmil-images/mine/3wo6) | Crystal structure of YidC from Bacillus halodurans (form I) | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CADMIUM ION, Membrane protein insertase YidC 2 | Authors: | Kumazaki, K, Tsukazaki, T, Ishitani, R, Nureki, O. | Deposit date: | 2013-12-20 | Release date: | 2014-04-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.403 Å) | Cite: | Structural basis of Sec-independent membrane protein insertion by YidC. Nature, 509, 2014
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3WOZ
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![BU of 3woz by Molmil](/molmil-images/mine/3woz) | Crystal structure of CLASP2 TOG domain (TOG3) | Descriptor: | CLIP-associating protein 2 | Authors: | Hayashi, I, Maki, T. | Deposit date: | 2014-01-06 | Release date: | 2015-05-27 | Last modified: | 2018-10-17 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | CLASP2 Has Two Distinct TOG Domains That Contribute Differently to Microtubule Dynamics J. Mol. Biol., 427, 2015
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3W4T
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![BU of 3w4t by Molmil](/molmil-images/mine/3w4t) | Crystal structure of MATE P26A mutant | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Putative uncharacterized protein | Authors: | Tanaka, Y, Ishitani, R, Nureki, O. | Deposit date: | 2013-01-16 | Release date: | 2013-04-03 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.096 Å) | Cite: | Structural basis for the drug extrusion mechanism by a MATE multidrug transporter. Nature, 496, 2013
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3GX5
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![BU of 3gx5 by Molmil](/molmil-images/mine/3gx5) | |
3GTX
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![BU of 3gtx by Molmil](/molmil-images/mine/3gtx) | D71G/E101G mutant in organophosphorus hydrolase from Deinococcus radiodurans | Descriptor: | COBALT (II) ION, Organophosphorus hydrolase | Authors: | Hawwa, R, Larsen, S, Ratia, K, Mesecar, A. | Deposit date: | 2009-03-28 | Release date: | 2009-06-30 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Structure-based and random mutagenesis approaches increase the organophosphate-degrading activity of a phosphotriesterase homologue from Deinococcus radiodurans. J.Mol.Biol., 393, 2009
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