2KBJ
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![BU of 2kbj by Molmil](/molmil-images/mine/2kbj) | solution structure of BmKalphaTx11 (minor conformation) | Descriptor: | Toxin Bmka2 | Authors: | Zhu, J, Wu, H. | Deposit date: | 2008-11-28 | Release date: | 2009-12-08 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Solution structure of BmKalphaTx11, a toxin from the venom of the Chinese scorpion Buthus martensii Karsch Biochem.Biophys.Res.Commun., 391, 2010
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2KBH
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![BU of 2kbh by Molmil](/molmil-images/mine/2kbh) | solution structure of BmKalphaTx11 (major conformation) | Descriptor: | Toxin Bmka2 | Authors: | Zhu, J, Wu, H. | Deposit date: | 2008-11-28 | Release date: | 2009-12-08 | Last modified: | 2019-12-11 | Method: | SOLUTION NMR | Cite: | Solution structure of BmKalphaTx11, a toxin from the venom of the Chinese scorpion Buthus martensii Karsch Biochem.Biophys.Res.Commun., 391, 2010
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2I0N
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![BU of 2i0n by Molmil](/molmil-images/mine/2i0n) | Structure of Dictyostelium discoideum Myosin VII SH3 domain with adjacent proline rich region | Descriptor: | Class VII unconventional myosin | Authors: | Wang, Q, Deloia, M.A, Kang, Y, Litchke, C, Titus, M.A, Walters, K.J. | Deposit date: | 2006-08-10 | Release date: | 2007-01-09 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | The SH3 domain of a M7 interacts with its C-terminal proline-rich region. Protein Sci., 16, 2007
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4QR5
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![BU of 4qr5 by Molmil](/molmil-images/mine/4qr5) | Brd4 Bromodomain 1 complex with its novel inhibitors | Descriptor: | Bromodomain-containing protein 4, N-[3-(cyclopentylsulfamoyl)-5-(2-oxo-2,3-dihydro-1,3-thiazol-4-yl)phenyl]cyclopropanecarboxamide | Authors: | Xiong, B, Cao, D.Y, Chen, T.T, Xu, Y.C. | Deposit date: | 2014-06-30 | Release date: | 2015-07-01 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.41 Å) | Cite: | Fragment-based drug discovery of 2-thiazolidinones as BRD4 inhibitors: 2. Structure-based optimization J.Med.Chem., 58, 2015
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4QR3
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![BU of 4qr3 by Molmil](/molmil-images/mine/4qr3) | Brd4 Bromodomain 1 complex with its novel inhibitors | Descriptor: | Bromodomain-containing protein 4, N-cyclopentyl-3-(2-oxo-2,3-dihydro-1,3-thiazol-4-yl)benzenesulfonamide | Authors: | Xiong, B, Cao, D.Y, Chen, T.T, Xu, Y.C. | Deposit date: | 2014-06-30 | Release date: | 2015-07-01 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.374 Å) | Cite: | Fragment-based drug discovery of 2-thiazolidinones as BRD4 inhibitors: 2. Structure-based optimization J.Med.Chem., 58, 2015
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4QR4
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![BU of 4qr4 by Molmil](/molmil-images/mine/4qr4) | Brd4 Bromodomain 1 complex with its novel inhibitors | Descriptor: | 2-chloro-N-cyclopentyl-5-(2-oxo-2,3-dihydro-1,3-thiazol-4-yl)benzenesulfonamide, Bromodomain-containing protein 4 | Authors: | Xiong, B, Cao, D.Y, Chen, T.T, Xu, Y.C. | Deposit date: | 2014-06-30 | Release date: | 2015-07-01 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | Fragment-based drug discovery of 2-thiazolidinones as BRD4 inhibitors: 2. Structure-based optimization J.Med.Chem., 58, 2015
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4TTR
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![BU of 4ttr by Molmil](/molmil-images/mine/4ttr) | |
4TTQ
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![BU of 4ttq by Molmil](/molmil-images/mine/4ttq) | |
4TTP
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![BU of 4ttp by Molmil](/molmil-images/mine/4ttp) | |
6A0Q
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![BU of 6a0q by Molmil](/molmil-images/mine/6a0q) | The crystal structure of Lpg2622_E64 complex | Descriptor: | Lpg2622, N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE | Authors: | Gong, X, Ge, H. | Deposit date: | 2018-06-06 | Release date: | 2018-09-12 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural characterization of the hypothetical protein Lpg2622, a new member of the C1 family peptidases from Legionella pneumophila FEBS Lett., 592, 2018
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6A0N
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![BU of 6a0n by Molmil](/molmil-images/mine/6a0n) | The crystal structure of apo-Lpg2622 | Descriptor: | Lpg2622 | Authors: | Gong, X, Ge, H. | Deposit date: | 2018-06-05 | Release date: | 2018-09-12 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural characterization of the hypothetical protein Lpg2622, a new member of the C1 family peptidases from Legionella pneumophila FEBS Lett., 592, 2018
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2AST
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![BU of 2ast by Molmil](/molmil-images/mine/2ast) | Crystal structure of Skp1-Skp2-Cks1 in complex with a p27 peptide | Descriptor: | BENZAMIDINE, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinases regulatory subunit 1, ... | Authors: | Hao, B, Zhang, N, Schulman, B.A, Wu, G, Pagano, M, Pavletich, N.P. | Deposit date: | 2005-08-24 | Release date: | 2005-10-18 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Basis of the Cks1-Dependent Recognition of p27(Kip1) by the SCF(Skp2) Ubiquitin Ligase. Mol.Cell, 20, 2005
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6UPL
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![BU of 6upl by Molmil](/molmil-images/mine/6upl) | Structure of FACT_subnucleosome complex 2 | Descriptor: | DNA (79-mer), FACT complex subunit SPT16, FACT complex subunit SSRP1, ... | Authors: | Zhou, K, Tan, Y.Z, Wei, H, Liu, Y, Carragher, B, Potter, C, Luger, K. | Deposit date: | 2019-10-17 | Release date: | 2019-12-11 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (7.4 Å) | Cite: | FACT caught in the act of manipulating the nucleosome. Nature, 577, 2020
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6UPK
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![BU of 6upk by Molmil](/molmil-images/mine/6upk) | Structure of FACT_subnucleosome complex 1 | Descriptor: | DNA (79-mer), FACT complex subunit SPT16, FACT complex subunit SSRP1, ... | Authors: | Zhou, K, Tan, Y.Z, Wei, H, Liu, Y, Carragher, B, Potter, C, Luger, K. | Deposit date: | 2019-10-17 | Release date: | 2019-12-11 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | FACT caught in the act of manipulating the nucleosome. Nature, 577, 2020
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7CQQ
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![BU of 7cqq by Molmil](/molmil-images/mine/7cqq) | GmaS in complex with AMPPNP and MetSox | Descriptor: | (2S)-2-AMINO-4-(METHYLSULFONIMIDOYL)BUTANOIC ACID, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Li, C.Y, Zhang, Y.Z. | Deposit date: | 2020-08-11 | Release date: | 2020-11-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.295 Å) | Cite: | Crystal structures of gamma-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine. J.Biol.Chem., 296, 2020
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7CQL
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![BU of 7cql by Molmil](/molmil-images/mine/7cql) | Apo GmaS without ligand | Descriptor: | Type III glutamate--ammonia ligase | Authors: | Li, C.Y, Zhang, Y.Z. | Deposit date: | 2020-08-11 | Release date: | 2020-11-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.801 Å) | Cite: | Crystal structures of gamma-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine. J.Biol.Chem., 296, 2020
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7CQN
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![BU of 7cqn by Molmil](/molmil-images/mine/7cqn) | GmaS in complex with AMPPCP | Descriptor: | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Type III glutamate--ammonia ligase | Authors: | Li, C.Y, Zhang, Y.Z. | Deposit date: | 2020-08-11 | Release date: | 2020-11-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.962 Å) | Cite: | Crystal structures of gamma-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine. J.Biol.Chem., 296, 2020
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7CQU
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![BU of 7cqu by Molmil](/molmil-images/mine/7cqu) | GmaS/ADP/MetSox-P complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, L-METHIONINE-S-SULFOXIMINE PHOSPHATE, MAGNESIUM ION, ... | Authors: | Li, C.Y, Zhang, Y.Z. | Deposit date: | 2020-08-11 | Release date: | 2020-11-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Crystal structures of gamma-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine. J.Biol.Chem., 296, 2020
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7CQX
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![BU of 7cqx by Molmil](/molmil-images/mine/7cqx) | GmaS/ADP complex-Conformation 2 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Type III glutamate--ammonia ligase | Authors: | Li, C.Y, Zhang, Y.Z. | Deposit date: | 2020-08-11 | Release date: | 2020-11-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Crystal structures of gamma-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine. J.Biol.Chem., 296, 2020
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7CQW
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![BU of 7cqw by Molmil](/molmil-images/mine/7cqw) | GmaS/ADP complex-Conformation 1 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Type III glutamate--ammonia ligase | Authors: | Li, C.Y, Zhang, Y.Z. | Deposit date: | 2020-08-11 | Release date: | 2020-11-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.297 Å) | Cite: | Crystal structures of gamma-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine. J.Biol.Chem., 296, 2020
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8Y74
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4HXN
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![BU of 4hxn by Molmil](/molmil-images/mine/4hxn) | Brd4 Bromodomain 1 complex with 4-(2-FLUOROPHENYL)-1,3-THIAZOL-2(3H)-ONE inhibitor | Descriptor: | 4-(2-fluorophenyl)-1,3-thiazol-2(3H)-one, Bromodomain-containing protein 4 | Authors: | Chen, T.T, Cao, D.Y, Chen, W.Y, Xiong, B, Shen, J.K, Xu, Y.C. | Deposit date: | 2012-11-12 | Release date: | 2013-04-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Fragment-Based Drug Discovery of 2-Thiazolidinones as Inhibitors of the Histone Reader BRD4 Bromodomain. J.Med.Chem., 56, 2013
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4HXK
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![BU of 4hxk by Molmil](/molmil-images/mine/4hxk) | Brd4 Bromodomain 1 complex with 6,7-DIHYDROTHIENO[3,2-C]PYRIDIN-5(4H)-YL(1H-IMIDAZOL-1-YL)METHANONE inhibitor | Descriptor: | 6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl(1H-imidazol-1-yl)methanone, Bromodomain-containing protein 4 | Authors: | Chen, T.T, Cao, D.Y, Chen, W.Y, Xiong, B, Shen, J.K, Xu, Y.C. | Deposit date: | 2012-11-12 | Release date: | 2013-04-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Fragment-Based Drug Discovery of 2-Thiazolidinones as Inhibitors of the Histone Reader BRD4 Bromodomain. J.Med.Chem., 56, 2013
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4HXR
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![BU of 4hxr by Molmil](/molmil-images/mine/4hxr) | Brd4 Bromodomain 1 complex with N-[3-(2-OXO-2,3-DIHYDRO-1,3-THIAZOL-4-YL)PHENYL]THIOPHENE-2-SULFONAMIDE inhibitor | Descriptor: | Bromodomain-containing protein 4, N-[3-(2-oxo-2,3-dihydro-1,3-thiazol-4-yl)phenyl]thiophene-2-sulfonamide | Authors: | Chen, T.T, Cao, D.Y, Chen, W.Y, Xiong, B, Shen, J.K, Xu, Y.C. | Deposit date: | 2012-11-12 | Release date: | 2013-04-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Fragment-Based Drug Discovery of 2-Thiazolidinones as Inhibitors of the Histone Reader BRD4 Bromodomain. J.Med.Chem., 56, 2013
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4HXS
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![BU of 4hxs by Molmil](/molmil-images/mine/4hxs) | Brd4 Bromodomain 1 complex with N-[3-(2-OXO-2,3-DIHYDRO-1,3-THIAZOL-4-YL)PHENYL]-1-PHENYLMETHANESULFONAMIDE inhibitor | Descriptor: | Bromodomain-containing protein 4, N-[3-(2-oxo-2,3-dihydro-1,3-thiazol-4-yl)phenyl]-1-phenylmethanesulfonamide | Authors: | Chen, T.T, Cao, D.Y, Chen, W.Y, Xiong, B, Shen, J.K, Xu, Y.C. | Deposit date: | 2012-11-12 | Release date: | 2013-04-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Fragment-Based Drug Discovery of 2-Thiazolidinones as Inhibitors of the Histone Reader BRD4 Bromodomain. J.Med.Chem., 56, 2013
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