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3T05
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BU of 3t05 by Molmil
Crystal structure of S. aureus Pyruvate Kinase
Descriptor: PHOSPHATE ION, Pyruvate kinase
Authors:Worrall, L.J, Vuckovic, M, Strynadka, N.C.J.
Deposit date:2011-07-19
Release date:2011-10-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Methicillin-resistant Staphylococcus aureus (MRSA) pyruvate kinase as a target for bis-indole alkaloids with antibacterial activities.
J.Biol.Chem., 286, 2011
3VZL
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Crystal structure of the Bacillus circulans endo-beta-(1,4)-xylanase (BcX) N35H mutant
Descriptor: Endo-1,4-beta-xylanase, SULFATE ION
Authors:Ludwiczek, M.L, D'Angelo, I, Yalloway, G.N, Okon, M, Nielsen, J.E, Strynadka, N.C, Withers, S.G, McIntosh, L.P.
Deposit date:2012-10-15
Release date:2013-05-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Strategies for modulating the pH-dependent activity of a family 11 glycoside hydrolase
Biochemistry, 52, 2013
3VZN
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Crystal structure of the Bacillus circulans endo-beta-(1,4)-xylanase (BcX) N35E mutant with Glu78 covalently bonded to 2-deoxy-2-fluoro-xylobiose
Descriptor: Endo-1,4-beta-xylanase, SULFATE ION, beta-D-xylopyranose-(1-4)-1,5-anhydro-2-deoxy-2-fluoro-D-xylitol
Authors:Ludwiczek, M.L, D'Angelo, I, Yalloway, G.N, Okon, M, Nielsen, J.E, Strynadka, N.C, Withers, S.G, McIntosh, L.P.
Deposit date:2012-10-15
Release date:2013-05-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Strategies for modulating the pH-dependent activity of a family 11 glycoside hydrolase
Biochemistry, 52, 2013
3VZM
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Crystal structure of the Bacillus circulans endo-beta-(1,4)-xylanase (BcX) E172H mutant with Glu78 covalently bonded to 2-deoxy-2-fluoro-xylobiose
Descriptor: Endo-1,4-beta-xylanase, beta-D-xylopyranose-(1-4)-1,5-anhydro-2-deoxy-2-fluoro-D-xylitol
Authors:Ludwiczek, M.L, D'Angelo, I, Yalloway, G.N, Okon, M, Nielsen, J.E, Strynadka, N.C, Withers, S.G, McIntosh, L.P.
Deposit date:2012-10-15
Release date:2013-05-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Strategies for modulating the pH-dependent activity of a family 11 glycoside hydrolase
Biochemistry, 52, 2013
3VZJ
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BU of 3vzj by Molmil
Crystal structure of the Bacillus circulans endo-beta-(1,4)-xylanase (BcX) E172H mutant
Descriptor: Endo-1,4-beta-xylanase, SULFATE ION
Authors:Ludwiczek, M.L, D'Angelo, I, Yalloway, G.N, Okon, M, Nielsen, J.E, Strynadka, N.C, Withers, S.G, McIntosh, L.P.
Deposit date:2012-10-14
Release date:2013-05-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.406 Å)
Cite:Strategies for modulating the pH-dependent activity of a family 11 glycoside hydrolase
Biochemistry, 52, 2013
3VZO
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BU of 3vzo by Molmil
Crystal structure of the Bacillus circulans endo-beta-(1,4)-xylanase (BcX) N35H mutant with Glu78 covalently bonded to 2-deoxy-2-fluoro-xylobiose
Descriptor: Endo-1,4-beta-xylanase, SULFATE ION, beta-D-xylopyranose-(1-4)-1,5-anhydro-2-deoxy-2-fluoro-D-xylitol
Authors:Ludwiczek, M.L, D'Angelo, I, Yalloway, G.N, Okon, M, Nielsen, J.E, Strynadka, N.C, Withers, S.G, McIntosh, L.P.
Deposit date:2012-10-15
Release date:2013-05-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Strategies for modulating the pH-dependent activity of a family 11 glycoside hydrolase
Biochemistry, 52, 2013
3VZK
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BU of 3vzk by Molmil
Crystal structure of the Bacillus circulans endo-beta-(1,4)-xylanase (BcX) N35E mutant
Descriptor: Endo-1,4-beta-xylanase, SULFATE ION
Authors:Ludwiczek, M.L, D'Angelo, I, Yalloway, G.N, Okon, M, Nielsen, J.E, Strynadka, N.C, Withers, S.G, McIntosh, L.P.
Deposit date:2012-10-14
Release date:2013-05-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Strategies for modulating the pH-dependent activity of a family 11 glycoside hydrolase
Biochemistry, 52, 2013
1F6D
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BU of 1f6d by Molmil
THE STRUCTURE OF UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE FROM E. COLI.
Descriptor: CHLORIDE ION, SODIUM ION, UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE, ...
Authors:Campbell, R.E, Mosimann, S.C, Tanner, M.E, Strynadka, N.C.J.
Deposit date:2000-06-21
Release date:2000-12-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structure of UDP-N-acetylglucosamine 2-epimerase reveals homology to phosphoglycosyl transferases.
Biochemistry, 39, 2000
3T0T
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BU of 3t0t by Molmil
Crystal structure of S. aureus Pyruvate Kinase
Descriptor: N'-[(1E)-1-(1H-benzimidazol-2-yl)ethylidene]-5-bromo-2-hydroxybenzohydrazide, PHOSPHATE ION, Pyruvate kinase
Authors:Worrall, L.J, Vuckovic, M, Strynadka, N.C.J.
Deposit date:2011-07-20
Release date:2012-06-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Cheminformatics-driven discovery of selective, nanomolar inhibitors for staphylococcal pyruvate kinase.
Acs Chem.Biol., 7, 2012
1XA1
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Crystal structure of the sensor domain of BlaR1 from Staphylococcus aureus in its apo form
Descriptor: PHOSPHATE ION, PYROPHOSPHATE 2-, Regulatory protein blaR1
Authors:Wilke, M.S, Hills, T.L, Zhang, H.Z, Chambers, H.F, Strynadka, N.C.
Deposit date:2004-08-24
Release date:2004-09-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of the Apo and penicillin-acylated forms of the BlaR1 beta-lactam sensor of Staphylococcus aureus.
J.Biol.Chem., 279, 2004
1G9R
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BU of 1g9r by Molmil
CRYSTAL STRUCTURE OF GALACTOSYLTRANSFERASE LGTC IN COMPLEX WITH MN AND UDP-2F-GALACTOSE
Descriptor: ACETIC ACID, GLYCOSYL TRANSFERASE, MANGANESE (II) ION, ...
Authors:Persson, K, Hoa, D.L, Diekelmann, M, Wakarchuk, W.W, Withers, S.G, Strynadka, N.C.J.
Deposit date:2000-11-27
Release date:2001-02-14
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the retaining galactosyltransferase LgtC from Neisseria meningitidis in complex with donor and acceptor sugar analogs.
Nat.Struct.Biol., 8, 2001
1GA8
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BU of 1ga8 by Molmil
CRYSTAL STRUCTURE OF GALACOSYLTRANSFERASE LGTC IN COMPLEX WITH DONOR AND ACCEPTOR SUGAR ANALOGS.
Descriptor: 4-deoxy-beta-D-xylo-hexopyranose-(1-4)-beta-D-glucopyranose, GALACTOSYL TRANSFERASE LGTC, MANGANESE (II) ION, ...
Authors:Persson, K, Ly, H.D, Diekelmann, M, Wakarchuk, W.W, Withers, S.G, Strynadka, N.C.J.
Deposit date:2000-11-29
Release date:2001-02-14
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the retaining galactosyltransferase LgtC from Neisseria meningitidis in complex with donor and acceptor sugar analogs.
Nat.Struct.Biol., 8, 2001
1XDY
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Structural and Biochemical Identification of a Novel Bacterial Oxidoreductase, W-containing cofactor
Descriptor: Bacterial Sulfite Oxidase, PHOSPHONIC ACIDMONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,7,8A,9,10,10A-HEXAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL)ESTER, TUNGSTEN ION
Authors:Loschi, L, Brokx, S.J, Hills, T.L, Zhang, G, Bertero, M.G, Lovering, A.L, Weiner, J.H, Strynadka, N.C.
Deposit date:2004-09-08
Release date:2004-10-12
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and biochemical identification of a novel bacterial oxidoreductase.
J.Biol.Chem., 279, 2004
1XA7
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BU of 1xa7 by Molmil
Crystal structure of the benzylpenicillin-acylated BlaR1 sensor domain from Staphylococcus aureus
Descriptor: OPEN FORM - PENICILLIN G, Regulatory protein BlaR1
Authors:Wilke, M.S, Hills, T.L, Zhang, H.Z, Chambers, H.F, Strynadka, N.C.
Deposit date:2004-08-25
Release date:2004-09-21
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of the Apo and penicillin-acylated forms of the BlaR1 beta-lactam sensor of Staphylococcus aureus.
J.Biol.Chem., 279, 2004
1XDQ
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BU of 1xdq by Molmil
Structural and Biochemical Identification of a Novel Bacterial Oxidoreductase
Descriptor: Bacterial Sulfite Oxidase, MOLYBDENUM ATOM, OXYGEN ATOM, ...
Authors:Loschi, L, Brokx, S.J, Hills, T.L, Zhang, G, Bertero, M.G, Lovering, A.L, Weiner, J.H, Strynadka, N.C.
Deposit date:2004-09-07
Release date:2004-10-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural and biochemical identification of a novel bacterial oxidoreductase.
J.Biol.Chem., 279, 2004
1FOF
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BU of 1fof by Molmil
CRYSTAL STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-10
Descriptor: BETA LACTAMASE OXA-10, COBALT (II) ION, SULFATE ION
Authors:Paetzel, M, Danel, F, de Castro, L, Mosimann, S.C, Page, M.G.P, Strynadka, N.C.J.
Deposit date:2000-08-28
Release date:2000-10-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the class D beta-lactamase OXA-10.
Nat.Struct.Biol., 7, 2000
1XUU
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BU of 1xuu by Molmil
Crystal structure of sialic acid synthase (NeuB) in complex with Mn2+ and Malate from Neisseria meningitidis
Descriptor: D-MALATE, MANGANESE (II) ION, polysialic acid capsule biosynthesis protein SiaC
Authors:Gunawan, J, Simard, D, Gilbert, M, Lovering, A.L, Wakarchuk, W.W, Tanner, M.E, Strynadka, N.C.
Deposit date:2004-10-26
Release date:2004-11-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and mechanistic analysis of sialic acid synthase NeuB from Neisseria meningitidis in complex with Mn2+, phosphoenolpyruvate, and N-acetylmannosaminitol.
J.Biol.Chem., 280, 2005
3UJZ
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BU of 3ujz by Molmil
Crystal structure of enterohemorrhagic E. coli StcE
Descriptor: Metalloprotease stcE, ZINC ION
Authors:Yu, A.C.Y, Strynadka, N.C.J.
Deposit date:2011-11-08
Release date:2012-05-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Insight into the Bacterial Mucinase StcE Essential to Adhesion and Immune Evasion during Enterohemorrhagic E. coli Infection.
Structure, 20, 2012
1G68
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BU of 1g68 by Molmil
PSE-4 CARBENICILLINASE, WILD TYPE
Descriptor: BETA-LACTAMASE PSE-4, SULFATE ION
Authors:Lim, D, Sanschagrin, F, Passmore, L, De Castro, L, Levesque, R.C, Strynadka, N.C.J.
Deposit date:2000-11-03
Release date:2001-02-21
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Insights into the molecular basis for the carbenicillinase activity of PSE-4 beta-lactamase from crystallographic and kinetic studies.
Biochemistry, 40, 2001
1XSK
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BU of 1xsk by Molmil
Structure of a Family 31 alpha glycosidase glycosyl-enzyme intermediate
Descriptor: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, 5(R)-fluoro-beta-D-xylopyranose, Putative family 31 glucosidase yicI, ...
Authors:Lovering, A.L, Lee, S.S, Kim, Y.W, Withers, S.G, Strynadka, N.C.
Deposit date:2004-10-19
Release date:2004-11-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mechanistic and Structural Analysis of a Family 31 {alpha}-Glycosidase and Its Glycosyl-enzyme Intermediate
J.Biol.Chem., 280, 2005
1XUZ
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BU of 1xuz by Molmil
Crystal structure analysis of sialic acid synthase (NeuB)from Neisseria meningitidis, bound to Mn2+, Phosphoenolpyruvate, and N-acetyl mannosaminitol
Descriptor: 5-DEOXY-5-{[(1S)-1-HYDROXYETHYL]AMINO}-D-GLUCITOL, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, ...
Authors:Gunawan, J, Simard, D, Gilbert, M, Lovering, A.L, Wakarchuk, W.W, Tanner, M.E, Strynadka, N.C.
Deposit date:2004-10-26
Release date:2004-11-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and mechanistic analysis of sialic acid synthase NeuB from Neisseria meningitidis in complex with Mn2+, phosphoenolpyruvate, and N-acetylmannosaminitol.
J.Biol.Chem., 280, 2005
1G6A
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BU of 1g6a by Molmil
PSE-4 CARBENICILLINASE, R234K MUTANT
Descriptor: BETA-LACTAMASE PSE-4, SULFATE ION
Authors:Lim, D, Sanschagrin, F, Passmore, L, De Castro, L, Levesque, R.C, Strynadka, N.C.J.
Deposit date:2000-11-03
Release date:2001-02-21
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Insights into the molecular basis for the carbenicillinase activity of PSE-4 beta-lactamase from crystallographic and kinetic studies.
Biochemistry, 40, 2001
1XSI
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BU of 1xsi by Molmil
Structure of a Family 31 alpha glycosidase
Descriptor: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ACETIC ACID, Putative family 31 glucosidase yicI, ...
Authors:Lovering, A.L, Lee, S.S, Kim, Y.W, Withers, S.G, Strynadka, N.C.
Deposit date:2004-10-19
Release date:2004-10-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mechanistic and Structural Analysis of a Family 31 alpha-Glycosidase and Its Glycosyl-enzyme Intermediate
J.Biol.Chem., 280, 2005
1XSJ
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BU of 1xsj by Molmil
Structure of a Family 31 alpha glycosidase
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Putative family 31 glucosidase yicI
Authors:Lovering, A.L, Lee, S.S, Kim, Y.W, Withers, S.G, Strynadka, N.C.
Deposit date:2004-10-19
Release date:2004-10-26
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanistic and Structural Analysis of a Family 31 alpha-Glycosidase and Its Glycosyl-enzyme Intermediate
J.Biol.Chem., 280, 2005
1Y9L
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The X-ray structure of an secretion system protein
Descriptor: ACETATE ION, Lipoprotein mxiM, UNDECANE
Authors:Lario, P.I, Pfuetzer, R.A, Frey, E.A, Creagh, L, Haynes, C, Maurelli, A.T, Strynadka, N.C.
Deposit date:2004-12-15
Release date:2005-04-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure and biochemical analysis of a secretin pilot protein.
Embo J., 24, 2005

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