8Y1D
| 2up-TM conformation of HKU1-B S protein after incubation of the receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Xia, L.Y, Zhang, Y.Y, Zhou, Q. | Deposit date: | 2024-01-24 | Release date: | 2024-05-01 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2. Cell Res., 34, 2024
|
|
8Y1G
| The 1up conformation of the HKU1-B S protein in the apo state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Xia, L.Y, Zhang, Y.Y, Zhou, Q. | Deposit date: | 2024-01-24 | Release date: | 2024-05-01 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.99 Å) | Cite: | Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2. Cell Res., 34, 2024
|
|
8Y1A
| 1up-1 conformation of HKU1-B S protein after incubation of the receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Xia, L.Y, Zhang, Y.Y, Zhou, Q. | Deposit date: | 2024-01-24 | Release date: | 2024-05-01 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2. Cell Res., 34, 2024
|
|
8Y1H
| The 2up formation of the HKU1-B S protein in the apo state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Xia, L.Y, Zhang, Y.Y, Zhou, Q. | Deposit date: | 2024-01-24 | Release date: | 2024-05-01 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.16 Å) | Cite: | Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2. Cell Res., 34, 2024
|
|
8Y1B
| 1up-2 conformation of HKU1-B S protein after incubation of the receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Xia, L.Y, Zhang, Y.Y, Zhou, Q. | Deposit date: | 2024-01-24 | Release date: | 2024-05-01 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2. Cell Res., 34, 2024
|
|
8Y1C
| 2up-1 conformation of HKU1-B S protein after incubation of the receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Xia, L.Y, Zhang, Y.Y, Zhou, Q. | Deposit date: | 2024-01-24 | Release date: | 2024-05-01 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2. Cell Res., 34, 2024
|
|
8Y1F
| The closed conformation of the HKU1-B S protein in the apo state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Xia, L.Y, Zhang, Y.Y, Zhou, Q. | Deposit date: | 2024-01-24 | Release date: | 2024-05-01 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2. Cell Res., 34, 2024
|
|
8Y19
| Closed conformation of HKU1-B S protein after incubation of the receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Xia, L.Y, Zhang, Y.Y, Zhou, Q. | Deposit date: | 2024-01-24 | Release date: | 2024-05-01 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2. Cell Res., 34, 2024
|
|
8Y1E
| 3up-TM conformation of HKU1-B S protein after incubation of the receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Xia, L.Y, Zhang, Y.Y, Zhou, Q. | Deposit date: | 2024-01-24 | Release date: | 2024-05-01 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural basis for the recognition of HCoV-HKU1 by human TMPRSS2. Cell Res., 34, 2024
|
|
1I8L
| HUMAN B7-1/CTLA-4 CO-STIMULATORY COMPLEX | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CYTOTOXIC T-LYMPHOCYTE PROTEIN 4, T LYMPHOCYTE ACTIVATION ANTIGEN CD80, ... | Authors: | Stamper, C.C, Somers, W.S, Mosyak, L. | Deposit date: | 2001-03-14 | Release date: | 2001-04-04 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses. Nature, 410, 2001
|
|
7YG6
| Cryo-EM structure of the EfPiwi(N959K) in complex with piRNA | Descriptor: | MAGNESIUM ION, Piwi, piRNA | Authors: | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | Deposit date: | 2022-07-11 | Release date: | 2024-01-24 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing. Nat.Struct.Mol.Biol., 2024
|
|
7YGN
| Cryo-EM structure of the Mili in complex with piRNA | Descriptor: | MAGNESIUM ION, Piwi-like protein 2, piRNA | Authors: | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | Deposit date: | 2022-07-11 | Release date: | 2024-01-24 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing. Nat.Struct.Mol.Biol., 2024
|
|
7YFX
| Cryo-EM structure of Hili in complex with piRNA | Descriptor: | MAGNESIUM ION, Piwi-like protein 2, piRNA | Authors: | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | Deposit date: | 2022-07-09 | Release date: | 2024-01-24 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing. Nat.Struct.Mol.Biol., 2024
|
|
7YFQ
| Cryo-EM structure of the EfPiwi (N959K)-piRNA-target ternary complex | Descriptor: | MAGNESIUM ION, Piwi, RNA (5'-R(*UP*CP*CP*AP*UP*GP*UP*UP*GP*AP*UP*GP*GP*UP*AP*A)-3'), ... | Authors: | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | Deposit date: | 2022-07-08 | Release date: | 2024-02-14 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing. Nat.Struct.Mol.Biol., 2024
|
|
7CGN
| The overall structure of the MlaFEDB complex in ATP-bound EQtall conformation (Mutation of E170Q on MlaF) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Lipid asymmetry maintenance ABC transporter permease subunit MlaE, Lipid asymmetry maintenance protein MlaB, ... | Authors: | Chi, X.M, Fan, Q.X, Zhang, Y.Y, Liang, K, Zhou, Q, Li, Y.Y. | Deposit date: | 2020-07-01 | Release date: | 2020-09-09 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural mechanism of phospholipids translocation by MlaFEDB complex. Cell Res., 30, 2020
|
|
7CGE
| The overall structure of nucleotide free MlaFEDB complex | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, Lipid asymmetry maintenance ABC transporter permease subunit MlaE, Lipid asymmetry maintenance protein MlaB, ... | Authors: | Chi, X.M, Fan, Q.X, Zhang, Y.Y, Liang, K, Zhou, Q, Li, Y.Y. | Deposit date: | 2020-07-01 | Release date: | 2020-09-09 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural mechanism of phospholipids translocation by MlaFEDB complex. Cell Res., 30, 2020
|
|
7C8D
| Cryo-EM structure of cat ACE2 and SARS-CoV-2 RBD | Descriptor: | Angiotensin-converting enzyme 2, Spike protein S1, ZINC ION | Authors: | Gao, G.F, Wang, Q.H, Wu, L.l. | Deposit date: | 2020-05-29 | Release date: | 2020-09-02 | Last modified: | 2020-12-02 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Broad host range of SARS-CoV-2 and the molecular basis for SARS-CoV-2 binding to cat ACE2. Cell Discov, 6, 2020
|
|
7CH0
| The overall structure of the MlaFEDB complex in ATP-bound EQclose conformation (Mutation of E170Q on MlaF) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Lipid asymmetry maintenance ABC transporter permease subunit MlaE, Lipid asymmetry maintenance protein MlaB, ... | Authors: | Chi, X.M, Fan, Q.X, Zhang, Y.Y, Liang, K, Zhou, Q, Li, Y.Y. | Deposit date: | 2020-07-03 | Release date: | 2020-09-09 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural mechanism of phospholipids translocation by MlaFEDB complex. Cell Res., 30, 2020
|
|
7CF9
| Structure of RyR1 (Ca2+/CHL) | Descriptor: | 5-bromanyl-N-[4-chloranyl-2-methyl-6-(methylcarbamoyl)phenyl]-2-(3-chloranylpyridin-2-yl)pyrazole-3-carboxamide, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... | Authors: | Ma, R, Haji-Ghassemi, O, Ma, D, Lin, L, Samurkas, A, Van Petegem, F, Yuchi, Z. | Deposit date: | 2020-06-24 | Release date: | 2020-09-02 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Structural basis for diamide modulation of ryanodine receptor. Nat.Chem.Biol., 16, 2020
|
|
1FPI
| FRUCTOSE-1,6-BISPHOSPHATASE (D-FRUCTOSE-1,6-BISPHOSPHATE 1-PHOSPHOHYDROLASE) COMPLEXED WITH AMP, 2,5-ANHYDRO-D-GLUCITOL-1,6-BISPHOSPHATE AND POTASSIUM IONS (100 MM) | Descriptor: | 2,5-anhydro-1,6-di-O-phosphono-D-glucitol, ADENOSINE MONOPHOSPHATE, FRUCTOSE-1,6-BISPHOSPHATASE, ... | Authors: | Villeret, V, Lipscomb, W.N. | Deposit date: | 1995-06-02 | Release date: | 1996-06-20 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystallographic evidence for the action of potassium, thallium, and lithium ions on fructose-1,6-bisphosphatase. Proc.Natl.Acad.Sci.USA, 92, 1995
|
|
7YPE
| |
7YPF
| |
1FPJ
| FRUCTOSE-1,6-BISPHOSPHATASE (D-FRUCTOSE-1,6-BISPHOSPHATE 1-PHOSPHOHYDROLASE) COMPLEXED WITH AMP, 2,5-ANHYDRO-D-GLUCITOL-1,6-BISPHOSPHATE, THALLIUM (10 MM) AND LITHIUM IONS (10 MM) | Descriptor: | 2,5-anhydro-1,6-di-O-phosphono-D-glucitol, ADENOSINE MONOPHOSPHATE, FRUCTOSE-1,6-BISPHOSPHATASE, ... | Authors: | Villeret, V, Lipscomb, W.N. | Deposit date: | 1995-06-02 | Release date: | 1996-06-20 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystallographic evidence for the action of potassium, thallium, and lithium ions on fructose-1,6-bisphosphatase. Proc.Natl.Acad.Sci.USA, 92, 1995
|
|
5C9C
| CRYSTAL STRUCTURE OF BRAF(V600E) IN COMPLEX WITH LY3009120 COMPND | Descriptor: | 1-(3,3-dimethylbutyl)-3-{2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl}urea, CHLORIDE ION, Serine/threonine-protein kinase B-raf | Authors: | Edwards, T, Abendroth, J, Chun, L. | Deposit date: | 2015-06-26 | Release date: | 2015-07-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Inhibition of RAF Isoforms and Active Dimers by LY3009120 Leads to Anti-tumor Activities in RAS or BRAF Mutant Cancers. Cancer Cell, 28, 2015
|
|
7CV9
| RNA methyltransferase METTL4 | Descriptor: | GLYCEROL, Methyltransferase-like protein 2, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Luo, Q, Ma, J. | Deposit date: | 2020-08-25 | Release date: | 2021-09-01 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.455 Å) | Cite: | Structural insights into molecular mechanism for N6-adenosine methylation by MT-A70 family methyltransferase METTL4 Nat Commun, 13, 2022
|
|