3GIT
 
 | | Crystal structure of a truncated acetyl-CoA synthase | | Descriptor: | Carbon monoxide dehydrogenase/acetyl-CoA synthase subunit alpha, GLYCEROL, HYDROSULFURIC ACID, ... | | Authors: | Volbeda, A, Darnault, C, Fontecilla-Camps, J.C. | | Deposit date: | 2009-03-06 | | Release date: | 2009-10-06 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Novel domain arrangement in the crystal structure of a truncated acetyl-CoA synthase from Moorella thermoacetica
Biochemistry, 48, 2009
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6WUT
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6WUJ
 | | Mitochondrial SAM complex - monomer in detergent | | Descriptor: | Bac_surface_Ag domain-containing protein, Sam35, Tom37 domain-containing protein | | Authors: | Ni, X, Botos, I, Diederichs, K. | | Deposit date: | 2020-05-04 | | Release date: | 2020-08-12 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural insight into mitochondrial beta-barrel outer membrane protein biogenesis.
Nat Commun, 11, 2020
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6WUM
 | | Mitochondrial SAM complex - dimer 2 in detergent | | Descriptor: | Bac_surface_Ag domain-containing protein, Sam35, Tom37 domain-containing protein | | Authors: | Ni, X, Botos, I, Diederichs, K. | | Deposit date: | 2020-05-04 | | Release date: | 2020-08-12 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural insight into mitochondrial beta-barrel outer membrane protein biogenesis.
Nat Commun, 11, 2020
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6WUH
 | | Mitochondrial SAM complex in lipid nanodiscs | | Descriptor: | Bac_surface_Ag domain-containing protein, Sam35, Tom37 domain-containing protein | | Authors: | Ni, X, Botos, I, Diederichs, K. | | Deposit date: | 2020-05-04 | | Release date: | 2020-08-12 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural insight into mitochondrial beta-barrel outer membrane protein biogenesis.
Nat Commun, 11, 2020
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6WQZ
 | | Structure of human ATG9A, the only transmembrane protein of the core autophagy machinery | | Descriptor: | Autophagy-related protein 9A, Lauryl Maltose Neopentyl Glycol | | Authors: | Guardia, C.M, Tan, X, Lian, T, Rana, M.S, Zhou, W, Christenson, E.T, Lowry, A.J, Faraldo-Gomez, J.D, Bonifacino, J.S, Jiang, J, Banerjee, A. | | Deposit date: | 2020-04-29 | | Release date: | 2020-07-08 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structure of Human ATG9A, the Only Transmembrane Protein of the Core Autophagy Machinery.
Cell Rep, 31, 2020
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6WUN
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6WUL
 | | Mitochondrial SAM complex - dimer 1 in detergent | | Descriptor: | Bac_surface_Ag domain-containing protein, Sam35, Tom37 domain-containing protein | | Authors: | Ni, X, Botos, I, Diederichs, K. | | Deposit date: | 2020-05-04 | | Release date: | 2020-08-12 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural insight into mitochondrial beta-barrel outer membrane protein biogenesis.
Nat Commun, 11, 2020
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6WR4
 | | Structure of human ATG9A, the only transmembrane protein of the core autophagy machinery | | Descriptor: | Autophagy-related protein 9A, Lauryl Maltose Neopentyl Glycol | | Authors: | Guardia, C.M, Tan, X, Lian, T, Rana, M.S, Zhou, W, Christenson, E.T, Lowry, A.J, Faraldo-Gomez, J.D, Bonifacino, J.S, Jiang, J, Banerjee, A. | | Deposit date: | 2020-04-29 | | Release date: | 2020-07-08 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structure of Human ATG9A, the Only Transmembrane Protein of the Core Autophagy Machinery.
Cell Rep, 31, 2020
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5TMH
 | | Structure of Zika virus NS5 | | Descriptor: | GLYCEROL, Polyprotein, S-ADENOSYL-L-HOMOCYSTEINE, ... | | Authors: | Wang, B, Tan, X, Song, J. | | Deposit date: | 2016-10-12 | | Release date: | 2017-02-08 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (3.278 Å) | | Cite: | The structure of Zika virus NS5 reveals a conserved domain conformation.
Nat Commun, 8, 2017
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5GTX
 | | Crystal structure of mutated buckwheat glutaredoxin | | Descriptor: | buckwheat glutaredoxin | | Authors: | Zhang, X, Wang, W, Zhao, Y, Wang, Z, Wang, H. | | Deposit date: | 2016-08-23 | | Release date: | 2017-07-05 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Structural insights into the binding of buckwheat glutaredoxin with GSH and regulation of its catalytic activity
J. Inorg. Biochem., 173, 2017
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5BWA
 | | Crystal structure of ODC-PLP-AZ1 ternary complex | | Descriptor: | Ornithine decarboxylase, Ornithine decarboxylase antizyme 1, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Wu, D.H. | | Deposit date: | 2015-06-07 | | Release date: | 2015-12-09 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural basis of Ornithine Decarboxylase inactivation and accelerated degradation by polyamine sensor Antizyme1
Sci Rep, 5, 2015
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2EVQ
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7DGD
 | | apo state of class C GPCR | | Descriptor: | Metabotropic glutamate receptor 1 | | Authors: | Zhang, J.Y, Wu, L.J, Luo, F, Hua, T, Liu, Z.J. | | Deposit date: | 2020-11-11 | | Release date: | 2021-09-22 | | Method: | ELECTRON MICROSCOPY (3.96 Å) | | Cite: | Structural insights into the activation initiation of full-length mGlu1.
Protein Cell, 12, 2021
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7DGE
 | | intermediate state of class C GPCR | | Descriptor: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Metabotropic glutamate receptor 1, nanobody | | Authors: | Zhang, J.Y, Wu, L.J, Luo, F, Hua, T, Liu, Z.J. | | Deposit date: | 2020-11-11 | | Release date: | 2021-09-22 | | Method: | ELECTRON MICROSCOPY (3.65 Å) | | Cite: | Structural insights into the activation initiation of full-length mGlu1.
Protein Cell, 12, 2021
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5D9Y
 | | Crystal structure of TET2-5fC complex | | Descriptor: | DNA (5'-D(*AP*CP*TP*GP*TP*(5FC)P*GP*AP*AP*GP*CP*T)-3'), DNA (5'-D(*AP*GP*CP*TP*TP*CP*GP*AP*CP*AP*GP*T)-3'), FE (III) ION, ... | | Authors: | Hu, L, Cheng, J, Rao, Q, Li, Z, Li, J, Xu, Y. | | Deposit date: | 2015-08-19 | | Release date: | 2015-11-04 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.971 Å) | | Cite: | Structural insight into substrate preference for TET-mediated oxidation.
Nature, 527, 2015
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5DEU
 | | Crystal structure of TET2-5hmC complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, DNA (5'-D(*AP*CP*CP*AP*CP*(5HC)P*GP*GP*TP*GP*GP*T)-3'), ... | | Authors: | Hu, L, Cheng, J, Rao, Q, Li, Z, Li, J, Xu, Y. | | Deposit date: | 2015-08-26 | | Release date: | 2015-11-04 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.801 Å) | | Cite: | Structural insight into substrate preference for TET-mediated oxidation.
Nature, 527, 2015
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5HLU
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7F4W
 | | Complex structure of HLA2402 with recognizing SARS-CoV-2 epitope pep4 | | Descriptor: | Beta-2-microglobulin, MHC class I antigen, SARS-CoV-2 T-cell Epitope pep4 | | Authors: | Deng, S, Jin, T. | | Deposit date: | 2021-06-21 | | Release date: | 2021-08-25 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Profiling CD8 + T cell epitopes of COVID-19 convalescents reveals reduced cellular immune responses to SARS-CoV-2 variants.
Cell Rep, 36, 2021
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7EU2
 | | Complex structure of HLA0201 with recognizing SARS-CoV-2 epitope S1 | | Descriptor: | Beta-2-microglobulin, MHC class I antigen, SARS-CoV-2 T-cell Epitope S1 | | Authors: | Deng, S, Jin, T. | | Deposit date: | 2021-05-15 | | Release date: | 2021-08-25 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Profiling CD8 + T cell epitopes of COVID-19 convalescents reveals reduced cellular immune responses to SARS-CoV-2 variants.
Cell Rep, 36, 2021
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4R9I
 | | Crystal structure of cysteine proteinase inhibitor Serpin18 from Bombyx mori | | Descriptor: | BETA-MERCAPTOETHANOL, CITRATE ANION, SODIUM ION, ... | | Authors: | Guo, P.C, He, H.W, Zhao, P, Xia, Q.Y. | | Deposit date: | 2014-09-05 | | Release date: | 2015-09-09 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structural insights into the unique inhibitory mechanism of the silkworm protease inhibitor serpin18
Sci Rep, 5, 2015
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6AX6
 | | The crystal structure of a lysyl hydroxylase from Acanthamoeba polyphaga mimivirus | | Descriptor: | FE (II) ION, IODIDE ION, Procollagen lysyl hydroxylase and glycosyltransferase | | Authors: | Guo, H, Tsai, C, Miller, M.D, Alvarado, S, Tainer, J.A, Phillips Jr, G.N, Kurie, J.M. | | Deposit date: | 2017-09-06 | | Release date: | 2018-02-21 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.241 Å) | | Cite: | Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding.
Nat Commun, 9, 2018
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6B9L
 | | Crystal structure of EphA2 with peptide 135E2 | | Descriptor: | Ephrin type-A receptor 2, HIS TAG CLEAVED OFF, peptide 135E2, ... | | Authors: | Song, J, Tan, X. | | Deposit date: | 2017-10-10 | | Release date: | 2018-10-17 | | Last modified: | 2024-07-10 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structure-Based Design of Novel EphA2 Agonistic Agents with Nanomolar Affinity in Vitro and in Cell.
ACS Chem. Biol., 13, 2018
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3S2X
 | | Structure of acetyl-Coenzyme A synthase Alpha subunit C-terminal domain | | Descriptor: | NICKEL (II) ION, acetyl-CoA synthase subunit alpha | | Authors: | Li, P. | | Deposit date: | 2011-05-17 | | Release date: | 2011-07-27 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Insights into the Mechanistic Role of the [Fe(4) S(4) ] Cubane in the A-Cluster {[Fe(4) S(4) ]-(SR)-[Ni(p) Ni(d) ]} of Acetyl-Coenzyme A Synthase.
Chembiochem, 12, 2011
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6AX7
 | | The crystal structure of a lysyl hydroxylase from Acanthamoeba polyphaga mimivirus | | Descriptor: | FE (II) ION, Procollagen lysyl hydroxylase and glycosyltransferase | | Authors: | Guo, H, Tsai, C, Miller, M.D, Alvarado, S, Tainer, J.A, Phillips Jr, G.N, Kurie, J.M. | | Deposit date: | 2017-09-06 | | Release date: | 2018-02-21 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.002 Å) | | Cite: | Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding.
Nat Commun, 9, 2018
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