5N4V
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![BU of 5n4v by Molmil](/molmil-images/mine/5n4v) | Crystal structure of human Pim-1 kinase in complex with a consensuspeptide and fragment like molekule 2-cyclopropyl-4,5-dimethylthieno[5,4-d]pyrimidine-6-carboxylic acid | Descriptor: | 2-cyclopropyl-4,5-dimethyl-thieno[2,3-d]pyrimidine-6-carboxylic acid, GLYCEROL, Pimtide, ... | Authors: | Siefker, C, Heine, A, Klebe, G. | Deposit date: | 2017-02-11 | Release date: | 2018-02-28 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | A crystallographic fragment study with human Pim-1 kinase to be published
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1N4H
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![BU of 1n4h by Molmil](/molmil-images/mine/1n4h) | Characterization of ligands for the orphan nuclear receptor RORbeta | Descriptor: | Nuclear Receptor ROR-beta, RETINOIC ACID, Steroid Receptor Coactivator-1 | Authors: | Stehlin-Gaon, C, Willmann, D, Sanglier, S, Van Dorsselaer, A, Renaud, J.-P, Moras, D, Schuele, R. | Deposit date: | 2002-10-31 | Release date: | 2003-09-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | All-trans retinoic acid is a ligand for the orphan nuclear receptor RORbeta Nat.Struct.Biol., 10, 2003
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8BEO
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![BU of 8beo by Molmil](/molmil-images/mine/8beo) | Crystal structure of E. coli glyoxylate carboligase mutant I393A with MAP | Descriptor: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2,3-DIMETHOXY-5-METHYL-1,4-BENZOQUINONE, ... | Authors: | Shaanan, B, Binshtein, E. | Deposit date: | 2022-10-21 | Release date: | 2023-11-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Crystal structure of E. coli glyoxylate carboligase mutant I393A with MAP To Be Published
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4G55
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![BU of 4g55 by Molmil](/molmil-images/mine/4g55) | Clathrin terminal domain complexed with pitstop 2 | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Clathrin heavy chain 1, ... | Authors: | Bulut, H, Von Kleist, L, Saenger, W, Haucke, V. | Deposit date: | 2012-07-17 | Release date: | 2012-08-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition. Cell(Cambridge,Mass.), 146, 2011
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6NMJ
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![BU of 6nmj by Molmil](/molmil-images/mine/6nmj) | Crystal Structure of Rat Ric-8A G alpha binding domain, "Paratone-N Immersed" | Descriptor: | Resistance to inhibitors of cholinesterase 8 homolog A (C. elegans) | Authors: | Zeng, B, Mou, T.C, Sprang, S.R. | Deposit date: | 2019-01-11 | Release date: | 2019-06-26 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure, Function, and Dynamics of the G alpha Binding Domain of Ric-8A. Structure, 27, 2019
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6NMG
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![BU of 6nmg by Molmil](/molmil-images/mine/6nmg) | Crystal Structure of Rat Ric-8A G alpha binding domain | Descriptor: | Resistance to inhibitors of cholinesterase 8 homolog A (C. elegans), SULFATE ION | Authors: | Zeng, B, Mou, T.C, Sprang, S.R. | Deposit date: | 2019-01-10 | Release date: | 2019-06-26 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure, Function, and Dynamics of the G alpha Binding Domain of Ric-8A. Structure, 27, 2019
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6R4V
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![BU of 6r4v by Molmil](/molmil-images/mine/6r4v) | Crystal structure of human geranylgeranyl diphosphate synthase bound to ibandronate | Descriptor: | GLYCEROL, Geranylgeranyl pyrophosphate synthase, IBANDRONATE, ... | Authors: | Lisnyansky, M, Giladi, M, Haitin, Y. | Deposit date: | 2019-03-24 | Release date: | 2019-09-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.202 Å) | Cite: | Metal Coordination Is Crucial for Geranylgeranyl Diphosphate Synthase-Bisphosphonate Interactions: A Crystallographic and Computational Analysis. Mol.Pharmacol., 96, 2019
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1KV6
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![BU of 1kv6 by Molmil](/molmil-images/mine/1kv6) | X-ray structure of the orphan nuclear receptor ERR3 ligand-binding domain in the constitutively active conformation | Descriptor: | ESTROGEN-RELATED RECEPTOR GAMMA, steroid receptor coactivator 1 | Authors: | Greschik, H, Wurtz, J.-M, Sanglier, S, Bourguet, W, van Dorsselaer, A, Moras, D, Renaud, J.-P, Structural Proteomics in Europe (SPINE) | Deposit date: | 2002-01-25 | Release date: | 2003-01-25 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and Functional Evidence for Ligand-Independent Transcriptional Activation by the Estrogen-Related Receptor 3 Mol.Cell, 9, 2002
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6UR5
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![BU of 6ur5 by Molmil](/molmil-images/mine/6ur5) | |
5MJ1
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![BU of 5mj1 by Molmil](/molmil-images/mine/5mj1) | Extracellular domain of human CD83 - rhombohedral crystal form | Descriptor: | CD83 antigen, DI(HYDROXYETHYL)ETHER | Authors: | Klingl, S, Egerer-Sieber, C, Schmid, B, Weiler, S, Muller, Y.A. | Deposit date: | 2016-11-29 | Release date: | 2017-03-29 | Last modified: | 2018-03-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of the Extracellular Domain of the Human Dendritic Cell Surface Marker CD83. J. Mol. Biol., 429, 2017
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5MJ2
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![BU of 5mj2 by Molmil](/molmil-images/mine/5mj2) | Extracellular domain of human CD83 - rhombohedral crystal form after UV-RIP (S-SAD data) | Descriptor: | CD83 antigen, DI(HYDROXYETHYL)ETHER | Authors: | Klingl, S, Egerer-Sieber, C, Schmid, B, Weiler, S, Muller, Y.A. | Deposit date: | 2016-11-29 | Release date: | 2017-03-29 | Last modified: | 2018-03-07 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Crystal Structure of the Extracellular Domain of the Human Dendritic Cell Surface Marker CD83. J. Mol. Biol., 429, 2017
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5MIX
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![BU of 5mix by Molmil](/molmil-images/mine/5mix) | |
5MJ0
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![BU of 5mj0 by Molmil](/molmil-images/mine/5mj0) | |
3RMR
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![BU of 3rmr by Molmil](/molmil-images/mine/3rmr) | |
2FDD
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![BU of 2fdd by Molmil](/molmil-images/mine/2fdd) | Crystal structure of HIV protease D545701 bound with GW0385 | Descriptor: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL [(1S,2R)-3-[(1,3-BENZODIOXOL-5-YLSULFONYL)(ISOBUTYL)AMINO]-2-HYDROXY-1-{4-[(2-METHYL-1,3-THIAZOL-4-YL)METHOXY]BENZYL}PROPYL]CARBAMATE, Gag-Pol polyprotein | Authors: | Xu, R.X. | Deposit date: | 2005-12-13 | Release date: | 2006-02-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Ultra-potent P1 modified arylsulfonamide HIV protease inhibitors: The discovery of GW0385. Bioorg.Med.Chem.Lett., 16, 2006
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2FDE
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![BU of 2fde by Molmil](/molmil-images/mine/2fde) | Wild type HIV protease bound with GW0385 | Descriptor: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL [(1S,2R)-3-[(1,3-BENZODIOXOL-5-YLSULFONYL)(ISOBUTYL)AMINO]-2-HYDROXY-1-{4-[(2-METHYL-1,3-THIAZOL-4-YL)METHOXY]BENZYL}PROPYL]CARBAMATE, Gag-Pol polyprotein, POTASSIUM ION | Authors: | Xu, R.X. | Deposit date: | 2005-12-13 | Release date: | 2006-02-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Ultra-potent P1 modified arylsulfonamide HIV protease inhibitors: The discovery of GW0385. Bioorg.Med.Chem.Lett., 16, 2006
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2NRF
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![BU of 2nrf by Molmil](/molmil-images/mine/2nrf) | Crystal Structure of GlpG, a Rhomboid family intramembrane protease | Descriptor: | Protein GlpG | Authors: | Wu, Z, Yan, N, Feng, L, Yan, H, Gu, L, Shi, Y. | Deposit date: | 2006-11-02 | Release date: | 2006-11-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural analysis of a rhomboid family intramembrane protease reveals a gating mechanism for substrate entry. Nat.Struct.Mol.Biol., 13, 2006
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1DBA
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![BU of 1dba by Molmil](/molmil-images/mine/1dba) | |
1DBB
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![BU of 1dbb by Molmil](/molmil-images/mine/1dbb) | |
1DBM
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![BU of 1dbm by Molmil](/molmil-images/mine/1dbm) | |
1DBJ
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![BU of 1dbj by Molmil](/molmil-images/mine/1dbj) | |
1DBK
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![BU of 1dbk by Molmil](/molmil-images/mine/1dbk) | |
3OMZ
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![BU of 3omz by Molmil](/molmil-images/mine/3omz) | |
4E1T
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![BU of 4e1t by Molmil](/molmil-images/mine/4e1t) | X-ray crystal structure of the transmembrane beta-domain from invasin from Yersinia pseudotuberculosis | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Invasin | Authors: | Fairman, J.W, Dautin, N, Wojtowicz, D, Wei, L, Noinaj, N, Barnard, T.J, Udho, E, Finkelstein, A, Przytycka, T.M, Cherezov, V, Buchanan, S.K. | Deposit date: | 2012-03-07 | Release date: | 2012-06-13 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.263 Å) | Cite: | Crystal Structures of the Outer Membrane Domain of Intimin and Invasin from Enterohemorrhagic E. coli and Enteropathogenic Y. pseudotuberculosis. Structure, 20, 2012
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4E1S
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![BU of 4e1s by Molmil](/molmil-images/mine/4e1s) | X-ray crystal structure of the transmembrane beta-domain from intimin from EHEC strain O157:H7 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, ... | Authors: | Fairman, J.W, Dautin, N, Wojtowicz, D, Wei, L, Noinaj, N, Barnard, T.J, Udho, E, Finkelstein, A, Przytycka, T.M, Cherezov, V, Buchanan, S.K. | Deposit date: | 2012-03-07 | Release date: | 2012-06-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.855 Å) | Cite: | Crystal Structures of the Outer Membrane Domain of Intimin and Invasin from Enterohemorrhagic E. coli and Enteropathogenic Y. pseudotuberculosis. Structure, 20, 2012
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