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8EP9
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BU of 8ep9 by Molmil
The capsid structure of Human Parvovirus 4
Descriptor: Human Parvovirus 4
Authors:Mietzsch, M, McKenna, R.
Deposit date:2022-10-05
Release date:2022-11-09
Last modified:2025-05-28
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Capsid Structure of Aleutian Mink Disease Virus and Human Parvovirus 4: New Faces in the Parvovirus Family Portrait.
Viruses, 14, 2022
3RAA
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BU of 3raa by Molmil
Structural studies of AAV8 capsid transitions associated with endosomal trafficking
Descriptor: ADENOSINE MONOPHOSPHATE, Capsid protein
Authors:Nam, H.-J, Gurda, B, McKenna, R, Porter, M, Byrne, B, Salganik, M, Muzyczka, N, Agbandje-McKenna, M.
Deposit date:2011-03-27
Release date:2011-09-21
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural studies of adeno-associated virus serotype 8 capsid transitions associated with endosomal trafficking.
J.Virol., 85, 2011
3RA4
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BU of 3ra4 by Molmil
Structural studies of AAV8 capsid transitions associated with endosomal trafficking
Descriptor: Capsid protein, DNA (5'-D(*CP*A)-3')
Authors:Nam, H.-J, Gurda, B, McKenna, R, Porter, M, Byrne, B, Salganik, M, Muzyczka, N, Agbandje-McKenna, M.
Deposit date:2011-03-27
Release date:2011-09-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural studies of adeno-associated virus serotype 8 capsid transitions associated with endosomal trafficking.
J.Virol., 85, 2011
3RA2
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BU of 3ra2 by Molmil
Structural studies of AAV8 capsid transitions associated with endosomal trafficking
Descriptor: Capsid protein
Authors:Nam, H.-J, Gurda, B, McKenna, R, Porter, M, Byrne, B, Salganik, M, Muzyczka, N, Agbandje-McKenna, M.
Deposit date:2011-03-26
Release date:2011-09-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural studies of adeno-associated virus serotype 8 capsid transitions associated with endosomal trafficking.
J.Virol., 85, 2011
3RA9
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BU of 3ra9 by Molmil
Structural studies of AAV8 capsid transitions associated with endosomal trafficking
Descriptor: Capsid protein, DNA (5'-D(P*CP*A)-3')
Authors:Nam, H.-J, Gurda, B, McKenna, R, Porter, M, Byrne, B, Salganik, M, Muzyczka, N, Agbandje-McKenna, M.
Deposit date:2011-03-27
Release date:2011-09-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural studies of adeno-associated virus serotype 8 capsid transitions associated with endosomal trafficking.
J.Virol., 85, 2011
3RA8
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BU of 3ra8 by Molmil
Structural studies of AAV8 capsid transitions associated with endosomal trafficking
Descriptor: ADENOSINE MONOPHOSPHATE, Capsid protein
Authors:Nam, H.-J, Gurda, B, McKenna, R, Porter, M, Byrne, B, Salganik, M, Muzyczka, N, Agbandje-McKenna, M.
Deposit date:2011-03-27
Release date:2011-09-21
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural studies of adeno-associated virus serotype 8 capsid transitions associated with endosomal trafficking.
J.Virol., 85, 2011
5WLU
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BU of 5wlu by Molmil
Carbonic Anhydrase IX-mimic in complex with aryloxy-2-hydroxypropylammine sulfonamide
Descriptor: 4-{(2R)-2-hydroxy-3-[(propan-2-yl)amino]propoxy}-N-[2-(4-sulfamoylphenyl)ethyl]benzamide, Carbonic Anhydrase IX-mimic, ZINC ION
Authors:Lomelino, C.L, Andring, J.T, McKenna, R.
Deposit date:2017-07-27
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Hybrids for multitargeted therapy Beta Adrenergic Receptor modulators CAIs
To Be Published
5WLR
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BU of 5wlr by Molmil
Carbonic Anhydrase IX-mimic in complex with aryloxy-2-hydroxypropylammine sulfonamide
Descriptor: 4-{(2S)-2-hydroxy-3-[(propan-2-yl)amino]propoxy}benzene-1-sulfonamide, Carbonic Anhydrase IX-mimic, GLYCEROL, ...
Authors:Lomelino, C.L, Andring, J.T, McKenna, R.
Deposit date:2017-07-27
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Hybrids for multitargeted therapy Beta Adrenergic Receptor modulators CAIs
To Be Published
5WLT
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BU of 5wlt by Molmil
Carbonic Anhydrase IX-mimic in complex with aryloxy-2-hydroxypropylammine sulfonamide
Descriptor: 4-{(2S)-2-hydroxy-3-[(propan-2-yl)amino]propoxy}benzene-1-sulfonamide, Carbonic anhydrase 2, GLYCEROL, ...
Authors:Lomelino, C.L, Andring, J.T, McKenna, R.
Deposit date:2017-07-27
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Discovery of beta-Adrenergic Receptors Blocker-Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy.
J. Med. Chem., 61, 2018
5WLV
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BU of 5wlv by Molmil
Carbonic Anhydrase II in complex with aryloxy-2-hydroxypropylammine sulfonamide
Descriptor: 4-{(2R)-2-hydroxy-3-[(propan-2-yl)amino]propoxy}-N-[2-(4-sulfamoylphenyl)ethyl]benzamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ...
Authors:Lomelino, C.L, Andring, J.T, McKenna, R.
Deposit date:2017-07-27
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Discovery of beta-Adrenergic Receptors Blocker-Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy.
J. Med. Chem., 61, 2018
8FZ0
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BU of 8fz0 by Molmil
Cryo-EM Structure of empty AAV2 capsid
Descriptor: Capsid protein VP1
Authors:Bennett, A.D, McKenna, R.
Deposit date:2023-01-27
Release date:2023-05-31
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Cryo-EM Structure of genome containing AAV2
to be published
8FYW
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BU of 8fyw by Molmil
Cryo-EM Structure of genome containing AAV2
Descriptor: 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, Capsid protein VP1
Authors:Bennett, A.D, Mckenna, R.
Deposit date:2023-01-26
Release date:2023-06-07
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Cryo-EM Structure of genome containing AAV2
To Be Published
8FZN
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BU of 8fzn by Molmil
Cryo-EM Structure of AAV2-R404A Variant
Descriptor: Capsid protein VP1
Authors:Bennett, A.D, McKenna, R.
Deposit date:2023-01-29
Release date:2023-06-07
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Cryo-EM Structure of genome containing AAV2
to be published
1LZV
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BU of 1lzv by Molmil
Site-Specific Mutant (Tyr7 replaced with His) of Human Carbonic Anhydrase II
Descriptor: Carbonic Anhydrase II, ZINC ION
Authors:Tu, C.K, Qian, M, An, H, Wadhwa, N.R, Duda, D.M, Yoshioka, C, Pathak, Y, McKenna, R, Laipis, P.J, Silverman, D.N.
Deposit date:2002-06-11
Release date:2002-10-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Kinetic analysis of multiple proton shuttles in the active site of human carbonic anhydrase.
J.Biol.Chem., 277, 2002
8TEX
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BU of 8tex by Molmil
Avian Adeno-associated virus - empty capsid
Descriptor: Capsid protein
Authors:Hsi, J, Mietzsch, M, Chipman, P, Afione, S, Zeher, A, Huang, R, Chiorini, J, McKenna, R.
Deposit date:2023-07-07
Release date:2023-08-30
Last modified:2025-05-28
Method:ELECTRON MICROSCOPY (2.54 Å)
Cite:Structural and antigenic characterization of the avian adeno-associated virus capsid.
J.Virol., 97, 2023
8TEY
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BU of 8tey by Molmil
Avian Adeno-associated virus - empty capsid
Descriptor: 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, Capsid protein
Authors:Hsi, J, Mietzsch, M, Chipman, P, Afione, S, Zeher, A, Huang, R, Chiorini, J, McKenna, R.
Deposit date:2023-07-07
Release date:2023-08-30
Last modified:2025-05-28
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Structural and antigenic characterization of the avian adeno-associated virus capsid.
J.Virol., 97, 2023
8EU6
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BU of 8eu6 by Molmil
Acheta domesticus segmented densovirus high buoyancy fraction 1 (HB1) empty capsid structure
Descriptor: Capsid protein
Authors:Penzes, J.J, McKenna, R, Tijssen, P.
Deposit date:2022-10-18
Release date:2022-11-09
Last modified:2025-06-04
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Bipartite genome and structural organization of the parvovirus Acheta domesticus segmented densovirus.
Nat Commun, 14, 2023
8EU7
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BU of 8eu7 by Molmil
Acheta domesticus segmented densovirus VP-ORF1 virus-like particle
Descriptor: Capsid protein
Authors:Penzes, J.J, McKenna, R, Tijssen, P.
Deposit date:2022-10-18
Release date:2022-11-09
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Bipartite genome and structural organization of the parvovirus Acheta domesticus segmented densovirus.
Nat Commun, 14, 2023
8EU5
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BU of 8eu5 by Molmil
Acheta domesticus segmented densovirus high buoyancy fraction 2 empty capsid structure
Descriptor: Capsid protein
Authors:Penzes, J.J, McKenna, R, Tijssen, P.
Deposit date:2022-10-18
Release date:2022-11-09
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural and molecular biology of Acheta domesticus segmented densovirus, the first parvovirus to harbor a bipartite genome
To Be Published
6B4D
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BU of 6b4d by Molmil
Crystal structure of human carbonic anhydrase II in complex with a heteroaryl-pyrazole carboxylic acid derivative.
Descriptor: 3-(1-ethyl-1H-indol-3-yl)-1-methyl-1H-pyrazole-5-carboxylic acid, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ...
Authors:Lomelino, C.L, Mahon, B.P, McKenna, R.
Deposit date:2017-09-26
Release date:2018-02-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.196 Å)
Cite:Exploring Heteroaryl-pyrazole Carboxylic Acids as Human Carbonic Anhydrase XII Inhibitors.
ACS Med Chem Lett, 8, 2017
2ADP
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BU of 2adp by Molmil
Nitrated Human Manganese Superoxide Dismutase
Descriptor: MANGANESE (II) ION, POTASSIUM ION, Superoxide dismutase [Mn]
Authors:Quint, P, Reutzel, R, Mikulski, R, McKenna, R, Silverman, D.N.
Deposit date:2005-07-20
Release date:2006-07-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of nitrated human manganese superoxide dismutase: mechanism of inactivation.
FREE RADIC.BIOL.MED., 40, 2006
2ADQ
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BU of 2adq by Molmil
Human Manganese Superoxide Dismutase
Descriptor: MANGANESE (II) ION, POTASSIUM ION, Superoxide dismutase [Mn]
Authors:Quint, P, Reutzel, R, Mikulski, R, McKenna, R, Silverman, D.N.
Deposit date:2005-07-20
Release date:2006-07-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of nitrated human manganese superoxide dismutase: mechanism of inactivation.
FREE RADIC.BIOL.MED., 40, 2006
4M2V
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BU of 4m2v by Molmil
Genetically engineered Carbonic Anhydrase IX in complex with Brinzolamide
Descriptor: (+)-4-ETHYLAMINO-3,4-DIHYDRO-2-(METHOXY)PROPYL-2H-THIENO[3,2-E]-1,2-THIAZINE-6-SULFONAMIDE-1,1-DIOXIDE, Carbonic anhydrase 2, ZINC ION
Authors:Pinard, M.P, Boone, C.D, Rife, B.D, Supuran, C.T, Mckenna, R.
Deposit date:2013-08-05
Release date:2013-11-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.718 Å)
Cite:Structural study of interaction between brinzolamide and dorzolamide inhibition of human carbonic anhydrases.
Bioorg.Med.Chem., 21, 2013
4M2R
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BU of 4m2r by Molmil
Human Carbonic Anhydrase II in complex with Brinzolamide
Descriptor: (+)-4-ETHYLAMINO-3,4-DIHYDRO-2-(METHOXY)PROPYL-2H-THIENO[3,2-E]-1,2-THIAZINE-6-SULFONAMIDE-1,1-DIOXIDE, Carbonic anhydrase 2, ZINC ION
Authors:Pinard, M.P, Boone, C.D, Rife, B.D, Supuran, C.T, Mckenna, R.
Deposit date:2013-08-05
Release date:2013-11-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.993 Å)
Cite:Structural study of interaction between brinzolamide and dorzolamide inhibition of human carbonic anhydrases.
Bioorg.Med.Chem., 21, 2013
4M2W
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BU of 4m2w by Molmil
Genetically engineered Carbonic Anhydrase IX in complex with Dorzolamide
Descriptor: (4S-TRANS)-4-(ETHYLAMINO)-5,6-DIHYDRO-6-METHYL-4H-THIENO(2,3-B)THIOPYRAN-2-SULFONAMIDE-7,7-DIOXIDE, Carbonic anhydrase 2, ZINC ION
Authors:Pinard, M.P, Boone, C.D, Rife, B.D, Supuran, C.T, McKenna, R.
Deposit date:2013-08-05
Release date:2013-11-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.658 Å)
Cite:Structural study of interaction between brinzolamide and dorzolamide inhibition of human carbonic anhydrases.
Bioorg.Med.Chem., 21, 2013

238582

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