5WLU

Carbonic Anhydrase IX-mimic in complex with aryloxy-2-hydroxypropylammine sulfonamide

Summary for 5WLU

• Entry DOI: 10.2210/pdb5wlu/pdb
• Descriptor: Carbonic Anhydrase IX-mimic, ZINC ION, 4-{(2R)-2-hydroxy-3-[(propan-2-yl)amino]propoxy}-N-[2-(4-sulfamoylphenyl)ethyl]benzamide, ... (4 entities in total)
• Functional Keywords: carbonic anhydrase, beta adrenergic receptor, sulfonamide, aryloxy-2-hydroxypropylammine, lyase, lyase-inhibitor complex, lyase/inhibitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 29345.41

Authors

Lomelino, C.L.,Andring, J.T.,McKenna, R. (deposition date: 2017-07-27, release date: 2018-08-01, Last modification date: 2023-10-04)

• Primary citation: Nocentini, A.,Ceruso, M.,Bua, S.,Lomelino, C.L.,Andring, J.T.,McKenna, R.,Lanzi, C.,Masini, E.,Pecori, R.,Matucci, R.,Filippi, L.,Gratteri, P.,Carta, F.,Selleri, S.,Supuran, C.T.; Hybrids for multitargeted therapy Beta Adrenergic Receptor modulators CAIs; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.39 Å)