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2F4O
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BU of 2f4o by Molmil
The Mouse PNGase-HR23 Complex Reveals a Complete Remodulation of the Protein-Protein Interface Compared to its Yeast Orthologs
Descriptor: CHLORIDE ION, PHQ-VAL-ALA-ASP-CF0, XP-C repair complementing complex 58 kDa protein, ...
Authors:Zhao, G, Zhou, X, Wang, L, Kisker, C, Lennarz, W.J, Schindelin, H.
Deposit date:2005-11-23
Release date:2006-03-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Structure of the mouse peptide N-glycanase-HR23 complex suggests co-evolution of the endoplasmic reticulum-associated degradation and DNA repair pathways.
J.Biol.Chem., 281, 2006
1SFF
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BU of 1sff by Molmil
Structure of gamma-aminobutyrate aminotransferase complex with aminooxyacetate
Descriptor: 1,2-ETHANEDIOL, 4'-DEOXY-4'-ACETYLYAMINO-PYRIDOXAL-5'-PHOSPHATE, 4-aminobutyrate aminotransferase, ...
Authors:Liu, W, Peterson, P.E, Carter, R.J, Zhou, X, Langston, J.A, Fisher, A.J, Toney, M.D.
Deposit date:2004-02-19
Release date:2004-09-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of unbound and aminooxyacetate-bound Escherichia coli gamma-aminobutyrate aminotransferase.
Biochemistry, 43, 2004
1SF2
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BU of 1sf2 by Molmil
Structure of E. coli gamma-aminobutyrate aminotransferase
Descriptor: 1,2-ETHANEDIOL, 4-aminobutyrate aminotransferase, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Liu, W, Peterson, P.E, Carter, R.J, Zhou, X, Langston, J.A, Fisher, A.J, Toney, M.D.
Deposit date:2004-02-19
Release date:2004-09-14
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of unbound and aminooxyacetate-bound Escherichia coli gamma-aminobutyrate aminotransferase.
Biochemistry, 43, 2004
7D5I
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BU of 7d5i by Molmil
Structure of Mycobacterium smegmatis bd complex in the apo-form.
Descriptor: CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, Cytochrome D ubiquinol oxidase subunit 1, HEME B/C, ...
Authors:Wang, W, Gong, H, Gao, Y, Zhou, X, Rao, Z.
Deposit date:2020-09-26
Release date:2021-06-23
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Cryo-EM structure of mycobacterial cytochrome bd reveals two oxygen access channels.
Nat Commun, 12, 2021
8JIX
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BU of 8jix by Molmil
Crystal structure of the Bagaza virus helicase and structure-based discovery of a novel inhibitor
Descriptor: Genome polyprotein
Authors:Zhao, R, Shu, W, Cao, J.M, Zhou, X, Wang, D.P.
Deposit date:2023-05-29
Release date:2024-03-06
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Crystal structure of the Bagaza virus helicase and structure-based discovery of a novel inhibitor
To Be Published
8JED
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BU of 8jed by Molmil
Crystal structure of mRNA cap (guanine-N7) methyltransferase E12 subunit from monkeypox virus and discovery of its inhibitors
Descriptor: mRNA-capping enzyme regulatory subunit OPG124
Authors:Wang, D, Zhao, R, Shu, W, Hu, W, Wang, M, Cao, J, Zhou, X.
Deposit date:2023-05-15
Release date:2023-12-06
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Crystal structure of mRNA cap (guanine-N7) methyltransferase E12 subunit from monkeypox virus and discovery of its inhibitors.
Int.J.Biol.Macromol., 253, 2023
8HUZ
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BU of 8huz by Molmil
the structure of trans-editing factor ProX
Descriptor: Prolyl-tRNA synthetase associated domain-containing protein 1
Authors:Chen, M, Zhou, X.
Deposit date:2022-12-25
Release date:2024-01-17
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:the structure of trans-editing factor ProX
To Be Published
2HPL
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BU of 2hpl by Molmil
Crystal structure of the mouse p97/PNGase complex
Descriptor: C-terminal of mouse p97/VCP, PNGase
Authors:Zhao, G, Zhou, X, Wang, L, Li, G, Lennarz, W, Schindelin, H.
Deposit date:2006-07-17
Release date:2007-05-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Studies on peptide:N-glycanase-p97 interaction suggest that p97 phosphorylation modulates endoplasmic reticulum-associated degradation.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2HPJ
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BU of 2hpj by Molmil
Crystal structure of the PUB domain of mouse PNGase
Descriptor: GLYCEROL, PNGase
Authors:Zhao, G, Zhou, X, Wang, L, Li, G, Lennarz, W, Schindelin, H.
Deposit date:2006-07-17
Release date:2007-05-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Studies on peptide:N-glycanase-p97 interaction suggest that p97 phosphorylation modulates endoplasmic reticulum-associated degradation.
Proc.Natl.Acad.Sci.Usa, 104, 2007
7W2B
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BU of 7w2b by Molmil
The closed conformation of the sigma-1 receptor from Xenopus laevis
Descriptor: GOLD ION, Sigma non-opioid intracellular receptor 1, octyl beta-D-glucopyranoside
Authors:Meng, F, Sun, Z, Zhou, X.
Deposit date:2021-11-23
Release date:2022-03-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.203 Å)
Cite:An open-like conformation of the sigma-1 receptor reveals its ligand entry pathway.
Nat Commun, 13, 2022
7W2C
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BU of 7w2c by Molmil
The closed conformation of the sigma-1 receptor from Xenopus laevis complexed with PRE084
Descriptor: 2-morpholin-4-ylethyl 1-phenylcyclohexane-1-carboxylate, GOLD ION, Sigma non-opioid intracellular receptor 1, ...
Authors:Meng, F, Sun, Z, Zhou, X.
Deposit date:2021-11-23
Release date:2022-03-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.335 Å)
Cite:An open-like conformation of the sigma-1 receptor reveals its ligand entry pathway.
Nat Commun, 13, 2022
7W2E
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BU of 7w2e by Molmil
An open-like conformation of the sigma-1 receptor from Xenopus laevis
Descriptor: Sigma non-opioid intracellular receptor 1
Authors:Meng, F, Sun, Z, Zhou, X.
Deposit date:2021-11-23
Release date:2022-03-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.557 Å)
Cite:An open-like conformation of the sigma-1 receptor reveals its ligand entry pathway.
Nat Commun, 13, 2022
7W2G
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BU of 7w2g by Molmil
An open-like conformation of the sigma-1 receptor from Xenopus laevis complexed with PRE084 by soaking
Descriptor: 2-morpholin-4-ylethyl 1-phenylcyclohexane-1-carboxylate, Sigma non-opioid intracellular receptor 1, octyl beta-D-glucopyranoside
Authors:Meng, F, Sun, Z, Zhou, X.
Deposit date:2021-11-23
Release date:2022-03-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.851 Å)
Cite:An open-like conformation of the sigma-1 receptor reveals its ligand entry pathway.
Nat Commun, 13, 2022
7W2H
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BU of 7w2h by Molmil
A double cysteine variant of the sigma-1 receptor from Xenopus laevis complexed with S1RA
Descriptor: 4-[2-(5-methyl-1-naphthalen-2-yl-pyrazol-3-yl)oxyethyl]morpholine, Sigma non-opioid intracellular receptor 1
Authors:Meng, F, Sun, Z, Zhou, X.
Deposit date:2021-11-23
Release date:2022-03-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.796 Å)
Cite:An open-like conformation of the sigma-1 receptor reveals its ligand entry pathway.
Nat Commun, 13, 2022
7W2D
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BU of 7w2d by Molmil
The closed conformation of the sigma-1 receptor from Xenopus laevis complexed with S1RA
Descriptor: 4-[2-(5-methyl-1-naphthalen-2-yl-pyrazol-3-yl)oxyethyl]morpholine, GOLD ION, Sigma non-opioid intracellular receptor 1
Authors:Meng, F, Sun, Z, Zhou, X.
Deposit date:2021-11-23
Release date:2022-03-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.471 Å)
Cite:An open-like conformation of the sigma-1 receptor reveals its ligand entry pathway.
Nat Commun, 13, 2022
7W2F
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BU of 7w2f by Molmil
An open-like conformation of the sigma-1 receptor from Xenopus laevis complexed with PRE084 by co-crystallization
Descriptor: 2-morpholin-4-ylethyl 1-phenylcyclohexane-1-carboxylate, Sigma non-opioid intracellular receptor 1, octyl beta-D-glucopyranoside
Authors:Meng, F, Sun, Z, Zhou, X.
Deposit date:2021-11-23
Release date:2022-03-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:An open-like conformation of the sigma-1 receptor reveals its ligand entry pathway.
Nat Commun, 13, 2022
7Y5G
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BU of 7y5g by Molmil
Cryo-EM structure of a eukaryotic ZnT8 in the presence of zinc
Descriptor: ZINC ION, Zinc transporter 8
Authors:Zhang, S, Fu, C, Luo, Y, Sun, Z, Su, Z, Zhou, X.
Deposit date:2022-06-17
Release date:2022-12-14
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.85 Å)
Cite:Cryo-EM structure of a eukaryotic zinc transporter at a low pH suggests its Zn 2+ -releasing mechanism.
J.Struct.Biol., 215, 2022
7Y5H
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BU of 7y5h by Molmil
Cryo-EM structure of a eukaryotic ZnT8 at a low pH
Descriptor: ZINC ION, Zinc transporter 8
Authors:Zhang, S, Fu, C, Luo, Y, Sun, Z, Su, Z, Zhou, X.
Deposit date:2022-06-17
Release date:2022-12-14
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:Cryo-EM structure of a eukaryotic zinc transporter at a low pH suggests its Zn 2+ -releasing mechanism.
J.Struct.Biol., 215, 2022
7WD4
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BU of 7wd4 by Molmil
Crystal structure of the Ilheus virus helicase: implications for enzyme function and drug design
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, NS3 helicase
Authors:Wang, D.P, Wang, M.Y, Zhou, X, Wang, W.M, Cao, J.M.
Deposit date:2021-12-21
Release date:2023-01-25
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of the Ilheus virus helicase: implications for enzyme function and drug design
To Be Published
7WXI
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BU of 7wxi by Molmil
GPR domain of Drosophila P5CS filament with glutamate and ATPgammaS
Descriptor: Delta-1-pyrroline-5-carboxylate synthase, GAMMA-GLUTAMYL PHOSPHATE
Authors:Liu, J.L, Zhong, J, Guo, C.J, Zhou, X.
Deposit date:2022-02-14
Release date:2022-03-30
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis of dynamic P5CS filaments.
Elife, 11, 2022
7WXH
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BU of 7wxh by Molmil
GPR domain open form of Drosophila P5CS filament with glutamate, ATP, and NADPH
Descriptor: Delta-1-pyrroline-5-carboxylate synthase
Authors:Liu, J.L, Zhong, J, Guo, C.J, Zhou, X.
Deposit date:2022-02-14
Release date:2022-03-30
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural basis of dynamic P5CS filaments.
Elife, 11, 2022
7WX4
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BU of 7wx4 by Molmil
GK domain of Drosophila P5CS filament with glutamate and ATPgammaS
Descriptor: Delta-1-pyrroline-5-carboxylate synthase
Authors:Liu, J.L, Zhong, J, Guo, C.J, Zhou, X.
Deposit date:2022-02-14
Release date:2022-04-06
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of dynamic P5CS filaments.
Elife, 11, 2022
7WXG
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BU of 7wxg by Molmil
GPR domain closed form of Drosophila P5CS filament with glutamate, ATP, and NADPH
Descriptor: Delta-1-pyrroline-5-carboxylate synthase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Liu, J.L, Zhong, J, Guo, C.J, Zhou, X.
Deposit date:2022-02-14
Release date:2022-03-30
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis of dynamic P5CS filaments.
Elife, 11, 2022
7WXF
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BU of 7wxf by Molmil
GPR domain of Drosophila P5CS filament with glutamate
Descriptor: Delta-1-pyrroline-5-carboxylate synthase
Authors:Liu, J.L, Zhong, J, Guo, C.J, Zhou, X.
Deposit date:2022-02-14
Release date:2022-03-30
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis of dynamic P5CS filaments.
Elife, 11, 2022
7WX3
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BU of 7wx3 by Molmil
GK domain of Drosophila P5CS filament with glutamate, ATP, and NADPH
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Delta-1-pyrroline-5-carboxylate synthase, GAMMA-GLUTAMYL PHOSPHATE, ...
Authors:Liu, J.L, Zhong, J, Guo, C.J, Zhou, X.
Deposit date:2022-02-14
Release date:2022-04-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of dynamic P5CS filaments.
Elife, 11, 2022

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