7W2H
A double cysteine variant of the sigma-1 receptor from Xenopus laevis complexed with S1RA
Summary for 7W2H
Entry DOI | 10.2210/pdb7w2h/pdb |
Descriptor | Sigma non-opioid intracellular receptor 1, 4-[2-(5-methyl-1-naphthalen-2-yl-pyrazol-3-yl)oxyethyl]morpholine (2 entities in total) |
Functional Keywords | sigma receptor, membrane receptor, s1r, ligand entry, membrane protein |
Biological source | Xenopus laevis (African clawed frog) |
Total number of polymer chains | 24 |
Total formula weight | 609674.64 |
Authors | |
Primary citation | Meng, F.,Xiao, Y.,Ji, Y.,Sun, Z.,Zhou, X. An open-like conformation of the sigma-1 receptor reveals its ligand entry pathway. Nat Commun, 13:1267-1267, 2022 Cited by PubMed: 35273182DOI: 10.1038/s41467-022-28946-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.796 Å) |
Structure validation
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