7W2H

A double cysteine variant of the sigma-1 receptor from Xenopus laevis complexed with S1RA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005634	cellular_component	nucleus
A	0005635	cellular_component	nuclear envelope
A	0005637	cellular_component	nuclear inner membrane
A	0005640	cellular_component	nuclear outer membrane
A	0005783	cellular_component	endoplasmic reticulum
A	0005789	cellular_component	endoplasmic reticulum membrane
A	0006869	biological_process	lipid transport
A	0016020	cellular_component	membrane
A	0031410	cellular_component	cytoplasmic vesicle
B	0005634	cellular_component	nucleus
B	0005635	cellular_component	nuclear envelope
B	0005637	cellular_component	nuclear inner membrane
B	0005640	cellular_component	nuclear outer membrane
B	0005783	cellular_component	endoplasmic reticulum
B	0005789	cellular_component	endoplasmic reticulum membrane
B	0006869	biological_process	lipid transport
B	0016020	cellular_component	membrane
B	0031410	cellular_component	cytoplasmic vesicle
C	0005634	cellular_component	nucleus
C	0005635	cellular_component	nuclear envelope
C	0005637	cellular_component	nuclear inner membrane
C	0005640	cellular_component	nuclear outer membrane
C	0005783	cellular_component	endoplasmic reticulum
C	0005789	cellular_component	endoplasmic reticulum membrane
C	0006869	biological_process	lipid transport
C	0016020	cellular_component	membrane
C	0031410	cellular_component	cytoplasmic vesicle
D	0005634	cellular_component	nucleus
D	0005635	cellular_component	nuclear envelope
D	0005637	cellular_component	nuclear inner membrane
D	0005640	cellular_component	nuclear outer membrane
D	0005783	cellular_component	endoplasmic reticulum
D	0005789	cellular_component	endoplasmic reticulum membrane
D	0006869	biological_process	lipid transport
D	0016020	cellular_component	membrane
D	0031410	cellular_component	cytoplasmic vesicle
E	0005634	cellular_component	nucleus
E	0005635	cellular_component	nuclear envelope
E	0005637	cellular_component	nuclear inner membrane
E	0005640	cellular_component	nuclear outer membrane
E	0005783	cellular_component	endoplasmic reticulum
E	0005789	cellular_component	endoplasmic reticulum membrane
E	0006869	biological_process	lipid transport
E	0016020	cellular_component	membrane
E	0031410	cellular_component	cytoplasmic vesicle
F	0005634	cellular_component	nucleus
F	0005635	cellular_component	nuclear envelope
F	0005637	cellular_component	nuclear inner membrane
F	0005640	cellular_component	nuclear outer membrane
F	0005783	cellular_component	endoplasmic reticulum
F	0005789	cellular_component	endoplasmic reticulum membrane
F	0006869	biological_process	lipid transport
F	0016020	cellular_component	membrane
F	0031410	cellular_component	cytoplasmic vesicle
G	0005634	cellular_component	nucleus
G	0005635	cellular_component	nuclear envelope
G	0005637	cellular_component	nuclear inner membrane
G	0005640	cellular_component	nuclear outer membrane
G	0005783	cellular_component	endoplasmic reticulum
G	0005789	cellular_component	endoplasmic reticulum membrane
G	0006869	biological_process	lipid transport
G	0016020	cellular_component	membrane
G	0031410	cellular_component	cytoplasmic vesicle
H	0005634	cellular_component	nucleus
H	0005635	cellular_component	nuclear envelope
H	0005637	cellular_component	nuclear inner membrane
H	0005640	cellular_component	nuclear outer membrane
H	0005783	cellular_component	endoplasmic reticulum
H	0005789	cellular_component	endoplasmic reticulum membrane
H	0006869	biological_process	lipid transport
H	0016020	cellular_component	membrane
H	0031410	cellular_component	cytoplasmic vesicle
I	0005634	cellular_component	nucleus
I	0005635	cellular_component	nuclear envelope
I	0005637	cellular_component	nuclear inner membrane
I	0005640	cellular_component	nuclear outer membrane
I	0005783	cellular_component	endoplasmic reticulum
I	0005789	cellular_component	endoplasmic reticulum membrane
I	0006869	biological_process	lipid transport
I	0016020	cellular_component	membrane
I	0031410	cellular_component	cytoplasmic vesicle
J	0005634	cellular_component	nucleus
J	0005635	cellular_component	nuclear envelope
J	0005637	cellular_component	nuclear inner membrane
J	0005640	cellular_component	nuclear outer membrane
J	0005783	cellular_component	endoplasmic reticulum
J	0005789	cellular_component	endoplasmic reticulum membrane
J	0006869	biological_process	lipid transport
J	0016020	cellular_component	membrane
J	0031410	cellular_component	cytoplasmic vesicle
K	0005634	cellular_component	nucleus
K	0005635	cellular_component	nuclear envelope
K	0005637	cellular_component	nuclear inner membrane
K	0005640	cellular_component	nuclear outer membrane
K	0005783	cellular_component	endoplasmic reticulum
K	0005789	cellular_component	endoplasmic reticulum membrane
K	0006869	biological_process	lipid transport
K	0016020	cellular_component	membrane
K	0031410	cellular_component	cytoplasmic vesicle
L	0005634	cellular_component	nucleus
L	0005635	cellular_component	nuclear envelope
L	0005637	cellular_component	nuclear inner membrane
L	0005640	cellular_component	nuclear outer membrane
L	0005783	cellular_component	endoplasmic reticulum
L	0005789	cellular_component	endoplasmic reticulum membrane
L	0006869	biological_process	lipid transport
L	0016020	cellular_component	membrane
L	0031410	cellular_component	cytoplasmic vesicle
M	0005634	cellular_component	nucleus
M	0005635	cellular_component	nuclear envelope
M	0005637	cellular_component	nuclear inner membrane
M	0005640	cellular_component	nuclear outer membrane
M	0005783	cellular_component	endoplasmic reticulum
M	0005789	cellular_component	endoplasmic reticulum membrane
M	0006869	biological_process	lipid transport
M	0016020	cellular_component	membrane
M	0031410	cellular_component	cytoplasmic vesicle
N	0005634	cellular_component	nucleus
N	0005635	cellular_component	nuclear envelope
N	0005637	cellular_component	nuclear inner membrane
N	0005640	cellular_component	nuclear outer membrane
N	0005783	cellular_component	endoplasmic reticulum
N	0005789	cellular_component	endoplasmic reticulum membrane
N	0006869	biological_process	lipid transport
N	0016020	cellular_component	membrane
N	0031410	cellular_component	cytoplasmic vesicle
O	0005634	cellular_component	nucleus
O	0005635	cellular_component	nuclear envelope
O	0005637	cellular_component	nuclear inner membrane
O	0005640	cellular_component	nuclear outer membrane
O	0005783	cellular_component	endoplasmic reticulum
O	0005789	cellular_component	endoplasmic reticulum membrane
O	0006869	biological_process	lipid transport
O	0016020	cellular_component	membrane
O	0031410	cellular_component	cytoplasmic vesicle
P	0005634	cellular_component	nucleus
P	0005635	cellular_component	nuclear envelope
P	0005637	cellular_component	nuclear inner membrane
P	0005640	cellular_component	nuclear outer membrane
P	0005783	cellular_component	endoplasmic reticulum
P	0005789	cellular_component	endoplasmic reticulum membrane
P	0006869	biological_process	lipid transport
P	0016020	cellular_component	membrane
P	0031410	cellular_component	cytoplasmic vesicle
Q	0005634	cellular_component	nucleus
Q	0005635	cellular_component	nuclear envelope
Q	0005637	cellular_component	nuclear inner membrane
Q	0005640	cellular_component	nuclear outer membrane
Q	0005783	cellular_component	endoplasmic reticulum
Q	0005789	cellular_component	endoplasmic reticulum membrane
Q	0006869	biological_process	lipid transport
Q	0016020	cellular_component	membrane
Q	0031410	cellular_component	cytoplasmic vesicle
R	0005634	cellular_component	nucleus
R	0005635	cellular_component	nuclear envelope
R	0005637	cellular_component	nuclear inner membrane
R	0005640	cellular_component	nuclear outer membrane
R	0005783	cellular_component	endoplasmic reticulum
R	0005789	cellular_component	endoplasmic reticulum membrane
R	0006869	biological_process	lipid transport
R	0016020	cellular_component	membrane
R	0031410	cellular_component	cytoplasmic vesicle
S	0005634	cellular_component	nucleus
S	0005635	cellular_component	nuclear envelope
S	0005637	cellular_component	nuclear inner membrane
S	0005640	cellular_component	nuclear outer membrane
S	0005783	cellular_component	endoplasmic reticulum
S	0005789	cellular_component	endoplasmic reticulum membrane
S	0006869	biological_process	lipid transport
S	0016020	cellular_component	membrane
S	0031410	cellular_component	cytoplasmic vesicle
T	0005634	cellular_component	nucleus
T	0005635	cellular_component	nuclear envelope
T	0005637	cellular_component	nuclear inner membrane
T	0005640	cellular_component	nuclear outer membrane
T	0005783	cellular_component	endoplasmic reticulum
T	0005789	cellular_component	endoplasmic reticulum membrane
T	0006869	biological_process	lipid transport
T	0016020	cellular_component	membrane
T	0031410	cellular_component	cytoplasmic vesicle
U	0005634	cellular_component	nucleus
U	0005635	cellular_component	nuclear envelope
U	0005637	cellular_component	nuclear inner membrane
U	0005640	cellular_component	nuclear outer membrane
U	0005783	cellular_component	endoplasmic reticulum
U	0005789	cellular_component	endoplasmic reticulum membrane
U	0006869	biological_process	lipid transport
U	0016020	cellular_component	membrane
U	0031410	cellular_component	cytoplasmic vesicle
V	0005634	cellular_component	nucleus
V	0005635	cellular_component	nuclear envelope
V	0005637	cellular_component	nuclear inner membrane
V	0005640	cellular_component	nuclear outer membrane
V	0005783	cellular_component	endoplasmic reticulum
V	0005789	cellular_component	endoplasmic reticulum membrane
V	0006869	biological_process	lipid transport
V	0016020	cellular_component	membrane
V	0031410	cellular_component	cytoplasmic vesicle
W	0005634	cellular_component	nucleus
W	0005635	cellular_component	nuclear envelope
W	0005637	cellular_component	nuclear inner membrane
W	0005640	cellular_component	nuclear outer membrane
W	0005783	cellular_component	endoplasmic reticulum
W	0005789	cellular_component	endoplasmic reticulum membrane
W	0006869	biological_process	lipid transport
W	0016020	cellular_component	membrane
W	0031410	cellular_component	cytoplasmic vesicle
X	0005634	cellular_component	nucleus
X	0005635	cellular_component	nuclear envelope
X	0005637	cellular_component	nuclear inner membrane
X	0005640	cellular_component	nuclear outer membrane
X	0005783	cellular_component	endoplasmic reticulum
X	0005789	cellular_component	endoplasmic reticulum membrane
X	0006869	biological_process	lipid transport
X	0016020	cellular_component	membrane
X	0031410	cellular_component	cytoplasmic vesicle

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	264
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"UniProtKB","id":"Q99720","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	168
Details	Region: {"description":"Important for ligand-binding","evidences":[{"source":"UniProtKB","id":"Q60492","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	48
Details	Site: {"description":"Important for ligand binding","evidences":[{"source":"UniProtKB","id":"Q99720","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---