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5IF9
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BU of 5if9 by Molmil
Crystal Structure of Cobyrinic Acid a,c-diamide synthase from Mycobacterium smegmatis with bound ATP analog and Magnesium
Descriptor: Cobyrinic Acid a,c-diamide synthase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2016-02-25
Release date:2016-03-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Cobyrinic Acid a,c-diamide synthase from Mycobacterium smegmatis with bound ATP analog and Magnesium
TO BE PUBLISHED
5IHP
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BU of 5ihp by Molmil
Crystal Structure of Cobyrinic Acid a,c-diamide synthase from Mycobacterium smegmatis with bound ADP and Magnesium
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cobyrinic Acid a,c-diamide synthase, MAGNESIUM ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2016-02-29
Release date:2016-03-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of Cobyrinic Acid a,c-diamide synthase from Mycobacterium smegmatis with bound ATP analog and Magnesium
TO BE PUBLISHED
3EZN
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BU of 3ezn by Molmil
Crystal structure of phosphoglyceromutase from burkholderia pseudomallei 1710b
Descriptor: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, TETRAETHYLENE GLYCOL
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2008-10-23
Release date:2008-11-11
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:An ensemble of structures of Burkholderia pseudomallei 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase.
Acta Crystallogr.,Sect.F, 67, 2011
3FDZ
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BU of 3fdz by Molmil
Crystal structure of phosphoglyceromutase from burkholderia pseudomallei 1710b with bound 2,3-diphosphoglyceric acid and 3-phosphoglyceric acid
Descriptor: (2R)-2,3-diphosphoglyceric acid, 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, 3-PHOSPHOGLYCERIC ACID, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2008-11-26
Release date:2009-01-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:An ensemble of structures of Burkholderia pseudomallei 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase.
Acta Crystallogr.,Sect.F, 67, 2011
6UH2
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BU of 6uh2 by Molmil
Crystal Structure of Short Chain Dehydrogenase from Leptospira borgpetersenii serovar Hardjo-bovis (Strain JB197) with bound NAD+
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Short chain dehydrogenase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-09-26
Release date:2019-10-09
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:TBD
TO BE PUBLISHED
5MW6
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BU of 5mw6 by Molmil
Crystal structure of the BCL6 BTB-domain with compound 1
Descriptor: 5-chloranyl-~{N}-(4-chlorophenyl)-2-(3,5-dimethylpyrazol-1-yl)pyrimidin-4-amine, B-cell lymphoma 6 protein
Authors:Davies, D.R, Kessler, D.
Deposit date:2017-01-18
Release date:2017-10-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6.
Cell Rep, 20, 2017
4PFS
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BU of 4pfs by Molmil
Crystal Structure of Cobyrinic Acid a,c-diamide synthase from Mycobacterium smegmatis
Descriptor: Cobyrinic Acid a,c-diamide synthase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2014-04-30
Release date:2014-05-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of Cobyrinic Acid a,c-diamide synthase from Mycobacterium smegmatis
TO BE PUBLISHED
6OVI
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BU of 6ovi by Molmil
Crystal Structure of KDPG Aldolase from Legionella Pneumophila with pyruvate captured at low pH as a covalent carbinolamine intermediate
Descriptor: 1,2-ETHANEDIOL, 2,2-bis(oxidanyl)propanoic acid, Keto-deoxy-phosphogluconate aldolase, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-05-07
Release date:2019-06-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structure of KDPG Aldolase from Legionella Pneumophila with pyruvate captured at low pH as a covalent carbinolamine intermediate
To Be Published
6AUB
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BU of 6aub by Molmil
CRYSTAL STRUCTURE OF BRUTON'S TYROSINE KINASE IN COMPLEX WITH INHIBITOR CGI2815
Descriptor: 4-tert-butyl-N-[2-methyl-3-(1-methyl-5-{[5-(morpholine-4-carbonyl)pyridin-2-yl]amino}-6-oxo-1,6-dihydropyridin-3-yl)phenyl]benzamide, SULFATE ION, Tyrosine-protein kinase BTK
Authors:Davies, D.R, Staker, B.L.
Deposit date:2017-08-31
Release date:2018-09-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:To Be Determined
TO BE PUBLISHED
6AUA
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BU of 6aua by Molmil
CRYSTAL STRUCTURE OF BRUTON'S TYROSINE KINASE IN COMPLEX WITH INHIBITOR CGI2625
Descriptor: GLYCEROL, N-{3-[(2R)-6-{[3-amino-4-(morpholine-4-carbonyl)phenyl]amino}-5-oxo-2,5-dihydropyrazin-2-yl]-2-methylphenyl}-4-(piperidin-1-yl)benzamide, SULFATE ION, ...
Authors:Davies, D.R, Staker, B.L.
Deposit date:2017-08-31
Release date:2018-09-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:To Be Determined
TO BE PUBLISHED
4MI2
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BU of 4mi2 by Molmil
Crystal structure of putative Enoyl-CoA hydratase/isomerase from Mycobacterium abscessus
Descriptor: Putative enoyl-CoA hydratase/isomerase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2013-08-30
Release date:2013-09-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of putative Enoyl-CoA hydratase/isomerase from Mycobacterium abscessus
To be Published
6MJ9
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BU of 6mj9 by Molmil
CRYSTAL STRUCTURE OF UBIQUITIN-CONJUGATING ENZYME FROM NAEGLERIA FOWLERI, APO FORM
Descriptor: Ubiquitin-conjugating enzyme
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-09-20
Release date:2018-10-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:CRYSTAL STRUCTURE OF UBIQUITIN-CONJUGATING ENZYME FROM NAEGLERIA FOWLERI, APO FORM
To Be Published
3LNT
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BU of 3lnt by Molmil
Crystal structure of phosphoglyceromutase from Burkholderia Pseudomallei 1710B with bound malonic acid
Descriptor: 1,2-ETHANEDIOL, 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, MALONATE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2010-02-03
Release date:2010-02-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:An ensemble of structures of Burkholderia pseudomallei 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase.
Acta Crystallogr.,Sect.F, 67, 2011
6NB2
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BU of 6nb2 by Molmil
CRYSTAL STRUCTURE OF ENOLASE FROM LEGIONELLA PNEUMOPHILA BOUND TO 2-PHOSPHOGLYCERIC ACID AND MAGNESIUM
Descriptor: 1,2-ETHANEDIOL, 2-PHOSPHOGLYCERIC ACID, Enolase, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-01-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:CRYSTAL STRUCTURE OF ENOLASE FROM LEGIONELLA PNEUMOPHILA BOUND TO 2-PHOSPHOGLYCERIC ACID AND MAGNESIUM
To Be Published
6NBM
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BU of 6nbm by Molmil
CRYSTAL STRUCTURE OF ENOLASE FROM LEGIONELLA PNEUMOPHILA BOUND TO PHOSPHATE AND MAGNESIUM
Descriptor: Enolase, MAGNESIUM ION, PHOSPHATE ION
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-07
Release date:2019-01-09
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:CRYSTAL STRUCTURE OF ENOLASE FROM LEGIONELLA PNEUMOPHILA BOUND TO PHOSPHATE AND MAGNESIUM
To Be Published
6CWA
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BU of 6cwa by Molmil
CRYSTAL STRUCTURE PHGDH IN COMPLEX WITH NADH AND 3-PHOSPHOGLYCERATE AT 1.77 A RESOLUTION
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 3-PHOSPHOGLYCERIC ACID, D-3-phosphoglycerate dehydrogenase
Authors:Davies, D.R, Edwards, T.E.
Deposit date:2018-03-30
Release date:2019-08-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Intracellular Trapping of the Selective Phosphoglycerate Dehydrogenase (PHGDH) InhibitorBI-4924Disrupts Serine Biosynthesis.
J.Med.Chem., 62, 2019
7UMP
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BU of 7ump by Molmil
CRYSTAL STRUCTURE OF PHD2 CATALYTIC DOMAIN (CID 7465) IN COMPLEX WITH AKB-6548 AT 1.8 A RESOLUTION
Descriptor: 1,2-ETHANEDIOL, Egl nine homolog 1, FE (II) ION, ...
Authors:Davie, D.R, Abendroth, J, Boyd, J.
Deposit date:2022-04-07
Release date:2022-05-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Preclinical Characterization of Vadadustat (AKB-6548), an Oral Small Molecule Hypoxia-Inducible Factor Prolyl-4-Hydroxylase Inhibitor, for the Potential Treatment of Renal Anemia.
J.Pharmacol.Exp.Ther., 383, 2022
3K14
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BU of 3k14 by Molmil
Co-crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei with FOL fragment 535, ethyl 3-methyl-5,6-dihydroimidazo[2,1-b][1,3]thiazole-2-carboxylate
Descriptor: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ACETATE ION, CHLORIDE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2009-09-25
Release date:2009-10-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei.
J Struct Funct Genomics, 12, 2011
4TVI
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BU of 4tvi by Molmil
X-ray crystal structure of an aminotransferase from Brucella abortus bound to the co-factor PLP
Descriptor: 1,2-ETHANEDIOL, Aminotransferase, class IV
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2014-06-27
Release date:2014-07-30
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray crystal structure of an aminotransferase from Brucella abortus bound to the co-factor PLP
To Be Published
1BKS
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BU of 1bks by Molmil
TRYPTOPHAN SYNTHASE (E.C.4.2.1.20) FROM SALMONELLA TYPHIMURIUM
Descriptor: PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, TRYPTOPHAN SYNTHASE
Authors:Hyde, C.C.
Deposit date:1998-07-10
Release date:1999-03-23
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Exchange of K+ or Cs+ for Na+ induces local and long-range changes in the three-dimensional structure of the tryptophan synthase alpha2beta2 complex.
Biochemistry, 35, 1996
7S5M
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BU of 7s5m by Molmil
Crystal Structure of a 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase from Mycobacterium smegmatis
Descriptor: 8-amino-7-oxononanoate synthase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2021-09-10
Release date:2021-09-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal Structure of a 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase from Mycobacterium smegmatis
to be published
4W65
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BU of 4w65 by Molmil
Crystal Structure of Glycosyl hydrolase family protein from Mycobacterium fortuitum
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Glycosyl hydrolase family protein
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2014-08-20
Release date:2014-09-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Crystal Structure of Glycosyl hydrolase family protein (Rv0315 ortholog) from Mycobacterium fortuitum
TO BE PUBLISHED
1BL0
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BU of 1bl0 by Molmil
MULTIPLE ANTIBIOTIC RESISTANCE PROTEIN (MARA)/DNA COMPLEX
Descriptor: DNA (5'-D(*CP*CP*GP*AP*TP*GP*CP*CP*AP*CP*GP*TP*TP*TP*TP*GP*CP*TP*AP*AP*AP*TP* CP*C)-3'), DNA (5'-D(*GP*GP*GP*GP*AP*TP*TP*TP*AP*GP*CP*AP*AP*AP*AP*CP*GP*TP*GP*GP*CP*AP* TP*C)-3'), PROTEIN (MULTIPLE ANTIBIOTIC RESISTANCE PROTEIN)
Authors:Davies, S, Rhee, R.G, Martin, J.L, Rosner, D.R.
Deposit date:1998-07-22
Release date:1998-09-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A novel DNA-binding motif in MarA: the first structure for an AraC family transcriptional activator.
Proc.Natl.Acad.Sci.USA, 95, 1998
5K0T
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BU of 5k0t by Molmil
Crystal structure of methionyl-tRNA synthetase MetRS from Brucella melitensis in complex with inhibitor Chem 1415
Descriptor: 1,2-ETHANEDIOL, 1-{3-[(3-chloro-5-methoxybenzyl)amino]propyl}-3-phenylurea, Methionine--tRNA ligase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2016-05-17
Release date:2016-05-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis.
Plos One, 11, 2016
5K0S
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BU of 5k0s by Molmil
Crystal structure of methionyl-tRNA synthetase MetRS from Brucella melitensis in complex with inhibitor Chem 1312
Descriptor: 2-({3-[(3,5-dichlorobenzyl)amino]propyl}amino)quinolin-4(1H)-one, Methionine--tRNA ligase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2016-05-17
Release date:2016-05-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis.
Plos One, 11, 2016

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