8TOX
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1A8Y
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![BU of 1a8y by Molmil](/molmil-images/mine/1a8y) | CRYSTAL STRUCTURE OF CALSEQUESTRIN FROM RABBIT SKELETAL MUSCLE SARCOPLASMIC RETICULUM AT 2.4 A RESOLUTION | Descriptor: | CALSEQUESTRIN | Authors: | Wang, S, Trumble, W.R, Liao, H, Wesson, C.R, Dunker, A.K, Kang, C. | Deposit date: | 1998-03-31 | Release date: | 1999-03-30 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of calsequestrin from rabbit skeletal muscle sarcoplasmic reticulum. Nat.Struct.Biol., 5, 1998
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5IIW
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![BU of 5iiw by Molmil](/molmil-images/mine/5iiw) | Corkscrew assembly of SOD1 residues 28-38 without potassium iodide | Descriptor: | Superoxide dismutase [Cu-Zn] | Authors: | Sangwan, S, Zhao, A, Sawaya, M.R, Eisenberg, D. | Deposit date: | 2016-03-01 | Release date: | 2017-06-28 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Atomic structure of a toxic, oligomeric segment of SOD1 linked to amyotrophic lateral sclerosis (ALS). Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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3WAE
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![BU of 3wae by Molmil](/molmil-images/mine/3wae) | X-ray structure of Fe(III)-bicarbonates-ttfbpa, a ferric ion-binding protein from thermus thermophilus HB8 | Descriptor: | BICARBONATE ION, FE (III) ION, IRON ABC TRANSPORTER, ... | Authors: | Wang, S, Ogata, M, Horita, S, Ohtsuka, J, Nagata, K, Tanokura, M. | Deposit date: | 2013-05-02 | Release date: | 2014-05-21 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A novel mode of ferric ion coordination by the periplasmic ferric ion-binding subunit FbpA of an ABC-type iron transporter from Thermus thermophilus HB8. Acta Crystallogr.,Sect.D, 70, 2014
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6AKR
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![BU of 6akr by Molmil](/molmil-images/mine/6akr) | Crystal structure of the PDE4D catalytic domain in complex with osthole | Descriptor: | 7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one, ZINC ION, cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Authors: | Wang, S, Huo, Y.W, Xie, Y. | Deposit date: | 2018-09-03 | Release date: | 2020-02-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.326 Å) | Cite: | Airway relaxation mechanisms and structural basis of osthole for improving lung function in asthma. Sci.Signal., 13, 2020
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6JBR
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![BU of 6jbr by Molmil](/molmil-images/mine/6jbr) | Tps1/UDP/T6P complex | Descriptor: | 6-O-phosphono-alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose, Trehalose-6-phosphate synthase, URIDINE-5'-DIPHOSPHATE | Authors: | Wang, S, Zhao, Y, Wang, D, Liu, J. | Deposit date: | 2019-01-26 | Release date: | 2019-12-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Crystal structures of Magnaporthe oryzae trehalose-6-phosphate synthase (MoTps1) suggest a model for catalytic process of Tps1. Biochem.J., 476, 2019
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6JAK
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![BU of 6jak by Molmil](/molmil-images/mine/6jak) | OtsA apo structure | Descriptor: | Trehalose-6-phosphate synthase | Authors: | Wang, S, Zhao, Y, Wang, D, Liu, J. | Deposit date: | 2019-01-24 | Release date: | 2019-12-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Crystal structures of Magnaporthe oryzae trehalose-6-phosphate synthase (MoTps1) suggest a model for catalytic process of Tps1. Biochem.J., 476, 2019
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6JBI
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![BU of 6jbi by Molmil](/molmil-images/mine/6jbi) | Structure of Tps1 apo structure | Descriptor: | Trehalose-6-phosphate synthase | Authors: | Wang, S, Zhao, Y, Yi, L, Wang, D, Liu, J. | Deposit date: | 2019-01-25 | Release date: | 2019-12-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of Magnaporthe oryzae trehalose-6-phosphate synthase (MoTps1) suggest a model for catalytic process of Tps1. Biochem.J., 476, 2019
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3KQX
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![BU of 3kqx by Molmil](/molmil-images/mine/3kqx) | Structure of a protease 1 | Descriptor: | CARBONATE ION, M17 leucyl aminopeptidase, NONAETHYLENE GLYCOL, ... | Authors: | McGowan, S, Whisstock, J.C. | Deposit date: | 2009-11-17 | Release date: | 2010-02-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases Proc.Natl.Acad.Sci.USA, 107, 2010
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6JBW
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![BU of 6jbw by Molmil](/molmil-images/mine/6jbw) | Structure of Tps1/UDP complex | Descriptor: | Trehalose-6-phosphate synthase, URIDINE-5'-DIPHOSPHATE | Authors: | Wang, S, Zhao, Y, Wang, D, Liu, J. | Deposit date: | 2019-01-26 | Release date: | 2019-12-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Crystal structures of Magnaporthe oryzae trehalose-6-phosphate synthase (MoTps1) suggest a model for catalytic process of Tps1. Biochem.J., 476, 2019
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3KR4
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![BU of 3kr4 by Molmil](/molmil-images/mine/3kr4) | Structure of a protease 3 | Descriptor: | 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, CARBONATE ION, M17 leucyl aminopeptidase, ... | Authors: | McGowan, S, Whisstock, J.C. | Deposit date: | 2009-11-17 | Release date: | 2010-02-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases Proc.Natl.Acad.Sci.USA, 107, 2010
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6CM4
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![BU of 6cm4 by Molmil](/molmil-images/mine/6cm4) | Structure of the D2 Dopamine Receptor Bound to the Atypical Antipsychotic Drug Risperidone | Descriptor: | 3-[2-[4-(6-fluoranyl-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one, D(2) dopamine receptor, endolysin chimera, ... | Authors: | Wang, S, Che, T, Levit, A, Shoichet, B.K, Wacker, D, Roth, B.L. | Deposit date: | 2018-03-02 | Release date: | 2018-03-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.867 Å) | Cite: | Structure of the D2 dopamine receptor bound to the atypical antipsychotic drug risperidone. Nature, 555, 2018
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3KQZ
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![BU of 3kqz by Molmil](/molmil-images/mine/3kqz) | Structure of a protease 2 | Descriptor: | CARBONATE ION, M17 leucyl aminopeptidase, NONAETHYLENE GLYCOL, ... | Authors: | McGowan, S, Whisstock, J.C. | Deposit date: | 2009-11-17 | Release date: | 2010-02-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases Proc.Natl.Acad.Sci.USA, 107, 2010
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3KR5
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![BU of 3kr5 by Molmil](/molmil-images/mine/3kr5) | Structure of a protease 4 | Descriptor: | (2S)-3-[(R)-[(1S)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]-2-benzylpropanoic acid, CARBONATE ION, M17 leucyl aminopeptidase, ... | Authors: | McGowan, S, Whisstock, J.C. | Deposit date: | 2009-11-17 | Release date: | 2010-02-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases Proc.Natl.Acad.Sci.USA, 107, 2010
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2XNB
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![BU of 2xnb by Molmil](/molmil-images/mine/2xnb) | Discovery and Characterisation of 2-Anilino-4-(thiazol-5-yl) pyrimidine Transcriptional CDK Inhibitors as Anticancer Agents | Descriptor: | 3,4-DIMETHYL-5-(2-{[(1Z)-4-PIPERAZIN-1-YLCYCLOHEXA-2,4-DIEN-1-YLIDENE]AMINO}PYRIMIDIN-4-YL)-1,3-THIAZOL-2(3H)-ONE, CELL DIVISION PROTEIN KINASE 2 | Authors: | Wang, S, Griffiths, G, Midgley, C.A, Barnett, A.L, Cooper, M, Grabarek, J, Ingram, L, Jackson, W, Kontopidis, G, McClue, S.J, McInnes, C, McLachlan, J, Meades, C, Mezna, M, Stuart, I, Thomas, M.P, Zheleva, D.I, Lane, D.P, Jackson, R.C, Glover, D.M, Blake, D.G, Fischer, P.M. | Deposit date: | 2010-08-01 | Release date: | 2010-11-10 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Discovery and Characterisation of 2-Anilino-4-(Thiazol-5-Yl)Pyrimidine Transcriptional Cdk Inhibitors as Anticancer Agents Chem.Biol., 17, 2010
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2XMY
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![BU of 2xmy by Molmil](/molmil-images/mine/2xmy) | Discovery and Characterisation of 2-Anilino-4-(thiazol-5-yl) pyrimidine Transcriptional CDK Inhibitors as Anticancer Agents | Descriptor: | 4-[4-(3,4-DIMETHYL-2-OXO-2,3-DIHYDRO-THIAZOL-5-YL)-PYRIMIDIN-2-YLAMINO]-N-(2-METHOXY-ETHYL)-BENZENESULFONAMIDE, CELL DIVISION PROTEIN KINASE 2 | Authors: | Wang, S, Griffiths, G, Midgley, C.A, Barnett, A.L, Cooper, M, Grabarek, J, Ingram, L, Jackson, W, Kontopidis, G, McClue, S.J, McInnes, C, McLachlan, J, Meades, C, Mezna, M, Stuart, I, Thomas, M.P, Zheleva, D.I, Lane, D.P, Jackson, R.C, Glover, D.M, Blake, D.G, Fischer, P.M. | Deposit date: | 2010-07-29 | Release date: | 2010-11-10 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Discovery and Characterisation of 2-Anilino-4-(Thiazol-5-Yl)Pyrimidine Transcriptional Cdk Inhibitors as Anticancer Agents Chem.Biol., 17, 2010
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1IYB
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8W6L
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4F88
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![BU of 4f88 by Molmil](/molmil-images/mine/4f88) | X-ray Crystal Structure of PlyC | Descriptor: | PlyCA, PlyCB | Authors: | McGowan, S, Buckle, A.M, Fischetti, V.A, Nelson, D.C, Whisstock, J.C. | Deposit date: | 2012-05-17 | Release date: | 2012-07-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | X-ray crystal structure of the streptococcal specific phage lysin PlyC. Proc.Natl.Acad.Sci.USA, 109, 2012
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2MAB
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2MBB
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![BU of 2mbb by Molmil](/molmil-images/mine/2mbb) | Solution Structure of the human Polymerase iota UBM1-Ubiquitin Complex | Descriptor: | Immunoglobulin G-binding protein G/DNA polymerase iota fusion protein, Polyubiquitin-B | Authors: | Wang, S, Zhou, P. | Deposit date: | 2013-07-29 | Release date: | 2014-06-04 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Sparsely-sampled, high-resolution 4-D omit spectra for detection and assignment of intermolecular NOEs of protein complexes. J.Biomol.Nmr, 59, 2014
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3EBG
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![BU of 3ebg by Molmil](/molmil-images/mine/3ebg) | Structure of the M1 Alanylaminopeptidase from malaria | Descriptor: | GLYCEROL, M1 family aminopeptidase, MAGNESIUM ION, ... | Authors: | McGowan, S, Porter, C.J, Buckle, A.M, Whisstock, J.C. | Deposit date: | 2008-08-27 | Release date: | 2009-01-27 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase Proc.Natl.Acad.Sci.USA, 106, 2009
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1VCZ
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![BU of 1vcz by Molmil](/molmil-images/mine/1vcz) | |
2PMU
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![BU of 2pmu by Molmil](/molmil-images/mine/2pmu) | Crystal structure of the DNA-binding domain of PhoP | Descriptor: | CHLORIDE ION, GLYCINE, PHOSPHATE ION, ... | Authors: | Wang, S. | Deposit date: | 2007-04-23 | Release date: | 2008-02-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.779 Å) | Cite: | Structure of the DNA-binding domain of the response regulator PhoP from Mycobacterium tuberculosis Biochemistry, 46, 2007
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3EBI
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![BU of 3ebi by Molmil](/molmil-images/mine/3ebi) | Structure of the M1 Alanylaminopeptidase from malaria complexed with the phosphinate dipeptide analog | Descriptor: | (2S)-3-[(R)-[(1S)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]-2-benzylpropanoic acid, GLYCEROL, M1 family aminopeptidase, ... | Authors: | McGowan, S, Porter, C.J, Buckle, A.M, Whisstock, J.C. | Deposit date: | 2008-08-27 | Release date: | 2009-01-27 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase Proc.Natl.Acad.Sci.USA, 106, 2009
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