4NPU
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4NPT
| Crystal Structure of HIV-1 Protease Multiple Mutant P51 Complexed with Darunavir | Descriptor: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, GLYCEROL, Protease | Authors: | Zhang, Y, Weber, I.T. | Deposit date: | 2013-11-22 | Release date: | 2014-10-08 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Structures of darunavir-resistant HIV-1 protease mutant reveal atypical binding of darunavir to wide open flaps. Acs Chem.Biol., 9, 2014
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6LPI
| Crystal Structure of AHAS holo-enzyme | Descriptor: | Acetolactate synthase isozyme 1 large subunit, Acetolactate synthase isozyme 1 small subunit, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Zhang, Y, Yang, X, Xi, Z, Shen, Y. | Deposit date: | 2020-01-10 | Release date: | 2020-11-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.849 Å) | Cite: | Molecular architecture of the acetohydroxyacid synthase holoenzyme. Biochem.J., 477, 2020
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6MG8
| Structural basis for cholesterol transport-like activity of the Hedgehog receptor Patched | Descriptor: | CHOLESTEROL, Protein patched homolog 1 | Authors: | Zhang, Y, Bulkley, D, Xin, Y, Roberts, K.J, Asarnow, D.E, Sharma, A, Myers, B.R, Cho, W, Cheng, Y, Beachy, P.A. | Deposit date: | 2018-09-13 | Release date: | 2018-11-28 | Last modified: | 2022-03-16 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural Basis for Cholesterol Transport-like Activity of the Hedgehog Receptor Patched. Cell, 175, 2018
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5VTM
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9ATN
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2MNY
| NMR Structure of KDM5B PHD1 finger | Descriptor: | Lysine-specific demethylase 5B, ZINC ION | Authors: | Zhang, Y, Yang, H.R, Guo, X, Rong, N.Y, Song, Y.J, Xu, Y.W, Lan, W.X, Xu, Y.H, Cao, C. | Deposit date: | 2014-04-16 | Release date: | 2014-08-06 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The PHD1 finger of KDM5B recognizes unmodified H3K4 during the demethylation of histone H3K4me2/3 by KDM5B. Protein Cell, 5, 2014
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2MNZ
| NMR Structure of KDM5B PHD1 finger in complex with H3K4me0(1-10aa) | Descriptor: | H3K4me0, Lysine-specific demethylase 5B, ZINC ION | Authors: | Zhang, Y, Yang, H.R, Guo, X, Rong, N.Y, Song, Y.J, Xu, Y.W, Lan, W.X, Xu, Y.H, Cao, C. | Deposit date: | 2014-04-16 | Release date: | 2014-08-06 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The PHD1 finger of KDM5B recognizes unmodified H3K4 during the demethylation of histone H3K4me2/3 by KDM5B. Protein Cell, 5, 2014
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5M5G
| Crystal structure of the Chaetomium Thermophilum polycomb repressive complex 2 (PRC2) | Descriptor: | Fragment from molecular 2 (region containing putative polycomb protein Suz12), HISTONE H3 11-Mer peptide, Putative uncharacterized protein, ... | Authors: | Zhang, Y, Justin, N, Wilson, J, Gamblin, S. | Deposit date: | 2016-10-21 | Release date: | 2017-01-11 | Last modified: | 2019-10-16 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Comment on "Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2". Science, 354, 2016
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5E00
| Structure of HLA-A2 P130 | Descriptor: | Beta-2-microglobulin, GLY-VAL-TRP-ILE-ARG-THR-PRO-PRO-ALA, HLA class I histocompatibility antigen, ... | Authors: | Zhang, Y, Wu, Y, Qi, J, Liu, J, Gao, G.F, Meng, S. | Deposit date: | 2015-09-26 | Release date: | 2017-01-18 | Last modified: | 2019-01-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | CD8+T-Cell Response-Associated Evolution of Hepatitis B Virus Core Protein and Disease Progress. J. Virol., 92, 2018
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9CIL
| Crystal structure of Staphylococcal nuclease variant Delta+PHS T41V/S59A at cryogenic temperature | Descriptor: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | Authors: | Zhang, Y, Schlessman, J.L, Siegler, M.A, Garcia-Moreno E, B. | Deposit date: | 2024-07-03 | Release date: | 2024-08-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of Staphylococcal nuclease variant Delta+PHS T41V/S59A at cryogenic temperature To Be Published
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9CII
| Crystal structure of Staphylococcal nuclease variant Delta+PHS V23D/L36R at cryogenic temperature | Descriptor: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | Authors: | Zhang, Y, Schlessman, J.L, Robinson, A.C, Garcia-Moreno E, B. | Deposit date: | 2024-07-03 | Release date: | 2024-08-07 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of Staphylococcal nuclease variant Delta+PHS V23D/L36R at cryogenic temperature To Be Published
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9CIJ
| Crystal structure of Staphylococcal nuclease variant Delta+PHS V23E/L36R at cryogenic temperature | Descriptor: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | Authors: | Zhang, Y, Schlessman, L.J, Siegler, M.A, Garcia-Moreno E, B. | Deposit date: | 2024-07-03 | Release date: | 2024-08-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of Staphylococcal nuclease variant Delta+PHS V23E/L36R at cryogenic temperature To Be Published
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9CIK
| Crystal structure of Staphylococcal nuclease variant Delta+PHS V23R/L36D at cryogenic temperature | Descriptor: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | Authors: | Zhang, Y, Schlessman, J.L, SIegler, M.A, Garcia-Moreno E, B. | Deposit date: | 2024-07-03 | Release date: | 2024-08-07 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of Staphylococcal nuclease variant Delta+PHS V23R/L36D at cryogenic temperature To Be Published
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9CU9
| Crystal structure of Staphylococcal nuclease variant Delta+PHS V23D/L36K at cryogenic temperature | Descriptor: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | Authors: | Zhang, Y, Schlessman, J.L, Robinson, A.C, Garcia-Moreno E, B. | Deposit date: | 2024-07-26 | Release date: | 2024-08-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of Staphylococcal nuclease variant Delta+PHS V23D/L36K at cryogenic temperature To Be Published
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9C11
| Crystal structure of Staphylococcal nuclease variant Delta+PHS L36R at cryogenic temperature | Descriptor: | CALCIUM ION, Nuclease A, THYMIDINE-3',5'-DIPHOSPHATE | Authors: | Zhang, Y, Schlessman, J.L, Siegler, M.A, Garcia-Moreno E, B. | Deposit date: | 2024-05-28 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Domain-swapping promoted by the introduction of a charge in the hydrophobic interior of a protein To Be Published
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7ST4
| Calcium-saturated jGCaMP8.410.80 | Descriptor: | CALCIUM ION, GLYCEROL, L(+)-TARTARIC ACID, ... | Authors: | Zhang, Y, Looger, L.L. | Deposit date: | 2021-11-11 | Release date: | 2022-11-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Fast and sensitive GCaMP calcium indicators for imaging neural populations Nature, 615, 2023
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6O7G
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6L2G
| Crystal structure of Aspergillus fumigatus mitochondrial acetyl-CoA acetyltransferase | Descriptor: | Acetyl-CoA-acetyltransferase, putative | Authors: | Zhang, Y, Wei, W, Raimi, O.G, Ferenbach, A.T, Fang, W. | Deposit date: | 2019-10-03 | Release date: | 2020-02-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Aspergillus fumigatus Mitochondrial Acetyl Coenzyme A Acetyltransferase as an Antifungal Target. Appl.Environ.Microbiol., 86, 2020
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6L2C
| Crystal structure of Aspergillus fumigatus mitochondrial acetyl-CoA acetyltransferase in complex with CoA | Descriptor: | Acetyl-CoA-acetyltransferase, putative, COENZYME A | Authors: | Zhang, Y, Wei, W, Raimi, O.G, Ferenbach, A.T, Fang, W. | Deposit date: | 2019-10-03 | Release date: | 2020-02-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Aspergillus fumigatus Mitochondrial Acetyl Coenzyme A Acetyltransferase as an Antifungal Target. Appl.Environ.Microbiol., 86, 2020
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6LN5
| CryoEM structure of SERCA2b T1032stop in E1-2Ca2+-AMPPCP (class1) | Descriptor: | CALCIUM ION, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | Authors: | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | Deposit date: | 2019-12-28 | Release date: | 2020-08-26 | Last modified: | 2020-09-16 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail. Sci Adv, 6, 2020
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6LN9
| CryoEM structure of SERCA2b T1032stop in E2-BeF3- state (class2) | Descriptor: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | Authors: | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | Deposit date: | 2019-12-28 | Release date: | 2020-08-26 | Last modified: | 2020-09-16 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail. Sci Adv, 6, 2020
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6LN7
| CryoEM structure of SERCA2b T1032stop in E1-2Ca2+-AMPPCP (class3) | Descriptor: | CALCIUM ION, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | Authors: | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | Deposit date: | 2019-12-28 | Release date: | 2020-08-26 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail. Sci Adv, 6, 2020
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6LO8
| Cryo-EM structure of the TIM22 complex from yeast | Descriptor: | Mitochondrial import inner membrane translocase subunit TIM10, Mitochondrial import inner membrane translocase subunit TIM12, Mitochondrial import inner membrane translocase subunit TIM18, ... | Authors: | Zhang, Y, Zhou, X, Wu, X, Li, L. | Deposit date: | 2020-01-04 | Release date: | 2020-09-30 | Last modified: | 2021-03-17 | Method: | ELECTRON MICROSCOPY (3.83 Å) | Cite: | Structure of the mitochondrial TIM22 complex from yeast. Cell Res., 31, 2021
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6LN6
| CryoEM structure of SERCA2b T1032stop in E1-2Ca2+-AMPPCP (class2) | Descriptor: | CALCIUM ION, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | Authors: | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | Deposit date: | 2019-12-28 | Release date: | 2020-08-26 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail. Sci Adv, 6, 2020
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