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6XH2
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BU of 6xh2 by Molmil
Co-crystal structure of HIV-1 TAR RNA in complex with lab-evolved RRM 6.6
Descriptor: TAR-BINDING PROTEIN 6.6, TRANS-ACTIVATION RESPONSE ELEMENT
Authors:Chavali, S.S, Jenkins, J.L, Wedekind, J.E.
Deposit date:2020-06-18
Release date:2020-10-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors.
J.Biol.Chem., 295, 2020
4XNN
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BU of 4xnn by Molmil
Crystal Structure of a GH7 Family Cellobiohydrolase from Daphnia pulex
Descriptor: Cellobiohydrolase CHBI, GLYCEROL
Authors:Ebrahim, A, Hobdey, S.E, Podkaminer, K, Taylor II, L.E, Beckham, G.T, Decker, S.R, Himmel, M.E, Cragg, S.M, McGeehan, J.E.
Deposit date:2015-01-15
Release date:2016-01-27
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Characterization of a GH7 Family Cellobiohydrolase from Daphnia pulex
To Be Published
2NUF
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BU of 2nuf by Molmil
Crystal structure of RNase III from Aquifex aeolicus complexed with ds-RNA at 2.5-Angstrom Resolution
Descriptor: 28-MER, MAGNESIUM ION, Ribonuclease III
Authors:Gan, J.H, Shaw, G, Tropea, J.E, Waugh, D.S, Court, D.L, Ji, X.
Deposit date:2006-11-09
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A stepwise model for double-stranded RNA processing by ribonuclease III.
Mol.Microbiol., 67, 2007
3LOB
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BU of 3lob by Molmil
Crystal Structure of Flock House Virus calcium mutant
Descriptor: Coat protein beta, Coat protein gamma, RNA (5'-R(*UP*UP*U*AP*UP*CP*UP*(P))-3'), ...
Authors:Johnson, J.E, Banerjee, M, Speir, J.A, Huang, R.
Deposit date:2010-02-03
Release date:2010-04-21
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structure and function of a genetically engineered mimic of a nonenveloped virus entry intermediate.
J.Virol., 84, 2010
3LCP
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BU of 3lcp by Molmil
Crystal structure of the carbohydrate recognition domain of LMAN1 in complex with MCFD2
Descriptor: CALCIUM ION, Multiple coagulation factor deficiency protein 2, Protein ERGIC-53
Authors:Wigren, E, Bourhis, J.M, Kursula, I, Guy, J.E, Lindqvist, Y.
Deposit date:2010-01-11
Release date:2010-01-26
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structure of the LMAN1-CRD/MCFD2 transport receptor complex provides insight into combined deficiency of factor V and factor VIII.
Febs Lett., 584, 2010
2QJJ
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BU of 2qjj by Molmil
Crystal structure of D-Mannonate dehydratase from Novosphingobium aromaticivorans
Descriptor: MAGNESIUM ION, Mandelate racemase/muconate lactonizing enzyme
Authors:Fedorov, A.A, Fedorov, E.V, Rakus, J.F, Vick, J.E, Gerlt, J.A, Almo, S.C.
Deposit date:2007-07-07
Release date:2007-10-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Evolution of enzymatic activities in the enolase superfamily: D-Mannonate dehydratase from Novosphingobium aromaticivorans.
Biochemistry, 46, 2007
4Y2E
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BU of 4y2e by Molmil
Crystal structure of the catalytic domain of human dual-specificity phosphatase 7 (C232S)
Descriptor: Dual specificity protein phosphatase 7, PHOSPHATE ION
Authors:Lountos, G.T, Austin, B.P, Tropea, J.E, Waugh, D.S.
Deposit date:2015-02-09
Release date:2015-06-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structure of human dual-specificity phosphatase 7, a potential cancer drug target.
Acta Crystallogr.,Sect.F, 71, 2015
2QBX
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BU of 2qbx by Molmil
EphB2/SNEW Antagonistic Peptide Complex
Descriptor: Ephrin type-B receptor 2, SULFATE ION, antagonistic peptide
Authors:Chrencik, J.E, Brooun, A, Recht, M.I, Nicola, G, Pasquale, E.B, Kuhn, P, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D)
Deposit date:2007-06-18
Release date:2007-11-06
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Three-dimensional structure of the EphB2 receptor in complex with an antagonistic peptide reveals a novel mode of inhibition.
J.Biol.Chem., 282, 2007
4XYP
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BU of 4xyp by Molmil
Crystal structure of a piscine viral fusion protein
Descriptor: 3,7-BIS(DIMETHYLAMINO)PHENOTHIAZIN-5-IUM, CHLORIDE ION, Fusion protein
Authors:Cook, J.D, Lee, J.E.
Deposit date:2015-02-02
Release date:2015-06-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Electrostatic Architecture of the Infectious Salmon Anemia Virus (ISAV) Core Fusion Protein Illustrates a Carboxyl-Carboxylate pH Sensor.
J.Biol.Chem., 290, 2015
2OT5
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BU of 2ot5 by Molmil
Crystal structure of the HIV gp41 core with the enfuvirtide resistance mutation N43D
Descriptor: HIV-1 gp41 glycoprotein
Authors:Bai, X, Seedorff, J.E, Green, J, Dwyer, J.J.
Deposit date:2007-02-07
Release date:2008-06-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Impact of the enfuvirtide resistance mutation N43D and the associated baseline polymorphism E137K on peptide sensitivity and six-helix bundle structure.
Biochemistry, 47, 2008
2OUE
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BU of 2oue by Molmil
Crystal structure of a junctionless all-RNA hairpin ribozyme at 2.05 angstroms resolution
Descriptor: COBALT HEXAMMINE(III), Loop A ribozyme strand, Loop B S-turn strand, ...
Authors:Wedekind, J.E.
Deposit date:2007-02-10
Release date:2007-03-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Water in the Active Site of an All-RNA Hairpin Ribozyme and Effects of Gua8 Base Variants on the Geometry of Phosphoryl Transfer.
Biochemistry, 45, 2006
6XMJ
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BU of 6xmj by Molmil
Human 20S proteasome bound to an engineered 11S (PA26) activator
Descriptor: Proteasome activator protein PA26, Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, ...
Authors:de la Pena, A.H, Opoku-Nsiah, K.A, Williams, S.K, Chopra, N, Sali, A, Gestwicki, J.E, Lander, G.C.
Deposit date:2020-06-30
Release date:2020-07-22
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3 Å)
Cite:The Y Phi motif defines the structure-activity relationships of human 20S proteasome activators.
Nat Commun, 13, 2022
6XH1
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BU of 6xh1 by Molmil
Co-crystal structure of HIV-1 TAR RNA in complex with lab-evolved RRM TBP6.7 mutant
Descriptor: TAR binding protein mutant 6.7 Q48R/T50R, TRANS-ACTIVATION RESPONSE ELEMENT
Authors:Chavali, S.S, Jenkins, J.L, Wedekind, J.E.
Deposit date:2020-06-18
Release date:2020-10-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors.
J.Biol.Chem., 295, 2020
1YPT
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BU of 1ypt by Molmil
CRYSTAL STRUCTURE OF YERSINIA PROTEIN TYROSINE PHOSPHATASE AT 2.5 ANGSTROMS AND THE COMPLEX WITH TUNGSTATE
Descriptor: PROTEIN-TYROSINE PHOSPHATASE YERSINIA (CATALYTIC DOMAIN)
Authors:Stuckey, J.A, Schubert, H.L, Fauman, E.B, Zhang, Z.-Y, Dixon, J.E, Saper, M.A.
Deposit date:1994-09-16
Release date:1994-12-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of Yersinia protein tyrosine phosphatase at 2.5 A and the complex with tungstate.
Nature, 370, 1994
4YG8
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BU of 4yg8 by Molmil
CRYSTAL STRUCTURE OF THE CHS5-CHS6 EXOMER CARGO ADAPTOR COMPLEX
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Chitin biosynthesis protein CHS5, Chitin biosynthesis protein CHS6, ...
Authors:Paczkowski, J.E, Richardson, B.C, Strassner, A.M, Fromme, J.C.
Deposit date:2015-02-26
Release date:2015-03-11
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The exomer cargo adaptor structure reveals a novel GTPase-binding domain.
Embo J., 31, 2012
4YCA
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BU of 4yca by Molmil
Evidence of Kinetic Cooperativity in dimeric Ketopantoate Reductase from Staphylococcus aureus
Descriptor: 2-dehydropantoate 2-reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Sanchez, J.E, Gross, P.G, Goetze, R, Walsh Jr, R.M, Peeples, W.B, Wood, Z.A.
Deposit date:2015-02-19
Release date:2015-03-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Evidence of Kinetic Cooperativity in Dimeric Ketopantoate Reductase from Staphylococcus aureus.
Biochemistry, 54, 2015
3LX2
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BU of 3lx2 by Molmil
Crystal Structure analysis of PCNA from Thermococcus kodakaraensis tk0582
Descriptor: DNA polymerase sliding clamp 2, SULFATE ION
Authors:Ladner, J.E, Kelman, Z, Pan, M.
Deposit date:2010-02-24
Release date:2011-01-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of two active proliferating cell nuclear antigens (PCNAs) encoded by Thermococcus kodakaraensis.
Proc.Natl.Acad.Sci.USA, 108, 2011
6Y5S
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BU of 6y5s by Molmil
Crystal structure of savinase at cryogenic conditions
Descriptor: CALCIUM ION, SODIUM ION, Subtilisin Savinase
Authors:Wu, S, Moroz, O, Turkenburg, J, Nielsen, J.E, Wilson, K.S, Teilum, K.
Deposit date:2020-02-25
Release date:2020-06-17
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:Conformational heterogeneity of Savinase from NMR, HDX-MS and X-ray diffraction analysis.
Peerj, 8, 2020
1YVL
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BU of 1yvl by Molmil
Structure of Unphosphorylated STAT1
Descriptor: 5-residue peptide, GOLD ION, Signal transducer and activator of transcription 1-alpha/beta
Authors:Mao, X, Ren, Z, Parker, G.N, Sondermann, H, Pastorello, M.A, Wang, W, McMurray, J.S, Demeler, B, Darnell Jr, J.E, Chen, X.
Deposit date:2005-02-16
Release date:2005-03-22
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural bases of unphosphorylated STAT1 association and receptor binding.
Mol.Cell, 17, 2005
6Y6T
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BU of 6y6t by Molmil
Mouse Galactocerebrosidase complexed with galacto-noeurostegine GNS at pH 4.6
Descriptor: (1~{R},2~{S},3~{S},4~{R},5~{R})-4-(hydroxymethyl)-8-azabicyclo[3.2.1]octane-1,2,3-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Deane, J.E, McLoughlin, J.
Deposit date:2020-02-27
Release date:2021-01-13
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The Bicyclic Form of galacto -Noeurostegine Is a Potent Inhibitor of beta-Galactocerebrosidase.
Acs Med.Chem.Lett., 12, 2021
2QJN
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BU of 2qjn by Molmil
Crystal structure of D-mannonate dehydratase from Novosphingobium aromaticivorans complexed with Mg and 2-keto-3-deoxy-D-gluconate
Descriptor: 2-KETO-3-DEOXYGLUCONATE, MAGNESIUM ION, Mandelate racemase/muconate lactonizing enzyme
Authors:Fedorov, A.A, Fedorov, E.V, Rakus, J.F, Vick, J.E, Gerlt, J.A, Almo, S.C.
Deposit date:2007-07-08
Release date:2007-10-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Evolution of enzymatic activities in the enolase superfamily: D-Mannonate dehydratase from Novosphingobium aromaticivorans.
Biochemistry, 46, 2007
2BDO
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BU of 2bdo by Molmil
SOLUTION STRUCTURE OF HOLO-BIOTINYL DOMAIN FROM ACETYL COENZYME A CARBOXYLASE OF ESCHERICHIA COLI DETERMINED BY TRIPLE-RESONANCE NMR SPECTROSCOPY
Descriptor: BIOTIN, PROTEIN (ACETYL-COA CARBOXYLASE)
Authors:Roberts, E.L, Shu, N, Howard, M.J, Broadhurst, R.W, Chapman-Smith, A, Wallace, J.C, Morris, T, Cronan, J.E, Perham, R.N.
Deposit date:1999-03-03
Release date:1999-04-27
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:Solution structures of apo and holo biotinyl domains from acetyl coenzyme A carboxylase of Escherichia coli determined by triple-resonance nuclear magnetic resonance spectroscopy.
Biochemistry, 38, 1999
2BCZ
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BU of 2bcz by Molmil
Crystal Structure of a minimal, mutant all-RNA hairpin ribozyme (U39C, G8I, 2'deoxy A-1)
Descriptor: 5'-R(*CP*GP*GP*UP*GP*AP*IP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*CP*CP*(DA)P*GP*UP*CP*CP*AP*CP*CP*G)-3'), ...
Authors:Salter, J.D, Wedekind, J.E.
Deposit date:2005-10-19
Release date:2006-02-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Water in the Active Site of an All-RNA Hairpin Ribozyme and Effects of Gua8 Base Variants on the Geometry of Phosphoryl Transfer.
Biochemistry, 45, 2006
4WOH
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BU of 4woh by Molmil
Structure of of human dual-specificity phosphatase 22 (E24A/K28A/K30A/C88S) complexed with 4-nitrophenolphosphate
Descriptor: 1,2-ETHANEDIOL, 4-NITROPHENYL PHOSPHATE, DI(HYDROXYETHYL)ETHER, ...
Authors:Lountos, G.T, Cherry, S, Tropea, J.E, Waugh, D.S.
Deposit date:2014-10-15
Release date:2015-02-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Structural analysis of human dual-specificity phosphatase 22 complexed with a phosphotyrosine-like substrate.
Acta Crystallogr.,Sect.F, 71, 2015
2QBY
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BU of 2qby by Molmil
Crystal structure of a heterodimer of Cdc6/Orc1 initiators bound to origin DNA (from S. solfataricus)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 6 homolog 1, Cell division control protein 6 homolog 3, ...
Authors:Cunningham Dueber, E.L, Corn, J.E, Bell, S.D, Berger, J.M.
Deposit date:2007-06-18
Release date:2007-09-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Replication origin recognition and deformation by a heterodimeric archaeal Orc1 complex.
Science, 317, 2007

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