6LHP
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![BU of 6lhp by Molmil](/molmil-images/mine/6lhp) | The cryo-EM structure of coxsackievirus A16 mature virion in complex with Fab 14B10 | Descriptor: | SPHINGOSINE, VP1 protein, VP2 protein, ... | Authors: | He, M.Z, Xu, L.F, Zheng, Q.B, Zhu, R, Yin, Z.C, Cheng, T, Li, S.W. | Deposit date: | 2019-12-09 | Release date: | 2020-02-05 | Last modified: | 2020-02-26 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Identification of Antibodies with Non-overlapping Neutralization Sites that Target Coxsackievirus A16. Cell Host Microbe, 27, 2020
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6KVH
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![BU of 6kvh by Molmil](/molmil-images/mine/6kvh) | The mutant crystal structure of endo-polygalacturonase (T284A) from Talaromyces leycettanus JCM 12802 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose, endo-polygalacturonase | Authors: | Tu, T, Wang, Z, Luo, H, Yao, B. | Deposit date: | 2019-09-04 | Release date: | 2020-09-09 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structural Insights into the Mechanisms Underlying the Kinetic Stability of GH28 Endo-Polygalacturonase. J.Agric.Food Chem., 69, 2021
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6LHO
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![BU of 6lho by Molmil](/molmil-images/mine/6lho) | The cryo-EM structure of coxsackievirus A16 empty particle in complex with Fab 18A7 | Descriptor: | VP1 protein, VP2 protein, VP3 protein | Authors: | He, M.Z, Xu, L.F, Zheng, Q.B, Zhu, R, Yin, Z.C, Cheng, T, Li, S.W. | Deposit date: | 2019-12-09 | Release date: | 2020-02-05 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.13 Å) | Cite: | Identification of Antibodies with Non-overlapping Neutralization Sites that Target Coxsackievirus A16. Cell Host Microbe, 27, 2020
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6L31
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![BU of 6l31 by Molmil](/molmil-images/mine/6l31) | L1 protein of human papillomavirus 6 | Descriptor: | Major capsid protein L1 | Authors: | Li, S.W, Liu, X.L, Gu, Y. | Deposit date: | 2019-10-07 | Release date: | 2019-12-25 | Method: | ELECTRON MICROSCOPY (4.18 Å) | Cite: | Neutralization sites of human papillomavirus-6 relate to virus attachment and entry phase in viral infection. Emerg Microbes Infect, 8, 2019
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7YLM
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![BU of 7ylm by Molmil](/molmil-images/mine/7ylm) | Cryo-EM structure of 8-subunit Smc5/6 hinge region | Descriptor: | MMS21 isoform 1, SMC6 isoform 1, Structural maintenance of chromosomes protein 5 | Authors: | Qian, L, Jun, Z, Xiang, Z, Wang, Z, Tong, C, Duo, J, Zhenguo, C, Wang, L. | Deposit date: | 2022-07-26 | Release date: | 2024-01-31 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (6.17 Å) | Cite: | Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms. Nat.Struct.Mol.Biol., 2024
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6A85
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![BU of 6a85 by Molmil](/molmil-images/mine/6a85) | Crystal structure of a novel DNA quadruplex | Descriptor: | AMMONIUM ION, DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*TP*GP*GP*GP*TP*GP*CP*GP*TP*T)-3'), LEAD (II) ION, ... | Authors: | Liu, H.H, Gan, J.H. | Deposit date: | 2018-07-06 | Release date: | 2019-03-06 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | High-resolution DNA quadruplex structure containing all the A-, G-, C-, T-tetrads. Nucleic Acids Res., 46, 2018
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6LHK
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![BU of 6lhk by Molmil](/molmil-images/mine/6lhk) | The cryo-EM structure of coxsackievirus A16 mature virion in complex with Fab 18A7 | Descriptor: | SPHINGOSINE, VP1 protein, VP2 protein, ... | Authors: | He, M.Z, Xu, L.F, Zheng, Q.B, Zhu, R, Yin, Z.C, Cheng, T, Li, S.W. | Deposit date: | 2019-12-09 | Release date: | 2020-02-05 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.65 Å) | Cite: | Identification of Antibodies with Non-overlapping Neutralization Sites that Target Coxsackievirus A16. Cell Host Microbe, 27, 2020
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6LHA
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![BU of 6lha by Molmil](/molmil-images/mine/6lha) | The cryo-EM structure of coxsackievirus A16 mature virion | Descriptor: | SPHINGOSINE, VP1 protein, VP2 protein, ... | Authors: | He, M.Z, Xu, L.F, Zheng, Q.B, Zhu, R, Yin, Z.C, Cheng, T, Li, S.W. | Deposit date: | 2019-12-07 | Release date: | 2020-02-05 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.56 Å) | Cite: | Identification of Antibodies with Non-overlapping Neutralization Sites that Target Coxsackievirus A16. Cell Host Microbe, 27, 2020
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6LHQ
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![BU of 6lhq by Molmil](/molmil-images/mine/6lhq) | The cryo-EM structure of coxsackievirus A16 mature virion in complex with Fab NA9D7 | Descriptor: | SPHINGOSINE, VP1 protein, VP2 protein, ... | Authors: | He, M.Z, Xu, L.F, Zheng, Q.B, Zhu, R, Yin, Z.C, Cheng, T, Li, S.W. | Deposit date: | 2019-12-09 | Release date: | 2020-02-05 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | Identification of Antibodies with Non-overlapping Neutralization Sites that Target Coxsackievirus A16. Cell Host Microbe, 27, 2020
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6LHT
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![BU of 6lht by Molmil](/molmil-images/mine/6lht) | Localized reconstruction of coxsackievirus A16 mature virion in complex with Fab 18A7 | Descriptor: | SPHINGOSINE, VP1 protein, heavy chain variable region of Fab 18A7, ... | Authors: | He, M.Z, Xu, L.F, Zheng, Q.B, Zhu, R, Yin, Z.C, Cheng, T, Li, S.W. | Deposit date: | 2019-12-10 | Release date: | 2020-02-05 | Last modified: | 2020-02-26 | Method: | ELECTRON MICROSCOPY (3.67 Å) | Cite: | Identification of Antibodies with Non-overlapping Neutralization Sites that Target Coxsackievirus A16. Cell Host Microbe, 27, 2020
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7KTQ
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![BU of 7ktq by Molmil](/molmil-images/mine/7ktq) | Nucleosome from a dimeric PRC2 bound to a nucleosome | Descriptor: | 601 DNA (167-MER), Histone H2A, Histone H2B, ... | Authors: | Grau, D.J, Armache, K.J. | Deposit date: | 2020-11-24 | Release date: | 2021-02-03 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction. Nat Commun, 12, 2021
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7YQH
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![BU of 7yqh by Molmil](/molmil-images/mine/7yqh) | Cryo-EM structure of 8-subunit Smc5/6 | Descriptor: | DNA repair protein KRE29, E3 SUMO-protein ligase MMS21, Non-structural maintenance of chromosome element 3, ... | Authors: | Qian, L, Jun, Z, Xiang, Z, Tong, C, Zhaoning, W, Duo, J, Zhenguo, C, Lanfeng, W. | Deposit date: | 2022-08-07 | Release date: | 2024-01-31 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (5.6 Å) | Cite: | Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms. Nat.Struct.Mol.Biol., 2024
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6J1U
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![BU of 6j1u by Molmil](/molmil-images/mine/6j1u) | influenza virus nucleoprotein with a specific inhibitor | Descriptor: | Nucleoprotein, ~{N}-[4-[(4-~{tert}-butylphenyl)carbonylamino]phenyl]-2,3-dihydro-1,4-benzodioxine-6-carboxamide | Authors: | Pang, B, Zhang, W.Z, Zhang, H.M, Hao, Q. | Deposit date: | 2018-12-29 | Release date: | 2020-01-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Discovery of a Novel Specific Inhibitor Targeting Influenza A Virus Nucleoprotein with Pleiotropic Inhibitory Effects on Various Steps of the Viral Life Cycle. J.Virol., 95, 2021
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6AWM
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![BU of 6awm by Molmil](/molmil-images/mine/6awm) | PawL-Derived Peptide PLP-4 | Descriptor: | GLY-LEU-LEU-GLY-ILE-THR-ASP | Authors: | Fisher, M, Mylne, J.S, Howard, M.J. | Deposit date: | 2017-09-05 | Release date: | 2018-03-07 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | A family of small, cyclic peptides buried in preproalbumin since the Eocene epoch. Plant Direct, 2, 2018
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6AWK
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![BU of 6awk by Molmil](/molmil-images/mine/6awk) | |
6AZG
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![BU of 6azg by Molmil](/molmil-images/mine/6azg) | |
6AXI
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![BU of 6axi by Molmil](/molmil-images/mine/6axi) | PawL-Derived Peptide PLP-2 | Descriptor: | ASP-LEU-PHE-VAL-PRO-PRO-ILE-ASP | Authors: | Fisher, M, Mylne, J.S, Howard, M.J. | Deposit date: | 2017-09-06 | Release date: | 2018-03-07 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | A family of small, cyclic peptides buried in preproalbumin since the Eocene epoch. Plant Direct, 2, 2018
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6BHX
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![BU of 6bhx by Molmil](/molmil-images/mine/6bhx) | B. subtilis SsbA with DNA | Descriptor: | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Single-stranded DNA-binding protein A | Authors: | Dubiel, K.D, Myers, A.R, Satyshur, K.A, Keck, J.L. | Deposit date: | 2017-10-31 | Release date: | 2018-12-19 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.936 Å) | Cite: | Structural Mechanisms of Cooperative DNA Binding by Bacterial Single-Stranded DNA-Binding Proteins. J. Mol. Biol., 431, 2019
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7KW1
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![BU of 7kw1 by Molmil](/molmil-images/mine/7kw1) | Structure of hSTING in complex with novel carbocyclic pyrimidine CDN-3 | Descriptor: | (2R,5R,7R,8R,10R,12aR,14R,15aS,16R)-7-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-16-hydroxy-14-[(pyrimidin-4-yl)oxy]-2,10-disulfanyldecahydro-2H,10H-5,8-methano-2lambda~5~,10lambda~5~-cyclopenta[l][1,3,6,9,11,2,10]pentaoxadiphosphacyclotetradecine-2,10-dione, Stimulator of interferon genes protein | Authors: | Skene, R. | Deposit date: | 2020-11-29 | Release date: | 2021-06-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Identification of Novel Carbocyclic Pyrimidine Cyclic Dinucleotide STING Agonists for Antitumor Immunotherapy Using Systemic Intravenous Route. J.Med.Chem., 64, 2021
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7KVX
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![BU of 7kvx by Molmil](/molmil-images/mine/7kvx) | Structure of hSTING in complex with novel carbocyclic pyrimidine CDN 1 | Descriptor: | (2R,5R,7R,8R,10R,12aR,14R,15aS,16R)-7-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-16-hydroxy-14-[(pyrimidin-4-yl)amino]-2,10-disulfanyldecahydro-2H,10H-5,8-methano-2lambda~5~,10lambda~5~-cyclopenta[l][1,3,6,9,11,2,10]pentaoxadiphosphacyclotetradecine-2,10-dione, Stimulator of interferon genes protein | Authors: | Skene, R. | Deposit date: | 2020-11-29 | Release date: | 2021-06-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Identification of Novel Carbocyclic Pyrimidine Cyclic Dinucleotide STING Agonists for Antitumor Immunotherapy Using Systemic Intravenous Route. J.Med.Chem., 64, 2021
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6AXJ
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![BU of 6axj by Molmil](/molmil-images/mine/6axj) | |
6BHW
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![BU of 6bhw by Molmil](/molmil-images/mine/6bhw) | B. subtilis SsbA | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Single-stranded DNA-binding protein A | Authors: | Dubiel, K.D, Myers, A.R, Satyshur, K.A, Keck, J.L. | Deposit date: | 2017-10-31 | Release date: | 2018-12-19 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.208 Å) | Cite: | Structural Mechanisms of Cooperative DNA Binding by Bacterial Single-Stranded DNA-Binding Proteins. J. Mol. Biol., 431, 2019
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6JKM
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![BU of 6jkm by Molmil](/molmil-images/mine/6jkm) | Crystal structure of BubR1 kinase domain | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | Authors: | Lin, L, Ye, S, Huang, Y, Liu, X, Zhang, R, Yao, X. | Deposit date: | 2019-03-01 | Release date: | 2019-06-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules. Cell Res., 29, 2019
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6JKK
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![BU of 6jkk by Molmil](/molmil-images/mine/6jkk) | Crystal structure of BubR1 kinase domain | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Mitotic checkpoint control protein kinase BUB1 | Authors: | Lin, L, Ye, S, Huang, Y, Liu, X, Zhang, R, Yao, X. | Deposit date: | 2019-03-01 | Release date: | 2019-06-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules. Cell Res., 29, 2019
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6AZF
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![BU of 6azf by Molmil](/molmil-images/mine/6azf) | |