3J3I
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![BU of 3j3i by Molmil](/molmil-images/mine/3j3i) | Penicillium chrysogenum virus (PcV) capsid structure | Descriptor: | Capsid protein | Authors: | Luque, D, Gomez-Blanco, J, Garriga, D, Brilot, A, Gonzalez, J.M, Havens, W.H, Carrascosa, J.L, Trus, B.L, Verdaguer, N, Grigorieff, N, Ghabrial, S.A, Caston, J.R. | Deposit date: | 2013-03-08 | Release date: | 2014-05-14 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Cryo-EM near-atomic structure of a dsRNA fungal virus shows ancient structural motifs preserved in the dsRNA viral lineage. Proc.Natl.Acad.Sci.USA, 111, 2014
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5ME5
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![BU of 5me5 by Molmil](/molmil-images/mine/5me5) | Crystal Structure of eiF4E from C. melo bound to a eIF4G peptide | Descriptor: | Eukaryotic transcription initiation factor 4E, SULFATE ION, eIF4G | Authors: | Querol-Audi, J, Silva, C, Miras, M, Truniger, V, Aranda-Regules, M, Verdaguer, N. | Deposit date: | 2016-11-14 | Release date: | 2017-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of eIF4E in Complex with an eIF4G Peptide Supports a Universal Bipartite Binding Mode for Protein Translation. Plant Physiol., 174, 2017
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4L3B
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![BU of 4l3b by Molmil](/molmil-images/mine/4l3b) | X-ray structure of the HRV2 A particle uncoating intermediate | Descriptor: | Protein VP1, Protein VP2, Protein VP3 | Authors: | Vives-Adrian, L, Querol-Audi, J, Garriga, D, Pous, J, Verdaguer, N. | Deposit date: | 2013-06-05 | Release date: | 2013-11-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (6.5 Å) | Cite: | Uncoating of common cold virus is preceded by RNA switching as determined by X-ray and cryo-EM analyses of the subviral A-particle. Proc.Natl.Acad.Sci.USA, 110, 2013
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4IQX
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![BU of 4iqx by Molmil](/molmil-images/mine/4iqx) | Mutant P44S P169S M296I of Foot-and-mouth disease Virus RNA-dependent RNA polymerase | Descriptor: | 3D polymerase, RNA (5'-R(*AP*UP*GP*GP*GP*CP*C)-3'), RNA (5'-R(*GP*GP*CP*CP*C)-3') | Authors: | Ferrer-Orta, C, Verdaguer, N, Agudo, R, Perez-Luque, R. | Deposit date: | 2013-01-14 | Release date: | 2013-02-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape. Plos Pathog., 6, 2010
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3GNF
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![BU of 3gnf by Molmil](/molmil-images/mine/3gnf) | P1 Crystal structure of the N-terminal R1-R7 of murine MVP | Descriptor: | Major vault protein | Authors: | Querol-Audi, J, Casanas, A, Uson, I, Luque, D, Caston, J.R, Fita, I, Verdaguer, N. | Deposit date: | 2009-03-17 | Release date: | 2009-11-10 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The mechanism of vault opening from the high resolution structure of the N-terminal repeats of MVP Embo J., 28, 2009
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4NP9
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![BU of 4np9 by Molmil](/molmil-images/mine/4np9) | Structure of Rabphilin C2A domain bound to IP3 | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Rabphilin-3A, SULFATE ION | Authors: | Guillen, J, Ferrer-Orta, C, Buxaderas, M, Perez-Sanchez, D, Guerrero-Valero, M, Luengo-Gil, G, Pous, J, Guerra, P, Gomez-Fernandez, J.C, Verdaguer, N, Corbalan-Garcia, S. | Deposit date: | 2013-11-21 | Release date: | 2013-12-25 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1. Proc.Natl.Acad.Sci.USA, 110, 2013
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3NL0
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![BU of 3nl0 by Molmil](/molmil-images/mine/3nl0) | Mutant P44S M296I of Foot-and-mouth disease Virus RNA-dependent RNA polymerase | Descriptor: | 3D polymerase, 5'-R(*G*GP*GP*CP*CP*C)-3', 5'-R(P*UP*GP*GP*GP*CP*CP*C)-3', ... | Authors: | Agudo, R, Ferrer-Orta, C, Arias, A, Perez-Luque, R, Verdaguer, N, Domingo, E. | Deposit date: | 2010-06-21 | Release date: | 2011-07-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape. Plos Pathog., 6, 2010
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3NKY
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![BU of 3nky by Molmil](/molmil-images/mine/3nky) | Structure of a mutant P44S of Foot-and-mouth disease Virus RNA-dependent RNA polymerase | Descriptor: | 3D polymerase, MAGNESIUM ION | Authors: | Agudo, R, Ferrer-Orta, C, Arias, A, Perez-Luque, R, Verdaguer, N, Domingo, E. | Deposit date: | 2010-06-21 | Release date: | 2011-05-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape. Plos Pathog., 6, 2010
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3NMA
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![BU of 3nma by Molmil](/molmil-images/mine/3nma) | Mutant P169S of Foot-and-mouth disease Virus RNA dependent RNA-polymerase | Descriptor: | 5'-R(*GP*GP*C)-3', 5'-R(P*CP*C)-3', Genome polyprotein, ... | Authors: | Agudo, R, Ferrer-Orta, C, Arias, A, Perez-Luque, R, Verdaguer, N, Domingo, E. | Deposit date: | 2010-06-22 | Release date: | 2011-05-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape. Plos Pathog., 6, 2010
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4PDW
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![BU of 4pdw by Molmil](/molmil-images/mine/4pdw) | A benzonitrile analogue inhibits rhinovirus replication | Descriptor: | 4-[(4,5-dimethoxy-2-nitrophenyl)acetyl]benzonitrile, Capsid protein VP4/VP2, GLYCEROL, ... | Authors: | Querol-Audi, J, Guerra, P, Lacroix, C, Roche, M, Franco, D, Froeyen, M, Terme, T, Vanelle, P, Neyts, J, Leyssen, P, Verdaguer, N. | Deposit date: | 2014-04-22 | Release date: | 2014-07-02 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A novel benzonitrile analogue inhibits rhinovirus replication. J.Antimicrob.Chemother., 69, 2014
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4NYZ
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![BU of 4nyz by Molmil](/molmil-images/mine/4nyz) | The EMCV 3Dpol structure with altered motif A conformation at 2.15A resolution | Descriptor: | GLUTAMINE, GLYCEROL, Genome polyprotein, ... | Authors: | Vives-adrian, L, Lujan, C, Ferrer-orta, C, Verdaguer, N. | Deposit date: | 2013-12-11 | Release date: | 2014-03-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | The crystal structure of a cardiovirus RNA-dependent RNA polymerase reveals an unusual conformation of the polymerase active site J.Virol., 88, 2014
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4NZ0
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![BU of 4nz0 by Molmil](/molmil-images/mine/4nz0) | |
2D7S
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![BU of 2d7s by Molmil](/molmil-images/mine/2d7s) | Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with VPg protein | Descriptor: | RNA-dependent RNA polymerase, VPg1 protein | Authors: | Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. | Deposit date: | 2005-11-29 | Release date: | 2006-03-28 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The structure of a protein primer-polymerase complex in the initiation of genome replication Embo J., 25, 2006
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2F8E
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![BU of 2f8e by Molmil](/molmil-images/mine/2f8e) | Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with uridylylated VPg protein | Descriptor: | MAGNESIUM ION, MANGANESE (II) ION, RNA-dependent RNA polymerase, ... | Authors: | Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. | Deposit date: | 2005-12-02 | Release date: | 2006-03-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The structure of a protein primer-polymerase complex in the initiation of genome replication Embo J., 25, 2006
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3GPE
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![BU of 3gpe by Molmil](/molmil-images/mine/3gpe) | Crystal Structure Analysis of PKC (alpha)-C2 domain complexed with Ca2+ and PtdIns(4,5)P2 | Descriptor: | CALCIUM ION, PHOSPHATE ION, Protein kinase C alpha type, ... | Authors: | Ferrer-Orta, C, Querol-Audi, J, Fita, I, Verdaguer, N. | Deposit date: | 2009-03-23 | Release date: | 2009-05-05 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and mechanistic insights into the association of PKCalpha-C2 domain to PtdIns(4,5)P2. Proc.Natl.Acad.Sci.USA, 106, 2009
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3GNG
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![BU of 3gng by Molmil](/molmil-images/mine/3gng) | P21B crystal structure of R1-R7 of Murine MVP | Descriptor: | Major vault protein | Authors: | Querol-Audi, J, Casanas, A, Uson, I, Caston, J.R, Fita, I, Verdaguer, N. | Deposit date: | 2009-03-17 | Release date: | 2009-11-10 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The mechanism of vault opening from the high resolution structure of the N-terminal repeats of MVP Embo J., 28, 2009
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368D
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![BU of 368d by Molmil](/molmil-images/mine/368d) | STRUCTURAL VARIABILITY OF A-DNA IN CRYSTALS OF THE OCTAMER D(PCPCPCPGPCPGPGPG) | Descriptor: | DNA (5'-D(P*CP*CP*CP*GP*CP*GP*GP*G)-3') | Authors: | Fernandez, L.G, Subirana, J.A, Verdaguer, N, Pyshnyi, D, Campos, L, Malinina, L. | Deposit date: | 1997-12-19 | Release date: | 1998-07-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural variability of A-DNA in crystals of the octamer d(pCpCpCpGpCpGpGpG) J.Biomol.Struct.Dyn., 15, 1997
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371D
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![BU of 371d by Molmil](/molmil-images/mine/371d) | STRUCTURAL VARIABILITY OF A-DNA IN CRYSTALS OF THE OCTAMER D(PCPCPCPGPCPGPGPG) | Descriptor: | DNA (5'-D(P*CP*CP*CP*GP*CP*GP*GP*G)-3') | Authors: | Fernandez, L.G, Subirana, J.A, Verdaguer, N, Pyshnyi, D, Campos, L. | Deposit date: | 1997-12-19 | Release date: | 1998-07-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural variability of A-DNA in crystals of the octamer d(pCpCpCpGpCpGpGpG) J.Biomol.Struct.Dyn., 15, 1997
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370D
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![BU of 370d by Molmil](/molmil-images/mine/370d) | STRUCTURAL VARIABILITY OF A-DNA IN CRYSTALS OF THE OCTAMER D(PCPCPCPGPCPGPGPG) | Descriptor: | DNA (5'-D(P*CP*CP*CP*GP*CP*GP*GP*G)-3'), MAGNESIUM ION | Authors: | Fernandez, L.G, Subirana, J.A, Verdaguer, N, Pyshnyi, D, Campos, L. | Deposit date: | 1997-12-19 | Release date: | 1998-07-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Structural variability of A-DNA in crystals of the octamer d(pCpCpCpGpCpGpGpG) J.Biomol.Struct.Dyn., 15, 1997
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369D
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![BU of 369d by Molmil](/molmil-images/mine/369d) | STRUCTURAL VARIABILITY OF A-DNA IN CRYSTALS OF THE OCTAMER D(PCPCPCPGPCPGPGPG) | Descriptor: | DNA (5'-D(P*CP*CP*CP*GP*CP*GP*GP*G)-3') | Authors: | Fernandez, L.G, Subirana, J.A, Verdaguer, N, Pyshnyi, D, Campos, L. | Deposit date: | 1997-12-19 | Release date: | 1998-07-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural variability of A-DNA in crystals of the octamer d(pCpCpCpGpCpGpGpG) J.Biomol.Struct.Dyn., 15, 1997
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372D
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![BU of 372d by Molmil](/molmil-images/mine/372d) | STRUCTURAL VARIABILITY OF A-DNA IN CRYSTALS OF THE OCTAMER D(PCPCPCPGPCPGPGPG) | Descriptor: | DNA (5'-D(P*CP*CP*CP*GP*CP*GP*GP*G)-3') | Authors: | Fernandez, L.G, Subirana, J.A, Verdaguer, N, Pyshnyi, D, Campos, L. | Deposit date: | 1997-12-19 | Release date: | 1998-07-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural variability of A-DNA in crystals of the octamer d(pCpCpCpGpCpGpGpG) J.Biomol.Struct.Dyn., 15, 1997
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2Z7J
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![BU of 2z7j by Molmil](/molmil-images/mine/2z7j) | Structural insights into de multifunctional VP3 protein of birnaviruses:gold derivative | Descriptor: | Capsid assembly protein VP3, GOLD ION | Authors: | Casanas, A, Navarro, A, Ferrer-Orta, C, Gonzalez, D, Rodriguez, J.F, Verdaguer, N. | Deposit date: | 2007-08-23 | Release date: | 2008-02-05 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural insights into the multifunctional protein VP3 of birnaviruses. Structure, 16, 2008
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2E9Z
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![BU of 2e9z by Molmil](/molmil-images/mine/2e9z) | Foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA, ATP and UTP | Descriptor: | 5'-R(*CP*AP*UP*GP*GP*GP*CP*CP*C)-3', 5'-R(*GP*GP*GP*CP*CP*CP*A)-3', MAGNESIUM ION, ... | Authors: | Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. | Deposit date: | 2007-01-29 | Release date: | 2007-06-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Sequential structures provide insights into the fidelity of RNA replication Proc.Natl.Acad.Sci.Usa, 104, 2007
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4Y34
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![BU of 4y34 by Molmil](/molmil-images/mine/4y34) | Crystal Structure of Coxsackievirus B3 3D polymerase in complex with GPC-N143 | Descriptor: | 2,2'-[(4-fluorobenzene-1,2-diyl)bis(oxy)]bis(5-nitrobenzonitrile), 3D polymerase, GLYCEROL, ... | Authors: | Vives-Adrian, L, Ferrer-Orta, C, Cerdaguer, N. | Deposit date: | 2015-02-10 | Release date: | 2015-04-01 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family. Plos Pathog., 11, 2015
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8C2P
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![BU of 8c2p by Molmil](/molmil-images/mine/8c2p) | FMDV 3D polymerase in complex with 3B3 | Descriptor: | Protein 3B-3, RNA-directed RNA polymerase 3D-POL | Authors: | Ferrer-Orta, C, Veraguer, N. | Deposit date: | 2022-12-22 | Release date: | 2023-04-26 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Dual role of the foot-and-mouth disease virus 3B1 protein in the replication complex: As protein primer and as an essential component to recruit 3Dpol to membranes. Plos Pathog., 19, 2023
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