2H77
 
 | | Crystal structure of human TR alpha bound T3 in monoclinic space group | | Descriptor: | 3,5,3'TRIIODOTHYRONINE, THRA protein | | Authors: | Nascimento, A.S, Dias, S.M.G, Nunes, F.M, Aparicio, R, Bleicher, L, Ambrosio, A.L.B, Figueira, A.C.M, Santos, M.A.M, Neto, M.O, Fischer, H, Togashi, H.F.M, Craievich, A.F, Garrat, R.C, Baxter, J.D, Webb, P, Polikarpov, I. | | Deposit date: | 2006-06-01 | | Release date: | 2006-07-25 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.33 Å) | | Cite: | Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function.
J.Mol.Biol., 360, 2006
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2H79
 | | Crystal Structure of human TR alpha bound T3 in orthorhombic space group | | Descriptor: | 3,5,3'TRIIODOTHYRONINE, THRA protein | | Authors: | Nascimento, A.S, Dias, S.M.G, Nunes, F.M, Aparicio, R, Bleicher, L, Ambrosio, A.L.B, Figueira, A.C.M, Santos, M.A.M, Neto, M.O, Fischer, H, Togashi, H.F.M, Craievich, A.F, Garrat, R.C, Baxter, J.D, Webb, P, Polikarpov, I. | | Deposit date: | 2006-06-01 | | Release date: | 2006-07-25 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function.
J.Mol.Biol., 360, 2006
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3CFQ
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6XOF
 | | Crystal structure of SCLam, a non-specific endo-beta-1,3(4)-glucanase from family GH16 | | Descriptor: | CALCIUM ION, GH16 family protein, GLYCEROL | | Authors: | Liberato, M.V, Bernardes, A, Polikarpov, I, Squina, F. | | Deposit date: | 2020-07-07 | | Release date: | 2021-02-10 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Insights into the dual cleavage activity of the GH16 laminarinase enzyme class on beta-1,3 and beta-1,4 glycosidic bonds.
J.Biol.Chem., 296, 2021
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1GMZ
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1GQN
 | | Native 3-dehydroquinase from Salmonella typhi | | Descriptor: | 3-DEHYDROQUINATE DEHYDRATASE | | Authors: | Lee, W.-H, Perles, L.A, Nagem, R.A.P, Polikarpov, I, Sawyer, L. | | Deposit date: | 2001-11-26 | | Release date: | 2003-11-20 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Comparison of Different Crystal Forms of 3-Dehydroquinase from Salmonella Typhi and its Implications for Enzyme Activity
Acta Crystallogr.,Sect.D, 58, 2002
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1HWU
 | | STRUCTURE OF PII PROTEIN FROM HERBASPIRILLUM SEROPEDICAE | | Descriptor: | PII PROTEIN | | Authors: | Benelli, E.M, Buck, M, Polikarpov, I, De Souza, E.M, Cruz, L.M, Pedrosa, F.O. | | Deposit date: | 2001-01-10 | | Release date: | 2003-06-17 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Herbaspirillum seropedicae signal transduction protein PII is structurally similar to the enteric GlnK.
Eur.J.Biochem., 269, 2002
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2RC5
 | | Refined structure of FNR from Leptospira interrogans | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Ferredoxin-NADP reductase, SULFATE ION, ... | | Authors: | Nascimento, A.S, Catalano-Dupuy, D.L, Polikarpov, I, Ceccarelli, E.A. | | Deposit date: | 2007-09-19 | | Release date: | 2008-03-25 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.431 Å) | | Cite: | Crystal structures of Leptospira interrogans FAD-containing ferredoxin-NADP+ reductase and its complex with NADP+.
Bmc Struct.Biol., 7, 2007
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1QFE
 | | THE STRUCTURE OF TYPE I 3-DEHYDROQUINATE DEHYDRATASE FROM SALMONELLA TYPHI | | Descriptor: | 3-AMINO-4,5-DIHYDROXY-CYCLOHEX-1-ENECARBOXYLATE, PROTEIN (3-DEHYDROQUINATE DEHYDRATASE) | | Authors: | Shrive, A.K, Polikarpov, I, Sawyer, L, Coggins, J.R, Hawkins, A.R. | | Deposit date: | 1999-04-05 | | Release date: | 2000-04-05 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The two types of 3-dehydroquinase have distinct structures but catalyze the same overall reaction.
Nat.Struct.Biol., 6, 1999
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1QG5
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1QLL
 | | Piratoxin-II (Prtx-II) - a K49 PLA2 from Bothrops pirajai | | Descriptor: | N-TRIDECANOIC ACID, PHOSPHOLIPASE A2 | | Authors: | Lee, W.-H, Polikarpov, I. | | Deposit date: | 1999-09-01 | | Release date: | 2000-09-07 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Structural Basis for Low Catalytic Activity in Lys49 Phospholipases A2-A Hypothesis: The Crystal Structure of Piratoxin II Complexed to Fatty Acid
Biochemistry, 40, 2001
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3NEX
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1L9W
 | | CRYSTAL STRUCTURE OF 3-DEHYDROQUINASE FROM SALMONELLA TYPHI COMPLEXED WITH REACTION PRODUCT | | Descriptor: | 3-AMINO-4,5-DIHYDROXY-CYCLOHEX-1-ENECARBOXYLATE, 3-dehydroquinate dehydratase aroD | | Authors: | Lee, W.H, Perles, L.A, Nagem, R.A.P, Shrive, A.K, Hawkins, A, Sawyer, L, Polikarpov, I. | | Deposit date: | 2002-03-26 | | Release date: | 2003-03-26 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Comparison of different crystal forms of 3-dehydroquinase from Salmonella typhi and its implication for the enzyme activity.
Acta Crystallogr.,Sect.D, 58, 2002
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3NES
 | | V30M mutant human transthyretin (TTR) complexed with GC-1 (V30M:GC-1) | | Descriptor: | GLYCEROL, Transthyretin, {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid | | Authors: | Trivella, D.B.B, Polikarpov, I. | | Deposit date: | 2010-06-09 | | Release date: | 2010-11-24 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | The binding of synthetic triiodo l-thyronine analogs to human transthyretin: molecular basis of cooperative and non-cooperative ligand recognition.
J.Struct.Biol., 173, 2011
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3NEO
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1B8E
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1DN0
 | | STRUCTURE OF THE FAB FRAGMENT FROM A HUMAN IGM COLD AGGLUTININ | | Descriptor: | IGM-KAPPA COLD AGGLUTININ (HEAVY CHAIN), IGM-KAPPA COLD AGGLUTININ (LIGHT CHAIN) | | Authors: | Cauerhff, A, Braden, B, Carvalho, J.G, Leoni, J, Polikarpov, I, Goldbaum, F. | | Deposit date: | 1999-12-15 | | Release date: | 2001-01-24 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Three-dimensional structure of the Fab from a human IgM cold agglutinin.
J.Immunol., 165, 2000
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3ILN
 | | X-ray structure of the laminarinase from Rhodothermus marinus | | Descriptor: | CALCIUM ION, GLYCEROL, Laminarinase | | Authors: | Bleicher, L, Golubev, A, Rojas, A.L, Nascimento, A.S, Polikarpov, I. | | Deposit date: | 2009-08-07 | | Release date: | 2010-08-18 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Molecular basis of the thermostability and thermophilicity of laminarinases: X-ray structure of the hyperthermostable laminarinase from Rhodothermus marinus and molecular dynamics simulations.
J.Phys.Chem.B, 115, 2011
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3KGU
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3KGT
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3HZF
 | | Structure of TR-alfa bound to selective thyromimetic GC-1 in C2 space group | | Descriptor: | Thyroid hormone receptor, alpha isoform 1 variant, {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid | | Authors: | Aparicio, R, Bleicher, L, Polikarpov, I. | | Deposit date: | 2009-06-23 | | Release date: | 2009-07-21 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms.
Bmc Struct.Biol., 8, 2008
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3I36
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3KGS
 | | V30M mutant human transthyretin (TTR) (apoV30M) pH 7.5 | | Descriptor: | Transthyretin | | Authors: | Trivella, D.B, Polikarpov, I. | | Deposit date: | 2009-10-29 | | Release date: | 2010-03-23 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding.
J.Struct.Biol., 170, 2010
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3G9V
 | | Crystal structure of a soluble decoy receptor IL-22BP bound to interleukin-22 | | Descriptor: | Interleukin 22 receptor, alpha 2, Interleukin-22 | | Authors: | de Moura, P.R, Watanabe, L, Bleicher, L, Colau, D, Renauld, J.-C, Polikarpov, I. | | Deposit date: | 2009-02-14 | | Release date: | 2009-04-14 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.756 Å) | | Cite: | Crystal structure of a soluble decoy receptor IL-22BP bound to interleukin-22
FEBS Lett., 583, 2009
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3DLQ
 | | Crystal structure of the IL-22/IL-22R1 complex | | Descriptor: | Interleukin-22, Interleukin-22 receptor subunit alpha-1 | | Authors: | Bleicher, L, de Moura, P.R, Watanabe, L, Colau, D, Dumoutier, L, Renauld, J.-C, Polikarpov, I. | | Deposit date: | 2008-06-28 | | Release date: | 2008-08-19 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of the IL-22/IL-22R1 complex and its implications for the IL-22 signaling mechanism
Febs Lett., 582, 2008
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