5XNB
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7T4E
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7T4D
| Pore structure of pore-forming toxin Epx4 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Epx4 | Authors: | Xiong, X.Z, Dong, M, Yang, P, Abraham, J. | Deposit date: | 2021-12-09 | Release date: | 2022-03-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Emerging enterococcus pore-forming toxins with MHC/HLA-I as receptors. Cell, 185, 2022
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5GUD
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6KKS
| Structural insights into target DNA recognition by R2R3-type MYB transcription factor | Descriptor: | DNA (5'-D(*AP*AP*AP*TP*TP*CP*TP*CP*CP*AP*AP*CP*CP*GP*CP*AP*TP*TP*TP*TP*C)-3'), DNA (5'-D(*CP*GP*AP*AP*AP*AP*TP*GP*CP*GP*GP*TP*TP*GP*GP*AP*GP*AP*AP*TP*T)-3'), MAGNESIUM ION, ... | Authors: | Wang, B, Luo, Q. | Deposit date: | 2019-07-27 | Release date: | 2019-11-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural insights into target DNA recognition by R2R3-MYB transcription factors. Nucleic Acids Res., 48, 2020
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6M2M
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8VJV
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8VJW
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8VJX
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8VJU
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8VJY
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7YC9
| Co-crystal structure of BTK kinase domain with inhibitor | Descriptor: | (7~{S})-2-(4-bromanyl-3,5-dimethoxy-phenyl)-7-(1-propanoylpiperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide, 1,2-ETHANEDIOL, Tyrosine-protein kinase BTK | Authors: | Zhou, X. | Deposit date: | 2022-07-01 | Release date: | 2023-05-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Discovery of BGB-8035, a Highly Selective Covalent Inhibitor of Bruton's Tyrosine Kinase for B-Cell Malignancies and Autoimmune Diseases. J.Med.Chem., 66, 2023
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7Y0Z
| Crystal structure of Pseudomonas aeruginosa PvrA | Descriptor: | TetR family transcriptional regulator | Authors: | Liang, H, Zhang, Q, Bartlam, M. | Deposit date: | 2022-06-06 | Release date: | 2023-02-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Regulatory and structural mechanisms of PvrA-mediated regulation of the PQS quorum-sensing system and PHA biosynthesis in Pseudomonas aeruginosa. Nucleic Acids Res., 51, 2023
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7Y0Y
| Crystal structure of Pseudomonas aeruginosa PvrA (SeMet) | Descriptor: | TetR family transcriptional regulator | Authors: | Liang, H, Zhang, Q, Bartlam, M. | Deposit date: | 2022-06-06 | Release date: | 2023-02-08 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Regulatory and structural mechanisms of PvrA-mediated regulation of the PQS quorum-sensing system and PHA biosynthesis in Pseudomonas aeruginosa. Nucleic Acids Res., 51, 2023
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7WVD
| Crystal structure of H14 complexed with SIA28 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SIA28, ... | Authors: | Chen, Y, Qi, J, Gao, G.F. | Deposit date: | 2022-02-10 | Release date: | 2023-01-18 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (3.39 Å) | Cite: | Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes. Nat Commun, 13, 2022
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7WVI
| Crystal structure of SIA28 | Descriptor: | Heavy chain of SIA28, Light chain of SIA28 | Authors: | Chen, Y, Qi, J, Gao, G.F. | Deposit date: | 2022-02-10 | Release date: | 2023-01-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes. Nat Commun, 13, 2022
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7WVG
| Crystal structure of H18 complexed with SIA28 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SIA28, ... | Authors: | Chen, Y, Qi, J, Gao, G.F. | Deposit date: | 2022-02-10 | Release date: | 2023-01-18 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes. Nat Commun, 13, 2022
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7P99
| Structure of human USPL1 in complex with SUMO2 | Descriptor: | SUMO-specific isopeptidase USPL1, Small ubiquitin-related modifier, ZINC ION | Authors: | Reverter, D, Ying, L. | Deposit date: | 2021-07-26 | Release date: | 2022-03-02 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for the SUMO protease activity of the atypical ubiquitin-specific protease USPL1. Nat Commun, 13, 2022
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4FMX
| Crystal Structure of Substrate-Bound P450cin | Descriptor: | 1,3,3-TRIMETHYL-2-OXABICYCLO[2.2.2]OCTANE, GLYCEROL, P450cin, ... | Authors: | Madrona, Y, Tripathi, S.M, Huiying, L, Poulos, T.L. | Deposit date: | 2012-06-18 | Release date: | 2012-07-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.554 Å) | Cite: | Crystal structures of substrate-free and nitrosyl cytochrome p450cin: implications for o(2) activation. Biochemistry, 51, 2012
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