8VJV

Structure of Human Neurolysin in complex with dynorphin A8(1-8) peptide

Summary for 8VJV

• Entry DOI: 10.2210/pdb8vjv/pdb
• Descriptor: Neurolysin, mitochondrial, Dynorphin A(1-8), ZINC ION, ... (6 entities in total)
• Functional Keywords: metallopeptidase, bioactive peptides, hydrolase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 77882.77

Authors

Shi, K.,Aihara, H. (deposition date: 2024-01-08, release date: 2024-08-21)

• Primary citation: Shi, K.,Bagchi, S.,Bickel, J.,Esfahani, S.H.,Yin, L.,Cheng, T.,Karamyan, V.T.,Aihara, H.; Structural basis of divergent substrate recognition and inhibition of human neurolysin.; Sci Rep, 14:18420-18420, 2024; PubMed: 39117724; DOI: 10.1038/s41598-024-67639-w

Experimental method

X-RAY DIFFRACTION (2.12 Å)