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6FWD
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BU of 6fwd by Molmil
Crystal structure of human transthyretin double mutant R34G/T119M at pH 5.5
Descriptor: Transthyretin
Authors:Esperante, S, Ventura, S, Reverter, D, Varejao, N.
Deposit date:2018-03-06
Release date:2019-03-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.576 Å)
Cite:Disease-associated mutations impacting BC-loop flexibility trigger long-range transthyretin tetramer destabilization and aggregation.
J.Biol.Chem., 297, 2021
6GUM
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BU of 6gum by Molmil
Structure of the A.thaliana E1 UFD domain in complex with E2
Descriptor: GLYCEROL, SAE2, SUMO-conjugating enzyme SCE1
Authors:Liu, B, Lois, L.M, Reverter, D.
Deposit date:2018-06-19
Release date:2019-07-03
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.792 Å)
Cite:Structural insights into SUMO E1-E2 interactions in Arabidopsis uncovers a distinctive platform for securing SUMO conjugation specificity across evolution.
Biochem.J., 476, 2019
6GV3
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BU of 6gv3 by Molmil
Structure of the E2 conjugating enzyme, SCE1, from Arabidopsis thaliana.
Descriptor: SUMO-conjugating enzyme SCE1
Authors:Liu, B, Lois, L.M, Reverter, D.
Deposit date:2018-06-20
Release date:2019-07-03
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.201 Å)
Cite:Structural insights into SUMO E1-E2 interactions in Arabidopsis uncovers a distinctive platform for securing SUMO conjugation specificity across evolution.
Biochem.J., 476, 2019
1KFX
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BU of 1kfx by Molmil
Crystal Structure of Human m-Calpain Form I
Descriptor: M-CALPAIN LARGE SUBUNIT, M-CALPAIN SMALL SUBUNIT
Authors:Strobl, S, Fernandez-Catalan, C, Braun, M, Huber, R, Masumoto, H, Nakagawa, K, Irie, A, Sorimachi, H, Bourenkow, G, Bartunik, H, Suzuki, K, Bode, W.
Deposit date:2001-11-23
Release date:2001-12-07
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium.
Proc.Natl.Acad.Sci.USA, 97, 2000
1KFU
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BU of 1kfu by Molmil
Crystal Structure of Human m-Calpain Form II
Descriptor: M-CALPAIN LARGE SUBUNIT, M-CALPAIN SMALL SUBUNIT
Authors:Strobl, S, Fernandez-Catalan, C, Braun, M, Huber, R, Masumoto, H, Nakagawa, K, Irie, A, Sorimachi, H, Bourenkow, G, Bartunik, H, Suzuki, K, Bode, W.
Deposit date:2001-11-23
Release date:2001-12-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium.
Proc.Natl.Acad.Sci.USA, 97, 2000
5DE2
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BU of 5de2 by Molmil
Structural mechanism of Nek7 activation by Nek9-induced dimerisation
Descriptor: Serine/threonine-protein kinase Nek7, Serine/threonine-protein kinase Nek9
Authors:Haq, T, Bayliss, R.
Deposit date:2015-08-25
Release date:2015-11-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Mechanistic basis of Nek7 activation through Nek9 binding and induced dimerization.
Nat Commun, 6, 2015
2ABZ
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BU of 2abz by Molmil
Crystal structure of C19A/C43A mutant of leech carboxypeptidase inhibitor in complex with bovine carboxypeptidase A
Descriptor: Carboxypeptidase A1, Metallocarboxypeptidase inhibitor, ZINC ION
Authors:Arolas, J.L, Popowicz, G.M, Bronsoms, S, Aviles, F.X, Huber, R, Holak, T.A, Ventura, S.
Deposit date:2005-07-18
Release date:2006-01-31
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Study of a major intermediate in the oxidative folding of leech carboxypeptidase inhibitor: contribution of the fourth disulfide bond
J.Mol.Biol., 352, 2005
1ZFI
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BU of 1zfi by Molmil
Solution structure of the leech carboxypeptidase inhibitor
Descriptor: Metallocarboxypeptidase inhibitor
Authors:Arolas, J.L, D'Silva, L, Popowicz, G.M, Aviles, F.X, Holak, T.A, Ventura, S.
Deposit date:2005-04-20
Release date:2005-09-13
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:NMR structural characterization and computational predictions of the major intermediate in oxidative folding of leech carboxypeptidase inhibitor
STRUCTURE, 13, 2005
1ZFL
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BU of 1zfl by Molmil
Solution structure of III-A, the major intermediate in the oxidative folding of leech carboxypeptidase inhibitor
Descriptor: Metallocarboxypeptidase inhibitor
Authors:Arolas, J.L, D'Silva, L, Popowicz, G.M, Aviles, F.X, Holak, T.A, Ventura, S.
Deposit date:2005-04-20
Release date:2005-09-13
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:NMR structural characterization and computational predictions of the major intermediate in oxidative folding of leech carboxypeptidase inhibitor
STRUCTURE, 13, 2005
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