5Y59
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![BU of 5y59 by Molmil](/molmil-images/mine/5y59) | Crystal structure of Ku80 and Sir4 | Descriptor: | ATP-dependent DNA helicase II subunit 2, SULFATE ION, Sir4p | Authors: | Chen, H, Xue, J, Wu, J, Lei, M. | Deposit date: | 2017-08-08 | Release date: | 2017-12-20 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.402 Å) | Cite: | Structural Insights into Yeast Telomerase Recruitment to Telomeres Cell, 172, 2018
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5Y5A
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![BU of 5y5a by Molmil](/molmil-images/mine/5y5a) | Crystal structure of Est1 and Cdc13 | Descriptor: | KLLA0F20702p, KLLA0F20922p | Authors: | Chen, H, Xue, J, Wu, J, Lei, M. | Deposit date: | 2017-08-08 | Release date: | 2017-12-20 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.206 Å) | Cite: | Structural Insights into Yeast Telomerase Recruitment to Telomeres Cell, 172, 2018
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6MLC
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![BU of 6mlc by Molmil](/molmil-images/mine/6mlc) | PHD6 domain of MLL3 in complex with histone H4 | Descriptor: | GLYCEROL, Histone H4, Histone-lysine N-methyltransferase 2C, ... | Authors: | Dong, A, Liu, Y, Qin, S, Lei, M, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2018-09-27 | Release date: | 2018-10-24 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4. Nat Commun, 10, 2019
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5WQD
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![BU of 5wqd by Molmil](/molmil-images/mine/5wqd) | |
5Y58
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![BU of 5y58 by Molmil](/molmil-images/mine/5y58) | Crystal structure of Ku70/80 and TLC1 | Descriptor: | ATP-dependent DNA helicase II subunit 1, ATP-dependent DNA helicase II subunit 2, TLC1 | Authors: | Chen, H, Xue, J, Wu, J, Lei, M. | Deposit date: | 2017-08-08 | Release date: | 2017-12-20 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Insights into Yeast Telomerase Recruitment to Telomeres Cell, 172, 2018
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5XUP
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![BU of 5xup by Molmil](/molmil-images/mine/5xup) | Crystal structure of TRF1 and TERB1 | Descriptor: | Telomere repeats-binding bouquet formation protein 1, Telomeric repeat-binding factor 1 | Authors: | Long, J, Huang, C, Wu, J, Lei, M. | Deposit date: | 2017-06-24 | Release date: | 2017-11-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Telomeric TERB1-TRF1 interaction is crucial for male meiosis. Nat. Struct. Mol. Biol., 24, 2017
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8HMD
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![BU of 8hmd by Molmil](/molmil-images/mine/8hmd) | base module state 2 of Tetrahymena IFT-A | Descriptor: | Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 43 homolog, Tetratricopeptide repeat protein, ... | Authors: | Ma, Y, Wu, J, Lei, M. | Deposit date: | 2022-12-03 | Release date: | 2023-06-14 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train. Nat Commun, 14, 2023
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8HME
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![BU of 8hme by Molmil](/molmil-images/mine/8hme) | head module state 1 of Tetrahymena IFT-A | Descriptor: | Intraflagellar transport protein 122 homolog, Intraflagellar transporter, WD40 repeat protein, ... | Authors: | Ma, Y, Wu, J, Lei, M. | Deposit date: | 2022-12-03 | Release date: | 2023-06-14 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train. Nat Commun, 14, 2023
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8HMC
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![BU of 8hmc by Molmil](/molmil-images/mine/8hmc) | base module state 1 of Tetrahymena IFT-A | Descriptor: | Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 43 homolog, Tetratricopeptide repeat protein, ... | Authors: | Ma, Y, Wu, J, Lei, M. | Deposit date: | 2022-12-03 | Release date: | 2023-06-14 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train. Nat Commun, 14, 2023
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3RSN
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![BU of 3rsn by Molmil](/molmil-images/mine/3rsn) | Crystal Structure of the N-terminal region of Human Ash2L | Descriptor: | Set1/Ash2 histone methyltransferase complex subunit ASH2, ZINC ION | Authors: | Chen, Y, Wan, B, Wang, K.C, Cao, F, Yang, Y, Protacio, A, Dou, Y, Chang, H.Y, Lei, M. | Deposit date: | 2011-05-02 | Release date: | 2011-06-22 | Last modified: | 2011-12-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding. Embo Rep., 12, 2011
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8HPP
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![BU of 8hpp by Molmil](/molmil-images/mine/8hpp) | Crystal structure of human INTS3 with SAGE1 | Descriptor: | Integrator complex subunit 3, Sarcoma antigen 1 | Authors: | Deng, W, Wu, J, Lei, M. | Deposit date: | 2022-12-12 | Release date: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Cancer-testis antigen SAGE1 is a pan-cancer master regulator of RNA polymerase II To Be Published
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8HMF
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![BU of 8hmf by Molmil](/molmil-images/mine/8hmf) | head module state 2 of Tetrahymena IFT-A | Descriptor: | Intraflagellar transport protein 122 homolog, Intraflagellar transporter, WD40 repeat protein, ... | Authors: | Ma, Y, Wu, J, Lei, M. | Deposit date: | 2022-12-03 | Release date: | 2023-06-14 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train. Nat Commun, 14, 2023
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3RMH
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![BU of 3rmh by Molmil](/molmil-images/mine/3rmh) | Crystal Structure of yeast telomere protein Cdc13 OB4 | Descriptor: | Yeast Cdc13 OB4 | Authors: | Sun, J, Yang, Y, Lei, M. | Deposit date: | 2011-04-20 | Release date: | 2011-11-09 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.902 Å) | Cite: | Analyses of Candida Cdc13 Orthologues Revealed a Novel OB Fold Dimer Arrangement, Dimerization-Assisted DNA Binding, and Substantial Structural Differences between Cdc13 and RPA70. Mol.Cell.Biol., 32, 2012
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3U85
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![BU of 3u85 by Molmil](/molmil-images/mine/3u85) | |
3U86
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![BU of 3u86 by Molmil](/molmil-images/mine/3u86) | |
3U4V
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![BU of 3u4v by Molmil](/molmil-images/mine/3u4v) | |
3U4Z
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![BU of 3u4z by Molmil](/molmil-images/mine/3u4z) | |
3U88
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![BU of 3u88 by Molmil](/molmil-images/mine/3u88) | Crystal structure of human menin in complex with MLL1 and LEDGF | Descriptor: | (4beta,8alpha,9R)-6'-methoxy-10,11-dihydrocinchonan-9-ol, CHOLIC ACID, GLYOXYLIC ACID, ... | Authors: | Huang, J, Wan, B, Lei, M. | Deposit date: | 2011-10-16 | Release date: | 2012-02-15 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The same pocket in menin binds both MLL and JUND but has opposite effects on transcription. Nature, 482, 2012
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3TOJ
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![BU of 3toj by Molmil](/molmil-images/mine/3toj) | Structure of the SPRY domain of human Ash2L | Descriptor: | Set1/Ash2 histone methyltransferase complex subunit ASH2 | Authors: | Chen, Y, Cao, F, Wan, B, Dou, Y, Lei, M. | Deposit date: | 2011-09-05 | Release date: | 2012-01-25 | Last modified: | 2017-08-23 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Structure of the SPRY domain of human Ash2L and its interactions with RbBP5 and DPY30. Cell Res., 22, 2012
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3U50
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![BU of 3u50 by Molmil](/molmil-images/mine/3u50) | Crystal Structure of the Tetrahymena telomerase processivity factor Teb1 OB-C | Descriptor: | Telomerase-associated protein 82, ZINC ION | Authors: | Zeng, Z, Huang, J, Yang, Y, Lei, M. | Deposit date: | 2011-10-10 | Release date: | 2011-12-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for Tetrahymena telomerase processivity factor Teb1 binding to single-stranded telomeric-repeat DNA. Proc.Natl.Acad.Sci.USA, 108, 2011
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3U84
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![BU of 3u84 by Molmil](/molmil-images/mine/3u84) | Crystal Structure of Human Menin | Descriptor: | Menin | Authors: | Huang, J, Wan, B, Lei, M. | Deposit date: | 2011-10-15 | Release date: | 2012-02-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The same pocket in menin binds both MLL and JUND but has opposite effects on transcription. Nature, 482, 2012
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3U58
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![BU of 3u58 by Molmil](/molmil-images/mine/3u58) | Crystal Structure of the Tetrahymena telomerase processivity factor Teb1 AB | Descriptor: | DNA (5'-D(*GP*GP*GP*T)-3'), Tetrahymena Teb1 AB | Authors: | Zeng, Z, Huang, J, Yang, Y, Lei, M. | Deposit date: | 2011-10-11 | Release date: | 2011-12-28 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.613 Å) | Cite: | Structural basis for Tetrahymena telomerase processivity factor Teb1 binding to single-stranded telomeric-repeat DNA. Proc.Natl.Acad.Sci.USA, 108, 2011
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7WTD
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![BU of 7wtd by Molmil](/molmil-images/mine/7wtd) | Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the intermediate state 1 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, COENZYME A, Pyruvate carboxylase, ... | Authors: | Chai, P, Lan, P, Wu, J, Lei, M. | Deposit date: | 2022-02-04 | Release date: | 2022-11-09 | Last modified: | 2022-11-16 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
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7WTE
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![BU of 7wte by Molmil](/molmil-images/mine/7wte) | Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the intermediate state 2 | Descriptor: | ACETYL COENZYME *A, ADENOSINE-5'-TRIPHOSPHATE, Pyruvate carboxylase, ... | Authors: | Chai, P, Lan, P, Wu, J, Lei, M. | Deposit date: | 2022-02-04 | Release date: | 2022-11-09 | Last modified: | 2022-11-16 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
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7WTA
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![BU of 7wta by Molmil](/molmil-images/mine/7wta) | Cryo-EM structure of human pyruvate carboxylase in apo state | Descriptor: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Pyruvate carboxylase, mitochondrial | Authors: | Chai, P, Lan, P, Wu, J, Lei, M. | Deposit date: | 2022-02-04 | Release date: | 2022-11-09 | Last modified: | 2022-11-16 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA. Mol.Cell, 82, 2022
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