7VOB
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5YK0
| The complex structure of Rv3197-ADP from Mycobacterium tuberculosis | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, Probable conserved ATP-binding protein ABC transporter, ... | Authors: | Rao, Z.H, Zhang, Q.Q. | Deposit date: | 2017-10-11 | Release date: | 2018-02-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.102 Å) | Cite: | Discovery of the first macrolide antibiotic binding protein in Mycobacterium tuberculosis: a new antibiotic resistance drug target. Protein Cell, 9, 2018
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5YK2
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5ZF2
| Crystal structure of Trxlp from Edwardsiella tarda EIB202 | Descriptor: | SULFATE ION, Thioredoxin (H-type,TRX-H) | Authors: | Yang, C, Quan, S. | Deposit date: | 2018-03-02 | Release date: | 2019-03-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | The Edwardsiella piscicida thioredoxin-like protein inhibits ASK1-MAPKs signaling cascades to promote pathogenesis during infection. Plos Pathog., 15, 2019
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2MU3
| Spider wrapping silk fibre architecture arising from its modular soluble protein precursor | Descriptor: | Aciniform spidroin 1 | Authors: | Xu, L, Tremblay, M, Meng, Q, Liu, X, Rainey, J.K, Lefevre, T, Sarker, M, Orrell, K.E, Leclerc, J, Pezolet, M, Auger, M. | Deposit date: | 2014-09-03 | Release date: | 2015-07-08 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Spider wrapping silk fibre architecture arising from its modular soluble protein precursor. Sci Rep, 5, 2015
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8KHQ
| Bifunctional sulfoxide synthase OvoA_Th2 in complex with histidine and cysteine | Descriptor: | 5-histidylcysteine sulfoxide synthase/putative 4-mercaptohistidine N1-methyltranferase, COBALT (II) ION, CYSTEINE, ... | Authors: | Wang, J, Ye, K, Wang, X.Y, Yan, W.P. | Deposit date: | 2023-08-22 | Release date: | 2023-12-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Biochemical and Structural Characterization of OvoA Th2 : A Mononuclear Nonheme Iron Enzyme from Hydrogenimonas thermophila for Ovothiol Biosynthesis. Acs Catalysis, 13, 2023
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8E22
| VPS37A_21-148 | Descriptor: | Vacuolar protein sorting-associated protein 37A | Authors: | Tian, F, Ye, Y.S. | Deposit date: | 2022-08-12 | Release date: | 2023-08-09 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Identification of membrane curvature sensing motifs essential for VPS37A phagophore recruitment and autophagosome closure. Commun Biol, 7, 2024
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4RB4
| Crystal structure of dodecameric iron-containing heptosyltransferase TibC in complex with ADP-D-beta-D-heptose at 3.9 angstrom resolution | Descriptor: | 1,2-ETHANEDIOL, FE (III) ION, Glycosyltransferase tibC, ... | Authors: | Yao, Q, Lu, Q, Shao, F. | Deposit date: | 2014-09-12 | Release date: | 2014-11-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.88 Å) | Cite: | A structural mechanism for bacterial autotransporter glycosylation by a dodecameric heptosyltransferase family Elife, 3, 2014
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8HBK
| The crystal structure of SARS-CoV-2 3CL protease in complex with Ensitrelvir | Descriptor: | 3C-like proteinase nsp5, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione | Authors: | Lin, M. | Deposit date: | 2022-10-29 | Release date: | 2023-10-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Molecular mechanisms of SARS-CoV-2 resistance to nirmatrelvir. Nature, 622, 2023
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8J69
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5GPO
| The sensor domain structure of the zinc-responsive histidine kinase CzcS from Pseudomonas Aeruginosa | Descriptor: | SULFATE ION, Sensor protein CzcS, ZINC ION | Authors: | Wang, D, Chen, W.Z, Huang, S.Q, Liu, X.C, Hu, Q.Y, Wei, T.B, Gan, J.H, Chen, H. | Deposit date: | 2016-08-03 | Release date: | 2017-08-09 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.701 Å) | Cite: | Structural basis of Zn(II) induced metal detoxification and antibiotic resistance by histidine kinase CzcS in Pseudomonas aeruginosa PLoS Pathog., 13, 2017
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5SYB
| Crystal structure of human PHF5A | Descriptor: | 1,2-ETHANEDIOL, PHD finger-like domain-containing protein 5A, ZINC ION | Authors: | Tsai, J.H.C, Teng, T, Zhu, P, Fekkes, P, Larsen, N.A. | Deposit date: | 2016-08-10 | Release date: | 2016-09-07 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A-SF3b complex. Nat Commun, 8, 2017
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7S1M
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7S3I
| Ex4-D-Ala bound to the glucagon-like peptide-1 receptor/g protein complex (conformer 2) | Descriptor: | Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Belousoff, M.J, Piper, S.J, Danev, R. | Deposit date: | 2021-09-07 | Release date: | 2022-01-05 | Last modified: | 2022-03-16 | Method: | ELECTRON MICROSCOPY (2.51 Å) | Cite: | Structural and functional diversity among agonist-bound states of the GLP-1 receptor. Nat.Chem.Biol., 18, 2022
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5H9T
| Crystal structure of native NalD at resolution of 2.9, the secondary repressor of MexAB-OprM multidrug efflux pump in Pseudomonas aeruginosa | Descriptor: | NalD | Authors: | Chen, W.Z, Wang, D, Huang, S.Q, Hu, Q.Y, Liu, X.C, Gan, J.H, Chen, H. | Deposit date: | 2015-12-29 | Release date: | 2016-04-20 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Novobiocin binding to NalD induces the expression of the MexAB-OprM pump in Pseudomonas aeruginosa. Mol. Microbiol., 100, 2016
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5HAD
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5IQU
| WelO5 G166D variant bound to Fe(II), 2-oxoglutarate, and 12-epifischerindole U | Descriptor: | (6aS,9R,10R,10aS)-9-ethyl-10-isocyano-6,6,9-trimethyl-5,6,6a,7,8,9,10,10a-octahydroindeno[2,1-b]indole, 2-OXOGLUTARIC ACID, FE (II) ION, ... | Authors: | Mitchell, A.J, Maggiolo, A.O, Boal, A.K. | Deposit date: | 2016-03-11 | Release date: | 2016-06-29 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structural basis for halogenation by iron- and 2-oxo-glutarate-dependent enzyme WelO5. Nat.Chem.Biol., 12, 2016
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5WQA
| Crystal structure of PDE4D catalytic domain complexed with Selaginpulvilins K | Descriptor: | 1-[2-(4-hydroxyphenyl)ethynyl]-9,9-bis(4-methoxyphenyl)-7-oxidanyl-fluorene-2-carbaldehyde, MAGNESIUM ION, ZINC ION, ... | Authors: | Huang, Y, Zhang, T, Zheng, X, Yin, S, Luo, H.B. | Deposit date: | 2016-11-24 | Release date: | 2017-02-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The discovery, complex crystal structure, and recognition mechanism of a novel natural PDE4 inhibitor from Selaginella pulvinata Biochem. Pharmacol., 130, 2017
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3J0G
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5IYU
| AlgE_CIM | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Alginate production protein AlgE, ... | Authors: | Ma, P, Weichert, D. | Deposit date: | 2016-03-24 | Release date: | 2017-04-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The cubicon method for concentrating membrane proteins in the cubic mesophase. Nat Protoc, 12, 2017
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5KG8
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3WX8
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5KCL
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5KCY
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5KD0
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