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4ZEQ
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BU of 4zeq by Molmil
Crystal Structure of human BFL-1 in complex with tBid BH3 peptide, Northeast Structural Genomics Consortium Target HX9247
Descriptor: BH3-interacting domain death agonist, Bcl-2-related protein A1
Authors:Guan, R, Xiao, R, Mao, L, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2015-04-20
Release date:2015-05-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of human BFL-1 in complex with tBid BH3 peptide
To Be Published
3OWQ
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BU of 3owq by Molmil
X-Ray Structure of Lin1025 protein from Listeria innocua, Northeast Structural Genomics Consortium Target LkR164
Descriptor: DI(HYDROXYETHYL)ETHER, Lin1025 protein
Authors:Kuzin, A, Su, M, Lew, S, Seetharaman, J, Patel, P, Xiao, R, Ciccosanti, C, Lee, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2010-09-20
Release date:2010-10-20
Last modified:2012-02-22
Method:X-RAY DIFFRACTION (2.606 Å)
Cite:Northeast Structural Genomics Consortium Target LkR164
To be published
5GXH
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BU of 5gxh by Molmil
The structure of the Gemin5 WD40 domain with AAUUUUUG
Descriptor: GLYCEROL, Gem-associated protein 5, RNA (5'-R(*A*AP*UP*UP*UP*UP*UP*G)-3'), ...
Authors:Xu, C, He, H, Li, Y, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2016-09-17
Release date:2016-10-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly
Genes Dev., 30, 2016
3P9V
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BU of 3p9v by Molmil
High Resolution Crystal Structure of protein Maqu_3174 from Marinobacter aquaeolei, Northeast Structural Genomics Consortium Target MqR197
Descriptor: Uncharacterized protein
Authors:Kuzin, A, Chen, Y, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Wang, H, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2010-10-18
Release date:2010-10-27
Last modified:2012-02-22
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Northeast Structural Genomics Consortium Target MqR197
To be published
3P04
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BU of 3p04 by Molmil
Crystal Structure of the BCR protein from Corynebacterium glutamicum. Northeast Structural Genomics Consortium Target CgR8
Descriptor: Uncharacterized BCR
Authors:Vorobiev, S, Lew, S, Seetharaman, J, Hamilton, H, Xiao, R, Patel, D.J, Ciccosanti, C, Lee, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2010-09-27
Release date:2010-10-13
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of the BCR protein from Corynebacterium glutamicum. Northeast Structural Genomics Consortium Target CgR8.
To be Published
3OKZ
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BU of 3okz by Molmil
Crystal Structure of protein gbs0355 from Streptococcus agalactiae, Northeast Structural Genomics Consortium Target SaR127
Descriptor: Putative uncharacterized protein gbs0355
Authors:Kuzin, A, Lew, S, Vorobiev, S.M, Seetharaman, J, Janjua, J, Xiao, R, Ciccosanti, C, Wang, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2010-08-25
Release date:2010-09-22
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Northeast Structural Genomics Consortium Target SaR127
To be Published
3MEP
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BU of 3mep by Molmil
Crystal Structure of ECA2234 protein from Erwinia carotovora, Northeast Structural Genomics Consortium Target EwR44
Descriptor: uncharacterized protein ECA2234
Authors:Seetharaman, J, Abashidze, M, Forouhar, F, Mao, M, Xiao, R, Ciccosanti, C, Wang, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2010-03-31
Release date:2010-04-14
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Northeast Structural Genomics Consortium Target EwR44
To be Published
3P51
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BU of 3p51 by Molmil
Three-dimensional structure of protein Q2Y8N9_NITMU from nitrosospira multiformis, Northeast structural genomics consortium target NMR118
Descriptor: Uncharacterized protein
Authors:Kuzin, A, Chen, Y, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Lee, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2010-10-07
Release date:2010-10-27
Last modified:2012-02-22
Method:X-RAY DIFFRACTION (2.056 Å)
Cite:Northeast Structural Genomics Consortium Target NmR118
To be published
3PE5
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BU of 3pe5 by Molmil
Three-dimensional Structure of protein A7VV38_9CLOT from Clostridium leptum DSM 753, Northeast Structural Genomics Consortium Target QlR103
Descriptor: Uncharacterized protein
Authors:Kuzin, A, Su, M, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Wang, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2010-10-25
Release date:2010-11-10
Last modified:2012-02-22
Method:X-RAY DIFFRACTION (2.381 Å)
Cite:Northeast Structural Genomics Consortium Target QlR103
To be published
5DF6
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BU of 5df6 by Molmil
Crystal structure of PTPN11 tandem SH2 domains in complex with a TXNIP peptide
Descriptor: Tyrosine-protein phosphatase non-receptor type 11, UNKNOWN ATOM OR ION, txnip
Authors:Dong, A, Li, W, Tempel, W, Liu, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2015-08-26
Release date:2015-09-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structural basis for the regulatory role of the PPxY motifs in the thioredoxin-interacting protein TXNIP.
Biochem.J., 473, 2016
3PG5
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BU of 3pg5 by Molmil
Crystal structure of protein DIP2308 from Corynebacterium diphtheriae, Northeast Structural Genomics Consortium Target CdR78
Descriptor: Uncharacterized protein
Authors:Forouhar, F, Lew, S, Seetharaman, J, Lee, D, Ciccosanti, C, Sahdev, S, Nair, R, Rost, B, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2010-10-30
Release date:2010-12-22
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal structure of protein DIP2308 from Corynebacterium diphtheriae, Northeast Structural Genomics Consortium Target CdR78
To be Published
5DLB
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BU of 5dlb by Molmil
Crystal structure of chaperone EspG3 of ESX-3 type VII secretion system from Mycobacterium marinum M
Descriptor: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, GLYCEROL, PLATINUM (II) ION, ...
Authors:Chan, S, Arbing, M.A, Kim, J, Kahng, S, Sawaya, M.R, Eisenberg, D.S, TB Structural Genomics Consortium (TBSGC)
Deposit date:2015-09-04
Release date:2015-09-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structural Variability of EspG Chaperones from Mycobacterial ESX-1, ESX-3, and ESX-5 Type VII Secretion Systems.
J. Mol. Biol., 431, 2019
5E1M
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BU of 5e1m by Molmil
Crystal structure of NTMT1 in complex with PPKRIA peptide
Descriptor: GLYCEROL, N-terminal Xaa-Pro-Lys N-methyltransferase 1, RCC1, ...
Authors:Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2015-09-29
Release date:2015-10-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis for substrate recognition by the human N-terminal methyltransferase 1.
Genes Dev., 29, 2015
5E2A
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BU of 5e2a by Molmil
Crystal structure of NTMT1 in complex with N-terminally methylated SPKRIA peptide
Descriptor: GLYCEROL, N-terminal Xaa-Pro-Lys N-methyltransferase 1, RCC1, ...
Authors:Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2015-09-30
Release date:2015-10-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis for substrate recognition by the human N-terminal methyltransferase 1.
Genes Dev., 29, 2015
5E1B
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BU of 5e1b by Molmil
Crystal structure of NRMT1 in complex with SPKRIA peptide
Descriptor: GLYCEROL, N-terminal Xaa-Pro-Lys N-methyltransferase 1, RCC1, ...
Authors:Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2015-09-29
Release date:2015-10-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural basis for substrate recognition by the human N-terminal methyltransferase 1.
Genes Dev., 29, 2015
3MGD
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BU of 3mgd by Molmil
Crystal Structure of predicted acetyltransferase with acetyl-CoA from Clostridium acetobutylicum at the resolution 1.9A, Northeast Structural Genomics Consortium Target CaR165
Descriptor: ACETYL COENZYME *A, Predicted acetyltransferase
Authors:Kuzin, A, Chen, Y, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Zhao, L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2010-04-05
Release date:2010-04-28
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Northeast Structural Genomics Consortium Target CaR165
To be published
7FEO
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BU of 7feo by Molmil
Crystal structure of AtMBD5 MBD domain
Descriptor: Methyl-CpG-binding domain-containing protein 5, SULFATE ION
Authors:Zhou, M.Q, Wu, Z.B, Liu, K, Min, J.R, Structural Genomics Consortium (SGC)
Deposit date:2021-07-21
Release date:2021-12-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Family-wide Characterization of Methylated DNA Binding Ability of Arabidopsis MBDs.
J.Mol.Biol., 434, 2022
3NZL
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BU of 3nzl by Molmil
Crystal Structure of the N-terminal domain of DNA-binding protein SATB1 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4435B
Descriptor: DNA-binding protein SATB1
Authors:Forouhar, F, Abashidze, M, Seetharaman, J, Kuzin, A.P, Patel, P, Xiao, R, Ciccosanti, C, Shastry, R, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2010-07-16
Release date:2010-09-22
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.199 Å)
Cite:Crystal Structure of the N-terminal domain of DNA-binding protein SATB1 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4435B (CASP Target)
To be Published
6OGJ
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BU of 6ogj by Molmil
MeCP2 MBD in complex with DNA
Descriptor: DNA (5'-D(*CP*GP*GP*AP*GP*TP*GP*TP*AP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*TP*AP*CP*AP*CP*TP*CP*CP*G)-3'), Methyl-CpG-binding protein 2, ...
Authors:Lei, M, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2019-04-02
Release date:2019-05-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Plasticity at the DNA recognition site of the MeCP2 mCG-binding domain.
Biochim Biophys Acta Gene Regul Mech, 1862, 2019
6UNC
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BU of 6unc by Molmil
The crystal structure of Phosphopantetheinyl Hydrolase (PptH) from Mycobacterium tuberculosis
Descriptor: FE (III) ION, MANGANESE (II) ION, Metallophos domain-containing protein
Authors:Mosior, J.W, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2019-10-11
Release date:2020-04-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insights into phosphopantetheinyl hydrolase PptH from Mycobacterium tuberculosis.
Protein Sci., 29, 2020
3NRW
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BU of 3nrw by Molmil
Crystal Structure of the N-terminal domain of Phage integrase/site-specific recombinase (tnp) from Haloarcula marismortui, Northeast Structural Genomics Consortium Target HmR208A
Descriptor: Phage integrase/site-specific recombinase
Authors:Forouhar, F, Su, M, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Wang, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2010-06-30
Release date:2010-08-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Northeast Structural Genomics Consortium Target HmR208A
To be Published
5SYQ
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BU of 5syq by Molmil
Solution structure of Aquifex aeolicus Aq1974
Descriptor: Uncharacterized protein aq_1974
Authors:Sachleben, J.R, Gawlak, G, Hoey, R.J, Liu, G, Joachimiak, A, Montelione, G.T, Koide, S, Northeast Structural Genomics Consortium (NESG), Midwest Center for Structural Genomics (MCSG)
Deposit date:2016-08-11
Release date:2016-09-28
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Aromatic claw: A new fold with high aromatic content that evades structural prediction.
Protein Sci., 26, 2017
4EVW
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BU of 4evw by Molmil
Crystal Structure of the nucleoside-diphosphate-sugar pyrophosphorylase from Vibrio cholerae RC9. Northeast Structural Genomics Consortium (NESG) Target VcR193.
Descriptor: MAGNESIUM ION, Nucleoside-diphosphate-sugar pyrophosphorylase
Authors:Vorobiev, S, Neely, H, Su, M, Seetharaman, J, Mao, M, Xiao, R, Kohan, E, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-04-26
Release date:2012-05-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of the nucleoside-diphosphate-sugar pyrophosphorylase from Vibrio cholerae RC9.
To be Published
3B4T
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BU of 3b4t by Molmil
Crystal structure of Mycobacterium tuberculosis RNase PH, the Mycobacterium tuberculosis Structural Genomics Consortium target Rv1340
Descriptor: PHOSPHATE ION, Ribonuclease PH
Authors:Antczak, A.J, Berger, J.M, Lekin, T, Segelke, B.W, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB), TB Structural Genomics Consortium (TBSGC)
Deposit date:2007-10-24
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:2.1 A Crystal structure of RNase PH from Mycobacterium tuberculosis.
To be Published
4ESS
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BU of 4ess by Molmil
Crystal Structure of E6D/L155R variant of de novo designed serine hydrolase OSH55, Northeast Structural Genomics Consortium (NESG) Target OR187
Descriptor: OR187
Authors:Kuzin, A, Su, M, Seetharaman, J, Kornhaber, K, Kornhaber, G, Rajagopalan, S, Baker, D, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-04-23
Release date:2012-06-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9971 Å)
Cite:Design of activated serine-containing catalytic triads with atomic-level accuracy.
Nat.Chem.Biol., 10, 2014

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