3TB3
 
 | | Crystal structure of the UCH domain of UCH-L5 with 6 residues deleted | | Descriptor: | CALCIUM ION, Ubiquitin carboxyl-terminal hydrolase isozyme L5 | | Authors: | Zhou, Z.R, Zha, M, Zhou, J, Hu, H.Y. | | Deposit date: | 2011-08-05 | | Release date: | 2012-02-22 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Length of the active-site crossover loop defines the substrate specificity of ubiquitin C-terminal hydrolases for ubiquitin chains.
Biochem.J., 441, 2012
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8I1V
 | | The asymmetric unit of P22 procapsid | | Descriptor: | Major capsid protein, Scaffolding protein | | Authors: | Xiao, H, Liu, H.R, Cheng, L.P. | | Deposit date: | 2023-01-13 | | Release date: | 2023-03-08 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Assembly and Capsid Expansion Mechanism of Bacteriophage P22 Revealed by High-Resolution Cryo-EM Structures.
Viruses, 15, 2023
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8I1T
 | | The asymmetric unit of P22 empty capsid | | Descriptor: | Major capsid protein | | Authors: | Xiao, H, Liu, H.R, Cheng, L.P. | | Deposit date: | 2023-01-13 | | Release date: | 2023-03-08 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Assembly and Capsid Expansion Mechanism of Bacteriophage P22 Revealed by High-Resolution Cryo-EM Structures.
Viruses, 15, 2023
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8I99
 | | N-carbamoyl-D-amino-acid hydrolase mutant - M4Th3 | | Descriptor: | N-carbamoyl-D-amino-acid hydrolase | | Authors: | Hu, J.M, Ni, Y, Xu, G.C. | | Deposit date: | 2023-02-06 | | Release date: | 2023-03-22 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (3.17 Å) | | Cite: | Engineering the Thermostability of a d-Carbamoylase Based on Ancestral Sequence Reconstruction for the Efficient Synthesis of d-Tryptophan.
J.Agric.Food Chem., 71, 2023
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3NMW
 | | Crystal structure of armadillo repeats domain of APC | | Descriptor: | APC variant protein, SULFATE ION | | Authors: | Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G. | | Deposit date: | 2010-06-22 | | Release date: | 2011-07-06 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural basis for the recognition of Asef by adenomatous polyposis coli.
Cell Res., 22, 2012
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8HWT
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8HWS
 | | The complex structure of Omicron BA.4 RBD with BD604, S309, and S304 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, BD-604 Fab Heavy chain, BD-604 Fab Light chain, ... | | Authors: | He, Q.W, Xu, Z.P, Xie, Y.F. | | Deposit date: | 2023-01-02 | | Release date: | 2023-12-06 | | Method: | ELECTRON MICROSCOPY (2.36 Å) | | Cite: | An updated atlas of antibody evasion by SARS-CoV-2 Omicron sub-variants including BQ.1.1 and XBB.
Cell Rep Med, 4, 2023
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7YJ3
 | | Cryo-EM structure of SARS-CoV-2 Omicron BA.2 RBD in complex with human ACE2 (local refinement) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1, ... | | Authors: | Zhao, Z.N, Xie, Y.F, Qi, J.X, Gao, G.F. | | Deposit date: | 2022-07-19 | | Release date: | 2023-07-19 | | Last modified: | 2023-08-02 | | Method: | ELECTRON MICROSCOPY (3.14 Å) | | Cite: | Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants.
Nat Commun, 14, 2023
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7YHW
 | | Cryo-EM structure of SARS-CoV-2 Omicron BA.2.12.1 RBD in complex with human ACE2 (local refinement) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Zhao, Z.N, Xie, Y.F, Qi, J.X, Gao, G.F. | | Deposit date: | 2022-07-14 | | Release date: | 2023-07-19 | | Last modified: | 2023-08-02 | | Method: | ELECTRON MICROSCOPY (3.09 Å) | | Cite: | Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants.
Nat Commun, 14, 2023
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3NMZ
 | | Crystal structure of APC complexed with Asef | | Descriptor: | APC variant protein, Rho guanine nucleotide exchange factor 4 | | Authors: | Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G. | | Deposit date: | 2010-06-23 | | Release date: | 2011-07-06 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.01 Å) | | Cite: | Structural basis for the recognition of Asef by adenomatous polyposis coli.
Cell Res., 22, 2012
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3NMX
 | | Crystal structure of APC complexed with Asef | | Descriptor: | APC variant protein, Rho guanine nucleotide exchange factor 4 | | Authors: | Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G. | | Deposit date: | 2010-06-22 | | Release date: | 2011-07-06 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural basis for the recognition of Asef by adenomatous polyposis coli.
Cell Res., 22, 2012
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5XFS
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5X5M
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7EPW
 | | Crystal structure of monooxygenase Tet(X4) with tigecycline | | Descriptor: | DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, Flavin-dependent monooxygenase, TIGECYCLINE | | Authors: | Cheng, Q, Chen, S. | | Deposit date: | 2021-04-28 | | Release date: | 2021-11-10 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.23 Å) | | Cite: | Structural and mechanistic basis of the high catalytic activity of monooxygenase Tet(X4) on tigecycline.
Bmc Biol., 19, 2021
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7EPV
 | | Crystal structure of tigecycline degrading monooxygenase Tet(X4) | | Descriptor: | DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, Flavin-dependent monooxygenase, GLYCEROL | | Authors: | Cheng, Q, Chen, S. | | Deposit date: | 2021-04-27 | | Release date: | 2021-11-10 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Structural and mechanistic basis of the high catalytic activity of monooxygenase Tet(X4) on tigecycline.
Bmc Biol., 19, 2021
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6JJJ
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8IUF
 | | Cryo-EM structure of Euglena gracilis super-complex I+III2+IV, composite | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ... | | Authors: | Wu, M.C, Tian, H.T, He, Z.X, Hu, Y.Q, Zhou, L. | | Deposit date: | 2023-03-24 | | Release date: | 2024-02-28 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (2.81 Å) | | Cite: | Euglena's atypical respiratory chain adapts to the discoidal cristae and flexible metabolism.
Nat Commun, 15, 2024
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8J9H
 | | Cryo-EM structure of Euglena gracilis respiratory complex I, deactive state | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ... | | Authors: | Wu, M.C, He, Z.X, Tian, H.T, Hu, Y.Q, Han, F.Z, Zhou, L. | | Deposit date: | 2023-05-03 | | Release date: | 2024-02-28 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.11 Å) | | Cite: | Euglena's atypical respiratory chain adapts to the discoidal cristae and flexible metabolism.
Nat Commun, 15, 2024
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8J9I
 | | Cryo-EM structure of Euglena gracilis complex I, turnover state | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... | | Authors: | Wu, M.C, He, Z.X, Tian, H.T, Hu, Y.Q, Han, F.Z, Zhou, L. | | Deposit date: | 2023-05-03 | | Release date: | 2024-02-28 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (2.87 Å) | | Cite: | Euglena's atypical respiratory chain adapts to the discoidal cristae and flexible metabolism.
Nat Commun, 15, 2024
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8J9J
 | | Cryo-EM structure of Euglena gracilis complex I, NADH state | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... | | Authors: | Wu, M.C, He, Z.X, Tian, H.T, Hu, Y.Q, Han, F.Z, Zhou, L. | | Deposit date: | 2023-05-03 | | Release date: | 2024-02-28 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.03 Å) | | Cite: | Euglena's atypical respiratory chain adapts to the discoidal cristae and flexible metabolism.
Nat Commun, 15, 2024
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8IUJ
 | | Cryo-EM structure of Euglena gracilis super-complex III2+IV2, composite | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ... | | Authors: | Wu, M.C, Tian, H.T, He, Z.X, Hu, Y.Q, Zhou, L. | | Deposit date: | 2023-03-24 | | Release date: | 2024-02-28 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.06 Å) | | Cite: | Euglena's atypical respiratory chain adapts to the discoidal cristae and flexible metabolism.
Nat Commun, 15, 2024
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2AX5
 | | Solution Structure of Urm1 from Saccharomyces Cerevisiae | | Descriptor: | Hypothetical 11.0 kDa protein in FAA3-MAS3 intergenic region | | Authors: | Xu, J, Huang, H, Zhang, J, Wu, J, Shi, Y. | | Deposit date: | 2005-09-03 | | Release date: | 2006-06-27 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of Urm1 and its implications for the origin of protein modifiers.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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8UZL
 | | Designed Transmembrane beta-barrel- TMB10_163 | | Descriptor: | Designed Transmembrane beta-barrel TMB10_163, HEXANE-1,6-DIOL | | Authors: | Bera, A.K, Lemma, S.B, Kang, A, Baker, D. | | Deposit date: | 2023-11-15 | | Release date: | 2024-07-17 | | Last modified: | 2024-07-31 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Sculpting conducting nanopore size and shape through de novo protein design.
Science, 385, 2024
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8HEF
 | | The Crystal structure of deuterated S-217622 (Ensitrelvir) bound to the main protease (3CLpro/Mpro) of SARS-CoV-2 | | Descriptor: | 3C-like proteinase, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione, GLYCEROL | | Authors: | Yan, M, Zhang, H. | | Deposit date: | 2022-11-08 | | Release date: | 2023-04-19 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.51 Å) | | Cite: | Synthesis of deuterated S-217622 (Ensitrelvir) with antiviral activity against coronaviruses including SARS-CoV-2.
Antiviral Res., 213, 2023
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8HIV
 | | The structure of apo-SoBcmB with Fe(II) and AKG | | Descriptor: | 2-OXOGLUTARIC ACID, FE (II) ION, Fe/2OG dependent dioxygenase | | Authors: | Wu, L, Zhou, J.H. | | Deposit date: | 2022-11-22 | | Release date: | 2023-07-05 | | Last modified: | 2024-09-04 | | Method: | X-RAY DIFFRACTION (2.2000308 Å) | | Cite: | Enzymatic catalysis favours eight-membered over five-membered ring closure in bicyclomycin biosynthesis
Nat Catal, 6, 2023
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