8Y0N
 
 | | Structure of CXCR3 in complex with VUF11418 and Go (Full map) | | Descriptor: | Antibody fragment ScFv16, C-X-C chemokine receptor type 3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Sano, F.K, Saha, S, Sharma, S, Ganguly, M, Shihoya, W, Nureki, O, Shukla, A.K, Banerjee, R. | | Deposit date: | 2024-01-22 | | Release date: | 2025-02-26 | | Last modified: | 2025-04-09 | | Method: | ELECTRON MICROSCOPY (3.07 Å) | | Cite: | Structural visualization of small molecule recognition by CXCR3 uncovers dual-agonism in the CXCR3-CXCR7 system.
Nat Commun, 16, 2025
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8XYK
 | | Structure of CXCR3 in complex with VUF10661 and Go (Full map) | | Descriptor: | (3~{S})-~{N}-[(2~{S})-6-azanyl-1-(2,2-diphenylethylamino)-1-oxidanylidene-hexan-2-yl]-2-(4-oxidanylidene-4-phenyl-butanoyl)-3,4-dihydro-1~{H}-isoquinoline-3-carboxamide, Antibody fragment ScFv16, C-X-C chemokine receptor type 3, ... | | Authors: | Sano, F.K, Saha, S, Sharma, S, Ganguly, M, Shihoya, W, Nureki, O, Shukla, A.K, Banerjee, R. | | Deposit date: | 2024-01-19 | | Release date: | 2025-02-26 | | Last modified: | 2025-04-09 | | Method: | ELECTRON MICROSCOPY (3.03 Å) | | Cite: | Structural visualization of small molecule recognition by CXCR3 uncovers dual-agonism in the CXCR3-CXCR7 system.
Nat Commun, 16, 2025
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8XXY
 | | Structure of CXCR3 in the apo-state (Receptor focused map) | | Descriptor: | C-X-C chemokine receptor type 3 | | Authors: | Sano, F.K, Saha, S, Sharma, S, Ganguly, M, Shihoya, W, Nureki, O, Shukla, A.K, Banerjee, R. | | Deposit date: | 2024-01-19 | | Release date: | 2025-02-26 | | Last modified: | 2025-04-09 | | Method: | ELECTRON MICROSCOPY (3.68 Å) | | Cite: | Structural visualization of small molecule recognition by CXCR3 uncovers dual-agonism in the CXCR3-CXCR7 system.
Nat Commun, 16, 2025
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8XYI
 | | Structure of CXCR3 in complex with VUF10661 (Receptor-ligand focused map) | | Descriptor: | (3~{S})-~{N}-[(2~{S})-6-azanyl-1-(2,2-diphenylethylamino)-1-oxidanylidene-hexan-2-yl]-2-(4-oxidanylidene-4-phenyl-butanoyl)-3,4-dihydro-1~{H}-isoquinoline-3-carboxamide, C-X-C chemokine receptor type 3 | | Authors: | Sano, F.K, Saha, S, Sharma, S, Ganguly, M, Shihoya, W, Nureki, O, Shukla, A.K, Banerjee, R. | | Deposit date: | 2024-01-19 | | Release date: | 2025-02-26 | | Last modified: | 2025-04-09 | | Method: | ELECTRON MICROSCOPY (3.16 Å) | | Cite: | Structural visualization of small molecule recognition by CXCR3 uncovers dual-agonism in the CXCR3-CXCR7 system.
Nat Commun, 16, 2025
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8XXZ
 | | Structure of CXCR3 in the apo-state (Full map) | | Descriptor: | Antibody fragment ScFv16, C-X-C chemokine receptor type 3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Sano, F.K, Saha, S, Sharma, S, Ganguly, M, Shihoya, W, Nureki, O, Shukla, A.K, Banerjee, R. | | Deposit date: | 2024-01-19 | | Release date: | 2025-02-26 | | Last modified: | 2025-04-09 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural visualization of small molecule recognition by CXCR3 uncovers dual-agonism in the CXCR3-CXCR7 system.
Nat Commun, 16, 2025
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6TKO
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8AS3
 | | Structure of arrestin2 in complex with 6P CCR5 phosphopeptide and Fab30 | | Descriptor: | Beta-arrestin-1, C-C chemokine receptor type 5, Fab30 heavy chain, ... | | Authors: | Isaikina, P, Jakob, R.P, Maier, T, Grzesiek, S. | | Deposit date: | 2022-08-18 | | Release date: | 2023-06-07 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | A key GPCR phosphorylation motif discovered in arrestin2⋅CCR5 phosphopeptide complexes.
Mol.Cell, 83, 2023
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8AS2
 | | Structure of arrestin2 in complex with 4P CCR5 phosphopeptide and Fab30 | | Descriptor: | Beta-arrestin-1, C-C chemokine receptor type 5, Fab30 heavy chain, ... | | Authors: | Isaikina, P, Jakob, R.P, Maier, T, Grzesiek, S. | | Deposit date: | 2022-08-18 | | Release date: | 2023-06-07 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | A key GPCR phosphorylation motif discovered in arrestin2⋅CCR5 phosphopeptide complexes.
Mol.Cell, 83, 2023
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8AS4
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6K3F
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6IBL
 | | ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND AGONIST FORMOTEROL AND NANOBODY Nb80 | | Descriptor: | Camelid antibody fragment Nb80, HEGA-10, SODIUM ION, ... | | Authors: | Warne, T, Edwards, P.C, Dore, A.S, Leslie, A.G.W, Tate, C.G. | | Deposit date: | 2018-11-30 | | Release date: | 2019-01-09 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Molecular basis of beta-arrestin coupling to formoterol-bound beta1-adrenoceptor.
Nature, 583, 2020
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