7S7S
 
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8XWX
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4YE7
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9AZB
 | | Crystal structure of LolTv5 | | Descriptor: | Aminotransferase, class V/Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Gao, J, Hai, Y. | | Deposit date: | 2024-03-11 | | Release date: | 2024-07-17 | | Last modified: | 2024-08-07 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Enzymatic Synthesis of Unprotected alpha , beta-Diamino Acids via Direct Asymmetric Mannich Reactions.
J.Am.Chem.Soc., 146, 2024
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9AZA
 | | Crystal structure of LolTv4 | | Descriptor: | Aminotransferase, class V/Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Gao, J, Hai, Y. | | Deposit date: | 2024-03-10 | | Release date: | 2024-07-17 | | Last modified: | 2024-08-07 | | Method: | X-RAY DIFFRACTION (2.84 Å) | | Cite: | Enzymatic Synthesis of Unprotected alpha , beta-Diamino Acids via Direct Asymmetric Mannich Reactions.
J.Am.Chem.Soc., 146, 2024
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8OVR
 | | Clostridium perfringens chitinase CP56_3454 apo form | | Descriptor: | Chitinase B, PIPERAZINE-N,N'-BIS(2-ETHANESULFONIC ACID), SODIUM ION, ... | | Authors: | Bloch, Y, Savvides, S.N. | | Deposit date: | 2023-04-26 | | Release date: | 2023-07-12 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Clostridium perfringens chitinases, key enzymes during early stages of necrotic enteritis in broiler chickens.
Plos Pathog., 20, 2024
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8OWF
 | | Clostridium perfringens chitinase CP4_3455 with chitosan | | Descriptor: | 2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Chitodextrinase, ... | | Authors: | Bloch, Y, Savvides, S.N. | | Deposit date: | 2023-04-27 | | Release date: | 2023-07-12 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Clostridium perfringens chitinases, key enzymes during early stages of necrotic enteritis in broiler chickens.
Plos Pathog., 20, 2024
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9ARN
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9ARP
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8OXU
 | | Crystal Structure of the Hsp90-LA1011 Complex | | Descriptor: | ATP-dependent molecular chaperone HSP82, dimethyl 2,6-bis[2-(dimethylamino)ethyl]-1-methyl-4-[4-(trifluoromethyl)phenyl]-4~{H}-pyridine-3,5-dicarboxylate | | Authors: | Roe, S.M, Prodromou, C. | | Deposit date: | 2023-05-02 | | Release date: | 2023-07-12 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (2.94 Å) | | Cite: | The Crystal Structure of the Hsp90-LA1011 Complex and the Mechanism by Which LA1011 May Improve the Prognosis of Alzheimer's Disease.
Biomolecules, 13, 2023
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6XR3
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9NRC
 | | TMPRSS6 in complex with REGN7999 Fab and REGN8023 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Saotome, K, Franklin, M.C. | | Deposit date: | 2025-03-14 | | Release date: | 2025-07-09 | | Method: | ELECTRON MICROSCOPY (3.29 Å) | | Cite: | A TMPRSS6-inhibiting mAb improves disease in a beta-thalassemia mouse model and reduces iron in healthy humans.
JCI Insight, 10, 2025
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6XA9
 | | SARS CoV-2 PLpro in complex with ISG15 C-terminal domain propargylamide | | Descriptor: | GLYCEROL, ISG15 CTD-propargylamide, Non-structural protein 3, ... | | Authors: | Klemm, T, Calleja, D.J, Richardson, L.W, Lechtenberg, B.C, Komander, D. | | Deposit date: | 2020-06-04 | | Release date: | 2020-06-17 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2.
Embo J., 39, 2020
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6H6K
 | | The structure of the FKR mutant of the archaeal translation initiation factor 2 gamma subunit in complex with GDPCP, obtained in the absence of magnesium salts in the crystallization solution. | | Descriptor: | 1,2-ETHANEDIOL, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, SODIUM ION, ... | | Authors: | Nikonov, O, Kravchenko, O, Nevskaya, N, Stolboushkina, E, Gabdulkhakov, A, Garber, M, Nikonov, S. | | Deposit date: | 2018-07-27 | | Release date: | 2019-04-17 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The third structural switch in the archaeal translation initiation factor 2 (aIF2) molecule and its possible role in the initiation of GTP hydrolysis and the removal of aIF2 from the ribosome.
Acta Crystallogr D Struct Biol, 75, 2019
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9K0A
 | | Structure of Pictet-Spenglerases KslB in complex with product | | Descriptor: | (1~{S},3~{S})-1-(3-hydroxy-3-oxopropyl)-2,3,4,9-tetrahydropyrido[3,4-b]indole-1,3-dicarboxylic acid, Cucumopine synthase C-terminal helical bundle domain-containing protein, GLYCEROL | | Authors: | Mori, T, Renata, H, Abe, I. | | Deposit date: | 2024-10-15 | | Release date: | 2025-06-18 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | Structure of Pictet-Spenglerases KslB in complex with product
To Be Published
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9MRF
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9MDK
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9MDM
 | | Crystal Structure of C412S Mutant of C0362 (TDE_0362 [TDE0362] resi 205-647) | | Descriptor: | 1,2-ETHANEDIOL, Bacterial Ig-like domain protein C0362, PHOSPHATE ION, ... | | Authors: | Clark, N.D, Malkowski, M.G. | | Deposit date: | 2024-12-05 | | Release date: | 2025-02-12 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | Structural insights into the role of the prosegment binding loop in a papain-superfamily cysteine protease from Treponema denticola.
Acta Crystallogr.,Sect.F, 81, 2025
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9MDO
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9MUP
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9MUA
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7C7J
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7C7I
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7BJ3
 | | ScpA from Streptococcus pyogenes, S512A active site mutant | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, C5a peptidase, CALCIUM ION, ... | | Authors: | Kagawa, T.F, O'Connell, M.R, Cooney, J.C. | | Deposit date: | 2021-01-13 | | Release date: | 2021-05-12 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Enzyme kinetic and binding studies identify determinants of specificity for the immunomodulatory enzyme ScpA, a C5a inactivating bacterial protease.
Comput Struct Biotechnol J, 19, 2021
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7BBM
 | | Mutant nitrobindin M75L/H76L/Q96C/M148L (NB4H) from Arabidopsis thaliana with cofactor MnPPIX | | Descriptor: | 1,2-ETHANEDIOL, MANGANESE PROTOPORPHYRIN IX, UPF0678 fatty acid-binding protein-like protein At1g79260 | | Authors: | Minges, A, Sauer, D.F, Wittwer, M, Markel, U, Spiertz, M, Schiffels, J, Davari, M.D, Okuda, J, Schwaneberg, U, Groth, G. | | Deposit date: | 2020-12-18 | | Release date: | 2021-05-26 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.14 Å) | | Cite: | Chemogenetic engineering of nitrobindin toward an artificial epoxygenase
Catalysis Science And Technology, 2021
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