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7C7I

Crystal structure of SHANK3 SPN domain in complex with GTP-bound Rap1b(E30D,K31E)

Summary for 7C7I
Entry DOI10.2210/pdb7c7i/pdb
DescriptorRas-related protein Rap-1b, SH3 and multiple ankyrin repeat domains protein 3, GUANOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
Functional Keywordsshank3, rap1b, spn, ras, protein binding
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains4
Total formula weight61535.59
Authors
Xiao, L.X.,Pan, L.F. (deposition date: 2020-05-25, release date: 2021-05-05, Last modification date: 2023-11-29)
Primary citationXu, X.L.,Liu, J.P.,Wang, Y.L.,Wang, Y.,Gong, X.,Pan, L.F.
Mechanistic Insights into the Interactions of Ras Subfamily GTPases with the SPN Domain of Autism-associated SHANK3.
Chin.J.Chem., 38:1635-1641, 2020
Cited by
DOI: 10.1002/cjoc.202000278
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.28 Å)
Structure validation

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