7OWN
| HsNMT1 in complex with both MyrCoA and peptide AKSFSKPR | Descriptor: | ALA-LYS-SER-PHE-SER-LYS-PRO-ARG, GLYCEROL, Glycylpeptide N-tetradecanoyltransferase 1, ... | Authors: | Dian, C, Giglione, C, Meinnel, T. | Deposit date: | 2021-06-18 | Release date: | 2022-12-21 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and Large-scale Analysis Unveil the Intertwined Paths Promoting NMT-catalyzed Lysine and Glycine Myristoylation. J.Mol.Biol., 434, 2022
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7OWM
| HsNMT1 in complex with both MyrCoA and HCPA substrate peptide GKQNSKLR | Descriptor: | GLYCEROL, Glycylpeptide N-tetradecanoyltransferase 1, Neuron-specific calcium-binding protein hippocalcin, ... | Authors: | Dian, C, Giglione, C, Meinnel, T. | Deposit date: | 2021-06-18 | Release date: | 2022-12-21 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural and Large-scale Analysis Unveil the Intertwined Paths Promoting NMT-catalyzed Lysine and Glycine Myristoylation. J.Mol.Biol., 434, 2022
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7R4K
| Crystal structure of human mitochondrial NAD kinase | Descriptor: | MAGNESIUM ION, NAD kinase 2, mitochondrial, ... | Authors: | Labesse, G, Mary, C, Gelin, M, Lionne, C. | Deposit date: | 2022-02-08 | Release date: | 2022-07-06 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3.33 Å) | Cite: | Crystal structure of human NADK2 reveals a dimeric organization and active site occlusion by lysine acetylation. Mol.Cell, 82, 2022
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7R4J
| Crystal structure of human mitochondrial NAD kinase | Descriptor: | CALCIUM ION, NAD kinase 2, mitochondrial | Authors: | Labesse, G, Mary, C, Gelin, M, Lionne, C. | Deposit date: | 2022-02-08 | Release date: | 2022-07-06 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Crystal structure of human NADK2 reveals a dimeric organization and active site occlusion by lysine acetylation. Mol.Cell, 82, 2022
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7R4L
| Crystal structure of human mitochondrial NAD kinase | Descriptor: | FE (III) ION, NAD kinase 2, mitochondrial, ... | Authors: | Labesse, G, Mary, C, Gelin, M, Lionne, C. | Deposit date: | 2022-02-08 | Release date: | 2022-07-06 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of human NADK2 reveals a dimeric organization and active site occlusion by lysine acetylation. Mol.Cell, 82, 2022
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7R4M
| Crystal structure of mitochondrial NAD kinase | Descriptor: | CALCIUM ION, NAD kinase 2, mitochondrial, ... | Authors: | Labesse, G, Mary, C, Gelin, M, Lionne, C. | Deposit date: | 2022-02-08 | Release date: | 2022-07-06 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Crystal structure of human NADK2 reveals a dimeric organization and active site occlusion by lysine acetylation. Mol.Cell, 82, 2022
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4JE7
| Crystal structure of a human-like mitochondrial peptide deformylase in complex with actinonin | Descriptor: | ACTINONIN, Peptide deformylase 1A, chloroplastic/mitochondrial, ... | Authors: | Fieulaine, S, Meinnel, T, Giglione, C. | Deposit date: | 2013-02-26 | Release date: | 2014-02-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Understanding the highly efficient catalysis of prokaryotic peptide deformylases by shedding light on the determinants specifying the low activity of the human counterpart. Acta Crystallogr.,Sect.D, 70, 2014
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6SK2
| HsNMT1 in complex with both MyrCoA and Acetylated-GKSFSKPR peptide reveals N-terminal Lysine Myristoylation | Descriptor: | Apoptosis-inducing factor 3, COENZYME A, GLYCEROL, ... | Authors: | Dian, C, Riviere, F.B, Asensio, T, Giglione, C, Meinnel, T. | Deposit date: | 2019-08-14 | Release date: | 2020-03-18 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.90000653 Å) | Cite: | High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation. Nat Commun, 11, 2020
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6SKJ
| DeltaC2 C-terminal truncation of HsNMT1 in complex with MyrCoA and GNCFSKPR substrates | Descriptor: | Apoptosis-inducing factor 3, COENZYME A, GLYCEROL, ... | Authors: | Dian, C, Riviere, F.B, Asensio, T, Giglione, C, Meinnel, T. | Deposit date: | 2019-08-15 | Release date: | 2020-03-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation. Nat Commun, 11, 2020
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6SK8
| DeltaC3 C-terminal truncation of HsNMT1 in complex with MyrCoA and GDCFSKPR substrates | Descriptor: | Apoptosis-inducing factor 3, CHLORIDE ION, GLYCEROL, ... | Authors: | Dian, C, Riviere, F.B, Asensio, T, Giglione, C, Meinnel, T. | Deposit date: | 2019-08-14 | Release date: | 2020-03-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation. Nat Commun, 11, 2020
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6SJZ
| HsNMT1 in complex with both MyrCoA and Acetylated-GNCFSKPR substrates | Descriptor: | Apoptosis-inducing factor 3, CHLORIDE ION, GLYCEROL, ... | Authors: | Dian, C, Riviere, F.B, Asensio, T, Giglione, C, Meinnel, T. | Deposit date: | 2019-08-14 | Release date: | 2020-03-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.995 Å) | Cite: | High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation. Nat Commun, 11, 2020
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6SK3
| C-terminal HsNMT1 deltaC3 truncation in complex with both MyrCoA and GNCFSKPR substrates | Descriptor: | Apoptosis-inducing factor 3, GLYCEROL, Glycylpeptide N-tetradecanoyltransferase 1, ... | Authors: | Dian, C, Riviere, F.B, Asensio, T, Giglione, C, Meinnel, T. | Deposit date: | 2019-08-14 | Release date: | 2020-03-18 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation. Nat Commun, 11, 2020
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3O3J
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3M6P
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3PN4
| Crystal structure of Arabidopsis thaliana petide deformylase 1B (AtPDF1B) in complex with actinonin (crystallized in PEG-550-MME) | Descriptor: | ACTINONIN, Peptide deformylase 1B, chloroplastic, ... | Authors: | Fieulaine, S, Meinnel, T, Giglione, C. | Deposit date: | 2010-11-18 | Release date: | 2011-06-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Trapping conformational States along ligand-binding dynamics of Peptide deformylase: the impact of induced fit on enzyme catalysis. Plos Biol., 9, 2011
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3PN2
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3PN6
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3PN5
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3PN3
| Crystal structure of Arabidopsis thaliana petide deformylase 1B (AtPDF1B) in complex with inhibitor 21 | Descriptor: | Peptide deformylase 1B, chloroplastic, ZINC ION, ... | Authors: | Fieulaine, S, Meinnel, T, Giglione, C. | Deposit date: | 2010-11-18 | Release date: | 2011-06-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Trapping conformational States along ligand-binding dynamics of Peptide deformylase: the impact of induced fit on enzyme catalysis. Plos Biol., 9, 2011
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2MGV
| NMR structure of PASTA domain of PonA2 from Mycobacterium tuberculosis | Descriptor: | Bifunctional membrane-associated penicillin-binding protein 1A/1B ponA2 | Authors: | Calvanese, L, Falcigno, L, Maglione, C, Marasco, D, Ruggiero, A, Squeglia, F, Berisio, R, D'Auria, G. | Deposit date: | 2013-11-11 | Release date: | 2013-12-25 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural and binding properties of the PASTA domain of PonA2, a key penicillin binding protein from Mycobacterium tuberculosis. Biopolymers, 101, 2014
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7QVS
| Pseudomonas aeruginosa nicotinamide adenine dinucleotide kinase (NADK) structure in complex with NADP | Descriptor: | NAD kinase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PHOSPHATE ION | Authors: | Rahimova, R, Gelin, M, Labesse, G, Lionne, C. | Deposit date: | 2022-01-23 | Release date: | 2022-09-14 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure-based design, synthesis and biological evaluation of a NAD + analogue targeting Pseudomonas aeruginosa NAD kinase. Febs J., 290, 2023
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1SWM
| X-RAY CRYSTAL STRUCTURE OF THE FERRIC SPERM WHALE MYOGLOBIN: IMIDAZOLE COMPLEX AT 2.0 ANGSTROMS RESOLUTION | Descriptor: | AZIDE ION, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Rizzi, M, Ascenzi, P, Coda, A, Brunori, M, Bolognesi, M. | Deposit date: | 1992-03-03 | Release date: | 1994-01-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | X-ray crystal structure of the ferric sperm whale myoglobin: imidazole complex at 2.0 A resolution. J.Mol.Biol., 217, 1991
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7ZF2
| Protomeric substructure from an octameric assembly of M. tuberculosis RNA polymerase in complex with sigma-b initiation factor | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Trapani, S, Bron, P, Lai Kee Him, J, Brodolin, K, Morichaud, Z, Vishwakarma, R. | Deposit date: | 2022-03-31 | Release date: | 2023-02-08 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.86 Å) | Cite: | Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization. Nat Commun, 14, 2023
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7Z8Q
| Cryo-EM structure of Mycobacterium tuberculosis RNA polymerase core | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Brodolin, K. | Deposit date: | 2022-03-18 | Release date: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (4.08 Å) | Cite: | Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization Nat Commun, 14, 2023
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5CR7
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