4JE7

Crystal structure of a human-like mitochondrial peptide deformylase in complex with actinonin

Summary for 4JE7

Entry DOI	10.2210/pdb4je7/pdb
Related	4JE6 4JE8
Descriptor	Peptide deformylase 1A, chloroplastic/mitochondrial, ACTINONIN, ZINC ION, ... (4 entities in total)
Functional Keywords	peptide deformylase, mitochondrial, actinonin, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Arabidopsis thaliana (mouse-ear cress,thale-cress)
Cellular location	Plastid, chloroplast stroma: Q9FV53
Total number of polymer chains	2
Total formula weight	45647.29
Authors	Fieulaine, S.,Meinnel, T.,Giglione, C. (deposition date: 2013-02-26, release date: 2014-02-26, Last modification date: 2023-11-08)
Primary citation	Fieulaine, S.,Desmadril, M.,Meinnel, T.,Giglione, C. Understanding the highly efficient catalysis of prokaryotic peptide deformylases by shedding light on the determinants specifying the low activity of the human counterpart. Acta Crystallogr.,Sect.D, 70:242-252, 2014 Cited by PubMed: 24531459 DOI: 10.1107/S1399004713026461 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation