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2M03
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BU of 2m03 by Molmil
Solution structure of BCL-xL determined with selective isotope labelling of I,L,V sidechains
Descriptor: Bcl-2-like protein 1
Authors:Viacava Follis, A, Royappa, G, Kriwacki, R.W.
Deposit date:2012-10-19
Release date:2013-01-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis.
Nat.Chem.Biol., 9, 2013
2MAH
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BU of 2mah by Molmil
Solution structure of Smoothened
Descriptor: Protein smoothened
Authors:Rana, R, Lee, H, Zheng, J.J.
Deposit date:2013-07-09
Release date:2014-03-05
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural insights into the role of the Smoothened cysteine-rich domain in Hedgehog signalling.
Nat Commun, 4, 2013
2MT5
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BU of 2mt5 by Molmil
Isolated Ring domain
Descriptor: Anaphase-promoting complex subunit 11, ZINC ION
Authors:Brown, N.G, Watson, E.R, Weissman, F, Royappa, G, Schulman, B, Jarvis, M, Vanderlinden, R, Frye, J.J, Qiao, R, Petzold, G, Peters, J, Stark, H.
Deposit date:2014-08-13
Release date:2014-10-29
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Mechanism of Polyubiquitination by Human Anaphase-Promoting Complex: RING Repurposing for Ubiquitin Chain Assembly.
Mol.Cell, 56, 2014
2M6N
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BU of 2m6n by Molmil
3D solution structure of EMI1 (Early Mitotic Inhibitor 1)
Descriptor: F-box only protein 5, ZINC ION
Authors:Frye, J.J, Brown, N.G, Petzold, G, Watson, E.R, Royappa, G.R, Nourse, A, Jarvis, M, Kriwacki, R.W, Peters, J, Stark, H, Schulman, B.A.
Deposit date:2013-04-06
Release date:2013-05-29
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Electron microscopy structure of human APC/C(CDH1)-EMI1 reveals multimodal mechanism of E3 ligase shutdown.
Nat.Struct.Mol.Biol., 20, 2013
2M04
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BU of 2m04 by Molmil
Solution structure of BCL-xL in complex with PUMA BH3 peptide
Descriptor: Bcl-2-binding component 3, Bcl-2-like protein 1
Authors:Viacava Follis, A, Royappa, G, Kriwacki, R.W.
Deposit date:2012-10-19
Release date:2013-01-30
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis.
Nat.Chem.Biol., 9, 2013
7SG3
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BU of 7sg3 by Molmil
The X-ray crystal structure of the Staphylococcus aureus Fatty Acid Kinase B1 mutant A121I-A158L to 2.35 Angstrom resolution (Open form chain A, Palmitate bound)
Descriptor: Fatty Acid Kinase B1, PALMITIC ACID
Authors:Cuypers, M.G, Gullett, J.M, Rock, C.O, White, S.W.
Deposit date:2021-10-04
Release date:2021-10-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Identification of structural transitions in bacterial fatty acid binding proteins that permit ligand entry and exit at membranes.
J.Biol.Chem., 298, 2022
7SCL
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BU of 7scl by Molmil
The X-ray crystal structure of Staphylococcus aureus Fatty Acid Kinase B1 (FakB1) mutant R173A in complex with Palmitate to 1.60 Angstrom resolution
Descriptor: Fatty Acid Kinase B1, GLYCEROL, PALMITIC ACID
Authors:Cuypers, M.G, Gullett, J.M, Subramanian, C, Rock, C.O, White, S.W.
Deposit date:2021-09-28
Release date:2021-10-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Identification of structural transitions in bacterial fatty acid binding proteins that permit ligand entry and exit at membranes.
J.Biol.Chem., 298, 2022
2ME8
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BU of 2me8 by Molmil
Solution Structure of BCL-xL in its p53-bound conformation determined with selective isotope labelling of I,L,V sidechains
Descriptor: Bcl-2-like protein 1
Authors:Viacava Follis, A, Grace, C.R, Kriwacki, R.W.
Deposit date:2013-09-25
Release date:2014-04-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The DNA-binding domain mediates both nuclear and cytosolic functions of p53.
Nat.Struct.Mol.Biol., 21, 2014
2ME9
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BU of 2me9 by Molmil
Solution structure of BCL-xL containing the alpha1-alpha2 disordered loop determined with selective isotope labelling of I,L,V sidechains
Descriptor: Bcl-2-like protein 1
Authors:Viacava Follis, A, Grace, C.R, Kriwacki, R.W.
Deposit date:2013-09-25
Release date:2014-04-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The DNA-binding domain mediates both nuclear and cytosolic functions of p53.
Nat.Struct.Mol.Biol., 21, 2014
2MEJ
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BU of 2mej by Molmil
Solution Structure of the Complex Between BCL-xL and the p53 Core Domain determined with PRE restraints
Descriptor: Bcl-2-like protein 1, Cellular tumor antigen p53, ZINC ION
Authors:Viacava Follis, A, Grace, C.R, Kriwacki, R.W.
Deposit date:2013-09-25
Release date:2014-04-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The DNA-binding domain mediates both nuclear and cytosolic functions of p53.
Nat.Struct.Mol.Biol., 21, 2014
6NXL
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BU of 6nxl by Molmil
Ubiquitin binding variants
Descriptor: Polyubiquitin-B
Authors:Miller, D.J, Watson, E.R.
Deposit date:2019-02-08
Release date:2020-01-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.803 Å)
Cite:Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site.
Proc.Natl.Acad.Sci.USA, 116, 2019
6NXK
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BU of 6nxk by Molmil
Ubiquitin binding variants
Descriptor: Anaphase-promoting complex subunit 2, Polyubiquitin-C
Authors:Miller, D.J, Watson, E.R.
Deposit date:2019-02-08
Release date:2020-01-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site.
Proc.Natl.Acad.Sci.USA, 116, 2019
6OJJ
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BU of 6ojj by Molmil
Structure of ScAtg3 with truncations in N-terminal and flexible region (FR)
Descriptor: Autophagy-related protein 3,Autophagy-related protein 3, GLYCEROL
Authors:Zheng, Y, Qiu, Y, Schulman, B.A.
Deposit date:2019-04-11
Release date:2019-08-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.406 Å)
Cite:A switch element in the autophagy E2 Atg3 mediates allosteric regulation across the lipidation cascade.
Nat Commun, 10, 2019
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