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5KG5
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BU of 5kg5 by Molmil
Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 10 mM Cd2+ for 60s
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KFB
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BU of 5kfb by Molmil
Human DNA polymerase eta-DNA ternary complex: reaction with 1 mM Mn2+ for 90s
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KFM
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BU of 5kfm by Molmil
Human DNA polymerase eta-DNA ternary complex with Sp-dATP-alpha-S: ground state at pH7.0 (K+ MES) with 1 Ca2+ ion
Descriptor: 2'-DEOXYADENOSINE 5'-O-(1-THIOTRIPHOSPHATE), CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KFW
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BU of 5kfw by Molmil
Human DNA polymerase eta R61A-DNA ternary complex: reaction with 1 mM Mg2+ for 200s
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KFY
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BU of 5kfy by Molmil
Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 5 mM Mn2+ for 60s at 4 degree
Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Gao, Y, Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
6M71
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BU of 6m71 by Molmil
SARS-Cov-2 RNA-dependent RNA polymerase in complex with cofactors
Descriptor: Non-structural protein 7, Non-structural protein 8, RNA-directed RNA polymerase
Authors:Gao, Y, Yan, L, Huang, Y, Liu, F, Cao, L, Wang, T, Wang, Q, Lou, Z, Rao, Z.
Deposit date:2020-03-16
Release date:2020-04-01
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure of the RNA-dependent RNA polymerase from COVID-19 virus.
Science, 368, 2020
7JSN
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BU of 7jsn by Molmil
Structure of the Visual Signaling Complex between Transducin and Phosphodiesterase 6
Descriptor: 2-{2-ETHOXY-5-[(4-ETHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-5-METHYL-7-PROPYLIMIDAZO[5,1-F][1,2,4]TRIAZIN-4(1H)-ONE, GUANOSINE-3',5'-MONOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Gao, Y, Eskici, G, Ramachandran, S, Skiniotis, G, Cerione, R.A.
Deposit date:2020-08-15
Release date:2020-10-21
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of the Visual Signaling Complex between Transducin and Phosphodiesterase 6.
Mol.Cell, 80, 2020
4GX3
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BU of 4gx3 by Molmil
Product Complexes of Porcine Liver Fructose-1,6-bisphosphatase with mutation R22M Reveal a T-state Conformation
Descriptor: 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase 1, MAGNESIUM ION, ...
Authors:Gao, Y, Honzatko, R.B.
Deposit date:2012-09-03
Release date:2013-09-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Dimer-dimer Interface in Porcine Liver Fructose-1,6-bisphosphatase is Essential in Cooperative Binding of AMP
To be Published
4GWX
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BU of 4gwx by Molmil
Crystal Structure of product complexes of Porcine Liver Fructose-1,6-bisphosphatase with restrained subunit pair rotation
Descriptor: 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase 1, MAGNESIUM ION, ...
Authors:Gao, Y, Honzatko, R.B.
Deposit date:2012-09-03
Release date:2013-09-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Functional Importance of Subunit Pair Rotation in Regulation of Tetrameric Mammalian Fructose-1,6-bisphosphatase
To be Published
4GX4
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BU of 4gx4 by Molmil
AMP Complexes of Porcine Liver Fructose-1,6-bisphosphatase with mutation R22M
Descriptor: 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase 1, ...
Authors:Gao, Y, Honzatko, R.B.
Deposit date:2012-09-03
Release date:2013-09-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Dimer-dimer Interface in Porcine Liver Fructose-1,6-bisphosphatase is Essential in Cooperative Binding of AMP
To be Published
4GWS
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BU of 4gws by Molmil
Crystal Structure of AMP complexes of Porcine Liver Fructose-1,6-bisphosphatase with Filled Central Cavity
Descriptor: 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase 1, ...
Authors:Gao, Y, Honzatko, R.B.
Deposit date:2012-09-03
Release date:2013-09-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Hydrophobic Central Cavity in Fructose-1,6-bisphosphatase is Essential for the Synergism in AMP/Fructose 2,6-bisphosphate Inhibition
To be Published
4GWZ
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BU of 4gwz by Molmil
Crystal Structure of AMP Complexes of Porcine Liver Fructose-1,6-bisphosphatase with Restrained Subunit Pair Rotation
Descriptor: 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase 1, ...
Authors:Gao, Y, Honzatko, R.B.
Deposit date:2012-09-03
Release date:2013-09-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Functional Importance of Subunit Pair Rotation in Regulation of Tetrameric Mammalian Fructose-1,6-bisphosphatase
To be Published
4GWU
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BU of 4gwu by Molmil
Crystal Structure of Fru 2,6-bisphosphate complexes of Porcine Liver Fructose-1,6-bisphosphatase with Filled Central Cavity
Descriptor: 2,6-di-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase 1, MAGNESIUM ION
Authors:Gao, Y, Honzatko, R.B.
Deposit date:2012-09-03
Release date:2013-09-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Hydrophobic Central Cavity in Fructose-1,6-bisphosphatase is Essential for the Synergism in AMP/Fru 2,6-bisphosphate Inhibition
To be Published
4GWY
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BU of 4gwy by Molmil
Crystal Structure of AMP Complexes of Porcine Liver Fructose-1,6-bisphosphatase with Blocked Subunit Pair Rotation
Descriptor: 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase 1, ...
Authors:Gao, Y, Honzatko, R.B.
Deposit date:2012-09-03
Release date:2013-09-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Functional Importance of Subunit Pair Rotation in Regulation of Tetrameric Mammalian Fructose-1,6-bisphosphatase
To be Published
4GWW
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BU of 4gww by Molmil
Crystal Structure of product complexes of Porcine Liver Fructose-1,6-bisphosphatase with blocked subunit pair rotation
Descriptor: 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase 1, MAGNESIUM ION, ...
Authors:Gao, Y, Honzatko, R.B.
Deposit date:2012-09-03
Release date:2013-09-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Functional Importance of Subunit Pair Rotation in Regulation of Tetrameric Mammalian Fructose-1,6-bisphosphatase
To be Published
4GX6
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BU of 4gx6 by Molmil
AMP Complexes of Porcine Liver Fructose-1,6-bisphosphatase with Mutation E192Q
Descriptor: 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase 1, ...
Authors:Gao, Y, Honzatko, R.B.
Deposit date:2012-09-03
Release date:2013-09-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Dimer-dimer Interface in Porcine Liver Fructose-1,6-bisphosphatase is Essential in Cooperative Binding of AMP
To be Published
4H46
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BU of 4h46 by Molmil
Crystal Structure of AMP complexes of NEM modified Porcine Liver Fructose-1,6-bisphosphatase
Descriptor: 1-ETHYL-PYRROLIDINE-2,5-DIONE, 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, ...
Authors:Gao, Y, Honzatko, R.B.
Deposit date:2012-09-16
Release date:2013-09-18
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Fluorescent 2',3'-O-(2,4,6-trinitrophenyl) (TNP)-AMP Is an Active Site Inhibitor for Porcine Liver Fructose-1,6-bisphosphatase Rather Than Allosteric Inhibitor
To be Published
4H45
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BU of 4h45 by Molmil
Product Complexes of Porcine Liver Fructose-1,6-bisphosphatase with Mutation E192Q
Descriptor: 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase 1, PHOSPHATE ION, ...
Authors:Gao, Y, Honzatko, R.B.
Deposit date:2012-09-16
Release date:2013-09-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Dimer-dimer Interface in Porcine Liver Fructose-1,6-bisphosphatase is Essential in Cooperative Binding of AMP
To be Published
6N7I
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BU of 6n7i by Molmil
Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (gp4(5)-DNA)
Descriptor: DNA (25-MER), DNA primase/helicase, MAGNESIUM ION, ...
Authors:Gao, Y, Cui, Y, Zhou, Z, Yang, W.
Deposit date:2018-11-27
Release date:2019-03-06
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structures and operating principles of the replisome.
Science, 363, 2019
6N9U
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BU of 6n9u by Molmil
Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) interacting with primase domains of two gp4 subunits bound to an RNA/DNA hybrid and dTTP (from LagS1)
Descriptor: DNA (44-MER), DNA primase/helicase, DNA-directed DNA polymerase, ...
Authors:Gao, Y, Fox, T, Val, N, Yang, W.
Deposit date:2018-12-04
Release date:2019-03-06
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structures and operating principles of the replisome.
Science, 363, 2019
6N7T
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BU of 6n7t by Molmil
Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form III)
Descriptor: DNA (25-MER), DNA primase/helicase, MAGNESIUM ION, ...
Authors:Gao, Y, Cui, Y, Zhou, Z, Yang, W.
Deposit date:2018-11-28
Release date:2019-03-06
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structures and operating principles of the replisome.
Science, 363, 2019
6N9X
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BU of 6n9x by Molmil
Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS3)
Descriptor: DNA primase/helicase, DNA-directed DNA polymerase, MAGNESIUM ION, ...
Authors:Gao, Y, Fox, T, Val, N, Yang, W.
Deposit date:2018-12-04
Release date:2019-03-06
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structures and operating principles of the replisome.
Science, 363, 2019
6N7S
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BU of 6n7s by Molmil
Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form II)
Descriptor: DNA (25-MER), DNA primase/helicase, MAGNESIUM ION, ...
Authors:Gao, Y, Cui, Y, Zhou, Z, Yang, W.
Deposit date:2018-11-28
Release date:2019-03-06
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structures and operating principles of the replisome.
Science, 363, 2019
6N9W
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BU of 6n9w by Molmil
Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS2)
Descriptor: DNA primase/helicase, DNA-directed DNA polymerase, MAGNESIUM ION, ...
Authors:Gao, Y, Cui, Y, Zhou, Z, Yang, W.
Deposit date:2018-12-04
Release date:2019-03-06
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structures and operating principles of the replisome.
Science, 363, 2019
6N7V
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BU of 6n7v by Molmil
Structure of bacteriophage T7 gp4 (helicase-primase, E343Q mutant) in complex with ssDNA, dTTP, AC dinucleotide, and CTP (from multiple lead complexes)
Descriptor: DNA (93-MER), DNA primase/helicase, MAGNESIUM ION, ...
Authors:Gao, Y, Fox, T, Val, N, Yang, W.
Deposit date:2018-11-28
Release date:2019-03-06
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structures and operating principles of the replisome.
Science, 363, 2019

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PDB entries from 2024-10-16

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