7TER
 
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7TEB
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7TEE
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7TE6
 | | Crystal structure of GluN1b-2B ATD complexed to Fab5 anti-GluN2B antibody | | Descriptor: | Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ... | | Authors: | Regan, M, Tajima, N, Furukawa, H. | | Deposit date: | 2022-01-04 | | Release date: | 2022-03-02 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (4.55 Å) | | Cite: | Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
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7TET
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7TEQ
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8VUJ
 | | Human GluN1-2A with Fab 003-102 | | Descriptor: | 003-102 Heavy, 003-102 Light, Glutamate receptor ionotropic, ... | | Authors: | Michalski, K, Furukawa, H. | | Deposit date: | 2024-01-29 | | Release date: | 2024-09-11 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.92 Å) | | Cite: | Structural and functional mechanisms of anti-NMDAR autoimmune encephalitis.
Nat.Struct.Mol.Biol., 2024
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8VVH
 | | rat GluN1a-2B Fab 003-102 local refinement | | Descriptor: | 003-102 Heavy, 003-102 Light, Glutamate receptor ionotropic, ... | | Authors: | Michalski, K, Furukawa, H. | | Deposit date: | 2024-01-31 | | Release date: | 2024-09-11 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.95 Å) | | Cite: | Structural and functional mechanisms of anti-NMDAR autoimmune encephalitis.
Nat.Struct.Mol.Biol., 2024
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8VUQ
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8VUV
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8VUT
 | | Human GluN1-2A with IgG 008-218 | | Descriptor: | 008-218 Heavy, 008-218 Light, Glutamate receptor ionotropic, ... | | Authors: | Michalski, K, Furukawa, H. | | Deposit date: | 2024-01-29 | | Release date: | 2024-09-11 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural and functional mechanisms of anti-NMDAR autoimmune encephalitis.
Nat.Struct.Mol.Biol., 2024
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8VUH
 | | Human GluN1-2A IgG 003-102 splayed conformation | | Descriptor: | 003-102 Heavy, 003-102 Light, Glutamate receptor ionotropic, ... | | Authors: | Michalski, K, Furukawa, H. | | Deposit date: | 2024-01-29 | | Release date: | 2024-09-11 | | Last modified: | 2024-09-18 | | Method: | ELECTRON MICROSCOPY (4.42 Å) | | Cite: | Structural and functional mechanisms of anti-NMDAR autoimmune encephalitis.
Nat.Struct.Mol.Biol., 2024
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8VUL
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8VUU
 | | Human GluN1-2B with Fab 007-168 | | Descriptor: | 007-168 Heavy, 007-168 Light, Glutamate receptor ionotropic, ... | | Authors: | Michalski, K, Furukawa, H. | | Deposit date: | 2024-01-29 | | Release date: | 2024-09-11 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (4.05 Å) | | Cite: | Structural and functional mechanisms of anti-NMDAR autoimmune encephalitis.
Nat.Struct.Mol.Biol., 2024
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8VUS
 | | Human GluN1-2A with IgG 007-168 | | Descriptor: | 007-168 Heavy, 007-168 Light, Glutamate receptor ionotropic, ... | | Authors: | Michalski, K, Furukawa, H. | | Deposit date: | 2024-01-29 | | Release date: | 2024-09-11 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.99 Å) | | Cite: | Structural and functional mechanisms of anti-NMDAR autoimmune encephalitis.
Nat.Struct.Mol.Biol., 2024
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8VUR
 | | Human GluN1-2A with IgG 003-102 WT conformation | | Descriptor: | 003-102 Heavy, 003-102 Light, Glutamate receptor ionotropic, ... | | Authors: | Michalski, K, Furukawa, H. | | Deposit date: | 2024-01-29 | | Release date: | 2024-09-11 | | Last modified: | 2024-09-18 | | Method: | ELECTRON MICROSCOPY (3.84 Å) | | Cite: | Structural and functional mechanisms of anti-NMDAR autoimmune encephalitis.
Nat.Struct.Mol.Biol., 2024
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8VUY
 | | Rat GluN1-2B with Fab 003-102 | | Descriptor: | 003-102 Heavy, 003-102 Light, Glutamate receptor ionotropic, ... | | Authors: | Michalski, K, Furukawa, H. | | Deposit date: | 2024-01-30 | | Release date: | 2024-09-11 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.81 Å) | | Cite: | Structural and functional mechanisms of anti-NMDAR autoimmune encephalitis.
Nat.Struct.Mol.Biol., 2024
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8VUN
 | | Human GluN1-2A With Fab 008-218 | | Descriptor: | 008-218 Heavy, 008-218 Light, Glutamate receptor ionotropic, ... | | Authors: | Michalski, K, Furukawa, H. | | Deposit date: | 2024-01-29 | | Release date: | 2024-09-11 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (4.01 Å) | | Cite: | Structural and functional mechanisms of anti-NMDAR autoimmune encephalitis.
Nat.Struct.Mol.Biol., 2024
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3QEM
 | | Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2B in complex with Ro 25-6981 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol, Glutamate [NMDA] receptor subunit epsilon-2, ... | | Authors: | Karakas, E, Simorowski, N, Furukawa, H. | | Deposit date: | 2011-01-20 | | Release date: | 2011-06-15 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (3.003 Å) | | Cite: | Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors.
Nature, 475, 2011
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3QEL
 | | Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2B in complex with ifenprodil | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(1R,2S)-2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl]phenol, Glutamate [NMDA] receptor subunit epsilon-2, ... | | Authors: | Karakas, E, Simorowski, N, Furukawa, H. | | Deposit date: | 2011-01-20 | | Release date: | 2011-06-15 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors.
Nature, 475, 2011
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3OEL
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3OEK
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3OEN
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3QEK
 | | Crystal structure of amino terminal domain of the NMDA receptor subunit GluN1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, NMDA glutamate receptor subunit, POTASSIUM ION, ... | | Authors: | Karakas, E, Simorowski, N, Furukawa, H. | | Deposit date: | 2011-01-20 | | Release date: | 2011-06-15 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.001 Å) | | Cite: | Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors.
Nature, 475, 2011
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4NF5
 | | Crystal structure of GluN1/GluN2A ligand-binding domain in complex with glycine and D-AP5 | | Descriptor: | 5-phosphono-D-norvaline, GLYCEROL, GLYCINE, ... | | Authors: | Jespersen, A, Tajima, N, Furukawa, H. | | Deposit date: | 2013-10-30 | | Release date: | 2014-03-12 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.903 Å) | | Cite: | Structural Insights into Competitive Antagonism in NMDA Receptors.
Neuron, 81, 2014
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