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2BJW
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BU of 2bjw by Molmil
PspF AAA domain
Descriptor: PSP OPERON TRANSCRIPTIONAL ACTIVATOR
Authors:Rappas, M, Schumacher, J, Beuron, F, Niwa, H, Bordes, P, Wigneshweraraj, S, Keetch, C.A, Robinson, C.V, Buck, M, Zhang, X.
Deposit date:2005-02-08
Release date:2005-03-31
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Insights Into the Activity of Enhancer-Binding Proteins
Science, 307, 2005
2C96
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BU of 2c96 by Molmil
Structural basis of the nucleotide driven conformational changes in the AAA domain of transcription activator PspF
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, PSP OPERON TRANSCRIPTIONAL ACTIVATOR
Authors:Rappas, M, Schumacher, J, Niwa, H, Buck, M, Zhang, X.
Deposit date:2005-12-09
Release date:2006-02-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis of the Nucleotide Driven Conformational Changes in the Aaa(+) Domain of Transcription Activator Pspf.
J.Mol.Biol., 357, 2006
3NQW
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BU of 3nqw by Molmil
A metazoan ortholog of SpoT hydrolyzes ppGpp and plays a role in starvation responses
Descriptor: CG11900, MANGANESE (II) ION, SULFATE ION
Authors:Sun, D.W, Kim, H.Y, Kim, K.J, Jeon, Y.H, Chung, J.
Deposit date:2010-06-30
Release date:2010-09-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A metazoan ortholog of SpoT hydrolyzes ppGpp and functions in starvation responses
Nat.Struct.Mol.Biol., 17, 2010
4BGH
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BU of 4bgh by Molmil
Crystal Structure of CDK2 in complex with pan-CDK Inhibitor
Descriptor: 4-((5-BROMO-4-(PROP-2-YN-1-YLAMINO)PYRIMIDIN-2-YL)AMINO)BENZENESULFONAMIDE, CYCLIN-DEPENDENT KINASE 2
Authors:Luecking, U, Jautelat, R, Krueger, M, Brumby, T, Lienau, P, Schaefer, M, Briem, H, Schulze, J, Hillisch, A, Reichel, A, Siemeister, G.
Deposit date:2013-03-26
Release date:2013-09-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The Lab Oddity Prevails: Discovery of Pan-Cdk Inhibitor (R)- S-Cyclopropyl-S-(4-{[4-{[(1R,2R)-2-Hydroxy-1-Methylpropyl]Oxy}-5-(Trifluoromethyl)Pyrimidin-2-Yl]Amino}Phenyl)Sulfoximide (Bay 1000394) for the Treatment of Cancer.
Chemmedchem, 8, 2013
2K1F
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BU of 2k1f by Molmil
SUMO-3 from Drosophila melanogaster (dsmt3)
Descriptor: CG4494-PA
Authors:Kumar, D, Misra, J.R, Misra, A.K, Chugh, J, Sharma, S, Hosur, R.V.
Deposit date:2008-03-03
Release date:2009-03-10
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:NMR-derived solution structure of SUMO from Drosophila melanogaster (dSmt3).
Proteins, 75, 2009
2KO2
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BU of 2ko2 by Molmil
NOGO66
Descriptor: Reticulon-4
Authors:Cocco, M.J, Schulz, J, Vasudevan, S.V.
Deposit date:2009-09-08
Release date:2010-04-21
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Protein folding at the membrane interface, the structure of Nogo-66 requires interactions with a phosphocholine surface.
Proc.Natl.Acad.Sci.USA, 107, 2010
1KBH
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BU of 1kbh by Molmil
Mutual Synergistic Folding in the Interaction Between Nuclear Receptor Coactivators CBP and ACTR
Descriptor: CREB-BINDING PROTEIN, nuclear receptor coactivator
Authors:Demarest, S.J, Martinez-Yamout, M, Chung, J, Chen, H, Xu, W, Dyson, H.J, Evans, R.M, Wright, P.E.
Deposit date:2001-11-06
Release date:2002-02-06
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators.
Nature, 415, 2002
3NR1
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BU of 3nr1 by Molmil
A metazoan ortholog of SpoT hydrolyzes ppGpp and plays a role in starvation responses
Descriptor: HD domain-containing protein 3, MANGANESE (II) ION
Authors:Sun, D.W, Kim, H.Y, Kim, K.J, Jeon, Y.H, Chung, J.
Deposit date:2010-06-30
Release date:2010-09-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A metazoan ortholog of SpoT hydrolyzes ppGpp and functions in starvation responses
Nat.Struct.Mol.Biol., 17, 2010
1IE5
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BU of 1ie5 by Molmil
NMR STRUCTURE OF THE THIRD IMMUNOGLOBULIN DOMAIN FROM THE NEURAL CELL ADHESION MOLECULE.
Descriptor: NEURAL CELL ADHESION MOLECULE
Authors:Atkins, A.R, Chung, J, Deechongkit, S, Little, E.B, Edelman, G.M, Wright, P.E, Cunningham, B.A, Dyson, H.J.
Deposit date:2001-04-06
Release date:2001-08-08
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of the third immunoglobulin domain of the neural cell adhesion molecule N-CAM: can solution studies define the mechanism of homophilic binding?
J.Mol.Biol., 311, 2001
1DGQ
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BU of 1dgq by Molmil
NMR SOLUTION STRUCTURE OF THE INSERTED DOMAIN OF HUMAN LEUKOCYTE FUNCTION ASSOCIATED ANTIGEN-1
Descriptor: LEUKOCYTE FUNCTION ASSOCIATED ANTIGEN-1
Authors:Legge, G.B, Kriwacki, R.W, Chung, J, Hommel, U, Ramage, P, Case, D.A, Dyson, H.J, Wright, P.E.
Deposit date:1999-11-24
Release date:2000-02-03
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:NMR solution structure of the inserted domain of human leukocyte function associated antigen-1.
J.Mol.Biol., 295, 2000
1D5W
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BU of 1d5w by Molmil
PHOSPHORYLATED FIXJ RECEIVER DOMAIN
Descriptor: SULFATE ION, TRANSCRIPTIONAL REGULATORY PROTEIN FIXJ
Authors:Birck, C, Mourey, L, Gouet, P, Fabry, B, Schumacher, J, Rousseau, P, Kahn, D, Samama, J.P.
Deposit date:1999-10-12
Release date:2000-10-11
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Conformational changes induced by phosphorylation of the FixJ receiver domain.
Structure Fold.Des., 7, 1999
4OJ0
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BU of 4oj0 by Molmil
mCardinal V218E
Descriptor: Fluorescent protein FP480
Authors:Ataie, N, Ng, H.
Deposit date:2014-01-20
Release date:2014-03-19
Last modified:2014-05-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Non-invasive intravital imaging of cellular differentiation with a bright red-excitable fluorescent protein.
Nat.Methods, 11, 2014
8F66
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BU of 8f66 by Molmil
Thermoplasma acidophilum 20S proteasome - L81Y mutation in alpha subunit
Descriptor: Proteasome subunit alpha, Proteasome subunit beta
Authors:Chuah, J, Smith, D.
Deposit date:2022-11-16
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (2.28 Å)
Cite:High resolution structures define divergent and convergent mechanisms of archaeal proteasome activation.
Commun Biol, 6, 2023
8F7K
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BU of 8f7k by Molmil
Thermoplasma acidophilum 20S proteasome - wild type bound to ZYA
Descriptor: N-[(benzyloxy)carbonyl]-L-tyrosyl-D-alanine, Proteasome subunit alpha, Proteasome subunit beta
Authors:Chuah, J, Smith, D.
Deposit date:2022-11-18
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (1.94 Å)
Cite:High resolution structures define divergent and convergent mechanisms of archaeal proteasome activation.
Commun Biol, 6, 2023
8F6A
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BU of 8f6a by Molmil
Thermoplasma acidophilum 20S proteasome - wild type
Descriptor: Proteasome subunit alpha, Proteasome subunit beta
Authors:Chuah, J, Smith, D.
Deposit date:2022-11-16
Release date:2023-08-30
Method:ELECTRON MICROSCOPY (2.06 Å)
Cite:High resolution structures define divergent and convergent mechanisms of archaeal proteasome activation.
Commun Biol, 6, 2023
3P2F
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BU of 3p2f by Molmil
Crystal structure of TofI in an apo form
Descriptor: AHL synthase
Authors:Yu, S, Rhee, S.
Deposit date:2010-10-02
Release date:2011-07-06
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Small-molecule inhibitor binding to an N-acyl-homoserine lactone synthase
Proc.Natl.Acad.Sci.USA, 108, 2011
3P2H
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BU of 3p2h by Molmil
Crystal structure of TofI in a ternary complex with an inhibitor and MTA
Descriptor: 5'-DEOXY-5'-METHYLTHIOADENOSINE, AHL synthase, N-(3-oxocyclohex-1-en-1-yl)octanamide
Authors:Yu, S, Rhee, S.
Deposit date:2010-10-02
Release date:2011-07-06
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Small-molecule inhibitor binding to an N-acyl-homoserine lactone synthase
Proc.Natl.Acad.Sci.USA, 108, 2011
4X4M
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BU of 4x4m by Molmil
Structure of FcgammaRI in complex with Fc reveals the importance of glycan recognition for high affinity IgG binding
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Lu, J, Sun, P.D.
Deposit date:2014-12-03
Release date:2015-04-08
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.485 Å)
Cite:Structure of Fc gamma RI in complex with Fc reveals the importance of glycan recognition for high-affinity IgG binding.
Proc.Natl.Acad.Sci.USA, 112, 2015
5HZG
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BU of 5hzg by Molmil
The crystal structure of the strigolactone-induced AtD14-D3-ASK1 complex
Descriptor: (2Z)-2-methylbut-2-ene-1,4-diol, F-box/LRR-repeat MAX2 homolog, SKP1-like protein 1A, ...
Authors:Yao, R.F, Ming, Z.H, Yan, L.M, Rao, Z.H, Lou, Z.Y, Xie, D.X.
Deposit date:2016-02-02
Release date:2016-08-03
Last modified:2016-08-31
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:DWARF14 is a non-canonical hormone receptor for strigolactone
Nature, 536, 2016
5HYW
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BU of 5hyw by Molmil
The crystal structure of the D3-ASK1 complex
Descriptor: F-box/LRR-repeat MAX2 homolog, SKP1-like protein 1A
Authors:Yao, R.F, Ming, Z.H, Yan, L.M, Rao, Z.H, Lou, Z.Y, Xie, D.X.
Deposit date:2016-02-02
Release date:2016-08-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:DWARF14 is a non-canonical hormone receptor for strigolactone
Nature, 536, 2016
6THP
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BU of 6thp by Molmil
Neprilysin in complex with the inhibitor (R)-4-(1-carboxy-3-(3'-chlorobiphenyl-4-yl)propan-2-ylamino)-4-oxobutanoic acid
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[[(2~{R})-1-[4-(3-chlorophenyl)phenyl]-4-oxidanyl-4-oxidanylidene-butan-2-yl]amino]-4-oxidanylidene-butanoic acid, Neprilysin, ...
Authors:Schiering, N, Wiesmann, C.
Deposit date:2019-11-21
Release date:2020-02-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Structure-Guided Design of Substituted Biphenyl Butanoic Acid Derivatives as Neprilysin Inhibitors.
Acs Med.Chem.Lett., 11, 2020
6B3F
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BU of 6b3f by Molmil
Crystal Structure of HIV Protease complexed with N-(3-fluoro-2-(2-((2S,5S)-5-methyl-1-(phenylsulfonyl)piperazin-2-yl)ethyl)phenyl)-3,3-bis(4-fluorophenyl)propanamide
Descriptor: CHLORIDE ION, HIV-1 Protease, N-(3-fluoro-2-{2-[(2S,5S)-5-methyl-1-(phenylsulfonyl)piperazin-2-yl]ethyl}phenyl)-3,3-bis(4-fluorophenyl)propanamide
Authors:Su, H.P.
Deposit date:2017-09-21
Release date:2018-01-03
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Design and Synthesis of Piperazine Sulfonamide Cores Leading to Highly Potent HIV-1 Protease Inhibitors.
ACS Med Chem Lett, 8, 2017
6B38
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BU of 6b38 by Molmil
Crystal Structure of HIV Protease complexed with N-(3-fluoro-2-(2-((2S,6R)-6-methyl-1-(phenylsulfonyl)piperazin-2-yl)ethyl)phenyl)-3,3-bis(4-fluorophenyl)propanamide
Descriptor: CHLORIDE ION, HIV-1 Protease, N-(3-fluoro-2-{2-[(2S,6R)-6-methyl-1-(phenylsulfonyl)piperazin-2-yl]ethyl}phenyl)-3,3-bis(4-fluorophenyl)propanamide
Authors:Su, H.P.
Deposit date:2017-09-21
Release date:2018-01-03
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Design and Synthesis of Piperazine Sulfonamide Cores Leading to Highly Potent HIV-1 Protease Inhibitors.
ACS Med Chem Lett, 8, 2017
6B3G
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BU of 6b3g by Molmil
Crystal Structure of HIV Protease complexed with N-(3-fluoro-2-(2-((2S,6S)-6-methyl-1-(phenylsulfonyl)piperazin-2-yl)ethyl)phenyl)-3,3-bis(4-fluorophenyl)propanamide
Descriptor: CHLORIDE ION, HIV-1 Protease, N-(3-fluoro-2-{2-[(2S,6S)-6-methyl-1-(phenylsulfonyl)piperazin-2-yl]ethyl}phenyl)-3,3-bis(4-fluorophenyl)propanamide
Authors:Su, H.P.
Deposit date:2017-09-21
Release date:2018-01-03
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Design and Synthesis of Piperazine Sulfonamide Cores Leading to Highly Potent HIV-1 Protease Inhibitors.
ACS Med Chem Lett, 8, 2017
6B36
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BU of 6b36 by Molmil
Crystal Structure of HIV Protease complexed with (S)-N-(3-fluoro-2-(2-(1-(phenylsulfonyl)piperazin-2-yl)ethyl)phenyl)-3,3-bis(4-fluorophenyl)propanamide
Descriptor: (S)-N-(3-fluoro-2-(2-(1-(phenylsulfonyl)piperazin-2-yl)ethyl)phenyl)-3,3-bis(4-fluorophenyl)propanamide, CHLORIDE ION, HIV-1 Protease
Authors:Su, H.P.
Deposit date:2017-09-21
Release date:2018-01-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Design and Synthesis of Piperazine Sulfonamide Cores Leading to Highly Potent HIV-1 Protease Inhibitors.
ACS Med Chem Lett, 8, 2017

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