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8SAL
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BU of 8sal by Molmil
CryoEM structure of VRC01-CH848.0358.80
Descriptor: CH0848.3.D0358.80.06CHIM.DS.6R.SOSIP gp120, CH0848.3.D0358.80.06CHIM.DS.6R.SOSIP gp41, VCR01 variable heavy chain, ...
Authors:Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
Deposit date:2023-04-01
Release date:2023-04-19
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
8SB1
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BU of 8sb1 by Molmil
CryoEM structure of DH270.I3-CH848.10.17
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17 gp120, CH848.10.17.SOSIP gp41, ...
Authors:Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
Deposit date:2023-04-02
Release date:2023-04-19
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
8SAT
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BU of 8sat by Molmil
CryoEM structure of VRC01-CH848.10.17
Descriptor: CH848.10.17 gp120, CH848.10.17 gp41, VRC01-variable heavy chain, ...
Authors:Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
Deposit date:2023-04-02
Release date:2023-04-19
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
8SAS
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BU of 8sas by Molmil
CryoEM structure of DH270.5-CH848.10.17
Descriptor: CH848.10.17 gp120, CH848.10.17 gp41, DH270.5 variable heavy chian, ...
Authors:Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
Deposit date:2023-04-01
Release date:2023-04-19
Last modified:2023-05-31
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
8SB5
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BU of 8sb5 by Molmil
CryoEM structure of DH270.I1.6-CH848.10.17
Descriptor: CH848.10.17.SOSIP gp120, CH848.10.17.SOSIP gp41, DH270.I1.6 variable heavy chain, ...
Authors:Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P.
Deposit date:2023-04-02
Release date:2023-04-19
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage.
Nat Commun, 14, 2023
6XRJ
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BU of 6xrj by Molmil
Crystal structure of the disulfide linked DH717.1 Fab dimer, derived from a macaque HIV-1 vaccine-induced Env glycan-reactive neutralizing antibody B cell lineage
Descriptor: DH717.1 heavy chain Fab fragment, DH717.1 light chain Fab fragment
Authors:Manne, K, Nicely, N.I, Acharya, P.
Deposit date:2020-07-13
Release date:2020-12-30
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Cell, 184, 2021
2LP7
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BU of 2lp7 by Molmil
Structure of gp41-M-MAT, a membrane associated MPER trimer from HIV-1 gp41.
Descriptor: Envelope glycoprotein
Authors:Reardon, P.N.
Deposit date:2012-02-03
Release date:2013-02-06
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of an HIV-1-neutralizing antibody target, the lipid-bound gp41 envelope membrane proximal region trimer.
Proc.Natl.Acad.Sci.USA, 111, 2014
2M7W
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BU of 2m7w by Molmil
Independently verified structure of gp41-M-MAT, a membrane associated MPER trimer from HIV-1 gp41
Descriptor: Envelope glycoprotein
Authors:Martin, J.W, Reardon, P.N, Sage, H.S, Moses, D.S, Munir, A.S, Haynes, B.F, Spicer, L.D, Donald, B.R.
Deposit date:2013-05-01
Release date:2013-05-15
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of an HIV-1-neutralizing antibody target, the lipid-bound gp41 envelope membrane proximal region trimer.
Proc.Natl.Acad.Sci.USA, 111, 2014
7SG4
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BU of 7sg4 by Molmil
Structure of SARS-CoV S protein in complex with Receptor Binding Domain antibody DH1047
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DH1047 Heavy chain, DH1047 light chain, ...
Authors:Gobeil, S, Acharya, P.
Deposit date:2021-10-04
Release date:2021-11-10
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice.
Sci Transl Med, 14, 2022
7T17
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BU of 7t17 by Molmil
Zika Virus asymmetric unit bound with IgM antibody DH1017 Fab fragment
Descriptor: Core protein, DH1017.IgM FabC constant domain, DH1017.IgM IgH, ...
Authors:Miller, A.S, Kuhn, R.J.
Deposit date:2021-12-01
Release date:2022-11-23
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (5.26 Å)
Cite:A Zika virus-specific IgM elicited in pregnancy exhibits ultrapotent neutralization.
Cell, 185, 2022
4JAM
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BU of 4jam by Molmil
Crystal structure of broadly neutralizing anti-hiv-1 antibody ch103
Descriptor: 1,2-ETHANEDIOL, ANTIGEN BINDING FRAGMENT OF HEAVY CHAIN of CH103, ANTIGEN BINDING FRAGMENT OF LIGHT CHAIN of CH103, ...
Authors:Zhou, T, Moquin, S, Zheng, A, Srivatsan, S, Kwong, P.D.
Deposit date:2013-02-18
Release date:2013-04-03
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus.
Nature, 496, 2013
4JAN
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BU of 4jan by Molmil
crystal structure of broadly neutralizing antibody CH103 in complex with HIV-1 gp120
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIGEN BINDING FRAGMENT OF HEAVY CHAIN of CH103, ANTIGEN BINDING FRAGMENT OF LIGHT CHAIN of CH103, ...
Authors:Zhou, T, Moquin, S, Zheng, A, Srivatsan, S, Kwong, P.D.
Deposit date:2013-02-18
Release date:2013-04-03
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus.
Nature, 496, 2013
5U0U
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BU of 5u0u by Molmil
Crystal Structure of DH270.1 (unliganded, single-chain Fv) from the DH270 Broadly Neutralizing N332-glycan Dependent Lineage
Descriptor: DH270.1 single-chain variable fragment
Authors:Fera, D, Harrison, S.C.
Deposit date:2016-11-27
Release date:2017-03-15
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.428 Å)
Cite:Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.
Sci Transl Med, 9, 2017
5U15
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BU of 5u15 by Molmil
Crystal Structure of DH270.UCA3 (unliganded) from the DH270 Broadly Neutralizing N332-glycan Dependent Lineage
Descriptor: DH270.UCA3 heavy chain, DH270.UCA3 light chain
Authors:Fera, D, Harrison, S.C.
Deposit date:2016-11-27
Release date:2017-03-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.
Sci Transl Med, 9, 2017
5TQA
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BU of 5tqa by Molmil
Crystal Structure of DH270.6 (unliganded) from the DH270 Broadly Neutralizing N332-Glycan Dependent Lineage
Descriptor: DH270.6 Fab heavy chain, DH270.6 Fab light chain
Authors:Fera, D, Harrison, S.C.
Deposit date:2016-10-23
Release date:2017-03-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.723 Å)
Cite:Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.
Sci Transl Med, 9, 2017
5U0R
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BU of 5u0r by Molmil
Crystal Structure of DH270.UCA1 (unliganded) from the DH270 Broadly Neutralizing N332-glycan Dependent Lineage
Descriptor: DH270.UCA1 heavy chain, DH270.UCA1 light chain, SULFATE ION
Authors:Fera, D, Harrison, S.C.
Deposit date:2016-11-26
Release date:2017-03-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.295 Å)
Cite:Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.
Sci Transl Med, 9, 2017
5TPL
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BU of 5tpl by Molmil
Crystal Structure of DH270.3 (unliganded) from the DH270 Broadly Neutralizing N332-glycan Dependent Lineage
Descriptor: DH270.3 Fab heavy chain, DH270.3 Fab light chain
Authors:Fera, D, Harrison, S.C.
Deposit date:2016-10-20
Release date:2017-03-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.
Sci Transl Med, 9, 2017
5UKP
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BU of 5ukp by Molmil
Structure of unliganded anti-gp120 CD4bs antibody DH522.1 Fab
Descriptor: DH522.1 Fab fragment heavy chain, DH522.1 Fab fragment light chain
Authors:Nicely, N.I.
Deposit date:2017-01-23
Release date:2017-12-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations.
Nat Commun, 8, 2017
5UKN
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BU of 5ukn by Molmil
Structure of unliganded anti-gp120 CD4bs antibody DH522UCA Fab
Descriptor: CHLORIDE ION, DH522UCA Fab fragment heavy chain, DH522UCA Fab fragment light chain
Authors:Nicely, N.I.
Deposit date:2017-01-23
Release date:2017-12-06
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations.
Nat Commun, 8, 2017
5UKR
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BU of 5ukr by Molmil
Structure of unliganded anti-gp120 CD4bs antibody DH522.2 Fab in complex with a gp120 core
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Chimeric B.YU2 gp120 core derived from HIV-1 Env, DH522.2 Fab fragment heavy chain, ...
Authors:Nicely, N.I.
Deposit date:2017-01-23
Release date:2017-12-06
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.712 Å)
Cite:Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations.
Nat Commun, 8, 2017
5UKO
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BU of 5uko by Molmil
Structure of unliganded anti-gp120 CD4bs antibody DH522IA Fab
Descriptor: DH522IA Fab fragment heavy chain, DH522IA Fab fragment light chain
Authors:Nicely, N.I.
Deposit date:2017-01-23
Release date:2017-12-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations.
Nat Commun, 8, 2017
5TPP
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BU of 5tpp by Molmil
Crystal Structure of DH270.5 (unliganded) from the DH270 Broadly Neutralizing N332-glycan Dependent Lineage
Descriptor: CITRIC ACID, DH270.5 Fab heavy chain, DH270.5 Fab light chain, ...
Authors:Fera, D, Harrison, S.C.
Deposit date:2016-10-20
Release date:2017-03-15
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.
Sci Transl Med, 9, 2017
5TRP
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BU of 5trp by Molmil
Crystal Structure of the Unliganded DH270 Cooperating Lineage Member DH272
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DH272 Fab heavy chain, DH272 Fab light chain, ...
Authors:Fera, D, Harrison, S.C.
Deposit date:2016-10-27
Release date:2017-03-15
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.692 Å)
Cite:Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.
Sci Transl Med, 9, 2017
5UKQ
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BU of 5ukq by Molmil
Structure of unliganded anti-gp120 CD4bs antibody DH522.2 Fab
Descriptor: DH522.2 Fab fragment heavy chain, DH522.2 Fab fragment light chain, GLYCEROL
Authors:Nicely, N.I.
Deposit date:2017-01-23
Release date:2017-12-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations.
Nat Commun, 8, 2017
5DD1
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BU of 5dd1 by Molmil
Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques
Descriptor: ANTI-HIV ANTIBODY DH570 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570 FAB LIGHT CHAIN
Authors:Zhang, R, Verkoczy, L, Wiehe, K, Alam, S.M, Nicely, N.I, Santra, S, Bradley, T, Pemble, C, Gao, F, Montefiori, D.C, Bouton-Verville, H, Kelsoe, G, Parks, R, Foulger, A, Tomaras, G, Keple, T.B, Moody, M.A, Liao, H.-X, Haynes, B.F.
Deposit date:2015-08-24
Release date:2016-05-11
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.597 Å)
Cite:Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages.
Sci Transl Med, 8, 2016

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